-
1
-
-
0037441856
-
Phase III trial of doxorubicin, paclitaxel, and the combination of doxorubicin and paclitaxel as front-line chemotherapy for metastatic breast cancer: An Intergroup trial (E1193)
-
-
Sledge GW, Neuberg D, Bernardo P, et al. Phase III trial of doxorubicin, paclitaxel, and the combination of doxorubicin and paclitaxel as front-line chemotherapy for metastatic breast cancer: an Intergroup trial (E1193). J Clin Oncol 2003; 21:588-92.
-
(2003)
J Clin Oncol
, vol.21
, pp. 588-592
-
-
Sledge, G.W.1
Neuberg, D.2
Bernardo, P.3
-
2
-
-
0031004468
-
Cyclophosphamide and fluorouracil combined with mitoxantrone versus doxorubicin for breast cancer: Superiority of doxorubicin
-
-
Stewart DJ, Evans WK, Shepherd FA, et al. Cyclophosphamide and fluorouracil combined with mitoxantrone versus doxorubicin for breast cancer: superiority of doxorubicin. J Clin Oncol 1997; 15:1897-905.
-
(1997)
J Clin Oncol
, vol.15
, pp. 1897-1905
-
-
Stewart, D.J.1
Evans, W.K.2
Shepherd, F.A.3
-
5
-
-
53449087422
-
RiBBON 1 and RiBBON 2: Phase III trials of bevacizumab with standard chemotherapy for metastatic breast cancer
-
-
O'Shaughnessy JA, Brufsky AM. RiBBON 1 and RiBBON 2: phase III trials of bevacizumab with standard chemotherapy for metastatic breast cancer. Clin Breast Cancer 2008; 8:370-3.
-
(2008)
Clin Breast Cancer
, vol.8
, pp. 370-373
-
-
O'Shaughnessy, J.A.1
Brufsky, A.M.2
-
12
-
-
34247241630
-
The decrease in breast-cancer incidence in 2003 in the United States
-
-
Ravdin PM, Cronin KA, Howlader N, et al. The decrease in breast-cancer incidence in 2003 in the United States. N Engl J Med 2007; 356:1670-4.
-
(2007)
N Engl J Med
, vol.356
, pp. 1670-1674
-
-
Ravdin, P.M.1
Cronin, K.A.2
Howlader, N.3
-
13
-
-
84898692215
-
Major changes in breast cancer incidence in the United States over the period 2002 to 2004
-
, 18 suppl):69s Abstract 1533
-
Ravdin PM, Cronin KA, Howlader N, et al. Major changes in breast cancer incidence in the United States over the period 2002 to 2004. J Clin Oncol 2007; 25(18 suppl):69s (Abstract 1533).
-
(2007)
J Clin Oncol
, pp. 25
-
-
Ravdin, P.M.1
Cronin, K.A.2
Howlader, N.3
-
14
-
-
41349099104
-
Cancer Statistics, 2008
-
-
Jemal A, Siegel R, Ward E, et al. Cancer Statistics, 2008. CA Cancer J Clin 2008; 58:71-96.
-
(2008)
CA Cancer J Clin
, vol.58
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
-
15
-
-
0036307010
-
Second and subsequent lines of chemotherapy for metastatic breast cancer: What did we learn in the last two decades
-
-
Cardoso F, Di LA, Lohrisch C. Second and subsequent lines of chemotherapy for metastatic breast cancer: what did we learn in the last two decades. Ann Oncol 2002; 13:197-207.
-
(2002)
Ann Oncol
, vol.13
, pp. 197-207
-
-
Cardoso, F.1
Di, L.A.2
Lohrisch, C.3
-
16
-
-
31444447160
-
Extending survival with chemotherapy in metastatic breast cancer
-
-
O'Shaughnessy J. Extending survival with chemotherapy in metastatic breast cancer. Oncologist 2005; 10(suppl 3):20-9.
-
(2005)
Oncologist
, vol.10
, Issue.SUPPL. 3
, pp. 20-29
-
-
O'Shaughnessy, J.1
-
17
-
-
32944482677
-
Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer
-
-
Gradishar WJ, Tjulandin S, Davidson N, et al. Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer. J Clin Oncol 2005; 23:7794-803.
-
(2005)
J Clin Oncol
, vol.23
, pp. 7794-7803
-
-
Gradishar, W.J.1
Tjulandin, S.2
Davidson, N.3
-
18
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
-
Slamon DJ, Leyland-Jones B, Shak S, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001; 344:783-92.
-
(2001)
N Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
-
19
-
-
0025743487
-
Classical CMF versus a 3-weekly intravenous CMF schedule in postmenopausal patients with advanced breast cancer. An EORTC Breast Cancer Co-operative Group Phase III Trial (10808)
-
-
Engelsman E, Klijn JC, Rubens RD, et al. "Classical" CMF versus a 3-weekly intravenous CMF schedule in postmenopausal patients with advanced breast cancer. An EORTC Breast Cancer Co-operative Group Phase III Trial (10808). Eur J Cancer 1991; 27:966-70.
-
(1991)
Eur J Cancer
, vol.27
, pp. 966-970
-
-
Engelsman, E.1
Klijn, J.C.2
Rubens, R.D.3
-
20
-
-
27244438750
-
Phase II to III study comparing doxorubicin and docetaxel with fluorouracil, doxorubicin, and cyclophosphamide as first-line chemotherapy in patients with metastatic breast cancer: Results of a Dutch Community Setting Trial for the Clinical Trial Group of the Comprehensive Cancer Centre
-
-
Bontenbal M, Creemers GJ, Braun HJ, et al. Phase II to III study comparing doxorubicin and docetaxel with fluorouracil, doxorubicin, and cyclophosphamide as first-line chemotherapy in patients with metastatic breast cancer: results of a Dutch Community Setting Trial for the Clinical Trial Group of the Comprehensive Cancer Centre. J Clin Oncol 2005; 23:7081-8.
-
(2005)
J Clin Oncol
, vol.23
, pp. 7081-7088
-
-
Bontenbal, M.1
Creemers, G.J.2
Braun, H.J.3
-
21
-
-
0035868906
-
Doxorubicin and paclitaxel versus fluorouracil, doxorubicin, and cyclophosphamide as first-line therapy for women with metastatic breast cancer: Final results of a randomized phase III multicenter trial
-
-
Jassem J, Pienkowski T, Pluzåska A, et al. Doxorubicin and paclitaxel versus fluorouracil, doxorubicin, and cyclophosphamide as first-line therapy for women with metastatic breast cancer: final results of a randomized phase III multicenter trial. J Clin Oncol 2001; 19:1707-15.
-
(2001)
J Clin Oncol
, vol.19
, pp. 1707-1715
-
-
Jassem, J.1
Pienkowski, T.2
Pluzåska, A.3
-
22
-
-
34247243265
-
Phase II combined biological therapy targeting the HER2 proto-oncogene and the vascular endothelial growth factor using trastuzumab (T) and bevacizumab (B) as first line treatment of HER2-amplified breast cancer
-
, Abstract 301
-
Pegram M, Chan D, Dichmann RA, et al. Phase II combined biological therapy targeting the HER2 proto-oncogene and the vascular endothelial growth factor using trastuzumab (T) and bevacizumab (B) as first line treatment of HER2-amplified breast cancer. Breast Cancer Res Treat 2006; 100(suppl 1):21 (Abstract 301).
-
(2006)
Breast Cancer Res Treat
, vol.100
, Issue.SUPPL. 1
, pp. 21
-
-
Pegram, M.1
Chan, D.2
Dichmann, R.A.3
-
23
-
-
35248830049
-
Breast-cancer therapyâlooking back to the future
-
-
Moore A. Breast-cancer therapyâ"looking back to the future. N Engl J Med 2007; 357:1547-9.
-
(2007)
N Engl J Med
, vol.357
, pp. 1547-1549
-
-
Moore, A.1
-
24
-
-
74649084265
-
Phase II feasibility trial incorporating bevacizumab into dose dense doxorubicin and cyclophosphamide followed by paclitaxel in patients with lymph node positive breast cancer: A trial of the Eastern Cooperative Oncology Group (E2104)
-
Presented at: December 13-16, San Antonio, TX. Abstract 3063
-
Miller KD, O'Neil A, Perez EA, et al. Phase II feasibility trial incorporating bevacizumab into dose dense doxorubicin and cyclophosphamide followed by paclitaxel in patients with lymph node positive breast cancer: a trial of the Eastern Cooperative Oncology Group (E2104). Presented at: the 30th Annual San Antonio Breast Cancer Symposium; December 13-16, 2007; San Antonio, TX. Abstract 3063.
-
(2007)
the 30th Annual San Antonio Breast Cancer Symposium
-
-
Miller, K.D.1
O'Neil, A.2
Perez, E.A.3
-
25
-
-
50949110987
-
Cardiac safety of adjuvant bevacizumab plus dose-dense doxorubicin/cyclophosphamide followed by nanoparticle albumin-bound paclitaxel in patients with early stage breast cancer
-
Presented at: December 13-16, San Antonio, TX. Abstract 3065
-
Mcarthur HL, Rugo H, Paulson M, et al. Cardiac safety of adjuvant bevacizumab plus dose-dense doxorubicin/cyclophosphamide followed by nanoparticle albumin-bound paclitaxel in patients with early stage breast cancer. Presented at: the 30th Annual San Antonio Breast Cancer Symposium; December 13-16, 2007; San Antonio, TX. Abstract 3065.
-
(2007)
the 30th Annual San Antonio Breast Cancer Symposium
-
-
Mcarthur, H.L.1
Rugo, H.2
Paulson, M.3
-
26
-
-
39149105497
-
Safety and efficacy of capecitabine (C) plus bevacizumab (B) as first-line in metastatic breast cancer
-
, 18 suppl):35s Abstract 1013
-
Sledge G, Miller K, Moisa C, et al. Safety and efficacy of capecitabine (C) plus bevacizumab (B) as first-line in metastatic breast cancer. J Clin Oncol 2007; 25(18 suppl):35s (Abstract 1013).
-
(2007)
J Clin Oncol
, pp. 25
-
-
Sledge, G.1
Miller, K.2
Moisa, C.3
-
27
-
-
33744812137
-
Phase II trial of bevacizumab in combination with weekly docetaxel in metastatic breast cancer patients
-
-
Ramaswamy B, Elias AD, Kelbick NT, et al. Phase II trial of bevacizumab in combination with weekly docetaxel in metastatic breast cancer patients. Clin Cancer Res 2006; 12:3124-9.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3124-3129
-
-
Ramaswamy, B.1
Elias, A.D.2
Kelbick, N.T.3
-
28
-
-
84898699743
-
North Central cancer treatment group (NCCTG) N0432: Phase II trial of docetaxel with capecitabine and bevacizumab as first line chemotherapy for patients with metastatic breast cancer
-
Presented at: December 14-17, San Antonio, TX. Abstract 2069
-
Perez EA, Hillman DW, Kugler JW, et al. North Central cancer treatment group (NCCTG) N0432: phase II trial of docetaxel with capecitabine and bevacizumab as first line chemotherapy for patients with metastatic breast cancer. Presented at: the 29th Annual San Antonio Breast Cancer Symposium; December 14-17, 2006; San Antonio, TX. Abstract 2069.
-
(2006)
the 29th Annual San Antonio Breast Cancer Symposium
-
-
Perez, E.A.1
Hillman, D.W.2
Kugler, J.W.3
-
29
-
-
84898692629
-
-
Conlin AK, Seidman AD, Moynahan ME, et al. Randomized phase II trial of three dosing schedules of nanoparticle albumin-bound paclitaxel with bevacizumab as first-line therapy for HER2-negative metastatic breast cancer: an initial interim safety report. J Clin Oncol 2007; 25(18 suppl):58s (Abstract 1104).
-
Conlin AK, Seidman AD, Moynahan ME, et al. Randomized phase II trial of three dosing schedules of nanoparticle albumin-bound paclitaxel with bevacizumab as first-line therapy for HER2-negative metastatic breast cancer: an initial interim safety report. J Clin Oncol 2007; 25(18 suppl):58s (Abstract 1104).
-
-
-
-
30
-
-
33748528270
-
Letrozole (L) with bevacizumab (B) is feasible in patients (pts) with hormone receptor-positive metastatic breast cancer (MBC)
-
, 18 suppl):133s Abstract 3050
-
Traina TA, Rugo H, Caravelli J, et al. Letrozole (L) with bevacizumab (B) is feasible in patients (pts) with hormone receptor-positive metastatic breast cancer (MBC). J Clin Oncol 2006; 24(18 suppl):133s (Abstract 3050).
-
(2006)
J Clin Oncol
, pp. 24
-
-
Traina, T.A.1
Rugo, H.2
Caravelli, J.3
-
31
-
-
7944228610
-
Phase II trial of erlotinib (OSI-774), an epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor, and bevacizumab, a recombinant humanized monoclonal antibody to vascular endothelial growth factor (VEGF), in patients (pts) with metastatic breast cancer (MBC)
-
, Abstract
-
Dickler M, Rugo H, Caravelli J, et al. Phase II trial of erlotinib (OSI-774), an epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor, and bevacizumab, a recombinant humanized monoclonal antibody to vascular endothelial growth factor (VEGF), in patients (pts) with metastatic breast cancer (MBC). Proc Am Soc Clin Oncol 2004; 23:127 (Abstract 2001).
-
(2001)
Proc Am Soc Clin Oncol
, vol.23
, pp. 127
-
-
Dickler, M.1
Rugo, H.2
Caravelli, J.3
-
32
-
-
84898696964
-
-
Grothey A, Sugrue M, Hedrick E, et al. Association between exposure to Bevacizumab (BV) beyond first progression (BBP) and overall survival (OS) in patients (pts) with metastatic colorectal cancer (mCRC): results from a large observational study (BRiTE). J Clin Oncol 2007; 25(18 suppl)172s (Abstract 4036).
-
Grothey A, Sugrue M, Hedrick E, et al. Association between exposure to Bevacizumab (BV) beyond first progression (BBP) and overall survival (OS) in patients (pts) with metastatic colorectal cancer (mCRC): results from a large observational study (BRiTE). J Clin Oncol 2007; 25(18 suppl)172s (Abstract 4036).
-
-
-
-
33
-
-
0034691674
-
Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis
-
-
Yen L, You XL, Al Moustafa AE, et al. Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis. Oncogene 2000; 19:3460-9.
-
(2000)
Oncogene
, vol.19
, pp. 3460-3469
-
-
Yen, L.1
You, X.L.2
Al Moustafa, A.E.3
-
34
-
-
12144291334
-
Association between HER-2/neu and vascular endothelial growth factor expression predicts clinical outcome in primary breast cancer patients
-
-
Konecny GE, Meng YG, Untch M, et al. Association between HER-2/neu and vascular endothelial growth factor expression predicts clinical outcome in primary breast cancer patients. Clin Cancer Res 2004; 10:1706-16.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 1706-1716
-
-
Konecny, G.E.1
Meng, Y.G.2
Untch, M.3
-
35
-
-
0032809977
-
Initial paclitaxel improves outcome compared with CMFP combination chemotherapy as front-line therapy in untreated metastatic breast cancer
-
-
Bishop JF, Dewar J, Toner GC, et al. Initial paclitaxel improves outcome compared with CMFP combination chemotherapy as front-line therapy in untreated metastatic breast cancer. J Clin Oncol 1999; 17:2355-64.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2355-2364
-
-
Bishop, J.F.1
Dewar, J.2
Toner, G.C.3
-
36
-
-
84898700118
-
-
Proc Am Soc Clin Oncol, Abstract 512
-
Seidman AD, Berry D, Cirrincione C, et al. CALGB 9840: phase III study of weekly (W) paclitaxel (P) via 1-hour(h) infusion versus standard (S) 3h infusion every third week in the treatment of metastatic breast cancer (MBC), with trastuzumab (T) for HER2 positive MBC and randomized for T in HER2 normal MBC. Proc Am Soc Clin Oncol 2004; 23:6 (Abstract 512).
-
(2004)
CALGB 9840: Phase III study of weekly (W) paclitaxel (P) via 1-hour(h) infusion versus standard (S) 3h infusion every third week in the treatment of metastatic breast cancer (MBC), with trastuzumab (T) for HER2 positive MBC and randomized for T in HER2 normal MBC
, vol.23
, pp. 6
-
-
Seidman, A.D.1
Berry, D.2
Cirrincione, C.3
-
37
-
-
0037096755
-
Superior survival with capecitabine plus docetaxel combination therapy in anthracycline-pretreated patients with advanced breast cancer: Phase III trial results
-
-
O'Shaughnessy J, Miles D, Vukelja S, et al. Superior survival with capecitabine plus docetaxel combination therapy in anthracycline-pretreated patients with advanced breast cancer: phase III trial results. J Clin Oncol 2002; 20:2812-23.
-
(2002)
J Clin Oncol
, vol.20
, pp. 2812-2823
-
-
O'Shaughnessy, J.1
Miles, D.2
Vukelja, S.3
-
38
-
-
0032949449
-
Prospective randomized trial of docetaxel versus mitomycin plus vinblastine in patients with metastatic breast cancer progressing despite previous anthracycline-containing chemotherapy. 304 Study Group
-
-
Nabholtz JM, Senn HJ, Bezwoda WR, et al. Prospective randomized trial of docetaxel versus mitomycin plus vinblastine in patients with metastatic breast cancer progressing despite previous anthracycline-containing chemotherapy. 304 Study Group. J Clin Oncol 1999; 17:1413-24.
-
(1999)
J Clin Oncol
, vol.17
, pp. 1413-1424
-
-
Nabholtz, J.M.1
Senn, H.J.2
Bezwoda, W.R.3
-
39
-
-
24944507764
-
Randomized phase III study of docetaxel compared with paclitaxel in metastatic breast cancer
-
-
Jones SE, Erban J, Overmoyer B, et al. Randomized phase III study of docetaxel compared with paclitaxel in metastatic breast cancer. J Clin Oncol 2005; 23:5542-51.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5542-5551
-
-
Jones, S.E.1
Erban, J.2
Overmoyer, B.3
-
40
-
-
33845886440
-
Lapatinib plus capecitabine for HER2-positive advanced breast cancer
-
-
Geyer CE, Forster J, Lindquist D, et al. Lapatinib plus capecitabine for HER2-positive advanced breast cancer. N Engl J Med 2006; 355:2733-43.
-
(2006)
N Engl J Med
, vol.355
, pp. 2733-2743
-
-
Geyer, C.E.1
Forster, J.2
Lindquist, D.3
-
41
-
-
36849071808
-
Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracyclines and taxane treatment
-
-
Thomas ES, Gomez HL, Li RK, et al. Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracyclines and taxane treatment. J Clin Oncol 2007; 25:5210-7.
-
(2007)
J Clin Oncol
, vol.25
, pp. 5210-5217
-
-
Thomas, E.S.1
Gomez, H.L.2
Li, R.K.3
-
42
-
-
0029092360
-
Randomized comparison of vinorelbine and melphalan in anthracycline-refractory advanced breast cancer
-
-
Jones S, Winer E, Vogel C, et al. Randomized comparison of vinorelbine and melphalan in anthracycline-refractory advanced breast cancer. J Clin Oncol 1995; 13:2567-74.
-
(1995)
J Clin Oncol
, vol.13
, pp. 2567-2574
-
-
Jones, S.1
Winer, E.2
Vogel, C.3
-
43
-
-
0032787785
-
Prospective randomized trial of docetaxel versus doxorubicin in patients with metastatic breast cancer
-
-
Chan S, Friedrichs K, Noel D, et al. Prospective randomized trial of docetaxel versus doxorubicin in patients with metastatic breast cancer. J Clin Oncol 1999; 17:2341-54.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2341-2354
-
-
Chan, S.1
Friedrichs, K.2
Noel, D.3
-
44
-
-
0034614637
-
The hallmarks of cancer
-
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
45
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
-
Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971; 285:1182-6.
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
46
-
-
0027043136
-
Tumor angiogenesis: A new significant and independent prognostic indicator in early-stage breast carcinoma
-
-
Weidner N, Folkman J, Pozza F, et al. Tumor angiogenesis: a new significant and independent prognostic indicator in early-stage breast carcinoma. J Natl Cancer Inst 1992; 84:1875-87.
-
(1992)
J Natl Cancer Inst
, vol.84
, pp. 1875-1887
-
-
Weidner, N.1
Folkman, J.2
Pozza, F.3
-
48
-
-
41549126916
-
Antiangiogenesis agents
-
DeVita VT, Hellman S, Rosenberg SA, eds. . 7th ed. Philadelphia, PA: Lippincott Williams & Wilkins;
-
Folkman J. Antiangiogenesis agents. In: DeVita VT, Hellman S, Rosenberg SA, eds. Cancer: Principles and Practice of Oncology. 7th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2004:2865-82.
-
(2004)
Cancer: Principles and Practice of Oncology
, pp. 2865-2882
-
-
Folkman, J.1
-
49
-
-
0031038068
-
Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis
-
-
Relf M, LeJeune S, Scott PA, et al. Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis. Cancer Res 1997; 57:963-9.
-
(1997)
Cancer Res
, vol.57
, pp. 963-969
-
-
Relf, M.1
LeJeune, S.2
Scott, P.A.3
-
50
-
-
0028861231
-
Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer
-
-
Brown LF, Berse B, Jackman RW, et al. Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer. Hum Pathol 1995; 26:86-91.
-
(1995)
Hum Pathol
, vol.26
, pp. 86-91
-
-
Brown, L.F.1
Berse, B.2
Jackman, R.W.3
-
51
-
-
42549161196
-
The assessment of angiogenesis and fibroblastic stromagenesis in hyperplastic and pre-invasive breast lesions
-
-
Pavlakis K, Messini I, Vrekoussis T, et al. The assessment of angiogenesis and fibroblastic stromagenesis in hyperplastic and pre-invasive breast lesions. BMC Cancer 2008; 8:88.
-
(2008)
BMC Cancer
, vol.8
, pp. 88
-
-
Pavlakis, K.1
Messini, I.2
Vrekoussis, T.3
-
52
-
-
0029143990
-
Tumor angiogenesis in breast cancer: Its importance as a prognostic indicator and the association with vascular endothelial growth factor expression
-
-
Toi M, Inada K, Suzuki H, et al. Tumor angiogenesis in breast cancer: its importance as a prognostic indicator and the association with vascular endothelial growth factor expression. Breast Cancer Res Treat 1995; 36:193-204.
-
(1995)
Breast Cancer Res Treat
, vol.36
, pp. 193-204
-
-
Toi, M.1
Inada, K.2
Suzuki, H.3
-
53
-
-
0032943036
-
Clinical relevance of vascular endothelial growth factor and thymidine phosphorylase in patients with node-positive breast cancer treated with either adjuvant chemotherapy or hormone therapy
-
-
Gasparini G, Toi M, Miceli R, et al. Clinical relevance of vascular endothelial growth factor and thymidine phosphorylase in patients with node-positive breast cancer treated with either adjuvant chemotherapy or hormone therapy. Cancer J Sci Am 1999; 5:101-11.
-
(1999)
Cancer J Sci Am
, vol.5
, pp. 101-111
-
-
Gasparini, G.1
Toi, M.2
Miceli, R.3
-
54
-
-
84898700478
-
-
Avastinâ® bevacizumab, package insert, South San Francisco: Genentech, Inc; 2008
-
Avastinâ® (bevacizumab) [package insert]. South San Francisco: Genentech, Inc; 2008.
-
-
-
-
55
-
-
2442621619
-
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
-
-
Ferrara N, Hillan KJ, Gerber HP, et al. Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nat Rev Drug Discov 2004; 3:391-400.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 391-400
-
-
Ferrara, N.1
Hillan, K.J.2
Gerber, H.P.3
-
56
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
-
Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350:2335-42.
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
57
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
-
Sandler A, Gray R, Perry MC, et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 2006; 355:2542-50.
-
(2006)
N Engl J Med
, vol.355
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
-
58
-
-
11144354392
-
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
-
-
Willett CG, Boucher Y, di Tomaso E, et al. Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer. Nat Med 2004; 10:145-7.
-
(2004)
Nat Med
, vol.10
, pp. 145-147
-
-
Willett, C.G.1
Boucher, Y.2
di Tomaso, E.3
-
59
-
-
12344312042
-
Cellular abnormalities of blood vessels as targets in cancer
-
-
Baluk P, Hashizume H, McDonald DM. Cellular abnormalities of blood vessels as targets in cancer. Curr Opin Genet Dev 2005; 15:102-11.
-
(2005)
Curr Opin Genet Dev
, vol.15
, pp. 102-111
-
-
Baluk, P.1
Hashizume, H.2
McDonald, D.M.3
-
60
-
-
0038235987
-
Effect of antivascular endothelial growth factor treatment on the intratumoral uptake of CPT-11
-
-
Wildiers H, Guetens G, De Boeck G, et al. Effect of antivascular endothelial growth factor treatment on the intratumoral uptake of CPT-11. Br J Cancer 2003; 88:1979-86.
-
(2003)
Br J Cancer
, vol.88
, pp. 1979-1986
-
-
Wildiers, H.1
Guetens, G.2
De Boeck, G.3
-
61
-
-
3042548695
-
Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts
-
-
Inai T, Mancuso M, Hashizume H, et al. Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts. Am J Pathol 2004; 165:35-52.
-
(2004)
Am J Pathol
, vol.165
, pp. 35-52
-
-
Inai, T.1
Mancuso, M.2
Hashizume, H.3
-
62
-
-
0242468884
-
A phase I/II dose-escalation trial of bevacizumab in previously treated metastatic breast cancer
-
-
Cobleigh MA, Langmuir VK, Sledge GW, et al. A phase I/II dose-escalation trial of bevacizumab in previously treated metastatic breast cancer. Semin Oncol 2003; 30 (5 suppl 16):117-24.
-
(2003)
Semin Oncol
, vol.30
, Issue.5 SUPPL. 16
, pp. 117-124
-
-
Cobleigh, M.A.1
Langmuir, V.K.2
Sledge, G.W.3
-
63
-
-
49749124673
-
Clinical pharmacokinetics of bevacizumab in patients with solid tumors
-
-
Lu JF, Bruno R, Eppler S, et al. Clinical pharmacokinetics of bevacizumab in patients with solid tumors. Cancer Chemother Pharmacol 2008; 62:779-86.
-
(2008)
Cancer Chemother Pharmacol
, vol.62
, pp. 779-786
-
-
Lu, J.F.1
Bruno, R.2
Eppler, S.3
-
64
-
-
42949150908
-
Randomized phase III study of capecitabine plus oxaliplatin compared with fluorouracil/folinic acid plus oxaliplatin as first-line therapy for metastatic colorectal cancer
-
-
Cassidy J, Clarke S, Dãaz-Rubio E, et al. Randomized phase III study of capecitabine plus oxaliplatin compared with fluorouracil/folinic acid plus oxaliplatin as first-line therapy for metastatic colorectal cancer. J Clin Oncol 2008; 26:2006-12.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2006-2012
-
-
Cassidy, J.1
Clarke, S.2
Dãaz-Rubio, E.3
-
65
-
-
20044364346
-
Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer
-
-
Miller KD, Chap LI, Holmes FA, et al. Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer. J Clin Oncol 2005; 23:792-9.
-
(2005)
J Clin Oncol
, vol.23
, pp. 792-799
-
-
Miller, K.D.1
Chap, L.I.2
Holmes, F.A.3
-
66
-
-
37549040613
-
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
-
-
Miller K, Wang M, Gralow J, et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med 2007; 357:2666-76.
-
(2007)
N Engl J Med
, vol.357
, pp. 2666-2676
-
-
Miller, K.1
Wang, M.2
Gralow, J.3
-
67
-
-
84898690542
-
-
Miles D, Chan A, Romieu G, et al. Randomized, double-blind, placebo-controlled, phase III study of bevacizumab with docetaxel or docetaxel with placebo as first-line therapy for patients with locally recurrent or metastatic breast cancer (mBC): AVADO. Presented at: the American Society of Clinical Oncology Annual Meeting; May 30-June 3, 2008; Chicago, IL. Abstract LBA1011.
-
Miles D, Chan A, Romieu G, et al. Randomized, double-blind, placebo-controlled, phase III study of bevacizumab with docetaxel or docetaxel with placebo as first-line therapy for patients with locally recurrent or metastatic breast cancer (mBC): AVADO. Presented at: the American Society of Clinical Oncology Annual Meeting; May 30-June 3, 2008; Chicago, IL. Abstract LBA1011.
-
-
-
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