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Volumn 33, Issue 5, 2008, Pages 1055-1064

Protein kinase a serves as a primary pathway in activation of Nur77 expression by gonadotropin-releasing hormone in the LβT2 mouse pituitary gonadotroph tumor cell line

Author keywords

Cancer; Gonadotropin releasing hormone signaling; L T2; Nur77; Pituitary; Protein kinase A; Protein kinase C

Indexed keywords

8 BROMO CYCLIC AMP; CALCIUM; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; EGTAZIC ACID; FORSKOLIN; GONADORELIN; GONADORELIN DERIVATIVE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NUCLEAR RECEPTOR NUR77; PROTEIN KINASE C; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; CHELATING AGENT; DNA BINDING PROTEIN; DRUG DERIVATIVE; ENZYME ACTIVATOR; LHRH, ALA(6) GLY(10) ETHYLAMIDE; LHRH, ALA(6)-GLY(10)-ETHYLAMIDE-; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE INHIBITOR; STEROID RECEPTOR; UNCLASSIFIED DRUG;

EID: 58149176620     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000094     Document Type: Article
Times cited : (27)

References (94)
  • 1
    • 0027074637 scopus 로고
    • Identification of a new brain-specific transcription factor, NURR1
    • Law SW, Conneely OM, DeMayo FJ and O'Malley BW: Identification of a new brain-specific transcription factor, NURR1. Mol Endocrinol 6: 2129-2135, 1992.
    • (1992) Mol Endocrinol , vol.6 , pp. 2129-2135
    • Law, S.W.1    Conneely, O.M.2    DeMayo, F.J.3    O'Malley, B.W.4
  • 2
    • 0028606279 scopus 로고
    • Molecular cloning of a novel thyroid/steroid receptor superfamily gene from cultured rat neuronal cells
    • Ohkura N, Hijikuro M, Yamamoto A and Miki K: Molecular cloning of a novel thyroid/steroid receptor superfamily gene from cultured rat neuronal cells. Biochem Biophys Res Commun 205: 1959-1965, 1994.
    • (1994) Biochem Biophys Res Commun , vol.205 , pp. 1959-1965
    • Ohkura, N.1    Hijikuro, M.2    Yamamoto, A.3    Miki, K.4
  • 3
    • 0024002468 scopus 로고
    • Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene
    • Milbrandt J: Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene. Neuron 1: 183-188, 1988.
    • (1988) Neuron , vol.1 , pp. 183-188
    • Milbrandt, J.1
  • 4
    • 0001479498 scopus 로고
    • A gene inducible by serum growth factors encodes a member of the steroid and thyroid hormone receptor superfamily
    • Hazel TG, Nathans D and Lau LF: A gene inducible by serum growth factors encodes a member of the steroid and thyroid hormone receptor superfamily. Proc Natl Acad Sci USA 85: 8444-8448, 1988.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 8444-8448
    • Hazel, T.G.1    Nathans, D.2    Lau, L.F.3
  • 5
    • 0025200728 scopus 로고
    • The NGF-1B protein, and inducible member of the thyroid/steroid receptor family, is rapidly modified posttranslationally
    • Fahrner TJ, Carroll SL and Milbrandt J: The NGF-1B protein, and inducible member of the thyroid/steroid receptor family, is rapidly modified posttranslationally. Mol Cell Biol 10: 6454-6459, 1990.
    • (1990) Mol Cell Biol , vol.10 , pp. 6454-6459
    • Fahrner, T.J.1    Carroll, S.L.2    Milbrandt, J.3
  • 6
    • 23844468795 scopus 로고    scopus 로고
    • Induction of NR4A orphan receptor expression in macrophages in response to inflammatory stimuli
    • Pei L, Castrillo A, Chen M, Hoffmann A and Tontonoz P: Induction of NR4A orphan receptor expression in macrophages in response to inflammatory stimuli. J biol Chem 280: 29256-29262, 2005.
    • (2005) J biol Chem , vol.280 , pp. 29256-29262
    • Pei, L.1    Castrillo, A.2    Chen, M.3    Hoffmann, A.4    Tontonoz, P.5
  • 7
    • 1842636772 scopus 로고    scopus 로고
    • Nur77 induction and activation are necessary for interleukin-1 stimulation of proopiomelanocortin in AtT-20 corticotrophs
    • Kovalovsky D, Paez Pereda M, Labeur M, Renner U, Holsboer F, Stalla GK and Arzt E: Nur77 induction and activation are necessary for interleukin-1 stimulation of proopiomelanocortin in AtT-20 corticotrophs. FEBS Lett 563: 229-233, 2004.
    • (2004) FEBS Lett , vol.563 , pp. 229-233
    • Kovalovsky, D.1    Paez Pereda, M.2    Labeur, M.3    Renner, U.4    Holsboer, F.5    Stalla, G.K.6    Arzt, E.7
  • 8
    • 0345451557 scopus 로고
    • Activation by thyroid stimulating hormone of nerve growth factor-induced gene-B expression in thyrocytes in culture: Relation with proliferation and specific gene expression
    • Jimenez-Cervantes C, Pichon B, Dumont JE and Maenhaut C: Activation by thyroid stimulating hormone of nerve growth factor-induced gene-B expression in thyrocytes in culture: relation with proliferation and specific gene expression. Biochim Biophys Acta 1403: 232-244, 1988.
    • (1988) Biochim Biophys Acta , vol.1403 , pp. 232-244
    • Jimenez-Cervantes, C.1    Pichon, B.2    Dumont, J.E.3    Maenhaut, C.4
  • 10
    • 0035206446 scopus 로고    scopus 로고
    • LH induces orphan nuclear receptor Nur77 gene expression in testicular Leydig cells
    • Song KH, Park JI, Lee MO, Soh J, Lee K and Choi HS: LH induces orphan nuclear receptor Nur77 gene expression in testicular Leydig cells. Endocrinology 142: 5116-5123, 2001.
    • (2001) Endocrinology , vol.142 , pp. 5116-5123
    • Song, K.H.1    Park, J.I.2    Lee, M.O.3    Soh, J.4    Lee, K.5    Choi, H.S.6
  • 11
    • 21644456253 scopus 로고    scopus 로고
    • Activation of Nur77 by selected 1,1-Bis(3′-indolyl)-1-(p-substituted phenyl)methanes induces apoptosis through nuclear pathways
    • Chintharlapalli S, Burghardt R, Papineni S, Ramaiah S, Yoon K and Safe S: Activation of Nur77 by selected 1,1-Bis(3′-indolyl)-1-(p-substituted phenyl)methanes induces apoptosis through nuclear pathways. J Biol Chem 280: 24903-24914, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 24903-24914
    • Chintharlapalli, S.1    Burghardt, R.2    Papineni, S.3    Ramaiah, S.4    Yoon, K.5    Safe, S.6
  • 12
    • 3543119042 scopus 로고    scopus 로고
    • The atypical orphan nuclear receptor DAX-1 interacts with orphan nuclear receptor Nur77 and represses its transactivation
    • Song KH, Park, YY, Park KC, Hong CY, Park JH, Shong M, Lee K and Choi HS: The atypical orphan nuclear receptor DAX-1 interacts with orphan nuclear receptor Nur77 and represses its transactivation. Mol Endocrinol 18: 1929-1940, 2004.
    • (2004) Mol Endocrinol , vol.18 , pp. 1929-1940
    • Song, K.H.1    Park, Y.Y.2    Park, K.C.3    Hong, C.Y.4    Park, J.H.5    Shong, M.6    Lee, K.7    Choi, H.S.8
  • 13
    • 84995867020 scopus 로고
    • Ordered binding of retinoic acid and retinoid-X receptors to asymmetric response elements involves determinants adjacent to the DNA-binding domain
    • Predki PF, Zamble D, Sarkar B and Giguere V: Ordered binding of retinoic acid and retinoid-X receptors to asymmetric response elements involves determinants adjacent to the DNA-binding domain. Mol Endocrinol 8: 31-39, 1994.
    • (1994) Mol Endocrinol , vol.8 , pp. 31-39
    • Predki, P.F.1    Zamble, D.2    Sarkar, B.3    Giguere, V.4
  • 14
    • 0034192212 scopus 로고    scopus 로고
    • Retinoic acid and its receptors repress the expression and transactivation functions of Nur77: A possible mechanism for the inhibition of apoptosis by retinoic acid
    • Kang HJ, Song MR, Lee SK, Shin EC, Choi YH, Kim SJ, Lee JW and Lee MO: Retinoic acid and its receptors repress the expression and transactivation functions of Nur77: a possible mechanism for the inhibition of apoptosis by retinoic acid. Exp Cell Res 256: 545-554, 2000.
    • (2000) Exp Cell Res , vol.256 , pp. 545-554
    • Kang, H.J.1    Song, M.R.2    Lee, S.K.3    Shin, E.C.4    Choi, Y.H.5    Kim, S.J.6    Lee, J.W.7    Lee, M.O.8
  • 15
    • 0037198670 scopus 로고    scopus 로고
    • Promyelocytic leukemia protein PML inhibits Nur77-mediated transcription through specific functional interactions
    • Wu WS, Xu ZX, Ran R, Meng F and Chang KS: Promyelocytic leukemia protein PML inhibits Nur77-mediated transcription through specific functional interactions. Oncogene 21: 3925-3933, 2002.
    • (2002) Oncogene , vol.21 , pp. 3925-3933
    • Wu, W.S.1    Xu, Z.X.2    Ran, R.3    Meng, F.4    Chang, K.S.5
  • 16
    • 0037306094 scopus 로고    scopus 로고
    • Maira M, Martens C, Batsche E, Gauthier Y and Drouin J: Dimer-specific potentiation of NGFI-B (Nur77) transcriptional activity by the protein kinase A pathway and AF-1-dependent coactivator recruitment. Mol Cell Biol 23: 763-776, 2003.
    • Maira M, Martens C, Batsche E, Gauthier Y and Drouin J: Dimer-specific potentiation of NGFI-B (Nur77) transcriptional activity by the protein kinase A pathway and AF-1-dependent coactivator recruitment. Mol Cell Biol 23: 763-776, 2003.
  • 17
    • 0035941288 scopus 로고    scopus 로고
    • Silencing mediator of retinoid and thyroid hormone receptors and activating signal cointegrator-2 as transcriptional coregulators of the orphan nuclear receptor Nur77
    • Sohn YC, Kwak E, Na Y, Lee JW and Lee SK: Silencing mediator of retinoid and thyroid hormone receptors and activating signal cointegrator-2 as transcriptional coregulators of the orphan nuclear receptor Nur77. J Biol Chem 276: 43734-43739, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 43734-43739
    • Sohn, Y.C.1    Kwak, E.2    Na, Y.3    Lee, J.W.4    Lee, S.K.5
  • 18
    • 0027446362 scopus 로고
    • The orphan nuclear receptor NGFI-B regulates expression of the gene encoding steroid 21-hydroxylase
    • Wilson TE, Mouw AR, Weaver CA, Milbrandt J and Parker KL: The orphan nuclear receptor NGFI-B regulates expression of the gene encoding steroid 21-hydroxylase. Mol Cell Biol 13: 861-868, 1993.
    • (1993) Mol Cell Biol , vol.13 , pp. 861-868
    • Wilson, T.E.1    Mouw, A.R.2    Weaver, C.A.3    Milbrandt, J.4    Parker, K.L.5
  • 19
    • 0029071860 scopus 로고
    • Adrenocortical function and regulation of the steroid 21-hydroxylase gene in NGFI-B-deficient mice
    • Crawford PA, Sadovsky Y, Woodson K, Lee SL and Milbrandt J: Adrenocortical function and regulation of the steroid 21-hydroxylase gene in NGFI-B-deficient mice. Mol Cell Biol 15: 4331-4336, 1995.
    • (1995) Mol Cell Biol , vol.15 , pp. 4331-4336
    • Crawford, P.A.1    Sadovsky, Y.2    Woodson, K.3    Lee, S.L.4    Milbrandt, J.5
  • 20
    • 0034455587 scopus 로고    scopus 로고
    • Nuclear receptors Nor1 and NGFI-B/Nur77 play similar, albeit distinct, roles in the hypothalamo-pituitary-adrenal axis
    • Fernandez PM, Brunel F, Jimenez MA, Saez, JM, Cereghini S and Zakin MM: Nuclear receptors Nor1 and NGFI-B/Nur77 play similar, albeit distinct, roles in the hypothalamo-pituitary-adrenal axis. Endocrinology 141: 2392-2400, 2000.
    • (2000) Endocrinology , vol.141 , pp. 2392-2400
    • Fernandez, P.M.1    Brunel, F.2    Jimenez, M.A.3    Saez, J.M.4    Cereghini, S.5    Zakin, M.M.6
  • 21
    • 0034711188 scopus 로고    scopus 로고
    • Prostaglandin F2alpha-induced expression of 20alpha-hydroxysteroid dehydrogenase involves the transcription factor NUR77
    • Stocco CO, Zhong L, Sugimoto Y, Ichikawa A, Lau LF and Gibori G: Prostaglandin F2alpha-induced expression of 20alpha-hydroxysteroid dehydrogenase involves the transcription factor NUR77. J Biol Chem 275: 37202-37211, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 37202-37211
    • Stocco, C.O.1    Zhong, L.2    Sugimoto, Y.3    Ichikawa, A.4    Lau, L.F.5    Gibori, G.6
  • 22
    • 0027976193 scopus 로고
    • Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77
    • Liu ZG, Smith SW, McLaughlin KA, Schwartz LM and Osborne BA: Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77. Nature 367: 281-284, 1994.
    • (1994) Nature , vol.367 , pp. 281-284
    • Liu, Z.G.1    Smith, S.W.2    McLaughlin, K.A.3    Schwartz, L.M.4    Osborne, B.A.5
  • 23
    • 0030977267 scopus 로고    scopus 로고
    • Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis
    • Cheng LE, Chan FK, Cado D and Winoto A: Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis. EMBO J 16: 1865-1875, 1997.
    • (1997) EMBO J , vol.16 , pp. 1865-1875
    • Cheng, L.E.1    Chan, F.K.2    Cado, D.3    Winoto, A.4
  • 25
    • 0031734084 scopus 로고    scopus 로고
    • Antisense TR3 orphan receptor can increase prostate cancer cell viability with etoposide treatment
    • Uemura H and Chang C: Antisense TR3 orphan receptor can increase prostate cancer cell viability with etoposide treatment. Endocrinology 139: 2329-2334, 1998.
    • (1998) Endocrinology , vol.139 , pp. 2329-2334
    • Uemura, H.1    Chang, C.2
  • 26
    • 0028008513 scopus 로고
    • Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas
    • Woronicz JD, Calnan B, Ngo V and Winoto A: Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas. Nature 367: 277-281, 1994.
    • (1994) Nature , vol.367 , pp. 277-281
    • Woronicz, J.D.1    Calnan, B.2    Ngo, V.3    Winoto, A.4
  • 27
    • 0036745068 scopus 로고    scopus 로고
    • Orphan nuclear receptors in T lymphocyte development
    • He YW: Orphan nuclear receptors in T lymphocyte development. J Leukoc Biol 72: 440-446, 2002.
    • (2002) J Leukoc Biol , vol.72 , pp. 440-446
    • He, Y.W.1
  • 28
    • 0028807837 scopus 로고
    • A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection
    • Calnan BJ, Szychowski S, Chan FK, Cado D and Winoto A: A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection. Immunity 3: 273-282, 1995.
    • (1995) Immunity , vol.3 , pp. 273-282
    • Calnan, B.J.1    Szychowski, S.2    Chan, F.K.3    Cado, D.4    Winoto, A.5
  • 29
    • 0025729512 scopus 로고
    • Nur77 is differentially modified in PC12 cells upon membrane depolarization and growth factor treatment
    • Hazel TG, Misra R, Davis IJ, Greenberg ME and Lau LF: Nur77 is differentially modified in PC12 cells upon membrane depolarization and growth factor treatment. Mol Cell Biol 11: 3239-3246, 1991.
    • (1991) Mol Cell Biol , vol.11 , pp. 3239-3246
    • Hazel, T.G.1    Misra, R.2    Davis, I.J.3    Greenberg, M.E.4    Lau, L.F.5
  • 31
    • 1342306819 scopus 로고    scopus 로고
    • Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3
    • Lin B, Kolluri SK, Lin F, Liu W, Han YH, Cao X, Dawson MI, Reed JC and Zhang XK: Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3. Cell 116: 527-540, 2004.
    • (2004) Cell , vol.116 , pp. 527-540
    • Lin, B.1    Kolluri, S.K.2    Lin, F.3    Liu, W.4    Han, Y.H.5    Cao, X.6    Dawson, M.I.7    Reed, J.C.8    Zhang, X.K.9
  • 32
    • 11144221595 scopus 로고    scopus 로고
    • Novel function of orphan nuclear receptor Nur77 in stabilizing hypoxia-inducible factor-1alpha
    • Yoo Yg, Yeo MG, Kim DK, Park H and Lee MO: Novel function of orphan nuclear receptor Nur77 in stabilizing hypoxia-inducible factor-1alpha. J Biol Chem 279: 53365-53373, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 53365-53373
    • Yoo, Y.1    Yeo, M.G.2    Kim, D.K.3    Park, H.4    Lee, M.O.5
  • 33
    • 0037226593 scopus 로고    scopus 로고
    • A molecular signature of metastasis in primary solid tumors
    • Ramaswamy S, Ross KN, Lander ES and Golub TR: A molecular signature of metastasis in primary solid tumors. Nat Genet 33: 49-54, 2003.
    • (2003) Nat Genet , vol.33 , pp. 49-54
    • Ramaswamy, S.1    Ross, K.N.2    Lander, E.S.3    Golub, T.R.4
  • 35
    • 0031018683 scopus 로고    scopus 로고
    • Differential expression of NGFI-B and RNR-1 genes in various tissues and developing brain of the rat: Comparative study by quantitative reverse transcription-polymerase chain reaction
    • Bandoh S, Tsukada T, Maruyama K, Ohkura N and Yamaguchi K: Differential expression of NGFI-B and RNR-1 genes in various tissues and developing brain of the rat: comparative study by quantitative reverse transcription-polymerase chain reaction. J Neuroendocrinol 9: 3-8, 1997.
    • (1997) J Neuroendocrinol , vol.9 , pp. 3-8
    • Bandoh, S.1    Tsukada, T.2    Maruyama, K.3    Ohkura, N.4    Yamaguchi, K.5
  • 36
    • 0038243537 scopus 로고    scopus 로고
    • Identification of distinct gene expression profiles associated with treatment of LbetaT2 cells with gonadotropin-releasing hormone agonist using microarray analysis
    • Kakar SS, Winters SJ, Zacharias W, Miller DM and Flynn S: Identification of distinct gene expression profiles associated with treatment of LbetaT2 cells with gonadotropin-releasing hormone agonist using microarray analysis. Gene 308: 67-77, 2003.
    • (2003) Gene , vol.308 , pp. 67-77
    • Kakar, S.S.1    Winters, S.J.2    Zacharias, W.3    Miller, D.M.4    Flynn, S.5
  • 37
    • 0025027340 scopus 로고
    • A human early response gene homologous to murine nur77 and rat NGFI-B, and related to the nuclear receptor superfamily
    • Nakai A, Kartha S, Sakurai A, Toback FG and DeGroot LJ: A human early response gene homologous to murine nur77 and rat NGFI-B, and related to the nuclear receptor superfamily. Mol Endocrinol 4: 1438-1443, 1990.
    • (1990) Mol Endocrinol , vol.4 , pp. 1438-1443
    • Nakai, A.1    Kartha, S.2    Sakurai, A.3    Toback, F.G.4    DeGroot, L.J.5
  • 38
    • 0024443149 scopus 로고
    • Structure, mapping and expression of a growth factor inducible gene encoding a putative nuclear hormonal binding receptor
    • Ryseck RP, Macdonald-Bravo H, Mattei MG, Ruppert S and Bravo R: Structure, mapping and expression of a growth factor inducible gene encoding a putative nuclear hormonal binding receptor. EMBO J 8: 3327-3335, 1989.
    • (1989) EMBO J , vol.8 , pp. 3327-3335
    • Ryseck, R.P.1    Macdonald-Bravo, H.2    Mattei, M.G.3    Ruppert, S.4    Bravo, R.5
  • 39
    • 0001169908 scopus 로고
    • Gonadotropin secretion and its control
    • Knobil E, Neill JD eds, Raven, New York, pp
    • Fink G: Gonadotropin secretion and its control. In: The Physiology of Reproduction. Knobil E, Neill JD (eds). Raven, New York, pp1349-1377, 1988.
    • (1988) The Physiology of Reproduction , pp. 1349-1377
    • Fink, G.1
  • 40
    • 0033735761 scopus 로고    scopus 로고
    • Influence on antiproliferative activity of structural modification and conjugation of gonadotropin-releasing hormone (GnRH) analogues
    • Kalnay A, Palyi I, Vincze B, Mihalik R, Mezo I, Pato J, Seprodi J, Lovas S and Murphy RF: Influence on antiproliferative activity of structural modification and conjugation of gonadotropin-releasing hormone (GnRH) analogues. Cell Prolif 33: 275-285, 2000.
    • (2000) Cell Prolif , vol.33 , pp. 275-285
    • Kalnay, A.1    Palyi, I.2    Vincze, B.3    Mihalik, R.4    Mezo, I.5    Pato, J.6    Seprodi, J.7    Lovas, S.8    Murphy, R.F.9
  • 41
    • 4143145476 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone induces apoptosis of prostate cancer cells: Role of c-Jun NH2-terminal kinase, protein kinase B, and extracellular signal-regulated kinase pathways
    • Kraus S, Levy G, Hanoch T, Naor Z and Seger R: Gonadotropin-releasing hormone induces apoptosis of prostate cancer cells: role of c-Jun NH2-terminal kinase, protein kinase B, and extracellular signal-regulated kinase pathways. Cancer Res 64: 5736-5744, 2004.
    • (2004) Cancer Res , vol.64 , pp. 5736-5744
    • Kraus, S.1    Levy, G.2    Hanoch, T.3    Naor, Z.4    Seger, R.5
  • 42
    • 0345826089 scopus 로고    scopus 로고
    • Cytoskeletal reorganization dependence of signaling by the gonadotropin-releasing hormone receptor
    • Davidson L, Pawson AJ, Millar RP and Maudsley S: Cytoskeletal reorganization dependence of signaling by the gonadotropin-releasing hormone receptor. J Biol Chem 279: 1980-1993, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 1980-1993
    • Davidson, L.1    Pawson, A.J.2    Millar, R.P.3    Maudsley, S.4
  • 43
    • 4143134065 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone receptors: Structure, expression, and signaling transduction
    • Kakar SS, Malik MT, Winters SJ and Mazhawidza W: Gonadotropin-releasing hormone receptors: structure, expression, and signaling transduction. Vitam Horm 69: 151-207, 2004.
    • (2004) Vitam Horm , vol.69 , pp. 151-207
    • Kakar, S.S.1    Malik, M.T.2    Winters, S.J.3    Mazhawidza, W.4
  • 44
    • 34249011126 scopus 로고    scopus 로고
    • Transcriptional regulation of follistatin by GnRH in mouse gonadotroph cell lines: Evidence for a role for cAMP signaling
    • Winters SJ, Ghooray D, Fuji Y, Moore JP Jr, Nevitt JR and Kakar SS: Transcriptional regulation of follistatin by GnRH in mouse gonadotroph cell lines: evidence for a role for cAMP signaling. Mol Cell Endocrinol 271: 45-54, 2007.
    • (2007) Mol Cell Endocrinol , vol.271 , pp. 45-54
    • Winters, S.J.1    Ghooray, D.2    Fuji, Y.3    Moore Jr, J.P.4    Nevitt, J.R.5    Kakar, S.S.6
  • 45
    • 13644269946 scopus 로고    scopus 로고
    • PTTG/securin activates expression of p53 and modulates its function
    • Hamid T and Kakar SS: PTTG/securin activates expression of p53 and modulates its function. Mol Cancer 8: 18, 2004.
    • (2004) Mol Cancer , vol.8 , pp. 18
    • Hamid, T.1    Kakar, S.S.2
  • 46
    • 12344267607 scopus 로고    scopus 로고
    • Reduction of the incidence and severity of collagen-induced arthritis by constitutive Nur77 expression in the T cell lineage
    • De Silva S, Han S, Zhang X, Huston DP, Winoto A and Zheng B: Reduction of the incidence and severity of collagen-induced arthritis by constitutive Nur77 expression in the T cell lineage. Arthritis Rheum 52: 333-338, 2005.
    • (2005) Arthritis Rheum , vol.52 , pp. 333-338
    • De Silva, S.1    Han, S.2    Zhang, X.3    Huston, D.P.4    Winoto, A.5    Zheng, B.6
  • 47
    • 16844384829 scopus 로고    scopus 로고
    • Nur77 regulates lipolysis in skeletal muscle cells: Evidence for crosstalk between the beta-adrenergic and an orphan nuclear hormone receptor pathway
    • Maxwell MA, Cleasby ME, Harding A, Stark A, Cooney GJ and Muscat GE: Nur77 regulates lipolysis in skeletal muscle cells: evidence for crosstalk between the beta-adrenergic and an orphan nuclear hormone receptor pathway. J Biol Chem 280: 12573-12584, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 12573-12584
    • Maxwell, M.A.1    Cleasby, M.E.2    Harding, A.3    Stark, A.4    Cooney, G.J.5    Muscat, G.E.6
  • 49
    • 0030093827 scopus 로고    scopus 로고
    • Comparative distribution of NURR1 and NUR77 nuclear receptors in the mouse central nervous system
    • Saucedo-Cardenas O and Conneely OM: Comparative distribution of NURR1 and NUR77 nuclear receptors in the mouse central nervous system. J Mol Neurosci 7: 51-63, 1996.
    • (1996) J Mol Neurosci , vol.7 , pp. 51-63
    • Saucedo-Cardenas, O.1    Conneely, O.M.2
  • 50
    • 0029857001 scopus 로고    scopus 로고
    • Retinoid X receptor heterodimerization and developmental expression distinguish the orphan nuclear receptors NGFI-B, Nurr1, and Nor1
    • Zetterstrom RH, Solomin L, Mitsiadis T, Olson L and Perlmann T: Retinoid X receptor heterodimerization and developmental expression distinguish the orphan nuclear receptors NGFI-B, Nurr1, and Nor1. Mol Endocrinol 10: 1656-1666, 1996.
    • (1996) Mol Endocrinol , vol.10 , pp. 1656-1666
    • Zetterstrom, R.H.1    Solomin, L.2    Mitsiadis, T.3    Olson, L.4    Perlmann, T.5
  • 51
    • 0034992344 scopus 로고    scopus 로고
    • Gonadotropin regulation of NGFI-B messenger ribonucleic acid expression during ovarian follicle development in the rat
    • Park JI, Park HJ, Choi HS, Lee K, Lee WK and Chun SY: Gonadotropin regulation of NGFI-B messenger ribonucleic acid expression during ovarian follicle development in the rat. Endocrinology 142: 3051-3059, 2001.
    • (2001) Endocrinology , vol.142 , pp. 3051-3059
    • Park, J.I.1    Park, H.J.2    Choi, H.S.3    Lee, K.4    Lee, W.K.5    Chun, S.Y.6
  • 53
    • 0032949438 scopus 로고    scopus 로고
    • Prolonged expression of zinc finger immediate-early gene mRNAs and decreased protein synthesis following kainic acid induced seizures
    • Honkaniemi J and Sharp FR: Prolonged expression of zinc finger immediate-early gene mRNAs and decreased protein synthesis following kainic acid induced seizures. Eur J Neurosci 11: 10-17, 1999.
    • (1999) Eur J Neurosci , vol.11 , pp. 10-17
    • Honkaniemi, J.1    Sharp, F.R.2
  • 54
    • 0031023921 scopus 로고    scopus 로고
    • Neuroendocrine regulation of the hypothalamic pituitary adrenal axis by the nurr1/nur77 subfamily of nuclear receptors
    • Murphy EP and Conneely OM: Neuroendocrine regulation of the hypothalamic pituitary adrenal axis by the nurr1/nur77 subfamily of nuclear receptors. Mol Endocrinol 11: 39-47, 1997.
    • (1997) Mol Endocrinol , vol.11 , pp. 39-47
    • Murphy, E.P.1    Conneely, O.M.2
  • 55
    • 0028265473 scopus 로고
    • Endocrine and neurogenic regulation of the orphan nuclear receptors Nur77 and Nurr-1 in the adrenal glands
    • Davis IJ and Lau LF: Endocrine and neurogenic regulation of the orphan nuclear receptors Nur77 and Nurr-1 in the adrenal glands. Mol Cell Biol 14: 3469-3483, 1994.
    • (1994) Mol Cell Biol , vol.14 , pp. 3469-3483
    • Davis, I.J.1    Lau, L.F.2
  • 56
    • 4444258175 scopus 로고    scopus 로고
    • The orphan nuclear receptor NGFIB regulates transcription of 3beta-hydroxysteroid dehydrogenase. Implications for the control of adrenal functional zonation
    • Bassett MH, Suzuki T, Sasano H, De Vries CJ, Jimenez PT, Carr BR and Rainey WE: The orphan nuclear receptor NGFIB regulates transcription of 3beta-hydroxysteroid dehydrogenase. Implications for the control of adrenal functional zonation. J Biol Chem 279: 37622-37630, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 37622-37630
    • Bassett, M.H.1    Suzuki, T.2    Sasano, H.3    De Vries, C.J.4    Jimenez, P.T.5    Carr, B.R.6    Rainey, W.E.7
  • 58
    • 9644265254 scopus 로고    scopus 로고
    • Synergistic signaling by corticotropin-releasing hormone and leukemia inhibitory factor bridged by phosphorylated 3′,5′-cyclic adenosine monophosphate response element binding protein at the Nur response element (NurRE)-signal transducers and activators of transcription (STAT) element of the proopio-melanocortin promoter
    • Mynard V, Latchoumanin O, Guignat L, Devin-Leclerc J, Bertagna X, Barre BF, Agart J, Coqueret O and Catelli MG: Synergistic signaling by corticotropin-releasing hormone and leukemia inhibitory factor bridged by phosphorylated 3′,5′-cyclic adenosine monophosphate response element binding protein at the Nur response element (NurRE)-signal transducers and activators of transcription (STAT) element of the proopio-melanocortin promoter. Mol Endocrinol 18: 2997-3010, 2004.
    • (2004) Mol Endocrinol , vol.18 , pp. 2997-3010
    • Mynard, V.1    Latchoumanin, O.2    Guignat, L.3    Devin-Leclerc, J.4    Bertagna, X.5    Barre, B.F.6    Agart, J.7    Coqueret, O.8    Catelli, M.G.9
  • 59
    • 0038070656 scopus 로고    scopus 로고
    • Expression of the mouse gonadotropin-releasing hormone receptor gene in alpha T3-1 gonadotrope cells is stimulated by cyclic 3′,5′-adenosine monophosphate and protein kinase A, and is modulated by Steroidogenic factor-1 and Nur77
    • Sadie H, Styger G and Hapgood J: Expression of the mouse gonadotropin-releasing hormone receptor gene in alpha T3-1 gonadotrope cells is stimulated by cyclic 3′,5′-adenosine monophosphate and protein kinase A, and is modulated by Steroidogenic factor-1 and Nur77. Endocrinology 144: 1958-1971, 2003.
    • (2003) Endocrinology , vol.144 , pp. 1958-1971
    • Sadie, H.1    Styger, G.2    Hapgood, J.3
  • 60
    • 0028092770 scopus 로고
    • Gonadotropin-releasing hormone receptors: Structure and signal transduction pathways
    • Stojilkovic SS, Reinhart J and Catt KJ: Gonadotropin-releasing hormone receptors: structure and signal transduction pathways. Endocr Rev 15: 462-499, 1994.
    • (1994) Endocr Rev , vol.15 , pp. 462-499
    • Stojilkovic, S.S.1    Reinhart, J.2    Catt, K.J.3
  • 62
    • 0032893316 scopus 로고    scopus 로고
    • The protein kinase C system acts through the early growth response protein 1 to increase LHbeta gene expression in synergy with steroidogenic factor-1
    • Halvorson LM, Kaiser UB and Chin WW: The protein kinase C system acts through the early growth response protein 1 to increase LHbeta gene expression in synergy with steroidogenic factor-1. Mol Endocrinol 13: 106-116, 1999.
    • (1999) Mol Endocrinol , vol.13 , pp. 106-116
    • Halvorson, L.M.1    Kaiser, U.B.2    Chin, W.W.3
  • 64
    • 0029833617 scopus 로고    scopus 로고
    • Induction of nerve growth factor-induced gene-B (NGFI-B) as an early event in the cyclic adenosine monophosphate response of dog thyrocytes in primary culture
    • Pichon B, Jimenez-Cervantes C, Pirson I, Maenhaut C and Christophe D: Induction of nerve growth factor-induced gene-B (NGFI-B) as an early event in the cyclic adenosine monophosphate response of dog thyrocytes in primary culture. Endocrinology 137: 4691-4698, 1996.
    • (1996) Endocrinology , vol.137 , pp. 4691-4698
    • Pichon, B.1    Jimenez-Cervantes, C.2    Pirson, I.3    Maenhaut, C.4    Christophe, D.5
  • 65
    • 0028954928 scopus 로고
    • Differential regulation of primary response gene expression in skeletal muscle cells through multiple signal transduction pathways
    • Lim RW, Zhu CY and Stringer B: Differential regulation of primary response gene expression in skeletal muscle cells through multiple signal transduction pathways. Biochim Biophys Acta 1266: 91-100, 1995.
    • (1995) Biochim Biophys Acta , vol.1266 , pp. 91-100
    • Lim, R.W.1    Zhu, C.Y.2    Stringer, B.3
  • 66
    • 0026145766 scopus 로고
    • Phorbol ester, forskolin, and serum induction of a human colon nuclear hormone receptor gene related to the NUR 77/NGFI-B genes
    • Bondy GP: Phorbol ester, forskolin, and serum induction of a human colon nuclear hormone receptor gene related to the NUR 77/NGFI-B genes. Cell Growth Differ 2: 203-208, 1991.
    • (1991) Cell Growth Differ , vol.2 , pp. 203-208
    • Bondy, G.P.1
  • 67
    • 0028114709 scopus 로고
    • Induction of NGFI-B gene expression during T cell activation. Role of protein phosphatases
    • Garcia I, Pipaon C, Alemany S and Perez-Castillo A: Induction of NGFI-B gene expression during T cell activation. Role of protein phosphatases. J Immunol 153: 3417-3425, 1994.
    • (1994) J Immunol , vol.153 , pp. 3417-3425
    • Garcia, I.1    Pipaon, C.2    Alemany, S.3    Perez-Castillo, A.4
  • 70
    • 0023161311 scopus 로고
    • Pulsatile release of gonadotropin-releasing hormone (GnRH) from the rat hypothalamus in vitro: Calcium and glucose dependency and inhibition by superactive GnRH analogs
    • Bourguignon JP, Gerard A, Debougnoux G, Rose J and Franchimont P: Pulsatile release of gonadotropin-releasing hormone (GnRH) from the rat hypothalamus in vitro: calcium and glucose dependency and inhibition by superactive GnRH analogs. Endocrinology 121: 993-999, 1987.
    • (1987) Endocrinology , vol.121 , pp. 993-999
    • Bourguignon, J.P.1    Gerard, A.2    Debougnoux, G.3    Rose, J.4    Franchimont, P.5
  • 72
    • 0032230357 scopus 로고    scopus 로고
    • Differential gonadotropin-releasing hormone stimulation of rat luteinizing hormone subunit gene transcription by calcium influx and mitogen-activated protein kinase-signaling pathways
    • Weck J, Fallest PC, Pitt LK and Shupnik MA: Differential gonadotropin-releasing hormone stimulation of rat luteinizing hormone subunit gene transcription by calcium influx and mitogen-activated protein kinase-signaling pathways. Mol Endocrinol 12: 451-457, 1998.
    • (1998) Mol Endocrinol , vol.12 , pp. 451-457
    • Weck, J.1    Fallest, P.C.2    Pitt, L.K.3    Shupnik, M.A.4
  • 73
    • 0036224365 scopus 로고    scopus 로고
    • Transcriptional activation of the ovine follicle-stimulating hormone-beta gene by gonadotropin-releasing hormone involves multiple signal transduction pathways
    • Vasilyev VV, Pernasetti F, Rosenberg SB, Barsoum MJ, Austin DA, Webster NJ and Mellon PL: Transcriptional activation of the ovine follicle-stimulating hormone-beta gene by gonadotropin-releasing hormone involves multiple signal transduction pathways. Endocrinology 143: 1651-1659, 2002.
    • (2002) Endocrinology , vol.143 , pp. 1651-1659
    • Vasilyev, V.V.1    Pernasetti, F.2    Rosenberg, S.B.3    Barsoum, M.J.4    Austin, D.A.5    Webster, N.J.6    Mellon, P.L.7
  • 74
    • 0035895872 scopus 로고    scopus 로고
    • Role of dynamin, Src, and Ras in the protein kinase C-mediated activation of ERK by gonadotropin-releasing hormone
    • Benard O, Naor Z and Seger R: Role of dynamin, Src, and Ras in the protein kinase C-mediated activation of ERK by gonadotropin-releasing hormone. J Biol Chem 276: 4554-4563, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 4554-4563
    • Benard, O.1    Naor, Z.2    Seger, R.3
  • 75
    • 2042441750 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase, Jun N-terminal kinase, p38, and c-Src are involved in gonadotropin-releasing hormone-stimulated activity of the glycoprotein hormone follicle-stimulating hormone beta-subunit promoter
    • Bonfil D, Chuderland D, Kraus S, Shahbazian D, Friedberg I, Seger R and Naor Z: Extracellular signal-regulated kinase, Jun N-terminal kinase, p38, and c-Src are involved in gonadotropin-releasing hormone-stimulated activity of the glycoprotein hormone follicle-stimulating hormone beta-subunit promoter. Endocrinology 145: 2228-2244, 2004.
    • (2004) Endocrinology , vol.145 , pp. 2228-2244
    • Bonfil, D.1    Chuderland, D.2    Kraus, S.3    Shahbazian, D.4    Friedberg, I.5    Seger, R.6    Naor, Z.7
  • 76
    • 0035861586 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone receptor-coupled gene network organization
    • Wurmbach E, Yuen T, Ebersole BJ and Sealfon SC: Gonadotropin-releasing hormone receptor-coupled gene network organization. J Biol Chem 276: 47195-47201, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 47195-47201
    • Wurmbach, E.1    Yuen, T.2    Ebersole, B.J.3    Sealfon, S.C.4
  • 79
    • 0028837044 scopus 로고
    • Gonadotropin-releasing hormone receptor messenger ribonucleic acid expression in rat ovary
    • Whitelaw PF, Eidne KA, Sellar R, Smyth CD and Hillier SG: Gonadotropin-releasing hormone receptor messenger ribonucleic acid expression in rat ovary. Endocrinology 136: 172-179, 1995.
    • (1995) Endocrinology , vol.136 , pp. 172-179
    • Whitelaw, P.F.1    Eidne, K.A.2    Sellar, R.3    Smyth, C.D.4    Hillier, S.G.5
  • 81
    • 0028148727 scopus 로고
    • Expression and regulation of gonadotropin-releasing hormone (GnRH) and GnRH receptor messenger ribonucleic acids in human granulosa-luteal cells
    • Peng C, Fan NC, Ligier M, Vaananen J and Leung PC: Expression and regulation of gonadotropin-releasing hormone (GnRH) and GnRH receptor messenger ribonucleic acids in human granulosa-luteal cells. Endocrinology 135: 1740-1746, 1994.
    • (1994) Endocrinology , vol.135 , pp. 1740-1746
    • Peng, C.1    Fan, N.C.2    Ligier, M.3    Vaananen, J.4    Leung, P.C.5
  • 82
    • 0028795939 scopus 로고
    • Gonadotropin-releasing hormone receptor gene expression in human ovary and granulosa-lutein cells
    • Minaretzis D, Jakubowski M, Mortola JF and Pavlou SN: Gonadotropin-releasing hormone receptor gene expression in human ovary and granulosa-lutein cells. J Clin Endocrinol Metab 80: 430-434, 1995.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 430-434
    • Minaretzis, D.1    Jakubowski, M.2    Mortola, J.F.3    Pavlou, S.N.4
  • 83
    • 0347320615 scopus 로고    scopus 로고
    • The biology of gonadotropin hormone-releasing hormone: Role in the control of tumor growth and progression in humans
    • Limonta P, Moretti RM, Marelli MM and Motta M: The biology of gonadotropin hormone-releasing hormone: role in the control of tumor growth and progression in humans. Front Neuroendocrinol 24: 279-295, 2003.
    • (2003) Front Neuroendocrinol , vol.24 , pp. 279-295
    • Limonta, P.1    Moretti, R.M.2    Marelli, M.M.3    Motta, M.4
  • 84
    • 0037937565 scopus 로고    scopus 로고
    • Potential role of gonadotrophin-releasing hormone (GnRH)-I and GnRH-II in the ovary and ovarian cancer
    • Kang SK, Choi KC, Yang HS and Leung PC: Potential role of gonadotrophin-releasing hormone (GnRH)-I and GnRH-II in the ovary and ovarian cancer. Endocr Relat Cancer 10: 169-177, 2003.
    • (2003) Endocr Relat Cancer , vol.10 , pp. 169-177
    • Kang, S.K.1    Choi, K.C.2    Yang, H.S.3    Leung, P.C.4
  • 86
    • 0027968591 scopus 로고
    • Expression of luteinizing hormone releasing hormone and its mRNA in human endometrial cancer cell lines
    • Irmer G, Burger C, Ortmann O, Schulz KD and Emons G: Expression of luteinizing hormone releasing hormone and its mRNA in human endometrial cancer cell lines. J Clin Endocrinol Metab 79: 916-919, 1994.
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 916-919
    • Irmer, G.1    Burger, C.2    Ortmann, O.3    Schulz, K.D.4    Emons, G.5
  • 87
    • 0028799871 scopus 로고
    • Expression of gonadotropin-releasing hormone and gonadotropin-releasing hormone receptor mRNAs in various non-reproductive human tissues
    • Kakar SS and Jennes L: Expression of gonadotropin-releasing hormone and gonadotropin-releasing hormone receptor mRNAs in various non-reproductive human tissues. Cancer Lett 98: 57-62, 1995.
    • (1995) Cancer Lett , vol.98 , pp. 57-62
    • Kakar, S.S.1    Jennes, L.2
  • 89
    • 34447290678 scopus 로고    scopus 로고
    • LH-RH receptors in human colorectal cancers: Unexpected molecular targets for experimental therapy
    • Szepeshazi K, Schally AV and Halmos G: LH-RH receptors in human colorectal cancers: unexpected molecular targets for experimental therapy. Int J Oncol 30: 1485-1492, 2007.
    • (2007) Int J Oncol , vol.30 , pp. 1485-1492
    • Szepeshazi, K.1    Schally, A.V.2    Halmos, G.3
  • 90
    • 34848921789 scopus 로고    scopus 로고
    • Receptor for luteinizing hormone releasing hormone expressed on melanoma, renal cell carcinoma and non Hodgkin lymphoma can be used for targeted chemotherapy with cytotoxic luteinizing hormone analogues
    • Gaiser T, Ruschoff J, Schally AV, Keller G and Engel JB: Receptor for luteinizing hormone releasing hormone expressed on melanoma, renal cell carcinoma and non Hodgkin lymphoma can be used for targeted chemotherapy with cytotoxic luteinizing hormone analogues. Verh dtsch Ges Pathol 90: 186-192, 2006.
    • (2006) Verh dtsch Ges Pathol , vol.90 , pp. 186-192
    • Gaiser, T.1    Ruschoff, J.2    Schally, A.V.3    Keller, G.4    Engel, J.B.5
  • 91
    • 0036204393 scopus 로고    scopus 로고
    • Down-regulation of proliferation and up-regulation of apoptosis by gonadotropin-releasing hormone agonist in cultured uterine leiomyoma cells
    • Wang Y, Matsuo H, Kurachi O and Maruo T: Down-regulation of proliferation and up-regulation of apoptosis by gonadotropin-releasing hormone agonist in cultured uterine leiomyoma cells. Eur J Endocrinol 146: 447-456, 2002.
    • (2002) Eur J Endocrinol , vol.146 , pp. 447-456
    • Wang, Y.1    Matsuo, H.2    Kurachi, O.3    Maruo, T.4
  • 92
    • 4344637399 scopus 로고    scopus 로고
    • Role of gonadotropin-releasing hormone (GnRH) in ovarian cancer
    • Grundker C and Emons G: Role of gonadotropin-releasing hormone (GnRH) in ovarian cancer. Reprod Biol Endocrinol 1: 65, 2003.
    • (2003) Reprod Biol Endocrinol , vol.1 , pp. 65
    • Grundker, C.1    Emons, G.2
  • 94
    • 39049181907 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone agonists reduce the migratory and the invasive behavior of androgen-independent prostate cancer cells by interfering with the activity of IGF-1
    • Montagnani Marelli M, Moretti RM, Mai S, Procacci P and Limonta P: Gonadotropin-releasing hormone agonists reduce the migratory and the invasive behavior of androgen-independent prostate cancer cells by interfering with the activity of IGF-1. Int J Oncol 30: 261-271, 2007.
    • (2007) Int J Oncol , vol.30 , pp. 261-271
    • Montagnani Marelli, M.1    Moretti, R.M.2    Mai, S.3    Procacci, P.4    Limonta, P.5


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