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Volumn 877, Issue 3, 2009, Pages 141-148
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Investigating the in vitro metabolism of veratridine: Characterization of metabolites and involved cytochrome P450 isoforms
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Author keywords
Cytochrome P450; Metabolites; Microsome; Veratridine
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Indexed keywords
APOPTOSIS;
CYTOCHROME P450;
IN VITRO;
IN-VIVO;
ION TRAP TANDEM MASS SPECTROMETRIES;
ISOFORMS;
MICROSOME;
NEURONAL CELLS;
NEUROTOXICITY;
RAT LIVER MICROSOMES;
RECEPTOR SITES;
SODIUM IONS;
VERATRIDINE;
BINDING SITES;
BIOCHEMISTRY;
BIOMOLECULES;
CELL DEATH;
CHROMATOGRAPHIC ANALYSIS;
ELECTROSPRAY IONIZATION;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
ION CHROMATOGRAPHY;
IONIZATION OF LIQUIDS;
LIQUID CHROMATOGRAPHY;
LIVER;
MASS SPECTROMETERS;
MASS SPECTROMETRY;
METABOLISM;
METAL IONS;
QUANTUM OPTICS;
METABOLITES;
CYTOCHROME P450 1A;
CYTOCHROME P450 2B;
CYTOCHROME P450 2E1;
CYTOCHROME P450 3A;
DRUG METABOLITE;
VERATRIDINE;
ANIMAL TISSUE;
ARTICLE;
DRUG METABOLISM;
DRUG STRUCTURE;
ELECTROSPRAY MASS SPECTROMETRY;
IN VITRO STUDY;
LIQUID CHROMATOGRAPHY;
LIVER MICROSOME;
MALE;
NONHUMAN;
PRIORITY JOURNAL;
RAT;
ANIMALS;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
CYTOCHROME P-450 CYP1A1;
CYTOCHROME P-450 CYP2E1;
CYTOCHROME P-450 CYP3A;
CYTOCHROME P-450 ENZYME SYSTEM;
ENZYME INHIBITORS;
ISOENZYMES;
MALE;
MICROSOMES, LIVER;
RATS;
RATS, SPRAGUE-DAWLEY;
SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;
VERATRIDINE;
LILIACEAE;
RATTUS;
VERATRUM;
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EID: 58149181325
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2008.11.041 Document Type: Article |
Times cited : (11)
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References (29)
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