Synthesis and in vitro evaluation of lipoamino acid and carbohydrate-modified enkephalins as potential antinociceptive agents

International Journal of Pharmaceutics

Volumn 161, Issue 1, 1998, Pages 55-64

  Kellam, Barrie ^a   Drouillat, Bruno ^a   Dekany, Gyula ^a   Starr, Mike S ^a   Toth, Istvan ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Blood brain barrier; Drug delivery; Enkephalins; Glycopeptides; Lipoamino acids; Solid phase peptide synthesis

Indexed keywords

AMINO ACID; ANTINOCICEPTIVE AGENT; DELTA OPIATE RECEPTOR; ENKEPHALIN; GLUCURONIC ACID;

ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG SYNTHESIS; GUINEA PIG; ILEUM; LIPOPHILICITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; VAS DEFERENS;

EID: 0032498638     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(97)00328-1     Document Type: Article

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