Neuroendocrine regulation of the hypothalamic pituitary adrenal axis by the nurr1/nur77 subfamily of nuclear receptors

Molecular Endocrinology

Volumn 11, Issue 1, 1997, Pages 39-47

  Murphy, Evelyn P ^a   Conneely, Orla M ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; CORTICOTROPIN RELEASING FACTOR; CYCLIC AMP; FORSKOLIN; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; RECEPTOR SUBTYPE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; BINDING SITE; DNA BINDING; HYPOPHYSIS CELL; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; NEUROENDOCRINE SYSTEM; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY MECHANISM; TRANSACTIVATION;

ANIMALIA;

EID: 0031023921     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.11.1.9874     Document Type: Article

References (52)

1. Evans RM 1988 The steroid and thyroid hormone receptor superfamily. Science 240:889-895
2. Beato M 1989 Gene regulation by steroid hormones. Cell 56:335-344
3. Baniahmad A, Burris TP, Tsai M-J 1994 The nuclear hormone receptor superfamily. In: Tsai M-J, O'Malley BW (eds) MBIU: Mechanism of Steroid Hormone Regulation of Gene Transcription. R. G. Landes Co, Austin, TX, pp 1-24
4. O'Malley BW, Conneely OM 1992 Minireview: Orphan Receptors: in search of a unifying hypothesis for activation. Mol Endocrinol 6:1359-1361
5. Scearce LM, Laz TM, Hazel TG, Lau LF, Taub R 1993 RNR-1, a nuclear receptor in the NGFI-B/Nur77 family that is rapidly induced in degenerating liver. J Biol Chem 268:8855-8861
6. Mages HW, Rilke O, Bravo R, Senger G, Kroczek RA 1994 NOT, a human immediate-early response gene closely related to the steroid/thyroid hormone receptor NAK1/TR3. Mol Endocrinol 8:1583-1591
7. Law SW, Conneely OM, DeMayo FJ, O'Malley BW 1992 Identification of a new brain specific transcription factor, Nurr1. Mol Endocrinol 6:2129-2135
8. Saucedo-Cardenas O, Conneely OM 1996 Comparative distribution of NURR1 and NUR77 nuclear receptors in the mouse central nervous system. J Mol Neurosci 7:51-63
9. Hazel TG, Nathans D, Lau LF 1988 A gene inducible by serum growth factors encodes a member of the steroid and thyroid hormone receptor superfamily. Proc Natl Acad Sci USA 85:8444-8448
10. Milbrandt J 1988 Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene. Neuron 1:183-188
11. Ryseck RP, MacDonald-Bravo H, Mattel MG, Ruppert S, Bravo R 1989 Structure, mapping and expression of a growth factor inducible gene encoding a putative nuclear hormonal binding receptor. EMBO J 8:3327-3335
12. Nakai A, Kartha S, Sakurai A, Toback FG, DeGroot LJ 1990 A human early response gene homologous to murine nur77 and rat NGFI-B, and related to the nuclear receptor superfamily. Mol Endocrinol 4:1438-1443
13. Maruyama K, Tsukada T, Bandoh S, Sasaki K, Ohkura N, Yamaguchi K 1995 Expression of NOR-1 and its closely related members of the steroid/thyroid hormone receptor superfamily in human neuroblastoma cell lines. Cancer Lett 96:117-122
14. Ohkura N, Hijikuro M, Yamamoto A, Miki K 1994 Molecular cloning of a novel thyroid/steroid receptor superfamily gene from cultured rat neuronal cells. Biochem Biophys Res Commun 205:1959-1965
15. Hedvat CV, Irving SG 1995 The isolation and characterization of MINOR, a novel mitogen-inducible nuclear orphan receptor. Mol Endocrinol 9:1692-1700
16. Labelle Y, Zucman J, Stenman G, Kindblom L-G, Knight J, Turc-Carel C, Dockhorn-Dworniczak B, Mandahl N, Desmaze C, Peter M, Aurias A, Delattre O, Thomas G 1995 Oncogenic conversion of a novel orphan nuclear receptor by chromosome translocation. Hum Mol Genet 4:2219-2226
17. Davis IJ, Hazel TG, Lau LF 1991 Transcriptional activation by NUR77, a growth factor inducible member of the steroid hormone receptor superfamily. Mol Endocrinol 5:854-859
18. Wilson TE, Fahrner TJ, Johnston M, Milbrandt J 1991 Identification of the DNA binding site for NGFI-beta by genetic selection in yeast. Science 252:1296-1300
19. Murphy EP, Dobson ADW, Keller CH, Conneely OM 1995 Differential regulation of transcription by the NURR1/NUR77 subfamily of nuclear transcription factors. Gene Express 5:169-179
20. Perlmann T, Jasson L 1995 A novel pathway for vitamin A signalling mediated by RXR heterodimerization with NGFI-B and NURR1 Genes Dev 9:769-782
21. Williams GT, Lau LF 1993 Activation of the inducible orphan receptor gene nur77 by serum growth factors: dissociation of immediate-early and delayed-early responses. Mol Cell Biol 13:6124-6136
22. Watson MA, Milbrandt J 1989 The NGFI-B gene, a transcriptionally inducible member of the steroid receptor gene superfamily: genomic structure and expression in rat brain after seizure induction. Mol Cell Biol 9:4213-4219
23. Arenander AT, de Vellis J, Herschman HR 1989 Induction of c-fos and Tis genes in cultured rat astrocytes by neurotransmitters. J Neurosci 24:107-114
24. Wilson TE, Mouw AR, Weaver CA, Milbrandt J, Parker KL 1993 The orphan nuclear receptor, NGFI-B regulates expression of the gene encoding steroid-21-hydroxylase. Mol Cell Biol 13:861-868
25. Davis IJ, Lau LF 1994 Endocrine and neurogenic regulation of the orphan nuclear receptors Nur77 and Nurr-1 in the adrenal glands. Mol Cell Biol 14:3469-3483
26. Honkaniemi J, Kononen J, Kainu T, Pyykonen I, Pelto-Huikko H 1994 Induction of multiple immediate early genes in rat hypothalamic paraventricular nucleus after stress. Brain Res 25:234-241
27. Chan RKW, Brown ER, Ericsson A, Kovacs KJ, Sawchenko PE 1993 A comparison of two immediate-early genes, c-fos and NGFI-B, as markers for functional activation in stress-related neuroendocrine circuitry. J Neurosci 13:5126-5138
28. Parkes D, Rives S, Lee S, Rivier C, Vale W 1993 Corticotropin-releasing factor activates c-fos, NGFI-B, and corticotropin-releasing factor gene expression within the paraventricular nucleus of the rat hypothalamus. Mol Endocrinol 7:1357-1367
29. Crawford PA, Sadovsky Y, Woodson K, Lee SL, Milbrandt J 1995 Adrenocortical function and regulation of the steroid 21-hydroxylase gene in NGFI-B-deficient mice. Mol Cell Biol 15:4331-4336
30. Roche PJ, Crawford RJ, Ross TF, Tregear GW, Coghlan JP 1988 Nucleotide sequence of the gene coding for ovine corticotropin-releasing factor and regulation of its mRNA levels by glucocorticoids. Gene 71:421-431
31. Jeannotte L, Trijiro MA, Plante RK, Chamberland M, Drouin J 1987 Tissue-specific activity of the pro-opiomelanocortin gene promoter. Mol Cell Biol 7:4058-4066
32. Mishina M, Kurosaki T, Yamamoto T, Notake M, Manu M, Numa S 1982 DNA sequences required for transcription in vivo of the human corticotropin-b-lipotropin precursor gene. EMBO J 1:1533-1538
33. Notake M, Tobimatsu T, Watanabe Y, Takahasni H, Mishina M, Numa S 1983 Isolation and characterization of the mouse corticotropin-b-lipotropin precursor gene and a related pseudogene. FEBS Lett 156:67-71
34. Luckow B, Schutz G 1987 CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements. Nucleic Acids Res 15:5490
35. Gagner J, Drouin J 1987 Tissue-specific regulation of pituitary proopiomelanocortin gene transcription by corticotropin-releasing hormone, 3′, 5′-cyclic adenosine monophosphate, and glucocorticoids. Mol Endocrinol 1:677-682
36. Eberwine JH, Jonassen JA, Evinger MJQ, Roberts JL 1987 Complex transcriptional regulation by glucocorticoids and corticotropin-releasing hormone of proopiomelanocortin gene expression in rat pituitary cultures. DNA 6:483-492
37. Labrie F, Veilleux R, Lefevre G, Coy DH, Sueiras-Diaz J, Schally AV 1982 Corticotropin-releasing factor stimulates accumulation of adenosine 3′, 5′-monophosphate in rat pituitary corticotrophs. Science 216:1007-1008
38. Aguilera G, Harwood JP, Wilson JX, Morell J, Brown JH, Catt KJ 1983 Mechanisms of action of corticotropin-releasing factor and other regulators of corticotropin release in rat pituitary cells. J Biol Chem 258:8039-8045
39. Drouin J, Trifiro MA, Plante RK, Nemer M, Eriksson P, Wrange O 1989 Glucocorticoid receptor binding to a specific DNA sequence is required for hormone-dependent repression of pro-opiomelanocortin gene transcription. Mol Cell Biol 9:5305-5314
40. Drouin J, Sun YL, Chamberland M, Gauthier Y, de Lean A, Nemer M, Schmidt TJ 1993 Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene. EMBO J 12:145-156
41. Liu B, Hammer GD, Rubinstein M, Mortrud M, Low MJ 1992 Identification of DNA elements cooperatively activating proopiomelanocortin gene expression in the pituitary glands of transgenic mice. Mol Cell Biol 12:3978-3990
42. Sugawara T, Holt JA, Kiriakidov M, Strauss III JF 1996 Steroidogenic Factor 1- dependent promoter activity of human steroidogenic acute regulatory protein (StAR) gene. Biochemistry 35:9052-9059
43. Dong Jin W, Boutillier A-L, Glucksman MJ, Salton SRJ, Loeffler J-P, Roberts JL 1994 Characterization of a corticotropin-releasing hormone-responsive element in the rat proopiomelanocortin gene promoter and molecular cloning of its binding protein. Mol Endocrinol 8:1377-1388
44. Riegel AT, Lu Y, Remenick J, Wolford RG, Berard DS, Hager GL 1991 Proopiomelanocortin gene promoter elements required for constitutive and glucocorticoid-repressed transcription. Mol Endocrinol 5:1973-1982
45. Norman CM, Runswick MJ, Pollock R, Treisman R 1988 Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element. Cell 55:989-1003
46. Wong GG, Witek JS, Temple PA, Wilkens KM, Leary AC, Luxenberg DP, Jones SS, Brown EL, Ray RM, Orr EC, Shoemaker C, Golde DW, Kaufman RJ, Hewick RM, Wang EA, Clark SC 1985 Human GM-CSF: molecular cloning of the complimentary DNA and purification of the natural and recombinant proteins. Science 228:810-815
47. Sanger F, Nicklen S, Coulson AR 1977 DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 74:5463-5467
48. Krainer AR, Maniatis T, Ruskin B, Green MR 1984 Normal and mutant b-globin pre mRNAs are faithfully and efficiently spliced in vitro. Cell 36:993-1005
49. Christiano RJ, Smith CL, Kay MA, Brinkley BR, Woo SLC 1993 Hepatic gene therapy: efficient gene delivery and expression in primary hepatocytes utilizing a conjugated adenovirus-DNA complex. Proc Natl Acad Sci USA 90:11548-11552
50. Chomczynski P, Sacchi N 1987 Single-step method of RNA isolation by acid gaunidinium thiocyanate-phenolchloroform extraction. Anal Biochem 162:156-159
51. Bradford MM 1976 A rapid and sensitive method for quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
52. Brian S, Sheen J 1988 A simple phase-extraction assay for chloramphenical acyltransferase activity. Gene 67:271-277