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1
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33747613349
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Allergic rhinitis and sinusitis in asthma: Differential effects on symptoms and pulmonary function
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Dixon AE, Kaminsky DA, Holbrook JT, et al. Allergic rhinitis and sinusitis in asthma: differential effects on symptoms and pulmonary function. Chest 2006; 130:429-435.
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(2006)
Chest
, vol.130
, pp. 429-435
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Dixon, A.E.1
Kaminsky, D.A.2
Holbrook, J.T.3
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2
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34948867286
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Burgess JA, Walters EH, Byrnes GB, et al. Childhood allergic rhinitis predicts asthma incidence and persistence to middle age: a longitudinal study. J Allergy Clin Immunol 2007; 120:863-869. A longitudinal study of participants in the Tasmanian Asthma Study, originally enrolled in 1968, now followed over a 36-year period, which found that childhood allergic rhinitis increased likelihood of subsequently developing asthma and having persistent asthma into middle age.
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Burgess JA, Walters EH, Byrnes GB, et al. Childhood allergic rhinitis predicts asthma incidence and persistence to middle age: a longitudinal study. J Allergy Clin Immunol 2007; 120:863-869. A longitudinal study of participants in the Tasmanian Asthma Study, originally enrolled in 1968, now followed over a 36-year period, which found that childhood allergic rhinitis increased likelihood of subsequently developing asthma and having persistent asthma into middle age.
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3
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34548487314
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Early predictors for developing allergic disease and asthma: Examining separate steps in the 'allergic march'
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A report from the Childhood Asthma Prevention Study that examined predictors for developing asthma which found that eczema, but not wheeze, asthma or rhinitis predicted the subsequent development of sensitization
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Almqvist C, Li Q, Britton WJ, et al. Early predictors for developing allergic disease and asthma: examining separate steps in the 'allergic march'. Clin Exp Allergy 2007; 37:1296-1302. A report from the Childhood Asthma Prevention Study that examined predictors for developing asthma which found that eczema, but not wheeze, asthma or rhinitis predicted the subsequent development of sensitization.
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(2007)
Clin Exp Allergy
, vol.37
, pp. 1296-1302
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Almqvist, C.1
Li, Q.2
Britton, W.J.3
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4
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35349025383
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Skin prick test can identify eczematous infants at risk of asthma and allergic rhinitis
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A study of an Australian birth cohort which found that atopy in children with eczema predicted the development of childhood asthma
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Lowe AJ, Hosking CS, Bennett CM, et al. Skin prick test can identify eczematous infants at risk of asthma and allergic rhinitis. Clin Exp Allergy 2007;37:1624-1631. A study of an Australian birth cohort which found that atopy in children with eczema predicted the development of childhood asthma.
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(2007)
Clin Exp Allergy
, vol.37
, pp. 1624-1631
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Lowe, A.J.1
Hosking, C.S.2
Bennett, C.M.3
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5
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44649162474
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Cigarette smoking is associated with a greater risk of incident asthma in allergic rhinitis
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A study of an Italian adult population followed at an outpatient allergy clinic which reports that smoking predicts the later development of asthma in patients with allergic rhinitis
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Polosa R, Knoke JD, Russo C, et al. Cigarette smoking is associated with a greater risk of incident asthma in allergic rhinitis. J Allergy Clin Immunol 2008; 121:1428-1434. A study of an Italian adult population followed at an outpatient allergy clinic which reports that smoking predicts the later development of asthma in patients with allergic rhinitis.
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(2008)
J Allergy Clin Immunol
, vol.121
, pp. 1428-1434
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Polosa, R.1
Knoke, J.D.2
Russo, C.3
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6
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0344065387
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Prospective study of body mass index, weight change, and risk of adult-onset asthma in women
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Camargo CA Jr, Weiss ST, Zhang S, et al. Prospective study of body mass index, weight change, and risk of adult-onset asthma in women. Arch Intern Med 1999; 159:2582-2588.
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Arch Intern Med
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Camargo Jr, C.A.1
Weiss, S.T.2
Zhang, S.3
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7
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40949120616
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Obesity and adult asthma: Potential effect modification by gender, but not by hay fever
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Loerbroks A, Apfelbacher CJ, Amelang M, Sturmer T. Obesity and adult asthma: potential effect modification by gender, but not by hay fever. Ann Epidemiol 2008; 18:283-289.
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(2008)
Ann Epidemiol
, vol.18
, pp. 283-289
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Loerbroks, A.1
Apfelbacher, C.J.2
Amelang, M.3
Sturmer, T.4
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8
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34248548648
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Diagnostic classification of persistent rhinitis and its relationship to exhaled nitric oxide and asthma: A clinical study of a consecutive series of patients
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A study of patients referred to an allergy clinic for nasal symptoms. It found that asthma was significantly more common in allergic rhinitis and chronic rhinosinusitis than in patient with nonallergic rhinitis
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Rolla G, Guida G, Heffler E, et al. Diagnostic classification of persistent rhinitis and its relationship to exhaled nitric oxide and asthma: a clinical study of a consecutive series of patients. Chest 2007; 131:1345-1352. A study of patients referred to an allergy clinic for nasal symptoms. It found that asthma was significantly more common in allergic rhinitis and chronic rhinosinusitis than in patient with nonallergic rhinitis.
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(2007)
Chest
, vol.131
, pp. 1345-1352
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Rolla, G.1
Guida, G.2
Heffler, E.3
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9
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34548539012
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The prevalence and effect of asthma on adults with chronic rhinosinusitis
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A cross-sectional study of 145 patients referred to an otolaryngology clinic for chronic rhinosinusitis which found that nasal polyps and symptoms such as nasal congestion were significantly more common in asthmatics than nonasthmatics
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Seybt MW, McMains KC, Kountakis SE. The prevalence and effect of asthma on adults with chronic rhinosinusitis. Ear Nose Throat J 2007; 86:409-411. A cross-sectional study of 145 patients referred to an otolaryngology clinic for chronic rhinosinusitis which found that nasal polyps and symptoms such as nasal congestion were significantly more common in asthmatics than nonasthmatics.
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(2007)
Ear Nose Throat J
, vol.86
, pp. 409-411
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Seybt, M.W.1
McMains, K.C.2
Kountakis, S.E.3
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10
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41349084011
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Bugten V, Nordgard S, Romundstad P, Steinsvag S. Chronic rhinosinusitis and nasal polyposis: indicia of heterogeneity. Rhinology 2008; 46:40-44. A study of 102 patients undergoing function endoscopy sinus surgery; the authors reported that asthma was significantly more common in patients with nasal polyps than patients with chronic rhinosinusitis.
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Bugten V, Nordgard S, Romundstad P, Steinsvag S. Chronic rhinosinusitis and nasal polyposis: indicia of heterogeneity. Rhinology 2008; 46:40-44. A study of 102 patients undergoing function endoscopy sinus surgery; the authors reported that asthma was significantly more common in patients with nasal polyps than patients with chronic rhinosinusitis.
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11
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48849087975
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Chronic rhinosinusitis: Risk factors for the recurrence of chronic rhinosinusitis based on 5-year follow-up after endoscopic sinus surgery
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Matsuwaki Y, Ookushi T, Asaka D, et al. Chronic rhinosinusitis: risk factors for the recurrence of chronic rhinosinusitis based on 5-year follow-up after endoscopic sinus surgery. Int Arch Allergy Immunol 2008; 146 (Suppl 1): 77-81.
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(2008)
Int Arch Allergy Immunol
, vol.146
, Issue.SUPPL. 1
, pp. 77-81
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Matsuwaki, Y.1
Ookushi, T.2
Asaka, D.3
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12
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43549118588
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Gene expression profiling of nasal polyps associated with chronic sinusitis and aspirin-sensitive asthma
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A genome-wide microarray of sinonasal mucosa from normal controls compared with patients with chronic rhinosinuisitis alone and chronic rhinosinusitis with asthma; the study found a similar pattern of gene expression in both populations with chronic rhinosinuisitis, which was distinct from healthy controls
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Stankovic KM, Goldsztein H, Reh DD, et al. Gene expression profiling of nasal polyps associated with chronic sinusitis and aspirin-sensitive asthma. Laryngoscope 2008; 118:881-889. A genome-wide microarray of sinonasal mucosa from normal controls compared with patients with chronic rhinosinuisitis alone and chronic rhinosinusitis with asthma; the study found a similar pattern of gene expression in both populations with chronic rhinosinuisitis, which was distinct from healthy controls.
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(2008)
Laryngoscope
, vol.118
, pp. 881-889
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Stankovic, K.M.1
Goldsztein, H.2
Reh, D.D.3
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13
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41749101535
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Lack of control of severe asthma is associated with co-existence of moderate-to-severe rhinitis
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This prospective cohort study of patients with severe asthma found that severity of rhinitis was associated with poor asthma control and asthma exacerbations
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Ponte EV, Franco R, Nascimento HF, et al. Lack of control of severe asthma is associated with co-existence of moderate-to-severe rhinitis. Allergy 2008; 63:564-569. This prospective cohort study of patients with severe asthma found that severity of rhinitis was associated with poor asthma control and asthma exacerbations.
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(2008)
Allergy
, vol.63
, pp. 564-569
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Ponte, E.V.1
Franco, R.2
Nascimento, H.F.3
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14
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44949146498
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Blood and sputum eosinophil levels in asthma and their relationship to sinus computed tomographic findings
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This retrospective review of asthmatic patients with sinus CT and blood and sputum eosinophil data available found a positive relationship between eosinophils and severity of sinus disease
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Mehta V, Campeau NG, Kita H, Hagan JB. Blood and sputum eosinophil levels in asthma and their relationship to sinus computed tomographic findings. Mayo Clin Proc 2008; 83:671-678. This retrospective review of asthmatic patients with sinus CT and blood and sputum eosinophil data available found a positive relationship between eosinophils and severity of sinus disease.
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(2008)
Mayo Clin Proc
, vol.83
, pp. 671-678
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Mehta, V.1
Campeau, N.G.2
Kita, H.3
Hagan, J.B.4
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15
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33846786917
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Comparison of deltaFVC between patients with allergic rhinitis with airway hypersensitivity and patients with mild asthma
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Choi SH, Kim do K, Yoo Y, et al. Comparison of deltaFVC between patients with allergic rhinitis with airway hypersensitivity and patients with mild asthma. Ann Allergy Asthma Immunol 2007; 98:128-133.
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(2007)
Ann Allergy Asthma Immunol
, vol.98
, pp. 128-133
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Choi, S.H.1
Kim do, K.2
Yoo, Y.3
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16
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38949092468
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Impact of allergic rhinitis on asthma: Effects on spirometric parameters
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This prospective study of naval personnel found that duration of allergic rhinitis and sensitization to house mites were significantly associated with impaired lung function
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Ciprandi G, Cirillo I, Pistorio A. Impact of allergic rhinitis on asthma: effects on spirometric parameters. Allergy 2008; 63:255-260. This prospective study of naval personnel found that duration of allergic rhinitis and sensitization to house mites were significantly associated with impaired lung function.
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(2008)
Allergy
, vol.63
, pp. 255-260
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Ciprandi, G.1
Cirillo, I.2
Pistorio, A.3
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17
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38949199699
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Airway responsiveness to methacholine and deep inhalations in subjects with rhinitis without asthma
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This was a study of 10 healthy individuals and 10 patients with rhinitis without asthma, looking at the effects of a deep breath on responsiveness to methacholine; the effect of a deep breath was attenuated in those with rhinitis compared with healthy people
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Crimi E, Saporiti R, Bartolini S, et al. Airway responsiveness to methacholine and deep inhalations in subjects with rhinitis without asthma. J Allergy Clin Immunol 2008; 121:403-407. This was a study of 10 healthy individuals and 10 patients with rhinitis without asthma, looking at the effects of a deep breath on responsiveness to methacholine; the effect of a deep breath was attenuated in those with rhinitis compared with healthy people.
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(2008)
J Allergy Clin Immunol
, vol.121
, pp. 403-407
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Crimi, E.1
Saporiti, R.2
Bartolini, S.3
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18
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0037297866
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Bronchodilation and bronchoprotection by deep inspiration and their relationship to bronchial hyperresponsiveness
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Skloot G, Togias A. Bronchodilation and bronchoprotection by deep inspiration and their relationship to bronchial hyperresponsiveness. Clin Rev Allergy Immunol 2003; 24:55-72.
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(2003)
Clin Rev Allergy Immunol
, vol.24
, pp. 55-72
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Skloot, G.1
Togias, A.2
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19
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34748839579
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Peripheral nitric oxide is increased in rhinitic patients with asthma compared to bronchial hyperresponsiveness
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A study that compared patients with rhinitis only, rhinitis and bronchial hyperreactivity and rhinitis and asthma, and found trend towards progressive increase in peripheral nitric oxide which correlated with peripheral obstruction in response to methacholine
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Tufvesson E, Aronsson D, Ankerst J, et al. Peripheral nitric oxide is increased in rhinitic patients with asthma compared to bronchial hyperresponsiveness. Respir Med 2007; 101:2321-2326. A study that compared patients with rhinitis only, rhinitis and bronchial hyperreactivity and rhinitis and asthma, and found trend towards progressive increase in peripheral nitric oxide which correlated with peripheral obstruction in response to methacholine.
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(2007)
Respir Med
, vol.101
, pp. 2321-2326
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Tufvesson, E.1
Aronsson, D.2
Ankerst, J.3
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20
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34250691571
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Cysteinyl-leukotriene levels in sputum differentiate asthma from rhinitis patients with or without bronchial hyperresponsiveness
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This study compared asthmatics, rhinitis with bronchial hyperreactivity, rhinitics without bronchial hyperreactivity and normal controls, and found increased cysteinyl leukotrienes and hyaluronan in the sputum of asthmatics compared with other groups
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Tufvesson E, Aronsson D, Bjermer L. Cysteinyl-leukotriene levels in sputum differentiate asthma from rhinitis patients with or without bronchial hyperresponsiveness. Clin Exp Allergy 2007; 37:1067-1073. This study compared asthmatics, rhinitis with bronchial hyperreactivity, rhinitics without bronchial hyperreactivity and normal controls, and found increased cysteinyl leukotrienes and hyaluronan in the sputum of asthmatics compared with other groups.
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(2007)
Clin Exp Allergy
, vol.37
, pp. 1067-1073
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Tufvesson, E.1
Aronsson, D.2
Bjermer, L.3
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21
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38949103695
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Sohn SW, Lee HS, Park HW, et al. Evaluation of cytokine mRNA in induced sputum from patients with allergic rhinitis: relationship to airway hyperresponsiveness. Allergy 2008; 63:268-273. This cross-sectional study of patients with allergic rhinitis only, allergic rhinitis with bronchial hyperreactivity and asthma found progressive increase in IL-5 and vascular endothelial growth factor across the three groups.
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Sohn SW, Lee HS, Park HW, et al. Evaluation of cytokine mRNA in induced sputum from patients with allergic rhinitis: relationship to airway hyperresponsiveness. Allergy 2008; 63:268-273. This cross-sectional study of patients with allergic rhinitis only, allergic rhinitis with bronchial hyperreactivity and asthma found progressive increase in IL-5 and vascular endothelial growth factor across the three groups.
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22
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34247382142
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Lower airways inflammation in allergic rhinitics: A comparison with asthmatics and normal controls
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A cross-sectional study of endobroncial biopsies from normal controls, allergic rhinitis and patients with asthma; there was progressive airway inflammation across the three groups
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Brown JL, Behndig AF, Sekerel BE, et al. Lower airways inflammation in allergic rhinitics: a comparison with asthmatics and normal controls. Clin Exp Allergy 2007; 37:688-695. A cross-sectional study of endobroncial biopsies from normal controls, allergic rhinitis and patients with asthma; there was progressive airway inflammation across the three groups.
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(2007)
Clin Exp Allergy
, vol.37
, pp. 688-695
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Brown, J.L.1
Behndig, A.F.2
Sekerel, B.E.3
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23
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0035096259
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Nasal allergen provocation induces adhesion molecule expression and tissue eosinophilia in upper and lower airways
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Braunstahl GJ, Overbeek SE, Kleinjan A, et al. Nasal allergen provocation induces adhesion molecule expression and tissue eosinophilia in upper and lower airways. J Allergy Clin Immunol 2001; 107:469-476.
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(2001)
J Allergy Clin Immunol
, vol.107
, pp. 469-476
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Braunstahl, G.J.1
Overbeek, S.E.2
Kleinjan, A.3
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24
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34249777544
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Lower airway inflamma- tion before and after house dust mite nasal challenge: An age and allergen exposure-related phenomenon
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A comparison of upper and lower airway response to dust mite nasal challenge in healthy control, allergic asthmatic and rhinitic children studied both during winter and summer months
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Marcucci F, Passalacqua G, Canonica GW, et al. Lower airway inflamma- tion before and after house dust mite nasal challenge: an age and allergen exposure-related phenomenon. Respir Med 2007; 101:1600-1608. A comparison of upper and lower airway response to dust mite nasal challenge in healthy control, allergic asthmatic and rhinitic children studied both during winter and summer months.
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(2007)
Respir Med
, vol.101
, pp. 1600-1608
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Marcucci, F.1
Passalacqua, G.2
Canonica, G.W.3
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25
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1442349742
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Kinetics of bone marrow eosinophilopoiesis and associated cytokines after allergen inhalation
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Dorman SC, Sehmi R, Gauvreau GM, et al. Kinetics of bone marrow eosinophilopoiesis and associated cytokines after allergen inhalation. Am J Respir Crit Care Med 2004; 169:565-572.
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Am J Respir Crit Care Med
, vol.169
, pp. 565-572
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Dorman, S.C.1
Sehmi, R.2
Gauvreau, G.M.3
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26
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0034781818
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Allergen-induced murine upper airway inflammation: Local and systemic changes in murine experimental allergic rhinitis
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Saito H, Howie K, Wattle J, et al. Allergen-induced murine upper airway inflammation: local and systemic changes in murine experimental allergic rhinitis. Immunology 2001; 104:226-234.
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(2001)
Immunology
, vol.104
, pp. 226-234
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Saito, H.1
Howie, K.2
Wattle, J.3
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27
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14644408732
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Haemopoietic mechanisms in murine allergic upper and lower airway inflammation
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Li J, Saito H, Crawford L, et al. Haemopoietic mechanisms in murine allergic upper and lower airway inflammation. Immunology 2005; 114:386-396.
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(2005)
Immunology
, vol.114
, pp. 386-396
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Li, J.1
Saito, H.2
Crawford, L.3
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28
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37349024029
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Impact of nasal condition on selfassessed disease control and treatment satisfaction in patients with asthma complicated by allergic rhinitis
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Koga T, Matsuse H, Kohrogi H, et al. Impact of nasal condition on selfassessed disease control and treatment satisfaction in patients with asthma complicated by allergic rhinitis. Allergol Int 2007; 56:427-431.
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(2007)
Allergol Int
, vol.56
, pp. 427-431
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Koga, T.1
Matsuse, H.2
Kohrogi, H.3
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29
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38949181519
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Frequency and impact of allergic rhinitis in asthma patients in everyday general medical practice: A French observational cross-sectional study
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Magnan A, Meunier JP, Saugnac C, et al. Frequency and impact of allergic rhinitis in asthma patients in everyday general medical practice: a French observational cross-sectional study. Allergy 2008; 63:292-298.
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Allergy
, vol.63
, pp. 292-298
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Magnan, A.1
Meunier, J.P.2
Saugnac, C.3
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30
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34447132918
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Jacobsen L, Niggemann B, Dreborg S, et al. Specific immunotherapy has long-term preventive effect of seasonal and perennial asthma: 10-year followup on the PAT study. Allergy 2007; 62:943-948. This study reported on the long-term effects of specific immunotherapy. At baseline, children were randomized to treatment subcutaneous specific immunotherapy or no therapy. Seven years after completion of immunotherapy, there was a significantly reduced risk of developing asthma in the treated group.
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Jacobsen L, Niggemann B, Dreborg S, et al. Specific immunotherapy has long-term preventive effect of seasonal and perennial asthma: 10-year followup on the PAT study. Allergy 2007; 62:943-948. This study reported on the long-term effects of specific immunotherapy. At baseline, children were randomized to treatment subcutaneous specific immunotherapy or no therapy. Seven years after completion of immunotherapy, there was a significantly reduced risk of developing asthma in the treated group.
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31
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38149008332
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Abnormal spirometry in children with persistent allergic rhinitis due to mite sensitization: The benefit of nasal corticosteroids
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This was an uncontrolled study on the effects of nasal steroids for treatment of allergic rhinitis on lung function in children that found improvement in measures of airflow obstruction with treatment
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Kessel A, Halloun H, Bamberger E, et al. Abnormal spirometry in children with persistent allergic rhinitis due to mite sensitization: the benefit of nasal corticosteroids. Pediatr Allergy Immunol 2008; 19:61-66. This was an uncontrolled study on the effects of nasal steroids for treatment of allergic rhinitis on lung function in children that found improvement in measures of airflow obstruction with treatment.
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(2008)
Pediatr Allergy Immunol
, vol.19
, pp. 61-66
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Kessel, A.1
Halloun, H.2
Bamberger, E.3
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32
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1542721512
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Rhinitis therapy and the prevention of hospital care for asthma: A case-control study
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Corren J, Manning BE, Thompson SF, et al. Rhinitis therapy and the prevention of hospital care for asthma: a case-control study. J Allergy Clin Immunol 2004; 113:415-419.
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(2004)
J Allergy Clin Immunol
, vol.113
, pp. 415-419
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Corren, J.1
Manning, B.E.2
Thompson, S.F.3
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33
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0036155192
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Treating allergic rhinitis in patients with comorbid asthma: The risk of asthma-related hospitalizations and emergency department visits
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Crystal-Peters J, Neslusan C, Crown WH, Torres A. Treating allergic rhinitis in patients with comorbid asthma: the risk of asthma-related hospitalizations and emergency department visits. J Allergy Clin Immunol 2002; 109:57-62.
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(2002)
J Allergy Clin Immunol
, vol.109
, pp. 57-62
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Crystal-Peters, J.1
Neslusan, C.2
Crown, W.H.3
Torres, A.4
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34
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Fluticasone propionate nasal spray is superior to montelukast for allergic rhinitis while neither affects overall asthma control
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Nathan RA, Yancey SW, Waitkus-Edwards K, et al. Fluticasone propionate nasal spray is superior to montelukast for allergic rhinitis while neither affects overall asthma control. Chest 2005; 128:1910-1920.
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(2005)
Chest
, vol.128
, pp. 1910-1920
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Nathan, R.A.1
Yancey, S.W.2
Waitkus-Edwards, K.3
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35
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41849125634
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Effect of nasal steroid treatment on airway inflammation determined by exhaled nitric oxide in allergic schoolchildren with perennial rhinitis and asthma
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A randomized placebo controlled trial of nasal steroids in 40 children with allergic rhinitis and asthma. The investigators found improvement in nasal measures of inflammation, but no changes in lower airway inflammation measured by exhaled nitric oxide
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Pedroletti C, Lundahl J, Alving K, Hedlin G. Effect of nasal steroid treatment on airway inflammation determined by exhaled nitric oxide in allergic schoolchildren with perennial rhinitis and asthma. Pediatr Allergy Immunol 2008; 19:219-226. A randomized placebo controlled trial of nasal steroids in 40 children with allergic rhinitis and asthma. The investigators found improvement in nasal measures of inflammation, but no changes in lower airway inflammation (measured by exhaled nitric oxide).
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(2008)
Pediatr Allergy Immunol
, vol.19
, pp. 219-226
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Pedroletti, C.1
Lundahl, J.2
Alving, K.3
Hedlin, G.4
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36
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0037329163
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Effect of nasal triamcinolone acetonide on lower airway inflammatory markers in patients with allergic rhinitis
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Sandrini A, Ferreira IM, Jardim JR, et al. Effect of nasal triamcinolone acetonide on lower airway inflammatory markers in patients with allergic rhinitis. J Allergy Clin Immunol 2003; 111:313-320.
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J Allergy Clin Immunol
, vol.111
, pp. 313-320
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Sandrini, A.1
Ferreira, I.M.2
Jardim, J.R.3
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37
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42449123137
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Asthma outcomes after endoscopic sinus surgery in aspirin-tolerant versus aspirin-induced asthmatic patients
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Awad OG, Fasano MB, Lee JH, Graham SM. Asthma outcomes after endoscopic sinus surgery in aspirin-tolerant versus aspirin-induced asthmatic patients. Am J Rhinol 2008; 22:197-203.
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(2008)
Am J Rhinol
, vol.22
, pp. 197-203
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Awad, O.G.1
Fasano, M.B.2
Lee, J.H.3
Graham, S.M.4
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