메뉴 건너뛰기




Volumn 61, Issue 1, 2009, Pages 63-67

Human phenylalanine monooxygenase and thioether metabolism

Author keywords

Metabolism; Phenylalanine hydroxylase; Phenylalanine monooxygenase; S carboxymethyl L cysteine; Thioethers

Indexed keywords

CARBOCISTEINE; CYSTEINE DERIVATIVE; PHENYLALANINE; PHENYLALANINE 4 MONOOXYGENASE; PHENYLALANINE MONOOXYGENASE; S BUTYLCYSTEINE; S ETHYLCYSTEINE; S PROPYLCYSTEINE; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

EID: 58149231200     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.61.01.0009     Document Type: Article
Times cited : (15)

References (23)
  • 1
    • 33750125570 scopus 로고    scopus 로고
    • The sulphoxidation of S-carboxymethyl- L-cysteine in COPD
    • Steventon GB, Mitchell SC. The sulphoxidation of S-carboxymethyl- L-cysteine in COPD. Eur Respir J 2006; 27: 865-866.
    • (2006) Eur Respir J , vol.27 , pp. 865-866
    • Steventon, G.B.1    Mitchell, S.C.2
  • 2
    • 33745631001 scopus 로고    scopus 로고
    • Efficacy of S-carboxymethyl-Lcysteine for otitis media with effusion
    • Steventon GB, Mitchell SC. Efficacy of S-carboxymethyl-Lcysteine for otitis media with effusion. Ear Nose Throat J 2006; 85: 296-297.
    • (2006) Ear Nose Throat J , vol.85 , pp. 296-297
    • Steventon, G.B.1    Mitchell, S.C.2
  • 3
    • 0038519277 scopus 로고    scopus 로고
    • Carbocysteine lysine salt monohydrate (SCMC-LYS) is a selective scavenger of reactive oxygen intermediates (ROIs)
    • Brandolini L et al. Carbocysteine lysine salt monohydrate (SCMC-LYS) is a selective scavenger of reactive oxygen intermediates (ROIs). Eur Cytokine Netw 2003; 14: 20-26.
    • (2003) Eur Cytokine Netw , vol.14 , pp. 20-26
    • Brandolini, L.1
  • 4
    • 33746663505 scopus 로고    scopus 로고
    • Non-classical drug metabolism enzymes: The curious case of phenylalanine 4-monooxygenase
    • Steventon GB, Mitchell SC. Non-classical drug metabolism enzymes: the curious case of phenylalanine 4-monooxygenase. Letts Drug Design Discov 2006; 3: 405-412.
    • (2006) Letts Drug Design Discov , vol.3 , pp. 405-412
    • Steventon, G.B.1    Mitchell, S.C.2
  • 5
    • 7444267297 scopus 로고    scopus 로고
    • Phenylalanine hydroxylase: Possible involvement in the S-oxidation of S-carboxymethyl-L-cysteine
    • Boonyapiwat B et al. Phenylalanine hydroxylase: possible involvement in the S-oxidation of S-carboxymethyl-L-cysteine. Anal Biochem 2004; 335: 91-97.
    • (2004) Anal Biochem , vol.335 , pp. 91-97
    • Boonyapiwat, B.1
  • 6
    • 23744490773 scopus 로고    scopus 로고
    • Phenylalanine 4-monooxygenase and the S-oxidation of S-carboxymethyl-L-cysteine in HepG2 cells
    • Boonyapiwat B et al. Phenylalanine 4-monooxygenase and the S-oxidation of S-carboxymethyl-L-cysteine in HepG2 cells. Drug Metab Drug Inter 2005; 21: 1-18.
    • (2005) Drug Metab Drug Inter , vol.21 , pp. 1-18
    • Boonyapiwat, B.1
  • 7
    • 6344255207 scopus 로고    scopus 로고
    • Phenylalanine 4-monooxygenase and the S-oxidation of S-carboxymethyl-L-cysteine
    • Goreish AH et al. Phenylalanine 4-monooxygenase and the S-oxidation of S-carboxymethyl-L-cysteine. Drug Metab Drug Inter 2004; 20: 159-174.
    • (2004) Drug Metab Drug Inter , vol.20 , pp. 159-174
    • Goreish, A.H.1
  • 8
    • 0345508199 scopus 로고    scopus 로고
    • Meese CD. S-Carboxymethyl-L-cysteine-(R)- und (S)-sulphoxid. Arch Pharm (Weinheim) 1987; 320: 473-474.
    • Meese CD. S-Carboxymethyl-L-cysteine-(R)- und (S)-sulphoxid. Arch Pharm (Weinheim) 1987; 320: 473-474.
  • 9
    • 0025607336 scopus 로고
    • Synthesis of metabolites of S-carboxymethyl- L-cysteine and S-methyl-L-cysteine and some isotopically labelled (2H, 13C) analogues
    • Meese CD et al. Synthesis of metabolites of S-carboxymethyl- L-cysteine and S-methyl-L-cysteine and some isotopically labelled (2H, 13C) analogues. Arch Pharm (Weinheim) 1990; 323: 957-965.
    • (1990) Arch Pharm (Weinheim) , vol.323 , pp. 957-965
    • Meese, C.D.1
  • 10
    • 0342840697 scopus 로고
    • The formation of mercapturic acids. 3. N-acetylation of S-substituted cysteines in the rabbit, rat and guinea pig
    • Bray HG et al. The formation of mercapturic acids. 3. N-acetylation of S-substituted cysteines in the rabbit, rat and guinea pig. Biochem J 1959; 73: 465-473.
    • (1959) Biochem J , vol.73 , pp. 465-473
    • Bray, H.G.1
  • 11
    • 0001116335 scopus 로고
    • Metabolism of some ω-halogenoalkylbenzenes and related alcohols in the rabbit
    • Bray HG et al. Metabolism of some ω-halogenoalkylbenzenes and related alcohols in the rabbit. Biochem J 1958; 70: 570-579.
    • (1958) Biochem J , vol.70 , pp. 570-579
    • Bray, H.G.1
  • 12
    • 0015085567 scopus 로고
    • The hydrolysis of thermolysin of dipeptide derivatives that contain substituted cysteine
    • Damoglou AP et al. The hydrolysis of thermolysin of dipeptide derivatives that contain substituted cysteine. Biochem J 1971; 123: 379-384.
    • (1971) Biochem J , vol.123 , pp. 379-384
    • Damoglou, A.P.1
  • 13
    • 0028901398 scopus 로고
    • Expression of recombinant human phenylalanine hydroxylase as fusion protein in Escherichia coli circumvents proteolytic degradation by host cell proteases
    • Martinez A et al. Expression of recombinant human phenylalanine hydroxylase as fusion protein in Escherichia coli circumvents proteolytic degradation by host cell proteases. Biochem J 1995; 306: 589-597.
    • (1995) Biochem J , vol.306 , pp. 589-597
    • Martinez, A.1
  • 14
    • 33845624501 scopus 로고    scopus 로고
    • Specific interaction of the diastereomers 7(R)- and 7(S)- tetrahydrobiopterin with phenylalanine hydroxylase: Implications for understanding primapterinuria and vitiligo
    • Pey AL et al. Specific interaction of the diastereomers 7(R)- and 7(S)- tetrahydrobiopterin with phenylalanine hydroxylase: Implications for understanding primapterinuria and vitiligo. FASEB J 2006; 20: E1451-E1464.
    • (2006) FASEB J , vol.20
    • Pey, A.L.1
  • 15
    • 0026075695 scopus 로고
    • Determination of S-carboxymethyl-L- cysteine and some of its metabolites in urine and serum by highperformance liquid chromatography using fluorescent precolumn labelling
    • Staffeldt B et al. Determination of S-carboxymethyl-L- cysteine and some of its metabolites in urine and serum by highperformance liquid chromatography using fluorescent precolumn labelling. J Chromatogr 1991; 571: 133-147.
    • (1991) J Chromatogr , vol.571 , pp. 133-147
    • Staffeldt, B.1
  • 16
    • 0030249197 scopus 로고    scopus 로고
    • Recombinant human phenylalanine hydroxylase: Novel regulatory and structural properties
    • Kowlessur D et al. Recombinant human phenylalanine hydroxylase: Novel regulatory and structural properties. Arch Biochem Biophys 1996; 333: 85-95.
    • (1996) Arch Biochem Biophys , vol.333 , pp. 85-95
    • Kowlessur, D.1
  • 17
    • 0030437749 scopus 로고    scopus 로고
    • Structure/function relationships in human phenylalanine hydroxylase. Effect of terminal deletions on the oligomerization, activation and cooperativity of substrate binding to the enzyme
    • Knappskog M et al. Structure/function relationships in human phenylalanine hydroxylase. Effect of terminal deletions on the oligomerization, activation and cooperativity of substrate binding to the enzyme. Eur J Biochem 1996; 242: 813-821.
    • (1996) Eur J Biochem , vol.242 , pp. 813-821
    • Knappskog, M.1
  • 18
    • 28844490531 scopus 로고    scopus 로고
    • Kinetic stability analysis of PKU mutations identified in BH4-responsive patients
    • Perez B et al. Kinetic stability analysis of PKU mutations identified in BH4-responsive patients. Mol Genet Metab 2005; 86: S11-S16.
    • (2005) Mol Genet Metab , vol.86
    • Perez, B.1
  • 19
    • 0024328662 scopus 로고
    • The deficiency of sulfoxidation of S-carboxymethyl-L-cysteine
    • Mitchell SC, Waring RH. The deficiency of sulfoxidation of S-carboxymethyl-L-cysteine. Pharmacol Ther 1989; 43: 237-249.
    • (1989) Pharmacol Ther , vol.43 , pp. 237-249
    • Mitchell, S.C.1    Waring, R.H.2
  • 20
    • 0020081938 scopus 로고
    • The metabolism and elimination of S-carboxymethyl-L-cysteine in man
    • Waring RH, Mitchell SC. The metabolism and elimination of S-carboxymethyl-L-cysteine in man. Drug Metab Dispos 1982; 10: 61-62.
    • (1982) Drug Metab Dispos , vol.10 , pp. 61-62
    • Waring, R.H.1    Mitchell, S.C.2
  • 21
    • 0022472862 scopus 로고
    • Cytosolic sulphoxidation of S-carboxymethyl- Lcysteine in mammals
    • Waring RH et al. Cytosolic sulphoxidation of S-carboxymethyl- Lcysteine in mammals. Biochem Pharmacol 1986; 35: 2999-3002.
    • (1986) Biochem Pharmacol , vol.35 , pp. 2999-3002
    • Waring, R.H.1
  • 22
    • 33745541339 scopus 로고    scopus 로고
    • Antithrombotic and anticancer effects of garlic-derived sulfur compounds: A review
    • Ariga T, Seki T. Antithrombotic and anticancer effects of garlic-derived sulfur compounds: a review. BioFactors 2006; 26: 93-103.
    • (2006) BioFactors , vol.26 , pp. 93-103
    • Ariga, T.1    Seki, T.2
  • 23
    • 33644843543 scopus 로고    scopus 로고
    • Preclinical perspectives on garlic and cancer
    • Milner JA. Preclinical perspectives on garlic and cancer. J Nutr 2006; 136: 827S-831S.
    • (2006) J Nutr , vol.136
    • Milner, J.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.