Measles virus entry inhibitors: a structural proposal for mechanism of action and the development of resistance

Biochemistry

Volumn 47, Issue 51, 2008, Pages 13573-13583

  Prussia, Andrew J ^a   Plemper, Richard K ^b   Snyder, James P ^a  

^a EMORY UNIVERSITY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING STUDIES; CONFORMATIONAL CHANGES; CONFORMATIONAL INTERMEDIATES; DESTABILIZING EFFECTS; DIFFERENTIAL FUSIONS; DO-MAINS; FUSION PROTEINS; MEASLES VIRUSES; MECHANISM OF ACTIONS; STRUCTURAL BASES; STRUCTURAL MODELS; TARGET CELLS;

BIOCHEMISTRY; INTERNET; MACHINERY; SPACECRAFT; VIRUSES;

MODEL STRUCTURES;

ANTIVIRUS AGENT; HYBRID PROTEIN;

ANIMAL CELL; ANTIVIRAL RESISTANCE; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG MECHANISM; GENE MUTATION; HYDROPHOBICITY; MEASLES VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; TEMPERATURE; VIRUS ENTRY;

ANIMALS; ANTIVIRAL AGENTS; CERCOPITHECUS AETHIOPS; COMPUTER SIMULATION; DIMERIZATION; DRUG RESISTANCE, VIRAL; INHIBITORY CONCENTRATION 50; MEASLES VIRUS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; VERO CELLS;

MEASLES VIRUS;

EID: 58149151220     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi801513p     Document Type: Article

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