Effects of inherited mutations on catalytic activity and structural stability of human glucose-6-phosphate isomerase expressed in Escherichia coli

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1794, Issue 2, 2009, Pages 315-323

  Lin, Hua Yang ^a   Kao, Ya Heui ^a   Chen, Shu Ting ^a   Meng, Menghsiao ^a  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

Blue native PAGE; Glucose 6 phosphate isomerase; HNSHA; Nonspherocytic hemolytic anemia; Phosphoglucose isomerase; Thermostability

Indexed keywords

GLUCOSE 6 PHOSPHATE ISOMERASE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME ACTIVITY; ENZYME STABILITY; ENZYME STRUCTURE; ESCHERICHIA COLI; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PURIFICATION;

AMINO ACID SEQUENCE; ANEMIA, HEMOLYTIC; CATALYSIS; CATALYTIC DOMAIN; ENZYME STABILITY; ESCHERICHIA COLI; GLUCOSE-6-PHOSPHATE ISOMERASE; HUMANS; HYDROPHOBICITY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; RECOMBINANT PROTEINS;

ESCHERICHIA COLI; MAMMALIA;

EID: 58149193188     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2008.11.004     Document Type: Article

References (46)

1. Watanabe H., Takehana K., Date M., Shinozaki T., and Raz A. Tumor cell autocrine motility factor is the neuroleukin/phosphohexose isomerase polypeptide. Cancer Res. 56 (1996) 2960-2963
2. Liotta L.A., Mandler R., Murano G., Katz D.A., Gordon R.K., Chiang P.K., and Schiffmann E. Tumor cell autocrine motility factor. Proc. Nat. Acad. Sci. U. S. A. 83 (1986) 3302-3306
3. Baumann M., and Brand K. Purification and characterization of phosphohexose isomerase from human gastrointestinal carcinoma and its potential relationship to neuroleukin. Cancer Res. 48 (1988) 7018-7021
4. Baumann M., Kappl A., Lang T., Brand K., Siegfried W., and Paterok E. The diagnostic validity of the serum tumor marker phosphohexose isomerase (PHI) in patients with gastrointestinal, kidney, and breast cancer. Cancer Invest. 8 (1990) 351-356
5. Filella X., Molina R., Jo J., Mas E., and Ballesta A.M. Serum phosphohexose isomerase activities in patients with colorectal cancer. Tumour Biol. 12 (1991) 360-367
6. Patel P.S., Raval G.N., Rawal R.M., Patel G.H., Balar D.B., Shah P.M., and Patel D.D. Comparison between serum levels of carcinoembryonic antigen, sialic acid and phosphohexose isomerase in lung cancer. Neoplasma 42 (1995) 271-274
7. Shimizu K., Tani M., Watanabe H., Nagamachi Y., Niinaka Y., Shiroishi T., Ohwada S., Raz A., and Yokota J. The autocrine motility factor receptor gene encodes a novel type of seven transmembrane protein. FEBS Lett. 456 (1999) 295-300
8. Tsutsumi S., Gupta S.K., Hogan V., Collard J.G., and Raz A. Activation of small GTPase Rho is required for autocrine motility factor signaling. Cancer Res. 62 (2002) 4484-4490
9. Yu F.L., Liao M.H., Lee J.W., and Shih W.L. Induction of hepatoma cells migration by phosphoglucose isomerase/autocrine motility factor through the upregulation of matrix metalloproteinase-3. Biochem. Biophys. Res. Commun. 314 (2004) 76-82
10. Chaput M., Claes V., Portetelle D., Cludts I., Cravador A., Burny A., Gras H., and Tartar A. The neurotrophic factor neuroleukin is 90% homologous with phosphohexose isomerase. Nature 332 (1988) 454-455
11. Xu W., Seiter K., Feldman E., Ahmed T., and Chiao J.W. The differentiation and maturation mediator for human myeloid leukemia cells shares homology with neuroleukin or phosphoglucose isomerase. Blood 87 (1996) 4502-4506
12. Matsumoto I., Staub A., Benoist C., and Mathis D. Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme. Science 286 (1999) 1732-1735
13. Schubert D., Maier B., Morawietz L., Krenn V., and Kamradt T. Immunization with glucose-6-phosphate isomerase induces T cell-dependent peripheral polyarthritis in genetically unaltered mice. J. Immunol. 172 (2004) 4503-4509
14. Bockermann R., Schubert D., Kamradt T., and Holmdahl R. Induction of a B-cell-dependent chronic arthritis with glucose-6-phosphate isomerase. Arthritis Res. Ther. 7 (2005) R1316-1324
15. Schaller M., Burton D.R., and Ditzel H.J. Autoantibodies to GPI in rheumatoid arthritis: linkage between an animal model and human disease. Nat. Immunol. 2 (2001) 746-753
16. Schubert D., Schmidt M., Zaiss D., Jungblut P.R., and Kamradt T. Autoantibodies to GPI and creatine kinase in RA. Nat. Immunol. 3 (2002) 411 author reply 412-413
17. Kassahn D., Kolb C., Solomon S., Bochtler P., and Illges H. Few human autoimmune sera detect GPI. Nat. Immunol. 3 (2002) 411-412 author reply 412-413
18. Matsumoto I., Lee D.M., Goldbach-Mansky R., Sumida T., Hitchon C.A., Schur P.H., Anderson R.J., Coblyn J.S., Weinblatt M.E., Brenner M., Duclos B., Pasquali J.L., El-Gabalawy H., Mathis D., and Benoist C. Low prevalence of antibodies to glucose-6-phosphate isomerase in patients with rheumatoid arthritis and a spectrum of other chronic autoimmune disorders. Arthritis Rheum. 48 (2003) 944-954
19. Schaller M., Stohl W., Tan S.M., Benoit V.M., Hilbert D.M., and Ditzel H.J. Raised levels of anti-glucose-6-phosphate isomerase IgG in serum and synovial fluid from patients with inflammatory arthritis. Ann. Rheum. Dis. 64 (2005) 743-749
20. Kugler W., and Lakomek M. Glucose-6-phosphate isomerase deficiency. Baillieres's Best Pract. Res., Clin. Haematol. 13 (2000) 89-101
21. Baughan M.A., Valentine W.N., Paglia D.E., Ways P.O., Simons E.R., and DeMarsh Q.B. Hereditary hemolytic anemia associated with glucosephosphate isomerase (GPI) deficiency-a new enzyme defect of human erythrocytes. Blood 32 (1968) 236-249
22. Neubauer B.A., Eber S.W., Lakomek M., Gahr M., and Schroter W. Combination of congenital nonspherocytic haemolytic anaemia and impairment of granulocyte function in severe glucosephosphate isomerase deficiency. A new variant enzyme designated GPI Calden. Acta haematol. 83 (1990) 206-210
23. Huppke P., Wunsch D., Pekrun A., Kind R., Winkler H., Schroter W., and Lakomek M. Glucose phosphate isomerase deficiency: biochemical and molecular genetic studies on the enzyme variants of two patients with severe haemolytic anaemia. Eur. J. Pediatr. 156 (1997) 605-609
24. Lakomek M., and Winkler H. Erythrocyte pyruvate kinase- and glucose phosphate isomerase deficiency: perturbation of glycolysis by structural defects and functional alterations of defective enzymes and its relation to the clinical severity of chronic hemolytic anemia. Biophys. Chem. 66 (1997) 269-284
25. Kugler W., Breme K., Laspe P., Muirhead H., Davies C., Winkler H., Schroter W., and Lakomek M. Molecular basis of neurological dysfunction coupled with haemolytic anaemia in human glucose-6-phosphate isomerase (GPI) deficiency. Hum. Genet. 103 (1998) 450-454
26. Repiso A., Oliva B., Vives Corrons J.L., Carreras J., and Climent F. Glucose phosphate isomerase deficiency: enzymatic and familial characterization of Arg346His mutation. Biochim. Biophys. Acta 1740 (2005) 467-471
27. Repiso A., Oliva B., Vives-Corrons J.L., Beutler E., Carreras J., and Climent F. Red cell glucose phosphate isomerase (GPI): a molecular study of three novel mutations associated with hereditary nonspherocytic hemolytic anemia. Hum. Mutat. 27 (2006) 1159
28. Kanno H., Fujii H., and Miwa S. Expression and enzymatic characterization of human glucose phosphate isomerase (GPI) variants accounting for GPI deficiency. Blood Cells Mol. Dis. 24 (1998) 54-61
29. Read J., Pearce J., Li X., Muirhead H., Chirgwin J., and Davies C. The crystal structure of human phosphoglucose isomerase at 1.6 A resolution: implications for catalytic mechanism, cytokine activity and haemolytic anaemia. J. Mol. Biol. 309 (2001) 447-463
30. Cordeiro A.T., Godoi P.H., Silva C.H., Garratt R.C., Oliva G., and Thiemann O.H. Crystal structure of human phosphoglucose isomerase and analysis of the initial catalytic steps. Biochim. Biophys. Acta 1645 (2003) 117-122
31. Davies C., Muirhead H., and Chirgwin J. The structure of human phosphoglucose isomerase complexed with a transition-state analogue. Acta Crystallographica 59 (2003) 1111-1113
32. Chou C.C., Sun Y.J., Meng M., and Hsiao C.D. The crystal structure of phosphoglucose isomerase/autocrine motility factor/neuroleukin complexed with its carbohydrate phosphate inhibitors suggests its substrate/receptor recognition. J. Biol. Chem. 275 (2000) 23154-23160
33. Lee J.H., Chang K.Z., Patel V., and Jeffery C.J. Crystal structure of rabbit phosphoglucose isomerase complexed with its substrate d-fructose 6-phosphate. Biochemistry 40 (2001) 7799-7805
34. Davies C., and Muirhead H. Crystal structure of phosphoglucose isomerase from pig muscle and its complex with 5-phosphoarabinonate. Proteins 49 (2002) 577-579
35. Graham Solomons J.T., Zimmerly E.M., Burns S., Krishnamurthy N., Swan M.K., Krings S., Muirhead H., Chirgwin J., and Davies C. The crystal structure of mouse phosphoglucose isomerase at 1.6 A resolution and its complex with glucose 6-phosphate reveals the catalytic mechanism of sugar ring opening. J. Mol. Biol. 342 (2004) 847-860
36. Dische Z., and Borenfreund E. A new spectrophotometric method for the detection and determination of keto sugars and trioses. J. Biol. Chem. 192 (1951) 583-587
37. Schagger H., Cramer W.A., and von Jagow G. Analysis of molecular masses and oligomeric states of protein complexes by blue native electrophoresis and isolation of membrane protein complexes by two-dimensional native electrophoresis. Anal. Biochem. 217 (1994) 220-230
38. Meng M., Chen Y.T., Hsiao Y.Y., Itoh Y., and Bagdasarian M. Mutational analysis of the conserved cationic residues of Bacillus stearothermophilus 6-phosphoglucose isomerase. Eur. J. Biochem. 257 (1998) 500-505
39. Meng M., Chane T.L., Sun Y.J., and Hsiao C.D. Probing the location and function of the conserved histidine residue of phosphoglucose isomerase by using an active site directed inhibitor N-bromoacetylethanolamine phosphate. Protein Sci. 8 (1999) 2438-2443
40. Tsuboi K.K., Fukunaga K., and Chervenka C.H. Phosphoglucose isomerase from human erythrocyte. Preparation and properties. J. Biol. Chem. 246 (1971) 7586-7594
41. Paglia D.E., and Valentine W.N. Hereditary glucosephosphate isomerase deficiency. A review. Am. J. Clin. Pathol. 62 (1974) 740-751
42. Fujii H., Kanno H., Hirono A., and Miwa S. Hematologically important mutations: molecular abnormalities of glucose phosphate isomerase deficiency. Blood Cells Mol. Dis. 22 (1996) 96-97
43. Xu W., and Beutler E. The characterization of gene mutations for human glucose phosphate isomerase deficiency associated with chronic hemolytic anemia. J. Clin. Invest. 94 (1994) 2326-2329
44. Baronciani L., Zanella A., Bianchi P., Zappa M., Alfinito F., Iolascon A., Tannoia N., Beutler E., and Sirchia G. Study of the molecular defects in glucose phosphate isomerase-deficient patients affected by chronic hemolytic anemia. Blood 88 (1996) 2306-2310
45. Beutler E., West C., Britton H.A., Harris J., and Forman L. Glucosephosphate isomerase (GPI) deficiency mutations associated with hereditary nonspherocytic hemolytic anemia (HNSHA). Blood Cells Mol. Dis. 23 (1997) 402-409
46. Vieille C., and Zeikus G.J. Hyperthermophilic enzymes: sources, uses, and molecular mechanisms for thermostability. Microbiol. Mol. Biol. Rev. 65 (2001) 1-43