Enzyme nanorings

ACS Nano

Volumn 2, Issue 12, 2008, Pages 2519-2525

  Chou, Tsui Fen ^a   So, Christopher ^b   White, Brian R ^a   Carlson, Jonathan C T ^a   Sarikaya, Mehmet ^b   Wagner, Carsten R ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Chemical dimerization; Dihydrofolate reductase (DHFR); Histidine triad nucleotide binding proteins (Hints); Human hint1; Nanoring; Phosphoramidase; Self assembly

Indexed keywords

DIHYDROFOLATE REDUCTASE (DHFR); HISTIDINE TRIAD NUCLEOTIDE BINDING PROTEINS (HINTS); HUMAN HINT1; NANORING; PHOSPHORAMIDASE;

AMINES; DIMERIZATION; ENZYMES; NANOSTRUCTURED MATERIALS; NUCLEIC ACIDS; NUCLEOTIDES; PROTEINS; SELF ASSEMBLY;

NANORINGS;

DIHYDROFOLATE REDUCTASE; HINT1 PROTEIN, HUMAN; NANOMATERIAL; NERVE PROTEIN;

ARTICLE; ATOMIC FORCE MICROSCOPY; CHEMICAL STRUCTURE; CHEMISTRY;

MICROSCOPY, ATOMIC FORCE; MODELS, MOLECULAR; NANOSTRUCTURES; NERVE TISSUE PROTEINS; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 58149170440     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn800577h     Document Type: Article

References (16)

1. Service, R. F. Nanotechnology Takes Aim at Cancer. Science 2005, 310, 1132-1134.
2. Sarikaya, M.; Tamerler, C.; Jen, A.; Shulten, K.; Baneyx, F. Molecular Biomimetics: Nanotechnology Through Biology. Nat. Mater. 2003, 2, 577-585.
3. Zhang, S.; Marini, D. M.; Hwang, W.; Santoso, S. Design of Nanostructured Biological Materials through Self-Assembly of Peptides and Proteins. Curr. Opin. Chem. Biol. 2002, 6, 865-871.
4. Seeman, N. C. From Genes to Machines: DNA Nanomechanical Devices. Trends Biochem. Sci. 2005, 30, 119-125.
5. Grueninger, D. T. N.; Ziegler, M. O. P.; Koetter, J. W. A.; Schulze, M. S.; Schulz, G. E. Designed Protein-Protein Association. Science 2008, 319, 206-209.
6. Yeates, T. O.; Padilla, J. E. Designing Supramolecular Protein Assemblies. Curr. Opin. Struct. Biol. 2002, 72, 464-470.
7. Carlson, J. C. T.; Kanter, A.; Thuduppathy, G. R.; Cody, V.; Mclvor, R. S.; Wagner, C. R. Designing Protein Dimerizers: The Importance of Ligand Conformational Equilibria. J. Am. Chem. Soc. 2003, 125, 1501-1507.
8. Chou, T.-F.; Tikh, I. B.; Horta, B. A.; Ghosh, B.; de Alencastro, R. B.; Wagner, C. R. Engineered Monomeric Human Histidine Triad Nucleotide Binding Protein 1 Hydrolyzes Fluorogenic Acyl-Adenylate And Lysyl-tRNA Synthetase-Generated Lysyl-Adenylate. J. Biol. Chem. 2007,282, 15137-15147.
9. Chou, T.-F.; Bleganowski, P.; Shillnski, K.; Cheng, J.; Brenner, C.; Wagner, C. R. 31P NMR and Genetic Analysis Establish hinT as the Only Escherchia coli Purine Nucleoside Phosphoramidase and as Essential for Growth under High Salt Conditions. J. Biol. Chem. 2005, 280, 15356-15361.
10. Chou, T.-F.; Baraniak, J.; Kaczmarek, R.; Zhou, X.; Cheng, J.; Ghosh, B.; Wagner, C. R. Phosphoramldate Pronudeotldes: A Comparison of the Phosphoramldase Substrate Specificity of Human and E. coli Histidine Triad Nucleotide Binding Proteins (Hint1). Mol. Pharm. 2007, 4, 208-217.
11. Chou, T.-F.; Wagner, C. R. Lysyl-tRNA SynthetaseGenerated Lysyl-Adenylate is a Substrate for Histidine Triad Nucleotide Binding Proteins. J. Biol. Chem. 2007,282, 4719-4727.
12. Carlson, J. C. T.; Sidhartha, S. J.; Flenniken, M.; Chou, T.-F.; Siegel, R. A.; Wagner, C. R. Chemically Controlled SelfAssembly of Protein Nanorings J. Am. Chem. Soc. 2006, 128, 7630-7638.
13. Ercolani, G. A Model for Self-Assembly in Solution. J. Phys. Chem. B 2003, 107, 5052-5057.
14. Hegner, M.; Wagner, P.; Semenza, G. Ultralarge Atomically Flat Template-Stripped Au Surfaces for Scanning Probe Microscopy. Surf. Sci. 1993, 291, 39-46.
15. Wyatt, J. P. Light Scattering and the Absolute Characterization of Macromolecules. Anal. Chim. Acta 1993, 272, 1-40.
16. Garcia de la Torre, J.; del Rio, G.; Ortega, A. Improved Calculation of Rotational Diffusion and Intrinsic Viscosity of Bead Models for Macromolecules and Nanoparticles. J. Phys. Chem. B 2007, 111, 955-961.