Precise structural elucidation of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase α

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 20, 2004, Pages 5355-5359

  Kamisuki, Shinji ^a   Takahashi, Shunya ^b   Mizushina, Yoshiyuki ^c   Sakaguchi, Kengo ^a   Nakata, Tadashi ^a   Sugawara, Fumio ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

^b RIKEN   (Japan)

^c KOBE GAKUIN UNIVERSITY   (Japan)

Author keywords

Dehydroaltenusin; DNA polymerase ; Enzyme inhibitor; Tautomer

Indexed keywords

ACETIC ACID; ACETOACETIC ACID; DEHYDROALTENUSIN; DELTA LACTONE; DNA DIRECTED DNA POLYMERASE ALPHA; GAMMA LACTONE DERIVATIVE; LACTONE DERIVATIVE; PLANT EXTRACT; SOLVENT; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVITY; EQUILIBRIUM CONSTANT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY ANALYSIS; X RAY DIFFRACTION;

ACETYLATION; BENZOPYRANS; CRYSTALLOGRAPHY, X-RAY; DNA POLYMERASE I; SOLVENTS;

MAMMALIA;

EID: 4544252452     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.07.047     Document Type: Article

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