-
1
-
-
0034612175
-
Inflammation and Alzheimer's disease
-
Akiyama H., Barger S., Barnum S., Bradt B., Bauer J., Cole G.M., Cooper N.R., Eikelenboom P., Emmerling M., Fiebich B.L., Finch C.E., Frautschy S., Griffin W.S., Hampel H., Hull M., Landreth G., Lue L., Mrak R., Mackenzie I.R., McGeer P.L., O'Banion M.K., Pachter J., Pasinetti G., Plata-Salaman C., Rogers J., Rydel R., Shen Y., Streit W., Strohmeyer R., Tooyoma I., Van Muiswinkel F.L., Veerhuis R., Walker D., Webster S., Wegrzyniak B., Wenk G., and Wyss-Coray T. Inflammation and Alzheimer's disease. Neurobiol. Aging 21 (2000) 383-421
-
(2000)
Neurobiol. Aging
, vol.21
, pp. 383-421
-
-
Akiyama, H.1
Barger, S.2
Barnum, S.3
Bradt, B.4
Bauer, J.5
Cole, G.M.6
Cooper, N.R.7
Eikelenboom, P.8
Emmerling, M.9
Fiebich, B.L.10
Finch, C.E.11
Frautschy, S.12
Griffin, W.S.13
Hampel, H.14
Hull, M.15
Landreth, G.16
Lue, L.17
Mrak, R.18
Mackenzie, I.R.19
McGeer, P.L.20
O'Banion, M.K.21
Pachter, J.22
Pasinetti, G.23
Plata-Salaman, C.24
Rogers, J.25
Rydel, R.26
Shen, Y.27
Streit, W.28
Strohmeyer, R.29
Tooyoma, I.30
Van Muiswinkel, F.L.31
Veerhuis, R.32
Walker, D.33
Webster, S.34
Wegrzyniak, B.35
Wenk, G.36
Wyss-Coray, T.37
more..
-
2
-
-
0027691633
-
Early and rapid de novo synthesis of Alzheimer beta A4-amyloid precursor protein (APP) in activated microglia
-
Banati R.B., Gehrmann J., Czech C., Mönning U., Jones L.L., König G., Beyreuther K., and Kreutzberg G.W. Early and rapid de novo synthesis of Alzheimer beta A4-amyloid precursor protein (APP) in activated microglia. Glia 9 (1993) 199-210
-
(1993)
Glia
, vol.9
, pp. 199-210
-
-
Banati, R.B.1
Gehrmann, J.2
Czech, C.3
Mönning, U.4
Jones, L.L.5
König, G.6
Beyreuther, K.7
Kreutzberg, G.W.8
-
3
-
-
0025829227
-
In-vitro matured human macrophages express Alzheimer's beta A4-amyloid precursor protein indicating synthesis in microglial cells
-
Bauer J., König G., Strauss S., Jonas U., Ganter U., Weidemann A., Mönning U., Masters C.L., Volk B., and Berger M. In-vitro matured human macrophages express Alzheimer's beta A4-amyloid precursor protein indicating synthesis in microglial cells. FEBS Lett. 282 (1991) 335-340
-
(1991)
FEBS Lett.
, vol.282
, pp. 335-340
-
-
Bauer, J.1
König, G.2
Strauss, S.3
Jonas, U.4
Ganter, U.5
Weidemann, A.6
Mönning, U.7
Masters, C.L.8
Volk, B.9
Berger, M.10
-
4
-
-
0036229777
-
Cytokine levels and phagocytic activity in patients with Alzheimer's disease
-
Beloosesky Y., Salman H., Bergman M., Bessler H., and Djaldetti M. Cytokine levels and phagocytic activity in patients with Alzheimer's disease. Gerontology 48 (2002) 128-132
-
(2002)
Gerontology
, vol.48
, pp. 128-132
-
-
Beloosesky, Y.1
Salman, H.2
Bergman, M.3
Bessler, H.4
Djaldetti, M.5
-
5
-
-
47749107571
-
Independent generation of Abeta 42 and Abeta 38 peptide species by gamma-secretase
-
Czirr E., Cottrell B.A., Leuchtenberger S., Kukar T., Ladd T.B., Esselmann H., Paul S., Schubenel R., Torpey J.W., Pietrzik C.U., Golde T.E., Wiltfang J., Baumann K., Koo E.H., and Weggen S. Independent generation of Abeta 42 and Abeta 38 peptide species by gamma-secretase. J. Biol. Chem. 283 (2008) 17049-17054
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 17049-17054
-
-
Czirr, E.1
Cottrell, B.A.2
Leuchtenberger, S.3
Kukar, T.4
Ladd, T.B.5
Esselmann, H.6
Paul, S.7
Schubenel, R.8
Torpey, J.W.9
Pietrzik, C.U.10
Golde, T.E.11
Wiltfang, J.12
Baumann, K.13
Koo, E.H.14
Weggen, S.15
-
6
-
-
0037431082
-
Aph-1, Pen-2, and Nicastrin with Presenilin generate an active γ-secretase complex
-
De Strooper B. Aph-1, Pen-2, and Nicastrin with Presenilin generate an active γ-secretase complex. Neuron 38 (2003) 9-12
-
(2003)
Neuron
, vol.38
, pp. 9-12
-
-
De Strooper, B.1
-
7
-
-
9244246339
-
Lithium decreases secretion of Abeta1-42 and C-truncated species Abeta1-37/38/39/40 in chicken telencephalic cultures but specifically increases intracellular Abeta1-38
-
Esselmann H., Maler J.M., Kunz N., Otto M., Paul S., Lewczuk P., Ruther E., Kornhuber J., and Wiltfang J. Lithium decreases secretion of Abeta1-42 and C-truncated species Abeta1-37/38/39/40 in chicken telencephalic cultures but specifically increases intracellular Abeta1-38. Neurodegener. Dis. 1 (2004) 236-241
-
(2004)
Neurodegener. Dis.
, vol.1
, pp. 236-241
-
-
Esselmann, H.1
Maler, J.M.2
Kunz, N.3
Otto, M.4
Paul, S.5
Lewczuk, P.6
Ruther, E.7
Kornhuber, J.8
Wiltfang, J.9
-
8
-
-
7344246592
-
Amyloid-beta induces chemokine secretion and monocyte migration across a human blood-brain barrier model
-
Fiala M., Zhang L., Gan X., Sherry B., Taub D., Graves M.C., Hama S., Way D., Weinand M., Witte M., Lorton D., Kuo Y.M., and Roher A.E. Amyloid-beta induces chemokine secretion and monocyte migration across a human blood-brain barrier model. Mol. Med. 4 (1998) 480-489
-
(1998)
Mol. Med.
, vol.4
, pp. 480-489
-
-
Fiala, M.1
Zhang, L.2
Gan, X.3
Sherry, B.4
Taub, D.5
Graves, M.C.6
Hama, S.7
Way, D.8
Weinand, M.9
Witte, M.10
Lorton, D.11
Kuo, Y.M.12
Roher, A.E.13
-
9
-
-
21444454120
-
Ineffective phagocytosis of amyloid-beta by macrophages of Alzheimer's disease patients
-
Fiala M., Lin J., Ringman J., Kermani-Arab V., Tsao G., Patel A., Lossinsky A.S., Graves M.C., Gustavson A., Sayre J., Sofroni E., Suarez T., Chiappelli F., and Bernard G. Ineffective phagocytosis of amyloid-beta by macrophages of Alzheimer's disease patients. J. Alzheimer's Dis. 7 (2005) 221-232
-
(2005)
J. Alzheimer's Dis.
, vol.7
, pp. 221-232
-
-
Fiala, M.1
Lin, J.2
Ringman, J.3
Kermani-Arab, V.4
Tsao, G.5
Patel, A.6
Lossinsky, A.S.7
Graves, M.C.8
Gustavson, A.9
Sayre, J.10
Sofroni, E.11
Suarez, T.12
Chiappelli, F.13
Bernard, G.14
-
10
-
-
0030769091
-
Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides
-
Hartmann T., Bieger S.C., Bruhl B., Tienari P.J., Ida N., Allsop D., Roberts G.W., Masters C.L., Dotti C.G., Unsicker K., and Beyreuther K. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat. Med. 3 (1997) 1016-1020
-
(1997)
Nat. Med.
, vol.3
, pp. 1016-1020
-
-
Hartmann, T.1
Bieger, S.C.2
Bruhl, B.3
Tienari, P.J.4
Ida, N.5
Allsop, D.6
Roberts, G.W.7
Masters, C.L.8
Dotti, C.G.9
Unsicker, K.10
Beyreuther, K.11
-
11
-
-
0026755999
-
Bone marrow-derived elements in the central nervous system: an immunohistochemical and ultrastructural survey of rat chimeras
-
Hickey W.F., Vass K., and Lassmann H. Bone marrow-derived elements in the central nervous system: an immunohistochemical and ultrastructural survey of rat chimeras. J. Neuropathol. Exp. Neurol. 51 (1992) 246-256
-
(1992)
J. Neuropathol. Exp. Neurol.
, vol.51
, pp. 246-256
-
-
Hickey, W.F.1
Vass, K.2
Lassmann, H.3
-
12
-
-
44649183443
-
Prediction of Alzheimer's disease using a cerebrospinal fluid pattern of C-terminally truncated beta-amyloid peptides
-
Höglund K., Hansson O., Buchhave P., Zetterberg H., Lewczuk P., Londos E., Blennow K., Minthon L., and Wiltfang J. Prediction of Alzheimer's disease using a cerebrospinal fluid pattern of C-terminally truncated beta-amyloid peptides. Neurodegener. Dis. 5 (2008) 268-276
-
(2008)
Neurodegener. Dis.
, vol.5
, pp. 268-276
-
-
Höglund, K.1
Hansson, O.2
Buchhave, P.3
Zetterberg, H.4
Lewczuk, P.5
Londos, E.6
Blennow, K.7
Minthon, L.8
Wiltfang, J.9
-
13
-
-
0033133456
-
Beta-amyloid precursor protein is detectable on monocytes and is increased in Alzheimer's disease
-
Jung S.S., Gauthier S., and Cashman N.R. Beta-amyloid precursor protein is detectable on monocytes and is increased in Alzheimer's disease. Neurobiol. Aging 20 (1999) 249-257
-
(1999)
Neurobiol. Aging
, vol.20
, pp. 249-257
-
-
Jung, S.S.1
Gauthier, S.2
Cashman, N.R.3
-
14
-
-
0031559602
-
Isolation, chemical characterization, and quantitation of A beta 3-pyroglutamyl peptide from neuritic plaques and vascular amyloid deposits
-
Kuo Y.M., Emmerling M.R., Woods A.S., Cotter R.J., and Roher A.E. Isolation, chemical characterization, and quantitation of A beta 3-pyroglutamyl peptide from neuritic plaques and vascular amyloid deposits. Biochem. Biophys. Res. Commun. 237 (1997) 188-191
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.237
, pp. 188-191
-
-
Kuo, Y.M.1
Emmerling, M.R.2
Woods, A.S.3
Cotter, R.J.4
Roher, A.E.5
-
15
-
-
0029980902
-
Amyloid precursor protein metabolism in primary cell cultures of neurons, astrocytes, and microglia
-
LeBlanc A.C., Xue R., and Gambetti P. Amyloid precursor protein metabolism in primary cell cultures of neurons, astrocytes, and microglia. J. Neurochem. 66 (1996) 2300-2310
-
(1996)
J. Neurochem.
, vol.66
, pp. 2300-2310
-
-
LeBlanc, A.C.1
Xue, R.2
Gambetti, P.3
-
16
-
-
9144271212
-
Electrophoretic separation of amyloid beta peptides in plasma
-
Lewczuk P., Esselmann H., Bibl M., Paul S., Svitek J., Miertschischk J., Meyrer R., Smirnov A., Maler J.M., Klein C., Otto M., Bleich S., Sperling W., Kornhuber J., Rüther E., and Wiltfang J. Electrophoretic separation of amyloid beta peptides in plasma. Electrophoresis 25 (2004) 3336-3343
-
(2004)
Electrophoresis
, vol.25
, pp. 3336-3343
-
-
Lewczuk, P.1
Esselmann, H.2
Bibl, M.3
Paul, S.4
Svitek, J.5
Miertschischk, J.6
Meyrer, R.7
Smirnov, A.8
Maler, J.M.9
Klein, C.10
Otto, M.11
Bleich, S.12
Sperling, W.13
Kornhuber, J.14
Rüther, E.15
Wiltfang, J.16
-
17
-
-
31844443892
-
Effect of sample collection tubes on cerebrospinal fluid concentrations of tau proteins and amyloid beta peptides
-
Lewczuk P., Beck G., Esselmann H., Bruckmoser R., Zimmermann R., Fiszer M., Bibl M., Maler J.M., Kornhuber J., and Wiltfang J. Effect of sample collection tubes on cerebrospinal fluid concentrations of tau proteins and amyloid beta peptides. Clin. Chem. 52 (2006) 332-334
-
(2006)
Clin. Chem.
, vol.52
, pp. 332-334
-
-
Lewczuk, P.1
Beck, G.2
Esselmann, H.3
Bruckmoser, R.4
Zimmermann, R.5
Fiszer, M.6
Bibl, M.7
Maler, J.M.8
Kornhuber, J.9
Wiltfang, J.10
-
18
-
-
33746049439
-
The German Competence Net Dementias: standard operating procedures for the neurochemical dementia diagnostics
-
Lewczuk P., Kornhuber J., and Wiltfang J. The German Competence Net Dementias: standard operating procedures for the neurochemical dementia diagnostics. J. Neural Transm. 113 (2006) 1075-1080
-
(2006)
J. Neural Transm.
, vol.113
, pp. 1075-1080
-
-
Lewczuk, P.1
Kornhuber, J.2
Wiltfang, J.3
-
19
-
-
35648929821
-
Urea-based two-dimensional electrophoresis of β-amyloid peptides in human plasma: evidence for novel Abeta species
-
Maler J.M., Klafki H.W., Paul S., Spitzer P., Groemer T.W., Henkel A.W., Esselmann H., Lewczuk P., Kornhuber J., and Wiltfang J. Urea-based two-dimensional electrophoresis of β-amyloid peptides in human plasma: evidence for novel Abeta species. Proteomics 7 (2007) 3815-3820
-
(2007)
Proteomics
, vol.7
, pp. 3815-3820
-
-
Maler, J.M.1
Klafki, H.W.2
Paul, S.3
Spitzer, P.4
Groemer, T.W.5
Henkel, A.W.6
Esselmann, H.7
Lewczuk, P.8
Kornhuber, J.9
Wiltfang, J.10
-
20
-
-
0027055588
-
Alzheimer beta A4-amyloid protein precursor in immunocompetent cells
-
Mönning U., König G., Banati R.B., Mechler H., Czech C., Gehrmann J., Schreiter-Gasser U., Masters C.L., and Beyreuther K. Alzheimer beta A4-amyloid protein precursor in immunocompetent cells. J. Biol. Chem. 267 (1992) 23950-23956
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 23950-23956
-
-
Mönning, U.1
König, G.2
Banati, R.B.3
Mechler, H.4
Czech, C.5
Gehrmann, J.6
Schreiter-Gasser, U.7
Masters, C.L.8
Beyreuther, K.9
-
21
-
-
0036813533
-
Regulation of amyloid beta-peptide levels by enzymatic degradation
-
Mukherjee A., and Hersh L.B. Regulation of amyloid beta-peptide levels by enzymatic degradation. J. Alzheimer's Dis. 4 (2002) 341-348
-
(2002)
J. Alzheimer's Dis.
, vol.4
, pp. 341-348
-
-
Mukherjee, A.1
Hersh, L.B.2
-
22
-
-
12444337654
-
Truncated beta-amyloid peptide species in pre-clinical Alzheimer's disease as new targets for the vaccination approach
-
Sergeant N., Bombois S., Ghestem A., Drobecq H., Kostanjevecki V., Missiaen C., Wattez A., David J.P., Vanmechelen E., Sergheraert C., and Delacourte A. Truncated beta-amyloid peptide species in pre-clinical Alzheimer's disease as new targets for the vaccination approach. J. Neurochem. 85 (2003) 1581-1591
-
(2003)
J. Neurochem.
, vol.85
, pp. 1581-1591
-
-
Sergeant, N.1
Bombois, S.2
Ghestem, A.3
Drobecq, H.4
Kostanjevecki, V.5
Missiaen, C.6
Wattez, A.7
David, J.P.8
Vanmechelen, E.9
Sergheraert, C.10
Delacourte, A.11
-
23
-
-
34250328818
-
Pathological activity of familial Alzheimer's disease-associated mutant presenilin can be executed by six different γ-secretase complexes
-
Shirotani K., Tomioka M., Kremmer E., Haass C., and Steiner H. Pathological activity of familial Alzheimer's disease-associated mutant presenilin can be executed by six different γ-secretase complexes. Neurobiol. Dis. 27 (2007) 102-107
-
(2007)
Neurobiol. Dis.
, vol.27
, pp. 102-107
-
-
Shirotani, K.1
Tomioka, M.2
Kremmer, E.3
Haass, C.4
Steiner, H.5
-
24
-
-
0036277146
-
Amyloid-beta-induced chemokine production in primary human macrophages and astrocytes
-
Smits H.A., Rijsmus A., van Loon J.H., Wat J.W., Verhoef J., Boven L.A., and Nottet H.S. Amyloid-beta-induced chemokine production in primary human macrophages and astrocytes. J. Neuroimmunol. 127 (2002) 160-168
-
(2002)
J. Neuroimmunol.
, vol.127
, pp. 160-168
-
-
Smits, H.A.1
Rijsmus, A.2
van Loon, J.H.3
Wat, J.W.4
Verhoef, J.5
Boven, L.A.6
Nottet, H.S.7
-
25
-
-
33645296845
-
Amyloid precursor protein cross-linking stimulates beta amyloid production and pro-inflammatory cytokine release in monocytic lineage cells
-
Sondag C.M., and Combs C.K. Amyloid precursor protein cross-linking stimulates beta amyloid production and pro-inflammatory cytokine release in monocytic lineage cells. J. Neurochem. 97 (2006) 449-461
-
(2006)
J. Neurochem.
, vol.97
, pp. 449-461
-
-
Sondag, C.M.1
Combs, C.K.2
-
26
-
-
34547328074
-
New insights into the roles of metalloproteinases in neurodegeneration and neuroprotection
-
Turner A.J., and Nalivaeva N.N. New insights into the roles of metalloproteinases in neurodegeneration and neuroprotection. Int. Rev. Neurobiol. 82 (2007) 113-135
-
(2007)
Int. Rev. Neurobiol.
, vol.82
, pp. 113-135
-
-
Turner, A.J.1
Nalivaeva, N.N.2
-
27
-
-
0033118464
-
The amino-terminus of the amyloid-beta protein is critical for the cellular binding and consequent activation of the respiratory burst of human macrophages
-
Van Muiswinkel F.L., Raupp S.F., de Vos N.M., Smits H.A., Verhoef J., Eikelenboom P., and Nottet H.S. The amino-terminus of the amyloid-beta protein is critical for the cellular binding and consequent activation of the respiratory burst of human macrophages. J. Neuroimmunol. 96 (1999) 121-130
-
(1999)
J. Neuroimmunol.
, vol.96
, pp. 121-130
-
-
Van Muiswinkel, F.L.1
Raupp, S.F.2
de Vos, N.M.3
Smits, H.A.4
Verhoef, J.5
Eikelenboom, P.6
Nottet, H.S.7
-
28
-
-
4444323422
-
Cells of monocyte/microglial lineage are involved in both microvessel amyloidosis and fibrillar plaque formation in APPsw tg mice
-
Wegiel J., Imaki H., Wang K.C., Wegiel J., and Rubenstein R. Cells of monocyte/microglial lineage are involved in both microvessel amyloidosis and fibrillar plaque formation in APPsw tg mice. Brain Res. 1022 (2004) 19-29
-
(2004)
Brain Res.
, vol.1022
, pp. 19-29
-
-
Wegiel, J.1
Imaki, H.2
Wang, K.C.3
Wegiel, J.4
Rubenstein, R.5
-
29
-
-
0035900774
-
Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells
-
Wiltfang J., Esselmann H., Cupers P., Neumann M., Kretzschmar H., Beyermann M., Schleuder D., Jahn H., Rüther E., Kornhuber J., Annaert W., De Strooper B., and Saftig P. Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells. J. Biol. Chem. 276 (2001) 42645-42657
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 42645-42657
-
-
Wiltfang, J.1
Esselmann, H.2
Cupers, P.3
Neumann, M.4
Kretzschmar, H.5
Beyermann, M.6
Schleuder, D.7
Jahn, H.8
Rüther, E.9
Kornhuber, J.10
Annaert, W.11
De Strooper, B.12
Saftig, P.13
-
30
-
-
18444393054
-
Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation
-
Wiltfang J., Esselmann H., Bibl M., Smirnov A., Otto M., Paul S., Schmidt B., Klafki H.W., Maler M., Dyrks T., Bienert M., Beyermann M., Rüther E., and Kornhuber J. Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation. J. Neurochem. 81 (2002) 481-496
-
(2002)
J. Neurochem.
, vol.81
, pp. 481-496
-
-
Wiltfang, J.1
Esselmann, H.2
Bibl, M.3
Smirnov, A.4
Otto, M.5
Paul, S.6
Schmidt, B.7
Klafki, H.W.8
Maler, M.9
Dyrks, T.10
Bienert, M.11
Beyermann, M.12
Rüther, E.13
Kornhuber, J.14
-
31
-
-
0026685656
-
Ultrastructural studies of the cells forming amyloid in the cortical vessel wall in Alzheimer's disease
-
Wisniewski H.M., Wegiel J., Wang K.C., and Lach B. Ultrastructural studies of the cells forming amyloid in the cortical vessel wall in Alzheimer's disease. Acta Neuropathol. 84 (1992) 117-127
-
(1992)
Acta Neuropathol.
, vol.84
, pp. 117-127
-
-
Wisniewski, H.M.1
Wegiel, J.2
Wang, K.C.3
Lach, B.4
|