The specific inhibitory effect of demethoxydehydroaltenusin, a derivative of dehydroaltenusin, on mammalian DNA polymerase α

International Journal of Molecular Medicine

Volumn 22, Issue 6, 2008, Pages 793-799

  Kuriyama, Isoko ^a   Fukudome, Keishi ^b   Kamisuki, Shinji ^b   Kuramochi, Kouji ^c   Tsubaki, Kazunori ^c   Sakaguchi, Kengo ^b   Sugawara, Fumio ^b   Yoshida, Hiromi ^a   Mizushina, Yoshiyuki ^a  

^a KOBE GAKUIN UNIVERSITY   (Japan)

^b TOKYO UNIVERSITY OF SCIENCE   (Japan)

^c KYOTO PREFECTURAL UNIVERSITY   (Japan)

Author keywords

Chemical knockout agent; Dehydroaltenusin; Demethoxydehydroaltenusin; DNA polymerase ; DNA replication; Enzyme inhibitor

Indexed keywords

ACETYLDEHYDROALTENUSIN; APHIDICOLIN; DEHYDROALTENUSIN; DEMETHOXYDEHYDROALTENUSIN; DNA DIRECTED DNA POLYMERASE ALPHA; DNA DIRECTED DNA POLYMERASE BETA; DNA DIRECTED DNA POLYMERASE GAMMA; DNA POLYMERASE ALPHA INHIBITOR; ENZYME INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; IC 50; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ACREMONIUM; ANIMALS; BENZOPYRANS; CATTLE; DNA POLYMERASE I; DNA-DIRECTED DNA POLYMERASE; DOSE-RESPONSE RELATIONSHIP, DRUG; FISHES; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; PLANTS; RATS;

EID: 58149245588     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm_00000087     Document Type: Article

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