메뉴 건너뛰기




Volumn 21, Issue 4, 2008, Pages 451-457

CpG used as an adjuvant for an adenovirus-based Venezuelan equine encephalitis virus vaccine increases the immune response to the vector, but not to the transgene product

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ADJUVANT; ANTIBODY; ANTIGEN; CPG OLIGODEOXYNUCLEOTIDE; GENE PRODUCT; UNCLASSIFIED DRUG; VENEZUELAN EQUINE ENCEPHALOMYELITIS ALPHAVIRUS VACCINE; VIRUS VACCINE;

EID: 58149252368     PISSN: 08828245     EISSN: None     Source Type: Journal    
DOI: 10.1089/vim.2008.0052     Document Type: Article
Times cited : (9)

References (69)
  • 1
    • 58149272808 scopus 로고    scopus 로고
    • The Emerging BW Threat: Lessons from the Russian Offensive BW R&D Program, 1945
    • Alabama
    • Alibek K: The Emerging BW Threat: Lessons from the Russian Offensive BW R&D Program, 1945 to 1992. Maxwell AFB, Alabama, 1999.
    • (1999) to 1992. Maxwell AFB
    • Alibek, K.1
  • 2
    • 33645999981 scopus 로고    scopus 로고
    • Innate immunity at the mucosal surface: Role of toll-like receptor 3 and toll-like receptor 9 in cervical epithelial cell responses to microbial pathogens
    • Andersen JM, Al-Khairy D, and Ingalls RR: Innate immunity at the mucosal surface: Role of toll-like receptor 3 and toll-like receptor 9 in cervical epithelial cell responses to microbial pathogens. Biol Reprod 2006;74:824-831.
    • (2006) Biol Reprod , vol.74 , pp. 824-831
    • Andersen, J.M.1    Al-Khairy, D.2    Ingalls, R.R.3
  • 3
    • 0041707861 scopus 로고    scopus 로고
    • Plasmid chemokines and colony-stimulating factors enhance the immunogenicity of DNA priming-viral vector boosting human immunodeficiency virus type 1 vaccines
    • Barouch DH, Mckay PF, Sumida SM, et al.: Plasmid chemokines and colony-stimulating factors enhance the immunogenicity of DNA priming-viral vector boosting human immunodeficiency virus type 1 vaccines. J Virol 2003;77:8729-8735.
    • (2003) J Virol , vol.77 , pp. 8729-8735
    • Barouch, D.H.1    Mckay, P.F.2    Sumida, S.M.3
  • 4
    • 2442611810 scopus 로고    scopus 로고
    • Immunogenicity of recombinant adenovirus serotype 35 vaccine in the presence of pre-existing anti-Ad5 immunity
    • Barouch DH, Pau MG, Custers JHHV, et al.: Immunogenicity of recombinant adenovirus serotype 35 vaccine in the presence of pre-existing anti-Ad5 immunity. J Immunol 2004;172:6290-6297.
    • (2004) J Immunol , vol.172 , pp. 6290-6297
    • Barouch, D.H.1    Pau, M.G.2    Custers, J.H.H.V.3
  • 5
    • 0033551132 scopus 로고    scopus 로고
    • Mucosal vaccination overcomes the barrier to recombinant vaccinia immunization caused by preexisting poxvirus immunity
    • Belyakov IM, Moss B, Strober W, and Berzofsky JA: Mucosal vaccination overcomes the barrier to recombinant vaccinia immunization caused by preexisting poxvirus immunity. Proc Natl Acad Sci USA 1999;96:4512-4517.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 4512-4517
    • Belyakov, I.M.1    Moss, B.2    Strober, W.3    Berzofsky, J.A.4
  • 6
    • 0041923582 scopus 로고    scopus 로고
    • Shared modes of protection against poxvirus infection by attenuated and conventional smallpox vaccine viruses
    • Belyakov IM, Earl P, Dzutsev A, et al.: Shared modes of protection against poxvirus infection by attenuated and conventional smallpox vaccine viruses. Proc Natl Acad Sci USA 2003;100:9458-9463.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 9458-9463
    • Belyakov, I.M.1    Earl, P.2    Dzutsev, A.3
  • 7
    • 33750301915 scopus 로고    scopus 로고
    • + T cell immunity in the lung by CpG oligodeoxynucleotides increases protective efficacy of a modified vaccinia Ankara vaccine against lethal poxvirus infection even in a CD4-deficient host
    • + T cell immunity in the lung by CpG oligodeoxynucleotides increases protective efficacy of a modified vaccinia Ankara vaccine against lethal poxvirus infection even in a CD4-deficient host. J Immunol 2006;177:6336-6343.
    • (2006) J Immunol , vol.177 , pp. 6336-6343
    • Belyakov, I.M.1    Isakov, D.2    Zhu, Q.3    Dzutsev, A.4    Klinman, D.5    Berzofsky, J.A.6
  • 8
    • 0034666692 scopus 로고    scopus 로고
    • An immunological profile of Balb/c mice protected from airborne challenge following vaccination with a live attenuated Venezuelan equine encephalitis virus vaccine
    • Bennett AM, Elvin SJ, Wright AJ, Jones SM, and Phillpotts RJ: An immunological profile of Balb/c mice protected from airborne challenge following vaccination with a live attenuated Venezuelan equine encephalitis virus vaccine. Vaccine 2000;19:337-347.
    • (2000) Vaccine , vol.19 , pp. 337-347
    • Bennett, A.M.1    Elvin, S.J.2    Wright, A.J.3    Jones, S.M.4    Phillpotts, R.J.5
  • 9
    • 38449085650 scopus 로고    scopus 로고
    • Characterization of antigen-specific immune responses induced by Canary-pox virus vaccines
    • Bos R, Van Duikeren S, Van Hall T, et al.: Characterization of antigen-specific immune responses induced by Canary-pox virus vaccines. J Immunol 2007;179:6115-6122.
    • (2007) J Immunol , vol.179 , pp. 6115-6122
    • Bos, R.1    Van Duikeren, S.2    Van Hall, T.3
  • 10
    • 0038664390 scopus 로고    scopus 로고
    • Comparative immunogenicity in rhesus monkeys of DNA plasmid, recombinant vaccinia virus, and replication-defective adenovirus vectors expressing a human immunodeficiency virus type 1 gag gene
    • Casimiro DR, Chen L, Fu TM, et al.: Comparative immunogenicity in rhesus monkeys of DNA plasmid, recombinant vaccinia virus, and replication-defective adenovirus vectors expressing a human immunodeficiency virus type 1 gag gene. J Virol 2003;77:6305-6313.
    • (2003) J Virol , vol.77 , pp. 6305-6313
    • Casimiro, D.R.1    Chen, L.2    Fu, T.M.3
  • 11
    • 11344257404 scopus 로고    scopus 로고
    • CPG 7909, an immunostimulatory TLR9 agonist oligodeoxynucleotide, as adjuvant to Engerix-B® HBV vaccine in healthy adults: A double-blind phase I/II study
    • Cooper CL, Davis HL, Morris ML, et al.: CPG 7909, an immunostimulatory TLR9 agonist oligodeoxynucleotide, as adjuvant to Engerix-B® HBV vaccine in healthy adults: A double-blind phase I/II study. J Clin Immunol 2004;24:693-701.
    • (2004) J Clin Immunol , vol.24 , pp. 693-701
    • Cooper, C.L.1    Davis, H.L.2    Morris, M.L.3
  • 12
    • 3843052308 scopus 로고    scopus 로고
    • Safety and immunogenicity of CPG 7909 injection as an adjuvant to Fluarix influenza vaccine
    • Cooper CL, Davis HL, Morris ML, et al.: Safety and immunogenicity of CPG 7909 injection as an adjuvant to Fluarix influenza vaccine. Vaccine 2004;22:3136-3143.
    • (2004) Vaccine , vol.22 , pp. 3136-3143
    • Cooper, C.L.1    Davis, H.L.2    Morris, M.L.3
  • 13
    • 33746256898 scopus 로고    scopus 로고
    • TLR2 engagement on CD8 T cells lowers the threshold for optimal antigen-induced T cell activation
    • Cottalorda A, Verschelde C, Marcais A, et al.: TLR2 engagement on CD8 T cells lowers the threshold for optimal antigen-induced T cell activation. Eur J Immunol 2006;36:1684-1693.
    • (2006) Eur J Immunol , vol.36 , pp. 1684-1693
    • Cottalorda, A.1    Verschelde, C.2    Marcais, A.3
  • 14
    • 0003030962 scopus 로고
    • Two human cases of laboratory infection with Mucambo virus
    • de Mucha-Macias J, and Sanchez-Spindola I: Two human cases of laboratory infection with Mucambo virus. Am J Trop Med Hyg 1965;14:475-478.
    • (1965) Am J Trop Med Hyg , vol.14 , pp. 475-478
    • de Mucha-Macias, J.1    Sanchez-Spindola, I.2
  • 15
    • 0018387631 scopus 로고
    • Ten clinical cases of human infection with Venezuelan equine encephalomyelitis virus, subtype I-D
    • Dietz WHJ, Peralta PH, and Johnson KM: Ten clinical cases of human infection with Venezuelan equine encephalomyelitis virus, subtype I-D. Am J Trop Med Hyg 1979;28:329-334.
    • (1979) Am J Trop Med Hyg , vol.28 , pp. 329-334
    • Dietz, W.H.J.1    Peralta, P.H.2    Johnson, K.M.3
  • 16
    • 0036274001 scopus 로고    scopus 로고
    • Role for mucosal immune responses and cell-mediated immune functions in protection from airborne challenge with Venezuelan equine encephalitis virus
    • Elvin SJ, Bennett AM, and Phillpotts RJ: Role for mucosal immune responses and cell-mediated immune functions in protection from airborne challenge with Venezuelan equine encephalitis virus. J Med Virol 2002;67:384-393.
    • (2002) J Med Virol , vol.67 , pp. 384-393
    • Elvin, S.J.1    Bennett, A.M.2    Phillpotts, R.J.3
  • 17
  • 18
    • 33845195783 scopus 로고    scopus 로고
    • Increased potency of BioThrax® anthrax vaccine with the addition of the C-class CpG oligonucleotide adjuvant CPG 10109
    • Gu M, Hine PM, James Jackson W, Giri L, and Nabors GS: Increased potency of BioThrax® anthrax vaccine with the addition of the C-class CpG oligonucleotide adjuvant CPG 10109. Vaccine 2007;25:526-534.
    • (2007) Vaccine , vol.25 , pp. 526-534
    • Gu, M.1    Hine, P.M.2    James Jackson, W.3    Giri, L.4    Nabors, G.S.5
  • 19
    • 84925026128 scopus 로고
    • Measurement of the respiratory volume of laboratory animals
    • Guyton AC: Measurement of the respiratory volume of laboratory animals. Am J Physiol 1947;150:70-77.
    • (1947) Am J Physiol , vol.150 , pp. 70-77
    • Guyton, A.C.1
  • 20
    • 28344457315 scopus 로고    scopus 로고
    • Comparison of the safety and immunogenicity of hepatitis B virus surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide and a licensed hepatitis B vaccine in healthy young adults
    • Halperin SA, Dobson S, McNeil S, et al.: Comparison of the safety and immunogenicity of hepatitis B virus surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide and a licensed hepatitis B vaccine in healthy young adults. Vaccine 2006;24:20-26.
    • (2006) Vaccine , vol.24 , pp. 20-26
    • Halperin, S.A.1    Dobson, S.2    McNeil, S.3
  • 21
    • 0037726807 scopus 로고    scopus 로고
    • A phase I study of the safety and immunogenicity of recombinant hepatitis B surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide adjuvant
    • Halperin SA, Van Nest G, Smith B, Simin A, Whiley H, and Eiden JJ: A phase I study of the safety and immunogenicity of recombinant hepatitis B surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide adjuvant. Vaccine 2003;21:2461-2467.
    • (2003) Vaccine , vol.21 , pp. 2461-2467
    • Halperin, S.A.1    Van Nest, G.2    Smith, B.3    Simin, A.4    Whiley, H.5    Eiden, J.J.6
  • 22
    • 0034237156 scopus 로고    scopus 로고
    • Improved mucosal protection against Venezuelan equine encephalitis virus is induced by the molecularly defined, live-attenuated V3526 vaccine candidate
    • Hart M, Caswell-Stephan K, Bakken R, et al.: Improved mucosal protection against Venezuelan equine encephalitis virus is induced by the molecularly defined, live-attenuated V3526 vaccine candidate. Vaccine 2000;18:3067-3075.
    • (2000) Vaccine , vol.18 , pp. 3067-3075
    • Hart, M.1    Caswell-Stephan, K.2    Bakken, R.3
  • 23
    • 0034237156 scopus 로고    scopus 로고
    • Improved mucosal protection against Venezuelan equine encephalitis virus is induced by the molecularly defined, live-attenuated V3526 vaccine candidate
    • Hart MK, Caswell-Stephan K, Bakken R, et al.: Improved mucosal protection against Venezuelan equine encephalitis virus is induced by the molecularly defined, live-attenuated V3526 vaccine candidate. Vaccine 2000;18:3067-3075.
    • (2000) Vaccine , vol.18 , pp. 3067-3075
    • Hart, M.K.1    Caswell-Stephan, K.2    Bakken, R.3
  • 24
    • 0035851360 scopus 로고    scopus 로고
    • Onset and duration of protective immunity to IA/IB and IE strains of Venezuelan equine encephalitis virus in vaccinated mice
    • Hart MK, Lind C, Bakken R, Robertson M, Tammariello R, and Ludwig GV: Onset and duration of protective immunity to IA/IB and IE strains of Venezuelan equine encephalitis virus in vaccinated mice. Vaccine 2001;20:616-622.
    • (2001) Vaccine , vol.20 , pp. 616-622
    • Hart, M.K.1    Lind, C.2    Bakken, R.3    Robertson, M.4    Tammariello, R.5    Ludwig, G.V.6
  • 25
    • 0034774473 scopus 로고    scopus 로고
    • Biological weapons - a primer for microbiologists
    • Hawley RJ, and Eitzen EM, Jr.: Biological weapons - a primer for microbiologists. Annu Rev Microbiol 2001;55:235-253.
    • (2001) Annu Rev Microbiol , vol.55 , pp. 235-253
    • Hawley, R.J.1    Eitzen Jr., E.M.2
  • 26
    • 26944468279 scopus 로고    scopus 로고
    • Intranasal immunisation with a 62 kDa proteinase combined with cholera toxin or CpG adjuvant protects against Trichomonas vaginalis genital tract infections in mice
    • Hernandez HM, Figueredo M, Garrido N, Sanchez L, and Sarracent J: Intranasal immunisation with a 62 kDa proteinase combined with cholera toxin or CpG adjuvant protects against Trichomonas vaginalis genital tract infections in mice. Int J Parasitol 2005;35:1333-1337.
    • (2005) Int J Parasitol , vol.35 , pp. 1333-1337
    • Hernandez, H.M.1    Figueredo, M.2    Garrido, N.3    Sanchez, L.4    Sarracent, J.5
  • 27
    • 0037135667 scopus 로고    scopus 로고
    • Overview: Cause and prevention in biowarfare and bioterrorism
    • Hilleman MR: Overview: cause and prevention in biowarfare and bioterrorism. Vaccine 2002;20:3055-3067.
    • (2002) Vaccine , vol.20 , pp. 3055-3067
    • Hilleman, M.R.1
  • 28
    • 0032567027 scopus 로고    scopus 로고
    • Immunostimulatory DNA is a potent mucosal adjuvant
    • Horner AA, Ronaghy A, Cheng PM, et al.: Immunostimulatory DNA is a potent mucosal adjuvant. Cell Immunol 1998;190:77-82.
    • (1998) Cell Immunol , vol.190 , pp. 77-82
    • Horner, A.A.1    Ronaghy, A.2    Cheng, P.M.3
  • 29
    • 0036570169 scopus 로고    scopus 로고
    • Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
    • Hornung V, Rothenfusser S, Britsch S, et al. Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J Immunol 2002;168:4531-4537.
    • (2002) J Immunol , vol.168 , pp. 4531-4537
    • Hornung, V.1    Rothenfusser, S.2    Britsch, S.3
  • 31
    • 0037311461 scopus 로고    scopus 로고
    • Cytotoxic T-cell activity is not detectable in Venezuelan equine encephalitis virus-infected mice
    • Jones LD, Bennett AM, Moss SR, Gould EA, and Phillpotts RJ: Cytotoxic T-cell activity is not detectable in Venezuelan equine encephalitis virus-infected mice. Virus Res 2003;91:255-259.
    • (2003) Virus Res , vol.91 , pp. 255-259
    • Jones, L.D.1    Bennett, A.M.2    Moss, S.R.3    Gould, E.A.4    Phillpotts, R.J.5
  • 32
    • 36348945135 scopus 로고    scopus 로고
    • Therapeutic applications of synthetic CpG oligodeoxynucleotides as TLR9 agonists for immune modulation
    • Jurk M, and Vollmer J: Therapeutic applications of synthetic CpG oligodeoxynucleotides as TLR9 agonists for immune modulation. BioDrugs 2007;21:387-401.
    • (2007) BioDrugs , vol.21 , pp. 387-401
    • Jurk, M.1    Vollmer, J.2
  • 33
    • 34548284487 scopus 로고    scopus 로고
    • Paradoxical enhancement of CD8 T cell-dependent anti-tumor protection despite reduced CD8 T cell responses with addition of a TLR9 agonist to a tumor vaccine
    • Karan D, Krieg AM, and Lubaroff DM: Paradoxical enhancement of CD8 T cell-dependent anti-tumor protection despite reduced CD8 T cell responses with addition of a TLR9 agonist to a tumor vaccine. Int J Cancer 2007;121:1520-1528.
    • (2007) Int J Cancer , vol.121 , pp. 1520-1528
    • Karan, D.1    Krieg, A.M.2    Lubaroff, D.M.3
  • 34
    • 0028533695 scopus 로고
    • The impact of developmental stage, route of administration and the immune-system on adenovirus-mediated gene-transfer
    • KassEisler A, FalckPedersen E, Elfenbein DH, Alvira M, Buttrick PM, and Leinwand LA: The impact of developmental stage, route of administration and the immune-system on adenovirus-mediated gene-transfer. Gene Ther 1994;1:395-402.
    • (1994) Gene Ther , vol.1 , pp. 395-402
    • KassEisler, A.1    FalckPedersen, E.2    Elfenbein, D.H.3    Alvira, M.4    Buttrick, P.M.5    Leinwand, L.A.6
  • 35
  • 36
    • 0035071566 scopus 로고    scopus 로고
    • Bioterrorism: Implications for the clinical microbiologist
    • Klietmann WF, and Ruoff KL: Bioterrorism: implications for the clinical microbiologist. Clin Microbiol Rev 2001;14:364-381.
    • (2001) Clin Microbiol Rev , vol.14 , pp. 364-381
    • Klietmann, W.F.1    Ruoff, K.L.2
  • 37
    • 0036219195 scopus 로고    scopus 로고
    • CpG motifs in bacterial DNA and their immune effects
    • Krieg AM: CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol 2002;20:709-760.
    • (2002) Annu Rev Immunol , vol.20 , pp. 709-760
    • Krieg, A.M.1
  • 38
    • 0028931102 scopus 로고
    • CpG motifs in bacterial DNA trigger direct B-cell activation
    • Krieg AM, Yi AK, Matson S, et al.: CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 1995;374:546-549.
    • (1995) Nature , vol.374 , pp. 546-549
    • Krieg, A.M.1    Yi, A.K.2    Matson, S.3
  • 39
    • 22544467274 scopus 로고    scopus 로고
    • Immunogenicity of heterologous prime-boost regimens involving recombinant adenovirus serotype 11 (Ad11) and Ad35 vaccine vectors in the presence of anti-Ad5 immunity
    • Lemckert AAC, Sumida SM, Holterman L, et al.: Immunogenicity of heterologous prime-boost regimens involving recombinant adenovirus serotype 11 (Ad11) and Ad35 vaccine vectors in the presence of anti-Ad5 immunity. J Virol 2005;79:9694-9701.
    • (2005) J Virol , vol.79 , pp. 9694-9701
    • Lemckert, A.A.C.1    Sumida, S.M.2    Holterman, L.3
  • 40
    • 33746978211 scopus 로고    scopus 로고
    • Decreased cytotoxic T cell activity generated by co-administration of PSA vaccine and CpG ODN is associated with increased tumor protection in a mouse model of prostate cancer
    • Lubaroff DM, Karan D, Andrews MP, et al.: Decreased cytotoxic T cell activity generated by co-administration of PSA vaccine and CpG ODN is associated with increased tumor protection in a mouse model of prostate cancer. Vaccine 2006;24:6155-6162.
    • (2006) Vaccine , vol.24 , pp. 6155-6162
    • Lubaroff, D.M.1    Karan, D.2    Andrews, M.P.3
  • 41
    • 33745487556 scopus 로고    scopus 로고
    • Toll-like receptors in cellular subsets of human tonsil T cells: Altered expression during recurrent tonsillitis
    • Mansson A, Adner M, and Cardell L: Toll-like receptors in cellular subsets of human tonsil T cells: altered expression during recurrent tonsillitis. Respir Res 2006;7:36.
    • (2006) Respir Res , vol.7 , pp. 36
    • Mansson, A.1    Adner, M.2    Cardell, L.3
  • 42
    • 0032876565 scopus 로고    scopus 로고
    • CpG DNA as mucosal adjuvant
    • McCluskie MJ, and Davis HL: CpG DNA as mucosal adjuvant. Vaccine 1999;18:231-237.
    • (1999) Vaccine , vol.18 , pp. 231-237
    • McCluskie, M.J.1    Davis, H.L.2
  • 43
    • 0031800888 scopus 로고    scopus 로고
    • CpG DNA, a novel immune enhancer for systemic and mucosal immunization with influenza virus
    • Moldoveanu Z, Love-Homan L, Huang WQ, and Krieg AM: CpG DNA, a novel immune enhancer for systemic and mucosal immunization with influenza virus. Vaccine 1998;16:1216-1224.
    • (1998) Vaccine , vol.16 , pp. 1216-1224
    • Moldoveanu, Z.1    Love-Homan, L.2    Huang, W.Q.3    Krieg, A.M.4
  • 44
    • 0027267426 scopus 로고
    • Immunogenicity of recombinant human adenovirus human-immunodeficiency-virus vaccines in chimpanzees
    • Natuk RJ, Lubeck MD, Chanda PK, et al.: Immunogenicity of recombinant human adenovirus human-immunodeficiency-virus vaccines in chimpanzees. AIDS Res Hum Retroviruses 1993;9:395-404.
    • (1993) AIDS Res Hum Retroviruses , vol.9 , pp. 395-404
    • Natuk, R.J.1    Lubeck, M.D.2    Chanda, P.K.3
  • 45
    • 34848874022 scopus 로고    scopus 로고
    • Alpha-beta T cells provide protection against lethal encephalitis in the murine model of VEEV infection
    • Paessler S, Yun NE, Judy BM, et al.: Alpha-beta T cells provide protection against lethal encephalitis in the murine model of VEEV infection. Virology 2007;367:307-323.
    • (2007) Virology , vol.367 , pp. 307-323
    • Paessler, S.1    Yun, N.E.2    Judy, B.M.3
  • 46
    • 33645236905 scopus 로고    scopus 로고
    • Boosting with an adenovirus-based vaccine improves protective efficacy against Venezuelan equine encephalitis virus following DNA vaccination
    • Perkins SD, O'Brien LM, and Phillpotts RJ: Boosting with an adenovirus-based vaccine improves protective efficacy against Venezuelan equine encephalitis virus following DNA vaccination. Vaccine 2006;24:3440-3445.
    • (2006) Vaccine , vol.24 , pp. 3440-3445
    • Perkins, S.D.1    O'Brien, L.M.2    Phillpotts, R.J.3
  • 47
    • 0031050547 scopus 로고    scopus 로고
    • A simple device for the exposure of animals to infectious microorganisms by the airborne route
    • Phillpotts RJ, Brooks TJ, and Cox CS: A simple device for the exposure of animals to infectious microorganisms by the airborne route. Epidemiol Infect 1997;118:71-75.
    • (1997) Epidemiol Infect , vol.118 , pp. 71-75
    • Phillpotts, R.J.1    Brooks, T.J.2    Cox, C.S.3
  • 48
    • 13444311692 scopus 로고    scopus 로고
    • Intranasal immunisation with defective adenovirus serotype 5 expressing the Venezuelan equine encephalitis virus E2 glycoprotein protects against airborne challenge with virulent virus
    • Phillpotts RJ, O'Brien L, Appleton RE, Carr S, and Bennett A: Intranasal immunisation with defective adenovirus serotype 5 expressing the Venezuelan equine encephalitis virus E2 glycoprotein protects against airborne challenge with virulent virus. Vaccine 2005;23:1615-1623.
    • (2005) Vaccine , vol.23 , pp. 1615-1623
    • Phillpotts, R.J.1    O'Brien, L.2    Appleton, R.E.3    Carr, S.4    Bennett, A.5
  • 49
    • 0033605098 scopus 로고    scopus 로고
    • TC-83 vaccine protects against airborne or subcutaneous challenge with heterologous mouse-virulent strains of Venezuelan equine encephalitis virus
    • Phillpotts RJ, Wright A. TC-83 vaccine protects against airborne or subcutaneous challenge with heterologous mouse-virulent strains of Venezuelan equine encephalitis virus. Vaccine 1999;17:982-988.
    • (1999) Vaccine , vol.17 , pp. 982-988
    • Phillpotts, R.J.1    Wright, A.2
  • 50
    • 34248548296 scopus 로고    scopus 로고
    • Toxicity assessment of Venezuelan equine encephalitis virus vaccine candidate strain v3526
    • Rao V, Hinz ME, Roberts BA, and Fine D: Toxicity assessment of Venezuelan equine encephalitis virus vaccine candidate strain v3526. Vaccine 2006;24:1710-1715.
    • (2006) Vaccine , vol.24 , pp. 1710-1715
    • Rao, V.1    Hinz, M.E.2    Roberts, B.A.3    Fine, D.4
  • 51
    • 17044362650 scopus 로고    scopus 로고
    • Genetically engineered, live, attenuated vaccines protect nonhuman primates against aerosol challenge with a virulent IE strain of Venezuelan equine encephalitis virus
    • Reed DS, Lind CM, Lackemeyer MG, Sullivan LJ, Pratt WD, and Parker MD: Genetically engineered, live, attenuated vaccines protect nonhuman primates against aerosol challenge with a virulent IE strain of Venezuelan equine encephalitis virus. Vaccine 2005;23:3139-3147.
    • (2005) Vaccine , vol.23 , pp. 3139-3147
    • Reed, D.S.1    Lind, C.M.2    Lackemeyer, M.G.3    Sullivan, L.J.4    Pratt, W.D.5    Parker, M.D.6
  • 52
    • 39549091293 scopus 로고    scopus 로고
    • Protection of mice by equine herpesvirus type 1-based experimental vaccine against lethal Venezuelan equine encephalitis virus infection in the absence of neutralizing antibodies
    • Rosas CT, Paessler S, Ni HL, and Osterrieder N: Protection of mice by equine herpesvirus type 1-based experimental vaccine against lethal Venezuelan equine encephalitis virus infection in the absence of neutralizing antibodies. Am J Trop Med Hyg 2008;78:83-92.
    • (2008) Am J Trop Med Hyg , vol.78 , pp. 83-92
    • Rosas, C.T.1    Paessler, S.2    Ni, H.L.3    Osterrieder, N.4
  • 53
    • 33644869748 scopus 로고    scopus 로고
    • CD8(+) T-cell tolerance can be broken by an adenoviral vaccine while CD4(+) T-cell tolerance is broken by additional co-administration of a toll-like receptor ligand
    • Salucci V, Mennuni C, Calvaruso F, et al.: CD8(+) T-cell tolerance can be broken by an adenoviral vaccine while CD4(+) T-cell tolerance is broken by additional co-administration of a toll-like receptor ligand. Scand J Immunol 2006;63:35-41.
    • (2006) Scand J Immunol , vol.63 , pp. 35-41
    • Salucci, V.1    Mennuni, C.2    Calvaruso, F.3
  • 54
    • 0020472347 scopus 로고
    • Non-neutralizing monoclonal-antibodies can prevent lethal alphavirus encephalitis
    • Schmaljohn AL, Johnson ED, Dalrymple JM, and Cole GA: Non-neutralizing monoclonal-antibodies can prevent lethal alphavirus encephalitis. Nature 1982;297:70-72.
    • (1982) Nature , vol.297 , pp. 70-72
    • Schmaljohn, A.L.1    Johnson, E.D.2    Dalrymple, J.M.3    Cole, G.A.4
  • 55
    • 1542299092 scopus 로고    scopus 로고
    • Recent advances in the development of HIV-1 vaccines using replication-incompetent adenovirus vectors
    • Shiver JW, and Emini EA: Recent advances in the development of HIV-1 vaccines using replication-incompetent adenovirus vectors. Ann Rev Med 2004;55:355-372.
    • (2004) Ann Rev Med , vol.55 , pp. 355-372
    • Shiver, J.W.1    Emini, E.A.2
  • 56
    • 14644390867 scopus 로고    scopus 로고
    • Rapid and strong human CD8(+) T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909
    • Speiser DE, Lienard D, Rufer N, et al.: Rapid and strong human CD8(+) T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909. J Clin Invest 2005;115:739-746.
    • (2005) J Clin Invest , vol.115 , pp. 739-746
    • Speiser, D.E.1    Lienard, D.2    Rufer, N.3
  • 57
    • 85054438797 scopus 로고
    • The problem of chemical and biological warfare
    • Stockholm International Peace Research Institute:, Almqvist and Wiksell, Stockholm
    • Stockholm International Peace Research Institute: The problem of chemical and biological warfare, Vol. 2. CB Weapons Today. Almqvist and Wiksell, Stockholm, 1973.
    • (1973) CB Weapons Today , vol.2
  • 58
    • 12144291467 scopus 로고    scopus 로고
    • Neutralizing antibodies and CD8(+) T lymphocytes both contribute to immunity to adenovirus serotype 5 vaccine vectors
    • Sumida SM, Truitt DM, Kishko MG, et al.: Neutralizing antibodies and CD8(+) T lymphocytes both contribute to immunity to adenovirus serotype 5 vaccine vectors. J Virol 2004;78:2666-2673.
    • (2004) J Virol , vol.78 , pp. 2666-2673
    • Sumida, S.M.1    Truitt, D.M.2    Kishko, M.G.3
  • 61
    • 41249091233 scopus 로고    scopus 로고
    • Protection of hamsters by Venezuelan equine encephalitis virus candidate vaccine V3526 against lethal challenge by mosquito bite and intraperitoneal injection
    • Turell MJ, and Parker MD: Protection of hamsters by Venezuelan equine encephalitis virus candidate vaccine V3526 against lethal challenge by mosquito bite and intraperitoneal injection. Am J Trop Med Hyg 2008;78:328-332.
    • (2008) Am J Trop Med Hyg , vol.78 , pp. 328-332
    • Turell, M.J.1    Parker, M.D.2
  • 62
    • 11144258882 scopus 로고    scopus 로고
    • Safety and immunogenicity of adenovirus-vectored nasal and epicutaneous influenza vaccines in humans
    • Van Kampen KR, Shi ZK, Gao P, et al.: Safety and immunogenicity of adenovirus-vectored nasal and epicutaneous influenza vaccines in humans. Vaccine 2005;23:1029-1036.
    • (2005) Vaccine , vol.23 , pp. 1029-1036
    • Van Kampen, K.R.1    Shi, Z.K.2    Gao, P.3
  • 63
    • 37549048034 scopus 로고    scopus 로고
    • Activation of tumor-specific CD8(+) T cells after intratumoral Ad5-TRAIL/CpG oligodeoxynucleotide combination therapy
    • VanOosten RL, and Griffith TS: Activation of tumor-specific CD8(+) T cells after intratumoral Ad5-TRAIL/CpG oligodeoxynucleotide combination therapy. Cancer Res 2007;67:11980-11990.
    • (2007) Cancer Res , vol.67 , pp. 11980-11990
    • VanOosten, R.L.1    Griffith, T.S.2
  • 64
    • 9144238063 scopus 로고    scopus 로고
    • Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities
    • Vollmer J, Weeratna R, Payette P, et al.: Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities. Eur J Immunol 2004;34:251-262.
    • (2004) Eur J Immunol , vol.34 , pp. 251-262
    • Vollmer, J.1    Weeratna, R.2    Payette, P.3
  • 66
    • 0033997899 scopus 로고    scopus 로고
    • CpG DNA induces stronger immune responses with less toxicity than other adjuvants
    • Weeratna RD, McCluskie MJ, Xu Y, and Davis HL: CpG DNA induces stronger immune responses with less toxicity than other adjuvants. Vaccine 2000;18:1755-1762.
    • (2000) Vaccine , vol.18 , pp. 1755-1762
    • Weeratna, R.D.1    McCluskie, M.J.2    Xu, Y.3    Davis, H.L.4
  • 67
    • 0031841501 scopus 로고    scopus 로고
    • Humane endpoints are an objective measure of morbidity in Venezuelan encephalomyelitis virus infection of mice
    • Wright AJ, and Phillpotts RJ: Humane endpoints are an objective measure of morbidity in Venezuelan encephalomyelitis virus infection of mice. Arch Virol 1998;143:1155-1162.
    • (1998) Arch Virol , vol.143 , pp. 1155-1162
    • Wright, A.J.1    Phillpotts, R.J.2
  • 68
    • 1842532903 scopus 로고    scopus 로고
    • Highly attenuated smallpox vaccine protects mice with and without immune deficiencies against pathogenic vaccinia virus challenge
    • Wyatt LS, Earl PL, Eller LA, and Moss B: Highly attenuated smallpox vaccine protects mice with and without immune deficiencies against pathogenic vaccinia virus challenge. Proc Natl Acad Sci USA 2004;101:4590-4595.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4590-4595
    • Wyatt, L.S.1    Earl, P.L.2    Eller, L.A.3    Moss, B.4
  • 69
    • 0141566356 scopus 로고    scopus 로고
    • Oral vaccination of mice with adenoviral vectors is not impaired by preexisting immunity to the vaccine carrier
    • Xiang ZQ, Gao GP, Reyes-Sandoval A, Li Y, Wilson JM, and Ertl HCJ: Oral vaccination of mice with adenoviral vectors is not impaired by preexisting immunity to the vaccine carrier. J Virol 2003;77:10780-10789.
    • (2003) J Virol , vol.77 , pp. 10780-10789
    • Xiang, Z.Q.1    Gao, G.P.2    Reyes-Sandoval, A.3    Li, Y.4    Wilson, J.M.5    Ertl, H.C.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.