Oral absorption enhancement of dipeptide L-Glu-L-Trp-OH by lipid and glycosyl conjugation

Biopolymers - Peptide Science Section

Volumn 90, Issue 5, 2008, Pages 633-643

  Bergeon, Julie A ^a   Chan, Yiu Ngok ^a   Charles, Bruce G ^a   Toth, Istvan ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Glycosyl conjugation; Lipid conjugation; Peptide oral absorption

Indexed keywords

ABSORPTION RATES; CELLOBIOSE; D-GLUCURONIC ACIDS; DIPEPTIDE; DODECANOIC ACIDS; ENZYMATIC DEGRADATIONS; GLYCOSYL CONJUGATION; HAEMOLYSIS; IN-VIVO EXPERIMENTS; MEMBRANE PERMEABILITIES; RED BLOOD CELLS; SOLID-PHASE PEPTIDE SYNTHESIS; SUGAR MOIETIES; WISTAR RATS;

ABSORPTION; ACIDS; AMINATION; BIOCHEMISTRY; BIOLOGICAL MEMBRANES; BLOOD; CAPILLARITY; CYTOLOGY; DERIVATIVES; ENZYMATIC HYDROLYSIS; FATTY ACIDS; GLUCOSE; HYDROLYSIS; PEPTIDES; RESINS; SUGAR (SUCROSE); SYNTHESIS (CHEMICAL);

AMINES;

ALPHA GLUTAMYLTRYPTOPHAN; ALPHA-GLUTAMYLTRYPTOPHAN; DIPEPTIDE; GLUCOSE; LIPID; THYMOGEN; UNCLASSIFIED DRUG;

ABSORPTION; ANIMAL; ARTICLE; CELL CULTURE; CELL STRAIN CACO 2; CHEMISTRY; DRUG EFFECT; DRUG POTENTIATION; GLYCOSYLATION; HEMOLYSIS; HUMAN; MALE; METABOLISM; MOUTH; ORAL DRUG ADMINISTRATION; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; WISTAR RAT;

ABSORPTION; ADMINISTRATION, ORAL; ANIMALS; CACO-2 CELLS; CELLS, CULTURED; DIPEPTIDES; DRUG SYNERGISM; GLUCOSE; GLYCOSYLATION; HEMOLYSIS; HUMANS; LIPIDS; MALE; MOUTH; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR;

EID: 58149188737     PISSN: 00063525     EISSN: 10970282     Source Type: Journal    
DOI: 10.1002/bip.21003     Document Type: Conference Paper

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