Fixed dose combination of cefepime plus amikacin prevent oxidative stress in liver of Mus musculus mice

Current Clinical Pharmacology

Volumn 3, Issue 3, 2008, Pages 211-214

  Chaudhary, Manu ^a   Soni, Arvind ^a   Dwivedi, Vivek Kumar ^a  

^a Venus Medicine Research Centre   (India)

Author keywords

Amikacin; Antioxidant enzymes; Cefepime plus amikacin; Fixed dose combination; Malonaldialdehyde

Indexed keywords

AMIKACIN; ANTIBIOTIC AGENT; CATALASE; CEFEPIME PLUS AMIKACIN; FREE RADICAL; LIPID; MALONALDEHYDE; POTENTOX; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; ANTIOXIDANT; CEFEPIME; CEPHALOSPORIN DERIVATIVE;

ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; LIPID PEROXIDATION; LIVER; LIVER INJURY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REVIEW; ANIMAL; ARTICLE; DRUG COMBINATION; DRUG EFFECT; METABOLISM;

AMIKACIN; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIOXIDANTS; CATALASE; CEPHALOSPORINS; DRUG COMBINATIONS; LIPID PEROXIDATION; LIVER; MALONDIALDEHYDE; MICE; OXIDATIVE STRESS; SUPEROXIDE DISMUTASE;

EID: 58149132334     PISSN: 15748847     EISSN: None     Source Type: Journal    
DOI: 10.2174/157488408785747683     Document Type: Review

References (22)

1. Conlon BJ, Aran JM, Erre JP, et al. Attenuation of aminoglycoside induced cochlear damage with the metabolic antioxidant alphalipoic acid. Hear Res 1999; 128: 40-44.
2. Rybak LP, Whitworth CA. Ototoxicity: therapeutic opportunities. Drug Dis Today 2005; 10 (19): 1313-21.
3. R in Transgenic Mice Causes Resistance to toxic Effects of Hygromycin B In Vivo. J Pharmacol Exp Ther 1997; 281: (2) 992-7.
4. Klemens JJ, Meech RP, Hughes LF, et al. Antioxidant enzyme levels inversely Covary with hearing loss after amikacin treatment. J Am Acad Audiol 2003; 14 (4): 134-42.
5. Martines G, Butturini L, Menozzi I, et al. Amikacin-induced liver toxicity: correlations between biochemical indexes and ultrastructural features in an experimental model. Rev Med Univ Navarra 1988; 32 (1): 41-45.
6. Pedraza CJ, Maldonado PD, Medina CO, et al. Garlic ameliorates gentamicin nephrotoxicity: relation antioxidant enzymes. Free Radic Biol Med 2000; 29: 602-611.
7. Laurent G, Carlier MB, Rollman B, et al. Mechanism of aminoglycoside-induced lysosomal phospholipidosis: In vitro and in vivo studies with gentamycin and amikacin. Biochem Pharmacol 1982; 31: 3861-70.
8. Laurent G, Kishore BK, Tulkens PM. Aminoglycoside-induced renal phospholipidosis and nephrotoxicity. Biochem Pharmacol 1990; 40: 2383-92.
9. Gonzalez A, Jimenez A, Vazquez D, et al. Studies on the mode of action of hygromycin B, an inhibitor of translocation in eukaryotes. Biochem Biophys Acta 1978; 521:459-69.
10. Carreer R, Deby-Dupont G, Deby C, et al. Oxidant-scavenging activities of beta-lactam agents. Eur J Clin Microbiol Infect Dis 1998; 17(1): 43-46.
11. Yazaki T, Yoshiyama Y, Wong P, et al. Protective effect of fleroxacin aganist the nephrotoxicity of isepamicin in rat. Biol Pharm Bull 2002; 25 (4): 516-9.
12. Chaudhary M, Shrivastava SM. Minimum inhibitory concentration of ceftriaxone and vancomycin in methicillin resistant Staphylococcus aureus, Entrococcus faecalis and Streptococcus pneumoniae. J Natcon 2006; 18 (1): 177-81.
13. Misra HP, Fridovich I. The role of superoxide anion in the autooxidation of epinephrine and a sample assay for Super-oxide dismutase. J Biol Chem 1972; 247: 3170-3175.
14. Luck. Catalase. In: Bergmeyer HU, Ed. Method in Enzymatic analysis. NY: Academic Press. 1965; 885-894.
15. Ohkawa H, Ohishi N, Yagi K. Assay of lipid per-oxidation in animal tissue by thio barbutric acid reaction. Anal Biochem 1979; 95: 351-8.
16. Schacht J, Weiner N. Aminoglycoside-induced hearing loss: a molecular hypothesis. ORL J Otorhinolaryngol Relat Spec 1986; 48 (2): 116-23.
17. Montserrat B,Victoria L, Albina ML, et al. Melatonin reduces uranium-induced nephrotoxicity in rats. J Pineal Res 2007; 43 (1): 87-95.
18. Bendush CL, Weber R. Tobramycin sulphate: A summary of worldwide experience form clinical trial. J Infect Dis 1976; 134: 219-30.
19. Lietz T, Bryła J. The effect of various aminoglycoside antibiotics on glycogen phosphorylase activity in liver and kidney medulla of rabbit. Acta Biochim Pol 1990; 37 (1): 187-90.
20. Tumah H. Fourth- generation Cephalosporins: In vitro activity against nosocomial gram-negative bacilli compared with betalactum antibiotics and ciprofloxacin. Chemotherapy 2005; 51(2-3): 80-5.
21. Sukru O, Mustafa E, Ahmet K, et al Effects of hyperbaric oxygen treatment on liver functions, oxidative status and histology in septic rats. Int Care Med 2005; 31 (9): 1262-8.
22. Lapenna D, Cellini L, Gioia DS, et al. Cephalosporins are scavengers of hypochlorous acid. Biochem Pharmacol 1995; 49 (9): 1249-54.