Functional analysis of avian metallothionein isoforms: An ecotoxicological approach for assessing potential tolerability to element exposure

Environmental Science and Technology

Volumn 42, Issue 24, 2008, Pages 9391-9396

  Nam, Dong Ha ^a   Kim, Eun Young ^a   Iwata, Hisato ^a  

^a EHIME UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AVIAN POPULATIONS; ECOTOXICOLOGICAL; HEPATIC CONCENTRATIONS; HG CONCENTRATIONS; IN VITRO; ISOFORM; ISOFORMS; MASKING EFFECTS; METALLOTHIONEIN; METALLOTHIONEIN ISOFORMS; MULTIPLE ELEMENTS; TRANSACTIVATION;

ARSENIC; CHROMIUM; CHROMIUM COMPOUNDS; COPPER; DETOXIFICATION; ESCHERICHIA COLI; GENES; HEAVY METALS; LEAD; MERCURY (METAL); PROTEINS; RUBIDIUM; SILVER; ZINC;

TELLURIC PROSPECTING;

ARSENIC; BIOACCUMULATION; COLIFORM BACTERIUM; DETOXIFICATION; DOSE-RESPONSE RELATIONSHIP; ECOTOXICOLOGY; GROWTH RATE; HEAVY METAL; METALLOTHIONEIN; METHYLMERCURY; POLLUTION EXPOSURE; POLLUTION TOLERANCE; WATERFOWL; WILD POPULATION;

ANIMALS; BASE SEQUENCE; BIRDS; ECOTOXICOLOGY; ELEMENTS; ENHANCER ELEMENTS, GENETIC; ENVIRONMENTAL EXPOSURE; ESCHERICHIA COLI; LIVER; METALLOTHIONEIN; METALS, HEAVY; PROMOTER REGIONS, GENETIC; PROTEIN ISOFORMS; SPECIES SPECIFICITY; TOXICITY TESTS; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION;

ANAS PLATYRHYNCHOS; AVES; ESCHERICHIA COLI; PHALACROCORACIDAE; PHALACROCORAX CARBO;

EID: 58149148252     PISSN: 0013936X     EISSN: None     Source Type: Journal    
DOI: 10.1021/es801332p     Document Type: Article

References (32)

1. Klaassen, C. D.; Liu, J.; Choudhuri, S. Metallothionein: an intracellular protein to protect against cadmium toxicity. Annu. Rev. Pharmacol. Toxicol. 1999, 39, 267-294.
2. Miles, A. T.; Hawksworth, G. M.; Beattie, J. H.; Rodilla, V. Induction, regulation, degradation, and biological significance of mammalian metallothioneins. Crit. Rev. Biochem. Mol. Biol. 2000, 35, 35-70.
3. Haq, F.; Mahoney, M.; Koropatnick, J. Signaling events for metallothionein induction. Mutat. Res. 2003, 533, 211-226.
4. Andrew, G. K. Cellular zinc sensors: MTF-1 regulation of gene expression. BioMetals 2001, 14, 223-237.
5. Koizumi, S.; Suzuki, K.; Ogra, Y.; Yamada, H.; Otsuka, F. Transcriptional activity and regulatory protein binding of metal-responsive elements of the human metallothionein-IIA gene. Eur. J. Biochem. 1999, 259, 635-642.
6. Fernando, L. P.; Andrews, G. K. Cloning and expression of an avian metallothionein-ending gene. Gene 1989, 81, 177-183.
7. Dalton, T.; Paria, B. C.; Fernando, L. P.; Huet-Hudson, Y. M.; Dey, S. K.; Andrews, G. K. Activation of the chicken metallothionein promoter by metals and oxidative stress in cultured cells and transgenic mice. Comp. Biochem. Physiol., Part B: Biochem. Mol. Biol. 1997, 116, 75-86.
8. Villarreal, L.; Tío, L.; Capdevila, M.; Atrian, S. Comparative metal binding and genomic analysis of the avian (chicken) and mammalian metallothionein. FEBS J. 2006, 273, 523-535.
9. Nam, D.-H.; Kim, E.-Y.; Iwata, H.; Tanabe, S. Molecular characterization of two metallothionein isoforms in avian species: Evolutionary history, tissue distribution profile, and expression associated with metal accumulation. Comp. Biochem. Physiol., Part C: Pharmacol., Toxicol. Endocrinol. 2007, 145, 295-305.
10. Searle, P.; Davison, B. L.; Stuart, G. W.; Wilkie, T. M.; Norstedt, G.; Palmiter, R. Regulation, linkage, and sequence of mouse metallothionein I and II genes. Mol. Cell. Biol. 1984, 4, 1221-1230.
11. Yagle, M. K.; Palmiter, R. Coordinate regulation of mouse metallothionein I and II genes by heavy metals and glucocorticoids. Mol. Cell. Biol. 1985, 5, 291-294.
12. Richards, R. I.; Heguy, A.; Karin, M. Structural and functional analysis of the human metallothionein-IA gene: differential induction by metal ions and glucocorticoids. Cell 1984, 37, 263-272.
13. Palmiter, R. D. Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active transcription factor, MTF-1. Proc. Natl. Acad. Sci. U.S.A. 1994, 91, 1219-1223.
14. Palmiter, R. D. The elusive function of metallothioneins. Proc. Natl. Acad. Sci. U.S.A. 1998, 95, 8428-8430.
15. Stuart, G. W.; Searle, P. F.; Palmiter, R. D. Identification of multiple metal regulatory elements in mouse metallothionein-1 promoter by assaying synthetic sequences. Nature 1985, 317, 828-831.
16. Rocha, J. B. T.; Tuerlinckx, S. M.; Schetinger, M. R. C.; Folmer, V. Effects of group 13 metals on porphobilinogen synthase in viro. Toxicol. Appl. Pharmacol. 2004, 200, 169-176.
17. Kreppel, H.; Bauman, J. W.; Liu, J.; McKim, J. M., Jr.; Klaassen, C. D. Induction of metallothionein by arsenicals in mice. Fundam. Appl. Toxicol. 1993, 20, 184-189.
18. Dufresne, J.; Cyr, D. G. Effects of short-term methyl mercury exposure on metallothionein mRNA levels in the testis and epididymis of the rat. J. Androl. 1999, 20, 769-778.
19. Solis-Heredia, M. J.; Quintanilla-Vega, B.; Sierra-Santoyo, A.; Hernandez, J. M.; Brambila, E.; Cebrian, M. E.; Albores, A. Chromium increases pancreatic metallothionein in the rat. Toxicology 2000, 142, 111-117.
20. Carter, A. D.; Felber, B. K.; Walling, M.; Jubier, M.-F.; Schmidt, C. J.; Hamer, D. H. Duplicated heavy metal control sequences of the mouse metallothionein-I gene. Proc. Natl. Acad. Sci. U.S.A. 1984, 81, 7392-7396.
21. Lehman-McKeeman, L. D.; Kershaw, W. C.; Klaassen, C. D. Species differences in metallothionein regulation: a comparison of the induction of isometallothioneins in rats and mice. In Metallothionein in Biology and Medicine; Klaassen, C. D., Suzuki, K. T., Eds.; CRC Press: Boca Raton, FL, 2000.
22. Arizono, K.; Ito, T.; Ota, S.; Ariyoshi, T. Purification and characterization of lead-induced zinc thionein in the liver of rats. Bull. Environ. Contam. Toxicol. 1985, 35, 143-148.
23. Waalkes, M. P.; Klaassen, C. D. Concentration of metallothionein in major organs of rats after administration of various metals. Fundam. Appl. Toxicol. 1985, 5, 473-477.
24. Ikebuchi, H.; Teshima, R.; Suzuki, K.; Terao, T.; Yamane, Y. Simultaneous induction of Pb-metallothionein-like protein and Zn-thionein in the liver of rats given lead acetate. Biochem. J. 1986, 233, 541-546.
25. Scheuhammer, A. M.; Onosaka, S.; Rodgers, K.; Cherian, M. G. The interaction of zinc and cadmium in the synthesis of hepatic metallothionein in rats. Toxicology 1985, 36, 101-108.
26. Majumder, S.; Ghoshal, K.; Summers, D.; Bai, S.; Datta, J.; Jacob, S. T. Chromium (VI) down-regulates heavy metal-induced metallothionein gene transcription by modifying transactivation potential of the key transcription factor, metal-responsive transcription factor 1. J. Biol. Chem. 2003, 278, 26216-26226.
27. Hou, Y.-H.; Kim, R.; Kim, S.-H. Expression of the mouse metallothionein-1 gene in Escherichia coli: increased tolerance to heavy metals. Biochim. Biophys. Acta 1988, 951, 230-234.
28. Odawara, F.; Kurasaki, M.; Suzuki-Kurasaki, M.; Oikawa, S.; Emoto, T.; Yamasaki, F.; Arias, A. R. L.; Kojima, Y. Expression of human metallothione-2 in Escherichia coli: cadmium tolerance of transformed cells. J. Biochem. 1995, 118, 1131-1137.
29. Zheng, W.-J.; Wu, F.; Zhuang, H.-Q.; Lu, C.; Yang, F.; Ma, W.-L.; Hua, Z.-C. Expression of human metallothionein III and its metalloabsorption capability in Escherichia coli. Prep. Biochem. Biotechnol. 2004, 34, 265-278.
30. Cooksey, D. A. Molecular mechanism of copper resistance and accumulation in bacteria. FEMS Microbiol. Rev. 1994, 14, 381-386.
31. Helmann, J.D. Metal cation regulation in gram-positive bacteria. In Metal ions in gene regulation; Silver, S., Walden, W., Eds.; Chapman & Hall, New York, 1997.
32. Nies, D. H.; Brown, N. L. Two-component system in the regulation of heavy metal resistance. In Metal ions in gene regulation, Silver, S., Walden, W., Eds.; Chapman & Hall: New York, 1997.