The crystal structure of human phosphoglucose isomerase at 1.6 Å resolution: Implications for catalytic mechanism, cytokine activity and haemolytic anaemia

Journal of Molecular Biology

Volumn 309, Issue 2, 2001, Pages 447-463

  Read, Jon ^a   Pearce, Jake ^b   Li, Xiaochun ^c   Muirhead, Hilary ^a   Chirgwin, John ^c   Davies, Christopher ^b  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF SUSSEX   (United Kingdom)

^c UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

Author keywords

Aldose ketose isomerases; Cytokine; Haemolytic anaemia; Neuroleukin; X ray crystallography

Indexed keywords

CYTOKINE; GLUCOSE 6 PHOSPHATE ISOMERASE;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME STRUCTURE; GENE MAPPING; GENE MUTATION; HEMOLYTIC ANEMIA; HUMAN; HUMAN CELL; PRIORITY JOURNAL; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

ORYCTOLAGUS CUNICULUS;

EID: 0035369540     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4680     Document Type: Article

References (70)

1. Mechanism of the aldose-ketose isomerase reactions
2. The effect of pH and temperature on the kinetic parameters of phosphoglucose isomerase. Participation of histidine and lysine in a proposed dual function mechanism
3. The crystal structure of a multifunctional protein: Phosphoglucose isomerase/autocrine motility factor/neuroleukin
4. Crystal structure of rabbit phosphoglucose isomerase, a glycolytic enzyme that moonlights as neuroleukin, autocrine motility factor, and differentiation mediator
5. Molecular cloning and expression of neuroleukin, a neurotrophic factor for spinal and sensory neurons
6. Tumor cell autocrine motility factor is the neuroleukin/phosphohexose isomerase polypeptide
7. The differentiation and maturation mediator for human myeloid leukemia cells shares homology with neuroleukin or phosphoglucose isomerase
8. Purification of a novel serine proteinase inhibitor from the skeletal muscle of white croaker (Argyrosomus argentatus)
9. Moonlighting proteins
10. Neuroleukin: A lymphokine product of lectin-stimulated T cells
11. The diagnostic validity of the serum tumor marker phosphohexose isomerase (PHI) in patients with gastrointestinal, kidney, and breast cancer
12. Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme
13. Cloning of a glucose phosphate isomerase/neuroleukin-like sperm antigen involved in sperm agglutination
14. Biochemical characteristics of a human myeloid leukemia differentiation factor
15. Purification of human tumor cell autocrine motility factor and molecular cloning of its receptor
16. Matrix-bound phosphoglucose isomerase. Formation and properties of monomers and hybrids
17. The crystal structure of phosphoglucose isomerase/autocrine motility factor/neuroleukin complexed with its carbohydrate phosphate inhibitors suggests its substrate/receptor recognition
18. Hereditary hemolytic anemia associated with glucosephosphate isomerase (GPI) deficiency-a new enzyme defect of human erythrocytes
19. Glucose-6-phosphate isomerase deficiency
20. X-ray diffraction studies on enzymes in the glycolytic pathway
21. Crystallographic structure analysis of glucose 6-phosphate isomerase at 3.5 Å resolution
22. Glucose 6-phosphate isomerase
23. Solvent content of protein crystals
24. Conformational states of native and denatured phosphoglucose isomerase. I. Ultra violet difference spectroscopy
25. Physical studies on the subunit structure of rabbit muscle phosphoglucose isomerase
26. The active site of glucose phosphate isomerase
27. Aldose-ketose isomerases
28. Phosphoglucoisomerase-catalyzed interconversion of hexose phosphates: Isotopic discrimination between hydrogen and deuterium
29. On the mechanism of action of phosphoglucose isomerase and phosphomannose isomerase
30. The enediolate analogue 5-phosphoarabinonate as a mechanistic probe for phosphoglucose isomerase
31. Proportion of keto and aldehyde forms in solutions of sugars and sugar phosphates
32. Mannose 6-phosphate: Anomeric form used by phosphomannose isomerase and its 1-epimerization by phosphoglucose isomerase
33. Chemical modification of critical catalytic residues of lysine, arginine, and tryptophan in human glucose phosphate isomerase
34. Isolation and sequence determination of two pyridoxal 5′-phosphate-labeled thermolysin peptides from pig muscle phosphoglucose isomerase
35. Arginine-specific modification of rabbit muscle phosphoglucose isomerase: Differences in the inactivation by phenylglyoxal and butanedione and in the protection by substrate analogues
36. Affinity labeling and characterization of the active site histidine of glucosephosphate isomerase. Sequence homology with triosephosphate isomerase
37. Affinity labeling of phosphoglucose isomerase by 1,2-anhydrohexitol-6-phosphates
38. Electrophilic catalysis in triosephosphate isomerase: The role of histidine-95
39. Probing the location and function of the conserved histidine residue of phosphoglucose isomerase by using an active site directed inhibitor N-bromoacetylethanolamine phosphate
40. Molecular basis of neurological dysfunction coupled with haemolytic anaemia in human glucose-6-phosphate isomerase (GPI) deficiency
41. A genetically defined animal model of anembryonic pregnancy
42. Death of mouse embryos that lack a functional gene for glucose phosphate isomerase
43. Tumor cell autocrine motility factor
44. Expression of autocrine motility factor/phosphohexose isomerase in Cos7 cells
45. Phosphohexose isomerase/autocrine motility factor/neuroleukin. Maturation factor is a multifunctional phosphoprotein
46. The autocrine motility factor receptor gene encodes a novel type of seven transmembrane protein
47. The neurotrophic factor neuroleukin is 90% homologous with phosphohexose isomerase
48. Clathrin-mediated endocytosis and recycling of autocrine motility factor receptor to fibronectin fibrils is a limiting factor for NIH-3T3 cell motility
49. Unusual routes of protein secretion: The easy way out
50. Rabbit phosphoglucose isomerase/neuroleukin/autocrine motility factor: Cloning via interspecies identity
51. Processing of X-ray diffraction data collected in oscillation mode
52. Improved methods for building protein structures in electron-density maps and the location of errors in these models
53. Refinement of macromolecular structures by the maximum-likelihood method
54. Automated refinement of protein models
55. Chemical studies on the subunit structure of rabbit muscle phosphoglucose isomerase
56. Identification of a novel tandemly repeated sequence present in an intron of the glucose phosphate isomerase (GPI) gene in mouse and man
57. Characterization of the 5′ end of the gene for human glucose phosphate isomerase (GPI)
58. Cloning and structural analysis of complementary DNA of the human neuroleukin gene
59. The CCP4 suite: Programs for protein crystallography
60. An extensively modified version of Molscript that includes greatly enhanced coloring capabilities
61. MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
62. PROMOTIF - A program to identify and analyze structural motifs in proteins
63. Molecular analysis of glucose phosphate isomerase deficiency associated with hereditary hemolytic anemia
64. Glucosephosphate isomerase (GPI) deficiency mutations associated with hereditary nonspherocytic hemolytic anemia (HNSHA)
65. An exonic polymorphism in the human glucose phosphate isomerase (GPI) gene
66. Study of the molecular defects in glucose phosphate isomerase-deficient patients affected by chronic hemolytic anemia
67. DNA sequence abnormalities in human glucose 6-phosphate isomerase deficiency
68. Glucose phosphate isomerase deficiency: Biochemical and molecular genetic studies on the enzyme variants of two patients with severe haemolytic anaemia