메뉴 건너뛰기




Volumn 13, Issue 12, 2008, Pages 3198-3223

Gastric and duodenal antiulcer activity of alkaloids: A review

Author keywords

Alkaloids; Antiulcer activity; Peptic ulcer; Review

Indexed keywords

ALKALOID; ANTIULCER AGENT;

EID: 58149234165     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules13123198     Document Type: Review
Times cited : (118)

References (84)
  • 2
    • 25644437787 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of gastrointestinal ulcer healing
    • Tarnawski, A.S. Cellular and molecular mechanisms of gastrointestinal ulcer healing. Digest. Dis. Sci. 2005, 50, 24-33.
    • (2005) Digest. Dis. Sci , vol.50 , pp. 24-33
    • Tarnawski, A.S.1
  • 3
    • 0029953816 scopus 로고    scopus 로고
    • The cellular and molecular basis of gastric mucosal defense
    • Wallace, J.L.; Granger, D.N. The cellular and molecular basis of gastric mucosal defense. FASEB J. 1996, 10, 731-740.
    • (1996) FASEB J , vol.10 , pp. 731-740
    • Wallace, J.L.1    Granger, D.N.2
  • 4
    • 7444231626 scopus 로고    scopus 로고
    • Gastroduodenal mucosal defense: Role of endogenous mediators
    • Kaunitz, J.D.; Akiba, Y. Gastroduodenal mucosal defense: role of endogenous mediators. Curr. Opin. Gastroenterol. 2004, 20, 526-532.
    • (2004) Curr. Opin. Gastroenterol , vol.20 , pp. 526-532
    • Kaunitz, J.D.1    Akiba, Y.2
  • 5
    • 0035468914 scopus 로고    scopus 로고
    • Gastric toxicity and mucosal ulceration induced by oxygen-derived reactive species: Protection by melatonin
    • Bandyopadhyay, D.; Biswas, K.; Bhattacharyya, M.; Reiter, R.J.; Banerjee, R.K. Gastric toxicity and mucosal ulceration induced by oxygen-derived reactive species: protection by melatonin. Curr. Mol. Med. 2001, 1, 501-513.
    • (2001) Curr. Mol. Med , vol.1 , pp. 501-513
    • Bandyopadhyay, D.1    Biswas, K.2    Bhattacharyya, M.3    Reiter, R.J.4    Banerjee, R.K.5
  • 6
    • 84907781931 scopus 로고    scopus 로고
    • Estratégias para obtenção de compostos farmacologicamente ativos a partir de plantas medicinais: Conceitos sobre modificação estrutural para otimização da atividade.
    • Cechinel Filho, V.; Yunes, R.A. Estratégias para obtenção de compostos farmacologicamente ativos a partir de plantas medicinais: conceitos sobre modificação estrutural para otimização da atividade. Quim. Nova 1998, 21, 99-105.
    • (1998) Quim. Nova , vol.21 , pp. 99-105
    • Cechinel Filho, V.1    Yunes, R.A.2
  • 7
    • 0342334603 scopus 로고
    • Busca racional de princípios ativos em plantas.
    • Kaplan, M.A.C.; Gottlieb, O.R. Busca racional de princípios ativos em plantas. Interciência 1990, 15, 26-29.
    • (1990) Interciência , vol.15 , pp. 26-29
    • Kaplan, M.A.C.1    Gottlieb, O.R.2
  • 8
    • 0029946017 scopus 로고    scopus 로고
    • Medicinal plant genetic resources and international cooperation: The Brazilian perspective
    • Elisabetsky, E.; Costa-Campos, L. Medicinal plant genetic resources and international cooperation: the Brazilian perspective. J. Ethnopharmacol. 1996, 51, 111-119.
    • (1996) J. Ethnopharmacol , vol.51 , pp. 111-119
    • Elisabetsky, E.1    Costa-Campos, L.2
  • 9
    • 0003984159 scopus 로고
    • Produtos naturais: Alternativa segura?
    • Secco, R.S. Produtos naturais: alternativa segura? Cienc. Cult. 1990, 42, 807-810.
    • (1990) Cienc. Cult , vol.42 , pp. 807-810
    • Secco, R.S.1
  • 10
    • 44949127129 scopus 로고    scopus 로고
    • Alkaloid biosynthesis: Metabolism and trafficking
    • Ziegler, J.; Facchini, P.J. Alkaloid biosynthesis: metabolism and trafficking. Annu. Rev. Plant Biol. 2008, 59, 735-769.
    • (2008) Annu. Rev. Plant Biol , vol.59 , pp. 735-769
    • Ziegler, J.1    Facchini, P.J.2
  • 11
    • 58149244297 scopus 로고    scopus 로고
    • Henriques, A.T.; Limberger, R.P.; Kerber, V.A.; Moreno, P.R.H. In: Farmacognosia: da planta ao medicamento, 5 ed.; Simões, C. M. O. et al., Eds. Editoras of the Universidades Federais de Santa Catarina and Rio Grande do Sul: Porto Alegre/Florianópolis, Brazil, 2004; Chapter 29, pp. 765-792.
    • Henriques, A.T.; Limberger, R.P.; Kerber, V.A.; Moreno, P.R.H. In: Farmacognosia: da planta ao medicamento, 5 ed.; Simões, C. M. O. et al., Eds. Editoras of the Universidades Federais de Santa Catarina and Rio Grande do Sul: Porto Alegre/Florianópolis, Brazil, 2004; Chapter 29, pp. 765-792.
  • 17
  • 18
    • 34047126687 scopus 로고    scopus 로고
    • Plants and bioactive compounds for the treatment of Parkinson's disease
    • Morais, L.C.S.L.; Barbosa-Filho, J.M.; Almeida, R.N. Plants and bioactive compounds for the treatment of Parkinson's disease. Arq. Fitomed. 2003, 1, 127-132.
    • (2003) Arq. Fitomed , vol.1 , pp. 127-132
    • Morais, L.C.S.L.1    Barbosa-Filho, J.M.2    Almeida, R.N.3
  • 28
    • 0027314119 scopus 로고
    • Effect of khatamines and their enantiomers on aspirin, indomethacin, phenylbutazone and reserpine induced gastric ulcers in rats
    • Al-Shabanah, O.A.; Islam, M.W.; Al-Gharably, N.M.; Al-Harbi, M.M. Effect of khatamines and their enantiomers on aspirin, indomethacin, phenylbutazone and reserpine induced gastric ulcers in rats. Res Commun. Subst. Abuse 1993, 14, 81-94.
    • (1993) Res Commun. Subst. Abuse , vol.14 , pp. 81-94
    • Al-Shabanah, O.A.1    Islam, M.W.2    Al-Gharably, N.M.3    Al-Harbi, M.M.4
  • 29
    • 0017644906 scopus 로고
    • Analysis of the mechanism of the protective activity of some sympathomimetic amines in experimental ulcers
    • Sandor, V.; Cuparencu, B. Analysis of the mechanism of the protective activity of some sympathomimetic amines in experimental ulcers. Pharmacology 1977, 15, 208-217.
    • (1977) Pharmacology , vol.15 , pp. 208-217
    • Sandor, V.1    Cuparencu, B.2
  • 30
    • 0031419062 scopus 로고    scopus 로고
    • Gastric mucous membrane-protective principles of Coptidis rhizoma
    • Hirano, H.; Tokuhira, T.; Yokoi, T.; Shingu, T. Gastric mucous membrane-protective principles of Coptidis rhizoma. Nat. Med. 1997, 51, 516-518.
    • (1997) Nat. Med , vol.51 , pp. 516-518
    • Hirano, H.1    Tokuhira, T.2    Yokoi, T.3    Shingu, T.4
  • 31
    • 0017043420 scopus 로고
    • Behavioral pharmacology of berberine-type alkaloids. (1). Central depressive action of Coptidis rhizoma and its constituents
    • Yamahara, J. Behavioral pharmacology of berberine-type alkaloids. (1). Central depressive action of Coptidis rhizoma and its constituents. Nippon Yakurigaku Zasshi 1976, 72, 899-908.
    • (1976) Nippon Yakurigaku Zasshi , vol.72 , pp. 899-908
    • Yamahara, J.1
  • 33
    • 0033858597 scopus 로고    scopus 로고
    • Prophylactic and healing properties of a new anti-ulcer compound from Enantia chlorantha in rats
    • Tan, P.V.; Nyasse, B.; Enow-Orock, G.E.; Wafo, P.; Forcha, E.A. Prophylactic and healing properties of a new anti-ulcer compound from Enantia chlorantha in rats. Phytomedicine 2000, 7, 291-296.
    • (2000) Phytomedicine , vol.7 , pp. 291-296
    • Tan, P.V.1    Nyasse, B.2    Enow-Orock, G.E.3    Wafo, P.4    Forcha, E.A.5
  • 34
    • 0036087159 scopus 로고    scopus 로고
    • Synergistic and potentiating effects of ranitidine and two new anti-ulcer compounds from Enantia chlorantha and Voacanga africana in experimental animal models
    • Tan, P.V.; Nyasse, B.; Dimo, T.; Wafo, P.; Akahkuh, B.T. Synergistic and potentiating effects of ranitidine and two new anti-ulcer compounds from Enantia chlorantha and Voacanga africana in experimental animal models. Pharmazie 2002, 57, 409-412.
    • (2002) Pharmazie , vol.57 , pp. 409-412
    • Tan, P.V.1    Nyasse, B.2    Dimo, T.3    Wafo, P.4    Akahkuh, B.T.5
  • 35
    • 0033667267 scopus 로고    scopus 로고
    • Analysis of gastric mucosus membrane-protective compounds in Coptidis rhizoma
    • Hirano, H.; Tokuhira, T.; Yoshioka, Y.; Yokoi, T.; Shingu, T. Analysis of gastric mucosus membrane-protective compounds in Coptidis rhizoma. Nat. Med. 2000, 54, 209-212.
    • (2000) Nat. Med , vol.54 , pp. 209-212
    • Hirano, H.1    Tokuhira, T.2    Yoshioka, Y.3    Yokoi, T.4    Shingu, T.5
  • 36
    • 0035172930 scopus 로고    scopus 로고
    • Gastric-mucous membrane protection activity of coptisine derivatives
    • Hirano, H.; Osawa, E.; Yamaoka, Y.; Yokoi, T. Gastric-mucous membrane protection activity of coptisine derivatives. Biol. Pharm. Bull. 2001, 24, 1277-1281.
    • (2001) Biol. Pharm. Bull , vol.24 , pp. 1277-1281
    • Hirano, H.1    Osawa, E.2    Yamaoka, Y.3    Yokoi, T.4
  • 37
    • 0029155763 scopus 로고
    • Effects of TDEYA from Atractylodes rhizome on experimental gastric ulcer
    • Sakurai, T.; Sugawara, H.; Saito, K.I.; Kano, Y. Effects of TDEYA from Atractylodes rhizome on experimental gastric ulcer. Phytother. Res. 1995, 9, 340-345.
    • (1995) Phytother. Res , vol.9 , pp. 340-345
    • Sakurai, T.1    Sugawara, H.2    Saito, K.I.3    Kano, Y.4
  • 38
    • 0020580046 scopus 로고
    • Studies of crude drugs about its origin, process and quality. I. The preventive effects of chinese crude drug "zhu" on experimental stomach ulcer an its pharmacological evaluation (1)
    • Kubo, M.; Nogami, M.; Nishimura, M.; Moriura, T.; Arichi, S. Studies of crude drugs about its origin, process and quality. I. The preventive effects of chinese crude drug "zhu" on experimental stomach ulcer an its pharmacological evaluation (1). Yakugaku Zasshi 1983, 103, 442-448.
    • (1983) Yakugaku Zasshi , vol.103 , pp. 442-448
    • Kubo, M.1    Nogami, M.2    Nishimura, M.3    Moriura, T.4    Arichi, S.5
  • 40
    • 0016609731 scopus 로고
    • Duodenal ulcers produced in rats by propionitrile. Factors inhibiting and aggravating such ulcers
    • Robert, A.; Nezamis, J. E.; Lancaster, C. Duodenal ulcers produced in rats by propionitrile. Factors inhibiting and aggravating such ulcers. Toxicol. Appl. Pharmacol. 1975, 31, 201-207.
    • (1975) Toxicol. Appl. Pharmacol , vol.31 , pp. 201-207
    • Robert, A.1    Nezamis, J.E.2    Lancaster, C.3
  • 41
    • 15144347048 scopus 로고
    • Effect of anisodamine on gastric ulcer induced by restraint water-immersion in rats
    • Wan, Y.J. Effect of anisodamine on gastric ulcer induced by restraint water-immersion in rats. Clin. Gastroenterol. 1993, 3, 154-158.
    • (1993) Clin. Gastroenterol , vol.3 , pp. 154-158
    • Wan, Y.J.1
  • 42
    • 58149248485 scopus 로고    scopus 로고
    • Effect of anisodamine on the reserpine-induced gastric mucosal lesion in rats
    • Wang, J.L. Effect of anisodamine on the reserpine-induced gastric mucosal lesion in rats. Zhongguo Bingli Shengli Zazhi 2000, 16, 237-242.
    • (2000) Zhongguo Bingli Shengli Zazhi , vol.16 , pp. 237-242
    • Wang, J.L.1
  • 44
    • 0029034770 scopus 로고
    • Topical nicotine protects rat gastric mucosa against ASA-induced damage. A role for mucosal fluid secretion in cytoprotection
    • Fallone, C.A.; Morris, G.P. Topical nicotine protects rat gastric mucosa against ASA-induced damage. A role for mucosal fluid secretion in cytoprotection. Digest. Dis. Sci. 1995, 40, 936-942.
    • (1995) Digest. Dis. Sci , vol.40 , pp. 936-942
    • Fallone, C.A.1    Morris, G.P.2
  • 45
    • 0021257839 scopus 로고
    • Protective effects of matrine and oxymatrine on stress ulcer in relation to their effects on the central nervous system
    • Yamazaki, M.; Arai, A.; Suzuki, S.; Takeuchi, T. Protective effects of matrine and oxymatrine on stress ulcer in relation to their effects on the central nervous system. Yakugaku Zasshi 1984, 104, 293-301.
    • (1984) Yakugaku Zasshi , vol.104 , pp. 293-301
    • Yamazaki, M.1    Arai, A.2    Suzuki, S.3    Takeuchi, T.4
  • 46
    • 0007629261 scopus 로고
    • Application of experimental stress ulcer test in mice for the survey of neurotropic naturally occurring drug materials
    • Yamazaki, M.; Shirota, H. Application of experimental stress ulcer test in mice for the survey of neurotropic naturally occurring drug materials. Shoyakugaku Zasshi 1981, 35, 96-102.
    • (1981) Shoyakugaku Zasshi , vol.35 , pp. 96-102
    • Yamazaki, M.1    Shirota, H.2
  • 47
    • 58149224888 scopus 로고
    • Antiulcerogenic activity of oxymatrine
    • s-51
    • Yamazaki, M.; Arai, A. Antiulcerogenic activity of oxymatrine. J. Pharmacobiodyn. 1985, 8, s-51.
    • (1985) J. Pharmacobiodyn , vol.8
    • Yamazaki, M.1    Arai, A.2
  • 49
    • 0033623623 scopus 로고    scopus 로고
    • The pharmacological studies on matrine and oxymatrine
    • Yamazaki, M. The pharmacological studies on matrine and oxymatrine. Yakugaku Zasshi 2000, 120, 1025-1033.
    • (2000) Yakugaku Zasshi , vol.120 , pp. 1025-1033
    • Yamazaki, M.1
  • 50
    • 0025175453 scopus 로고
    • Effects of Trikatu and its individual components and piperine on gastrointestinal tract: Trikatu - a bioavailable enhancer
    • Annamalai, A.R.; Manavalan, R. Effects of Trikatu and its individual components and piperine on gastrointestinal tract: Trikatu - a bioavailable enhancer. Indian Drugs 1990, 27, 595-604.
    • (1990) Indian Drugs , vol.27 , pp. 595-604
    • Annamalai, A.R.1    Manavalan, R.2
  • 51
    • 0034052098 scopus 로고    scopus 로고
    • Protective action of piperine against experimental gastric ulcer
    • Bai, Y.F.; Xu, H. Protective action of piperine against experimental gastric ulcer. Acta Pharmacol. Sin. 2000, 21, 357-359.
    • (2000) Acta Pharmacol. Sin , vol.21 , pp. 357-359
    • Bai, Y.F.1    Xu, H.2
  • 53
    • 0034634270 scopus 로고    scopus 로고
    • Capsaicin protects against ethanol-induced oxidative injury in the gastric mucosa of rats
    • Park, J.S.; Choi, M.A.; Kim, B.S.; Han, I.S.; Kurata, T.; Yu, R. Capsaicin protects against ethanol-induced oxidative injury in the gastric mucosa of rats. Life Sci. 2000, 67, 3087-3093.
    • (2000) Life Sci , vol.67 , pp. 3087-3093
    • Park, J.S.1    Choi, M.A.2    Kim, B.S.3    Han, I.S.4    Kurata, T.5    Yu, R.6
  • 54
    • 0022611436 scopus 로고
    • Anti-ulcer effect of steroidal alkaloids extracted from Pachysandra terminalis
    • Watanabe, H.; Watanabe, K.; Shimadzu, M.; Kikuchi, T.; Liu, Z. Anti-ulcer effect of steroidal alkaloids extracted from Pachysandra terminalis. Planta Med. 1986, 52, 56-58.
    • (1986) Planta Med , vol.52 , pp. 56-58
    • Watanabe, H.1    Watanabe, K.2    Shimadzu, M.3    Kikuchi, T.4    Liu, Z.5
  • 55
    • 0030934632 scopus 로고    scopus 로고
    • Melatonin affords protection against gastric lesions induced by ischemia-reperfusion possibly due to its antioxidant and mucosal microcirculatory effects
    • Konturek, P.C.; Konturek, S.J.; Majka, J.; Zembala, M.; Hahn, E.G. Melatonin affords protection against gastric lesions induced by ischemia-reperfusion possibly due to its antioxidant and mucosal microcirculatory effects. Eur. J. Pharmacol. 1997, 322, 73-77.
    • (1997) Eur. J. Pharmacol , vol.322 , pp. 73-77
    • Konturek, P.C.1    Konturek, S.J.2    Majka, J.3    Zembala, M.4    Hahn, E.G.5
  • 56
    • 0024349220 scopus 로고
    • Pharmacological studies of indole alkaloids obtained from domestic plants Uncaria rhynchophylla Miq. and Amsonia elliptica Roem. et Schult
    • Ozaki, Y. Pharmacological studies of indole alkaloids obtained from domestic plants Uncaria rhynchophylla Miq. and Amsonia elliptica Roem. et Schult. Nippon Yakurigaku Zasshi 1989, 94, 17-26.
    • (1989) Nippon Yakurigaku Zasshi , vol.94 , pp. 17-26
    • Ozaki, Y.1
  • 57
    • 58149245573 scopus 로고    scopus 로고
    • Omoto, T, Shinho, Y, Nakajima, K, Ishiwatari, H, Ito, H. Antiulcer alkaloids from Picrasma ailanthus. Jpn Kokai Tokkyo Koho 02004790, 1990
    • Omoto, T.; Shinho, Y.; Nakajima, K.; Ishiwatari, H.; Ito, H. Antiulcer alkaloids from Picrasma ailanthus. Jpn Kokai Tokkyo Koho 02004790, 1990.
  • 58
    • 0028145276 scopus 로고
    • Studies on the gastric antiulcer components from the woods of Picrasma quassioides (Simaroubaceae)
    • Niiho, Y.; Mitsunaga, K.; Koike, K.; Ohmoto, T. Studies on the gastric antiulcer components from the woods of Picrasma quassioides (Simaroubaceae). Nat. Med. 1994, 48, 116-121.
    • (1994) Nat. Med , vol.48 , pp. 116-121
    • Niiho, Y.1    Mitsunaga, K.2    Koike, K.3    Ohmoto, T.4
  • 60
    • 7044272244 scopus 로고    scopus 로고
    • Preventive activity of pyrrolizidine alkaloids from Senecio brasiliensis (Asteraceae) on gastric and duodenal induced ulcer on mice and rats
    • Toma, W.; Trigo, J.R.; Bensuaski de Paula, A.C.; Souza Brito, A.R.M. Preventive activity of pyrrolizidine alkaloids from Senecio brasiliensis (Asteraceae) on gastric and duodenal induced ulcer on mice and rats. J. Ethnopharmacol. 2004, 95, 345-351.
    • (2004) J. Ethnopharmacol , vol.95 , pp. 345-351
    • Toma, W.1    Trigo, J.R.2    Bensuaski de Paula, A.C.3    Souza Brito, A.R.M.4
  • 61
    • 58149226143 scopus 로고
    • Cicotti, I. Pharmaceutical composition for treating gastro-duodenal ulcers
    • GB 2054373
    • Cicotti, I. Pharmaceutical composition for treating gastro-duodenal ulcers. GB 2054373, 1981.
    • (1981)
  • 62
    • 0019443081 scopus 로고
    • Study on the preparation of an "instant" type product (Ulcovex) for gastric and duodenal ulcers. Part I. Chemical study of Calendulae flores product preparation of the "instant" type extract and determination of the control methodology
    • Istudor, V.; Mantoiu, M.; Badescu, I. Study on the preparation of an "instant" type product (Ulcovex) for gastric and duodenal ulcers. Part I. Chemical study of Calendulae flores product preparation of the "instant" type extract and determination of the control methodology. Farmacia (Bucharest), 1981, 29, 41-48.
    • (1981) Farmacia (Bucharest) , vol.29 , pp. 41-48
    • Istudor, V.1    Mantoiu, M.2    Badescu, I.3
  • 63
    • 0021702210 scopus 로고
    • Pharmacological actions of analogues of feruloylhistamine, an imidazole alkaloid of Ephedra roots
    • Hikino, H.; Kiso, Y.; Ogata, M.; Konno, C.; Aisaka, K.; Kubota, H.; Hirose, N.; Ishihara, T. Pharmacological actions of analogues of feruloylhistamine, an imidazole alkaloid of Ephedra roots. Planta Med. 1984, 50, 478-480.
    • (1984) Planta Med , vol.50 , pp. 478-480
    • Hikino, H.1    Kiso, Y.2    Ogata, M.3    Konno, C.4    Aisaka, K.5    Kubota, H.6    Hirose, N.7    Ishihara, T.8
  • 64
    • 0016730344 scopus 로고
    • Study of the effects of curcumin on 5-HT induced gastric lesions in guinea pigs
    • Sinha, M.; Sikdar, S.; Dasgupta, S.R. Study of the effects of curcumin on 5-HT induced gastric lesions in guinea pigs. Indian Med. Gaz. 1975, 15, 318.
    • (1975) Indian Med. Gaz , vol.15 , pp. 318
    • Sinha, M.1    Sikdar, S.2    Dasgupta, S.R.3
  • 65
    • 58149245572 scopus 로고    scopus 로고
    • Machova, J, Nosalova, V, Babulova, A. Pharmaceuticals for stomach ulcer treatment. Czech Patent 274070, 1992
    • Machova, J.; Nosalova, V.; Babulova, A. Pharmaceuticals for stomach ulcer treatment. Czech Patent 274070, 1992.
  • 66
    • 0026468387 scopus 로고
    • Effect of cathinone, an active constituent of khat (Catha edulis Forsk) and amphetamine on experimental gastric ulcer and secretions
    • Al-Shabanah, O.A.; Al-Gharably, N.A.; Islam, M.W.; Al-Harbi, M.M. Effect of cathinone, an active constituent of khat (Catha edulis Forsk) and amphetamine on experimental gastric ulcer and secretions. Med. Sci. Res. 1992, 20, 817-819.
    • (1992) Med. Sci. Res , vol.20 , pp. 817-819
    • Al-Shabanah, O.A.1    Al-Gharably, N.A.2    Islam, M.W.3    Al-Harbi, M.M.4
  • 67
    • 58149276496 scopus 로고    scopus 로고
    • Iwasa, J.; Naruto, S.; Ikeda, N.; Sohji, Y. Salt of dehydrocorydaline. Can. Pat. CA 934547, 1974.
    • Iwasa, J.; Naruto, S.; Ikeda, N.; Sohji, Y. Salt of dehydrocorydaline. Can. Pat. CA 934547, 1974.
  • 68
    • 0016224757 scopus 로고
    • Mode of action of dehydrocorydaline on gastric acid secretion in rats
    • Watanabe, K.; Goto, Y.; Murakami, M. Mode of action of dehydrocorydaline on gastric acid secretion in rats. Oyo Yakuri 1974, 8, 1105.
    • (1974) Oyo Yakuri , vol.8 , pp. 1105
    • Watanabe, K.1    Goto, Y.2    Murakami, M.3
  • 69
    • 0016270718 scopus 로고
    • Effect of dehydrocorydaline chloride on experimental gastric and duodenal ulcers
    • Sohji, Y.; Kawashima, K.; Shimizu, M. Effect of dehydrocorydaline chloride on experimental gastric and duodenal ulcers. Nippon Yakurigaku Zasshi 1974, 70, 425-437.
    • (1974) Nippon Yakurigaku Zasshi , vol.70 , pp. 425-437
    • Sohji, Y.1    Kawashima, K.2    Shimizu, M.3
  • 70
    • 58149226141 scopus 로고
    • Corydamine and tetrahydrocorydamine derivatives.
    • Jpn. Kokai Tokkyo Koho 49125399
    • Nishioka, I.; Takao, N.; Nonaka, G.; Iwasa, K. Corydamine and tetrahydrocorydamine derivatives. Jpn. Kokai Tokkyo Koho 49125399, 1974.
    • (1974)
    • Nishioka, I.1    Takao, N.2    Nonaka, G.3    Iwasa, K.4
  • 72
    • 0018212216 scopus 로고
    • Comparative study of two anti-ulcerogenic drugs-glaziovine and sulpiride
    • Chaumontet, M.; Capt, M.; Gold-Aubert, P. Comparative study of two anti-ulcerogenic drugs-glaziovine and sulpiride. Arzneimittelforsch. 1978, 28, 2119-2121.
    • (1978) Arzneimittelforsch , vol.28 , pp. 2119-2121
    • Chaumontet, M.1    Capt, M.2    Gold-Aubert, P.3
  • 73
    • 0019521768 scopus 로고
    • Glaziovine as antiulcer: A double-blind short-term controlled clinical trial in comparison with cimetidine
    • Galeone, M.; Cacioli, D.; Moise, G.; Gherardi, G.; Quadro, G. Glaziovine as antiulcer: a double-blind short-term controlled clinical trial in comparison with cimetidine. Curr. Ther. Res. 1981, 30, 44-49.
    • (1981) Curr. Ther. Res , vol.30 , pp. 44-49
    • Galeone, M.1    Cacioli, D.2    Moise, G.3    Gherardi, G.4    Quadro, G.5
  • 74
    • 0016123483 scopus 로고
    • Effects of several mild antiulcer agents on pylorus ligated rats (shay rats)
    • Ishii, Y.; Fujii, Y. Effects of several mild antiulcer agents on pylorus ligated rats (shay rats). Nippon Yakurigaku Zasshi 1974, 70, 863.
    • (1974) Nippon Yakurigaku Zasshi , vol.70 , pp. 863
    • Ishii, Y.1    Fujii, Y.2
  • 75
    • 0029069908 scopus 로고
    • Effect of capsaicin and chilli on ethanol induced gastric mucosal injury in the rat
    • Kang, J.Y.; Teng, C.H.; Wee, A.; Chen, F.C. Effect of capsaicin and chilli on ethanol induced gastric mucosal injury in the rat. Gut 1995, 36, 664-669.
    • (1995) Gut , vol.36 , pp. 664-669
    • Kang, J.Y.1    Teng, C.H.2    Wee, A.3    Chen, F.C.4
  • 76
    • 0029051719 scopus 로고
    • Capsaicin and its analogue resiniferatoxin inhibit gastric acid secretion in pylorus-ligated rats
    • Abdel Salam, O.M.E.; Szolcsanyi, J.; Mozsik, G. Capsaicin and its analogue resiniferatoxin inhibit gastric acid secretion in pylorus-ligated rats. Pharmacol. Res. 1995, 31, 341-345.
    • (1995) Pharmacol. Res , vol.31 , pp. 341-345
    • Abdel Salam, O.M.E.1    Szolcsanyi, J.2    Mozsik, G.3
  • 77
    • 0029565909 scopus 로고
    • Studies on the effect of intragastric capsaicin on gastric ulcer and on the prostacyclin-induced cytoprotection in rats
    • Abdel Salam, O.M.E.; Mozsik, G.; Szolcsanyi, J. Studies on the effect of intragastric capsaicin on gastric ulcer and on the prostacyclin-induced cytoprotection in rats. Pharmacol. Res. 1995, 32, 209-215.
    • (1995) Pharmacol. Res , vol.32 , pp. 209-215
    • Abdel Salam, O.M.E.1    Mozsik, G.2    Szolcsanyi, J.3
  • 78
    • 0030054956 scopus 로고    scopus 로고
    • Effect of capsaicin and cimetidine on the healing of acetic acid induced gastric ulceration in the rat
    • Kang, J.Y.; Teng, C.H.; Chen, F.C. Effect of capsaicin and cimetidine on the healing of acetic acid induced gastric ulceration in the rat. Gut 1996, 38, 832-836.
    • (1996) Gut , vol.38 , pp. 832-836
    • Kang, J.Y.1    Teng, C.H.2    Chen, F.C.3
  • 79
    • 58149248484 scopus 로고    scopus 로고
    • Effect of tetramethylpyrazine on gastric ulcer induced by restraint/water-immersion stress in rats
    • Wan, J.L.; Wang, C.; Cui, S.Z. Effect of tetramethylpyrazine on gastric ulcer induced by restraint/water-immersion stress in rats. Chung Ts'ao Yao 2000, 31, 115-117.
    • (2000) Chung Ts'ao Yao , vol.31 , pp. 115-117
    • Wan, J.L.1    Wang, C.2    Cui, S.Z.3
  • 80
    • 0018249349 scopus 로고
    • Biologically active principles of crude drugs: Pharmacological actions of Swertia japonica extracts, swertiamarin and gentianine
    • Yamahara, J.; Konoshima, T.; Sawada, T.; Fujimura, H. Biologically active principles of crude drugs: pharmacological actions of Swertia japonica extracts, swertiamarin and gentianine. Yakugaku Zasshi 1978, 98, 1446-1451.
    • (1978) Yakugaku Zasshi , vol.98 , pp. 1446-1451
    • Yamahara, J.1    Konoshima, T.2    Sawada, T.3    Fujimura, H.4
  • 81
    • 0017887066 scopus 로고
    • Mallorepine, cyano-gamma-pyridone from Mallotus repandus
    • Hikino, H.; Tamada, M.; Yen, K.Y. Mallorepine, cyano-gamma-pyridone from Mallotus repandus. Planta Med. 1978, 33, 385-388.
    • (1978) Planta Med , vol.33 , pp. 385-388
    • Hikino, H.1    Tamada, M.2    Yen, K.Y.3
  • 83
    • 58149276498 scopus 로고
    • Synthesis and biological activity of tropine alkaloids quaternary derivatives I. Tropine derivatives
    • Gorecki, P.; Drozdzynska, M.; Kedzia, B.; Przybylska, D. Synthesis and biological activity of tropine alkaloids quaternary derivatives I. Tropine derivatives. Herba Pol. 1983, 29, 135-149.
    • (1983) Herba Pol , vol.29 , pp. 135-149
    • Gorecki, P.1    Drozdzynska, M.2    Kedzia, B.3    Przybylska, D.4
  • 84
    • 58149222261 scopus 로고
    • Study of antisecretory effect of oxymatrine, a constituent of Sophora flavescens
    • s-55
    • Arai, A.; Yamazaki, M. Study of antisecretory effect of oxymatrine, a constituent of Sophora flavescens. J. Pharmacobiodyn. 1987, 10, s-55.
    • (1987) J. Pharmacobiodyn , vol.10
    • Arai, A.1    Yamazaki, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.