Combination of pursuit eye movement training with prism adaptation and arm movements in neglect therapy: A pilot study

Neurorehabilitation and Neural Repair

Volumn 23, Issue 1, 2009, Pages 58-66

  Keller, Ingo ^a   Lefin Rank, Gudrun ^a   Lösch, Judith ^b   Kerkhoff, Georg ^c  

^a Neurological Clinic   (Germany)

^b University of Landau   (Germany)

^c SAARLAND UNIVERSITY   (Germany)

Author keywords

Hemispatial neglect; Optokinetic stimulation; Prism adaptation

Indexed keywords

ADULT; AGED; ARM MOVEMENT; ARTICLE; BRAIN DAMAGE; BRAIN REGION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HEMIANOPIA; HUMAN; MALE; OPTOKINETIC STIMULATION; PRISM; SMOOTH PURSUIT EYE MOVEMENT; STROKE; STROKE PATIENT; TASK PERFORMANCE; THERAPY EFFECT; TREATMENT RESPONSE; VISUAL FIELD; VISUAL STIMULATION;

ADAPTATION, PHYSIOLOGICAL; AGED; ARM; BRAIN; EYEGLASSES; FEMALE; FUNCTIONAL LATERALITY; HUMANS; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MIDDLE AGED; MOVEMENT; MUSCLE, SKELETAL; NECK MUSCLES; OCULAR MOTILITY DISORDERS; OCULOMOTOR MUSCLES; PARESIS; PERCEPTUAL DISORDERS; PHYSICAL THERAPY MODALITIES; PSYCHOMOTOR PERFORMANCE; PURSUIT, SMOOTH; SPACE PERCEPTION; TREATMENT OUTCOME;

EID: 58149154695     PISSN: 15459683     EISSN: 15526844     Source Type: Journal    
DOI: 10.1177/1545968308317438     Document Type: Article

References (55)

1. Katz N., Hartman-Maeir A., Ring H., Soroker N. Functional disability and rehabilitation outcome in right hemisphere damaged patients with and without unilateral spatial neglect. Arch Phys Med Rehabil. 1999 ; 80: 379-384.
2. Jehkonen M., Ahonen JP, Dastidar P., et al. Visual neglect as a predictor of functional outcome one year after stroke. Acta Neurol Scand. 2000 ; 101: 195-201.
3. Denes G., Semenza C., Stoppa E., Lis A. Unilateral spatial neglect and recovery from hemiplegia. A follow-up study. Brain. 1982 ; 105: 543-552.
4. Rode G., Tiliket C., Boisson D. Predominance of postural imbalance in left hemiparetic patients. Scand J Rehab Med. 1997 ; 29: 11-16.
5. Diller L., Weinberg J. Hemi-inattention in rehabilitation: the evolution of a rational remediation program. Adv Neurol. 1977 ; 18: 63-82.
6. Pizzamiglio L., Antonucci G., Judica A., Montenero P., Razzano C., Zoccolotti P. Cognitive rehabilitation of the hemineglect disorder in chronic patients with unilateral right brain damage. J Clin Exp Neuropsychol. 1992 ; 14: 901-923.
7. Ladavas E., Paladini R., Cubelli R. Implicit associative priming in a patient with left visual neglect. Neuropsychologia. 1993 ; 31: 1307-1320.
8. Antonucci G., Guariglia C., Judica A., et al. Effectiveness of neglect rehabilitation in a randomized group study. J Clin Exp Neuropsychol. 1995 ; 17: 383-389.
9. Kerkhoff G. Rehabilitation of visuospatial cognition and visual exploration in neglect: a cross-over study. Restor Neurol Neurosci. 1998 ; 12: 27-40.
10. Robertson I. Cognitive rehabilitation: attention and neglect. Trends Cogn Sci. 1999 ; 3: 385-393.
11. Schindler I., Kerkhoff G., Karnath HO, Keller I., Goldenberg G. Neck muscle vibration induces lasting recovery in spatial neglect. J Neurol Neurosurg Psychiatry. 2002 ; 73: 412-419.
12. Vallar G., Lobel E., Galati G., Berthoz A., Pizzamiglio L., Le Bihan D. A fronto-parietal system for computing the egocentric spatial frame of reference in humans. Exp Brain Res. 1999 ; 124: 281-286.
13. Cappa S., Sterzi R., Vallar G., Bisiach E. Remission of hemineglect and anosognosia during vestibular stimulation. Neuropsychologia. 1987 ; 25: 775-782.
14. Vallar G., Sterzi R., Bottini G., Cappa S., Rusconi ML Temporary remission of left hemianesthesia after vestibular stimulation. A sensory neglect phenomenon. Cortex. 1990 ; 26: 123-131.
15. Karnath HO, Christ K., Hartje W. Decrease of contralateral neglect by neck muscle vibration and spatial orientation of trunk midline. Brain. 1993 ; 116: 383-396.
16. Vallar G., Guariglia C., Nico D., Pizzamiglio L. Motor deficits and optokinetic stimulation in patients with left hemineglect. Neurology. 1997 ; 49: 1364-1370.
17. Rossi PW, Kheyfets S., Reding MJ Fresnel prisms improve visual perception in stroke patients with homonymous hemianopia or unilateral visual neglect. Neurology. 1990 ; 40: 1597-1599.
18. Rossetti Y., Rode G., Pisella L., Farné A., Boisson D., Perenin MT Prism adaptation to a rightward optical deviation rehabilitates left hemispatial neglect. Nature. 1998 ; 395: 166-169.
19. Frassinetti F., Angeli V., Meneghello F., Làdavas E. Long-lasting amelioration of visuospatial neglect by prism adaptation. Brain. 2002 ; 125: 608-623.
20. Rode G., Klos T., Courtois-Jacquin S., Rossetti Y., Pisella L. Neglect and prism adaptation: a new therapeutic tool for spatial cognition disorders. Restor Neurol Neurosci. 2006 ; 24: 347-356.
21. Pizzamiglio L., Frasca R., Guariglia C., Incoccia C., Antonucci G. Effect of optokinetic stimulation in patients with visual neglect. Cortex. 1990 ; 26: 535-540.
22. Kerkhoff G. Multiple perceptual distortions and their modulation in patients with left visual neglect. Neuropsychologia. 2000 ; 38: 1073-1086.
23. Mattingley JB, Bradshaw JL, Bradshaw JA Horizontal visual motion modulates focal attention in left unilateral spatial neglect. J Neurol Neurosurg Psychiatry. 1994 ; 57: 1228-1235.
24. Karnath HO Optokinetic stimulation influences the disturbed perception of body orientation in spatial neglect. J Neurol Neurosurg Psychiatry. 1996 ; 60: 217-220.
25. Kerkhoff G., Schindler I., Keller I., Marquardt C. Visual background motion reduces size distortion in spatial neglect. NeuroReport. 1999 ; 10: 319-323.
26. Vallar G., Antonucci G., Guariglia C., Pizzamiglio L. Deficits of position sense, unilateral neglect, and optokinetic stimulation. Neuropsychologia. 1993 ; 31: 1191-1200.
27. Vallar G., Guariglia C., Magnotti, L., Pizzamiglio L. Optokinetic stimulation affects both vertical and horizontal deficits of position sense in unilateral neglect. Cortex. 1995 ; 31: 669-683.
28. Nico D. Effectiveness of sensory stimulation on tactile extinction. Exp Brain Res. 1999 ; 127: 75-82.
29. Pizzamiglio L., Fasotti L., Jehkonen M., et al. The use of optokinetic stimulation in rehabilitation of the hemineglect disorder. Cortex. 2004 ; 40: 441-450.
30. Schindler I., Kerkhoff G. Convergent and divergent effects of neck proprioceptive and visual motion stimulation on visual space processing in neglect. Neuropsychologia. 2004 ; 42: 1149-1155.
31. Kerkhoff G., Keller I., Ritter V., Marquardt C. Repetitive optokinetic stimulation induces lasting recovery from visual neglect. Restor Neurol Neurosci. 2006 ; 24: 357-369.
32. Sturm W., Thimm M., Fink GR Alertness-training in neglect: behavioural and imaging results. Restor Neurol Neurosci. 2006 ; 24: 371-384.
33. Robertson IH, Hogg K., McMillan M. Rehabilitation of unilateral neglect: Improving function by contralesional limb activation. Neuropsychol Rehabil. 1998 ; 8: 19-29.
34. Kerkhoff G. Hemispatial neglect in man. Prog Neurobiol. 2001 ; 63: 1-27.
35. Konczak J., Karnath HO Kinematics of goal-directed arm movements in neglect: control of hand velocity. Brain Cogn. 1998 ; 37: 387-403.
36. Chokron S., Bartolomeo P. Position of the egocentric reference and directional arm movements in right-brain-damaged patients. Brain Cogn. 1998 ; 37: 405-418.
37. Neggers SF, Bekkering H. Ocular gaze is anchored to the target of an ongoing pointing movement. J Neurophysiol. 2000 ; 83: 639-651.
38. Neggers SF, Bekkering H. Coordinated control of eye and hand movements in dynamic reaching. Hum Mov Sci. 2002 ; 21: 349-376.
39. Werner W., Hoffmann KP, Dannenberg S. Anatomical distribution of arm-movement-related neurons in the primate superior colliculus and underlying reticular formation in comparison with visual and saccadic cells. Exp Brain Res. 1997 ; 115: 206-216.
40. Stuphorn V., Bauswein E., Hoffmann KP Neurons in the primate superior colliculus coding for arm movements in gaze-related coordinates. J Neurophysiol. 2000 ; 83: 1283-1299.
41. Rorden C., Brett M. Stereotaxic display of brain lesions. Behav Neurol. 2000 ; 12: 191-200.
42. Keller I., Ditterich J., Eggert T., Straube A. Size distortion in spatial neglect. NeuroReport. 2000 ; 11: 1655-1660.
43. Doricchi F., Siegler I., Iaria G., Berthoz A. Vestibo-ocular and optokinetic impariments in left unilateral neglect. Neuropsychologia. 2002 ; 40: 2084-2099.
44. Waespe W., Henn V. Vestibular nuclei activity during optokinetic after-nystagmus (OKAN) in the alert monkey. Exp Brain Res. 1977 ; 30: 323-330.
45. Schenk T., Zihl J. Visual motion perception after brain damage: I. Deficits in global motion perception. Neuropsychologia. 1997 ; 35: 1289-1297.
46. Brandt T., Bucher SF, Seelos KC, Dieterich M. Bilateral functional MRI activations of the basal ganglia and middle temporal/medial superior temporal motion-sensitive areas-optokinetic stimulation in homonymous hemianopia. Arch Neurol. 1998 ; 55: 1126-1131.
47. Gur S., Ron S. Training in oculomotor tracking: occupational health aspects. Isr J Med Sci. 1992 ; 28: 622-628.
48. Konen CS, Kleiser R., Seitz RJ, Bremmer F. An fMRI study of optokinetic nystagmus and smooth-pursuit eye movements in humans. Exp Brain Res. 2005 ; 165: 203-216.
49. Luaute J., Michel C., Rode G., et al. Functional anatomy of the therapeutic effects of prism adaptation on left neglect. Neurology. 2006 ; 66: 1859-1867.
50. Wolpert DM, Kawato M. Multiple paired forward and inverse models for motor control. Neural Netw. 1998 ; 11: 1317-1329.
51. Robertson I., Manly T. Cognitive routes to the rehabilitation of unilateral neglect. In: Karnath HO, Milner AD, Vallar G. eds. The Cognitive and Neural Bases of Spatial Neglect. Oxford, UK: Oxford University Press; 2002: 365-374.
52. Rode G., Pisella L., Rossetti Y., Farnè A., Boisson D. Bottom-up transfer of sensory-motor plasticity to recovery of spatial cognition: visuomotor adaptation and spatial neglect. In: Prablanc C, Pélisson D, Rossetti Y, eds. Progress in Brain Research. Amsterdam, the Netherlands: Elsevier Science; 2003: 273-287.
53. Fierro B., Brighina F., Bisiach E. Improving neglect by TMS. Behav Neurol. 2006 ; 17: 169-176.
54. Robertson I., North NT One hand is better than two: motor extinction of left hand advantage in unilateral neglect. Neuropsychologia. 1992 ; 30: 553-563.
55. Lux S., Thimm M., Marshall JC, Fink GR Directed and divided attention during hierarchical processing in patients with visuo-spatial neglect and matched healthy volunteers. Neuropsychologia. 2006 ; 44: 436-444.