메뉴 건너뛰기




Volumn 16, Issue 1, 2009, Pages 3-8

Advances in diagnosis and treatment of eosinophilia

Author keywords

Chronic eosinophilic leukemia; Eosinophilia; Eosinophils; Hypereosinophilic syndrome; Imatinib

Indexed keywords

ALEMTUZUMAB; ALPHA INTERFERON; CD5 ANTIGEN; CYANOCOBALAMIN; CYCLOSPORIN A; HYDROXYUREA; IMATINIB; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 5; MEPOLIZUMAB; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; T LYMPHOCYTE RECEPTOR; THYMUS AND ACTIVATION REGULATED CHEMOKINE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FIP1L1; TROPONIN; TRYPTASE; UNCLASSIFIED DRUG;

EID: 58149127252     PISSN: 10656251     EISSN: 15317048     Source Type: Journal    
DOI: 10.1097/MOH.0b013e32831c841f     Document Type: Review
Times cited : (26)

References (44)
  • 1
    • 0028323393 scopus 로고
    • The idiopathic hypereosinophilic syndrome
    • Weller PF, Bubley GJ. The idiopathic hypereosinophilic syndrome. Blood 1994; 83:2759-2779.
    • (1994) Blood , vol.83 , pp. 2759-2779
    • Weller, P.F.1    Bubley, G.J.2
  • 2
    • 0033989934 scopus 로고    scopus 로고
    • Hypereosinophilia
    • Bain BJ. Hypereosinophilia. Curr Opin Hematol 2000; 7:21-25.
    • (2000) Curr Opin Hematol , vol.7 , pp. 21-25
    • Bain, B.J.1
  • 3
    • 0038315443 scopus 로고    scopus 로고
    • The hypereosinophilic syndrome revisited
    • Roufosse F, Cogan E, Goldman M. The hypereosinophilic syndrome revisited. Annu Rev Med 2003; 54:169-184.
    • (2003) Annu Rev Med , vol.54 , pp. 169-184
    • Roufosse, F.1    Cogan, E.2    Goldman, M.3
  • 4
    • 33646900800 scopus 로고    scopus 로고
    • The hypereosinophilic syndromes working group. Approaches to the treatment of hypereosinophilic syndromes: A workshop summary report
    • Klion AD, Bochner BS, Gleich GJ, et al. The hypereosinophilic syndromes working group. Approaches to the treatment of hypereosinophilic syndromes: a workshop summary report. J Allergy Clin Immunol 2006; 117:1292-1302.
    • (2006) J Allergy Clin Immunol , vol.117 , pp. 1292-1302
    • Klion, A.D.1    Bochner, B.S.2    Gleich, G.J.3
  • 5
    • 34548509941 scopus 로고    scopus 로고
    • Clinical overview of hypereosinophilic syndromes
    • Sheikh J, Weller PF. Clinical overview of hypereosinophilic syndromes. Immunol Allergy Clin North Am 2007; 27:333-355.
    • (2007) Immunol Allergy Clin North Am , vol.27 , pp. 333-355
    • Sheikh, J.1    Weller, P.F.2
  • 7
    • 0016430025 scopus 로고
    • The hypereosinophilic syndrome: Analysis of fourteen cases with review of the literature
    • Chusid MJ, Dale DC, West BC, Wolff SM. The hypereosinophilic syndrome: analysis of fourteen cases with review of the literature. Medicine (Baltimore) 1975; 54:1-27.
    • (1975) Medicine (Baltimore) , vol.54 , pp. 1-27
    • Chusid, M.J.1    Dale, D.C.2    West, B.C.3    Wolff, S.M.4
  • 8
    • 0014299959 scopus 로고
    • The hypereosinophilic syndromes
    • Hardy WR, Anderson RE. The hypereosinophilic syndromes. Ann Intern Med 1968; 68:1220-1229.
    • (1968) Ann Intern Med , vol.68 , pp. 1220-1229
    • Hardy, W.R.1    Anderson, R.E.2
  • 9
    • 0024345311 scopus 로고
    • Prognostic factors of hypereosinophilic syndrome. Study of 40 cases
    • Lefebvre C, Bletry O, Degoulet P, et al. Prognostic factors of hypereosinophilic syndrome. Study of 40 cases. Ann Med Interne (Paris) 1989; 140:253-257.
    • (1989) Ann Med Interne (Paris) , vol.140 , pp. 253-257
    • Lefebvre, C.1    Bletry, O.2    Degoulet, P.3
  • 10
    • 0021055261 scopus 로고
    • Clinical features of fifteen patients with the hypereosinophilic syndrome
    • Spry CJ, Davies J, Tai PC, et al. Clinical features of fifteen patients with the hypereosinophilic syndrome. Q J Med 1983; 52:1-22.
    • (1983) Q J Med , vol.52 , pp. 1-22
    • Spry, C.J.1    Davies, J.2    Tai, P.C.3
  • 12
    • 11844264836 scopus 로고    scopus 로고
    • Pediatric hypereosinophilic syndrome (HES) differs from adult HES
    • Katz HT, Haque SJ, Hsieh FH. Pediatric hypereosinophilic syndrome (HES) differs from adult HES. J Pediatr 2005; 146:134-136.
    • (2005) J Pediatr , vol.146 , pp. 134-136
    • Katz, H.T.1    Haque, S.J.2    Hsieh, F.H.3
  • 13
    • 29144524525 scopus 로고    scopus 로고
    • Idiopathic hypereosinophilic syndrome in children: Report of a 7-year-old boy with FIP1L1-PDGFRA rearrangement
    • Rives S, Alcorta I, Toll T, et al. Idiopathic hypereosinophilic syndrome in children: report of a 7-year-old boy with FIP1L1-PDGFRA rearrangement. J Pediatr Hematol Oncol 2005; 27:663-665.
    • (2005) J Pediatr Hematol Oncol , vol.27 , pp. 663-665
    • Rives, S.1    Alcorta, I.2    Toll, T.3
  • 14
    • 33646450121 scopus 로고    scopus 로고
    • Hypereosinophilic syndrome: Lymphoproliferative and myeloproliferative variants
    • Roufosse F, Goldman M, Cogan E. Hypereosinophilic syndrome: lymphoproliferative and myeloproliferative variants. Semin Respir Crit Care Med 2006; 27:158-170.
    • (2006) Semin Respir Crit Care Med , vol.27 , pp. 158-170
    • Roufosse, F.1    Goldman, M.2    Cogan, E.3
  • 15
    • 0344325031 scopus 로고
    • Eosinophilic leukemia: A morphologic and histochemical study
    • Ackerman GA. Eosinophilic leukemia: a morphologic and histochemical study. Blood 1964; 24:372-388.
    • (1964) Blood , vol.24 , pp. 372-388
    • Ackerman, G.A.1
  • 16
    • 0017259825 scopus 로고
    • Eosinophil kinetics in the hypereosinophilic syndrome
    • Dale DC, Hubert RT, Fauci A. Eosinophil kinetics in the hypereosinophilic syndrome. J Lab Clin Med 1976; 87:487-495.
    • (1976) J Lab Clin Med , vol.87 , pp. 487-495
    • Dale, D.C.1    Hubert, R.T.2    Fauci, A.3
  • 17
    • 0019840413 scopus 로고
    • A clinicopathologic correlation of the idiopathic hypereosinophilic syndrome. II. Clinical manifestations
    • Schooley RT, Flaum MA, Gralnick HR, Fauci AS. A clinicopathologic correlation of the idiopathic hypereosinophilic syndrome. II. Clinical manifestations. Blood 1981; 58:1021-1026.
    • (1981) Blood , vol.58 , pp. 1021-1026
    • Schooley, R.T.1    Flaum, M.A.2    Gralnick, H.R.3    Fauci, A.S.4
  • 18
    • 0344987881 scopus 로고    scopus 로고
    • A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome
    • Cools J, DeAngelo DJ, Gotlib J, et al. A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome. N Engl J Med 2003; 348:1201-1214.
    • (2003) N Engl J Med , vol.348 , pp. 1201-1214
    • Cools, J.1    DeAngelo, D.J.2    Gotlib, J.3
  • 19
    • 4243139496 scopus 로고    scopus 로고
    • Relationship between idiopathic hypereosinophilic syndrome, eosinophilic leukemia, and systemic mastocytosis
    • Bain BJ. Relationship between idiopathic hypereosinophilic syndrome, eosinophilic leukemia, and systemic mastocytosis. Am J Hematol 2004; 77:82-85.
    • (2004) Am J Hematol , vol.77 , pp. 82-85
    • Bain, B.J.1
  • 20
    • 34548525771 scopus 로고    scopus 로고
    • Chronic eosinophilic leukemias and the myeloproliferative variant of the hypereosinophilic syndrome
    • An excellent review of the contemporary thinking of overlap between chronic eosinophilic leukemias and HES, with particular attention on the FIP1L1 -PDGFRα mutation positive variant of M-HES
    • Bain BJ, Fletcher SH. Chronic eosinophilic leukemias and the myeloproliferative variant of the hypereosinophilic syndrome. Immunol Allergy Clin North Am 2007; 27:377-388. An excellent review of the contemporary thinking of overlap between chronic eosinophilic leukemias and HES, with particular attention on the FIP1L1 -PDGFRα mutation positive variant of M-HES.
    • (2007) Immunol Allergy Clin North Am , vol.27 , pp. 377-388
    • Bain, B.J.1    Fletcher, S.H.2
  • 21
    • 0038792233 scopus 로고    scopus 로고
    • Elevated serum tryptase levels identify a subset of patients with a myeloproliferative variant of idiopathic hypereosinophilic syndrome associated with tissue fibrosis, poor prognosis, and imatinib responsiveness
    • Klion AD, Noel P, Akin C, et al. Elevated serum tryptase levels identify a subset of patients with a myeloproliferative variant of idiopathic hypereosinophilic syndrome associated with tissue fibrosis, poor prognosis, and imatinib responsiveness. Blood 2003; 101:4660-4666.
    • (2003) Blood , vol.101 , pp. 4660-4666
    • Klion, A.D.1    Noel, P.2    Akin, C.3
  • 22
    • 34548537191 scopus 로고    scopus 로고
    • Mechanisms of eosinophilia in the pathogenesis of hypereosinophilic disorders
    • Ackerman SJ, Bochner BS. Mechanisms of eosinophilia in the pathogenesis of hypereosinophilic disorders. Immunol Allergy Clin North Am 2007; 27: 357-375.
    • (2007) Immunol Allergy Clin North Am , vol.27 , pp. 357-375
    • Ackerman, S.J.1    Bochner, B.S.2
  • 23
    • 8644263305 scopus 로고    scopus 로고
    • FIP1L1-PDGFRA fusion: Prevalence and clinicopathologic correlates in 89 consecutive patients with moderate to severe eosinophilia
    • Pardanani A, Brockman SR, Paternoster SF, et al. FIP1L1-PDGFRA fusion: prevalence and clinicopathologic correlates in 89 consecutive patients with moderate to severe eosinophilia. Blood 2004; 104:3038-3045.
    • (2004) Blood , vol.104 , pp. 3038-3045
    • Pardanani, A.1    Brockman, S.R.2    Paternoster, S.F.3
  • 24
    • 0023568002 scopus 로고
    • T lymphocyte control of human eosinophilic granulopoiesis. Clonal analysis in an idiopathic hypereosinophilic syndrome
    • Raghavachar A, Fleischer S, Frickhofen N, et al. T lymphocyte control of human eosinophilic granulopoiesis. Clonal analysis in an idiopathic hypereosinophilic syndrome. J Immunol 1987; 139:3753-3758.
    • (1987) J Immunol , vol.139 , pp. 3753-3758
    • Raghavachar, A.1    Fleischer, S.2    Frickhofen, N.3
  • 25
    • 0027856017 scopus 로고
    • Interleukin-5 is the predominant eosinophilopoietin produced by cloned T lymphocytes in hypereosinophilic syndrome
    • Schrezenmeier H, Thome SD, Tewald F, et al. Interleukin-5 is the predominant eosinophilopoietin produced by cloned T lymphocytes in hypereosinophilic syndrome. Exp Hematol 1993; 21:358-365.
    • (1993) Exp Hematol , vol.21 , pp. 358-365
    • Schrezenmeier, H.1    Thome, S.D.2    Tewald, F.3
  • 26
    • 0027958133 scopus 로고
    • Brief report: Clonal proliferation of type 2 helper T cells in a man with the hypereosinophilic syndrome
    • Cogan E, Schandene L, Crusiaux A, et al. Brief report: clonal proliferation of type 2 helper T cells in a man with the hypereosinophilic syndrome. N Engl J Med 1994; 330:535-538.
    • (1994) N Engl J Med , vol.330 , pp. 535-538
    • Cogan, E.1    Schandene, L.2    Crusiaux, A.3
  • 27
    • 3042742422 scopus 로고    scopus 로고
    • Recent advances in pathogenesis and management of hypereosinophilic syndromes
    • Roufosse F, Cogan E, Goldman M. Recent advances in pathogenesis and management of hypereosinophilic syndromes. Allergy 2004; 59:673-689.
    • (2004) Allergy , vol.59 , pp. 673-689
    • Roufosse, F.1    Cogan, E.2    Goldman, M.3
  • 28
    • 0344809973 scopus 로고    scopus 로고
    • Abnormal clones of T cells producing interleukin-5 in idiopathic eosinophilia
    • Simon HU, Plotz SG, Dummer R, Blaser K. Abnormal clones of T cells producing interleukin-5 in idiopathic eosinophilia. N Engl J Med 1999; 341:1112-1120.
    • (1999) N Engl J Med , vol.341 , pp. 1112-1120
    • Simon, H.U.1    Plotz, S.G.2    Dummer, R.3    Blaser, K.4
  • 29
    • 0042784918 scopus 로고    scopus 로고
    • Clonal Th2 lymphocytes in patients with the idiopathic hypereosinophilic syndrome
    • Roufosse F, Schandene L, Sibille C, et al. Clonal Th2 lymphocytes in patients with the idiopathic hypereosinophilic syndrome. Br J Haematol 2000; 109:540-548.
    • (2000) Br J Haematol , vol.109 , pp. 540-548
    • Roufosse, F.1    Schandene, L.2    Sibille, C.3
  • 30
    • 0037596569 scopus 로고    scopus 로고
    • Discovery of a fusion kinase in EOL-1 cells and idiopathic hypereosinophilic syndrome
    • Griffin JH, Leung J, Bruner RJ, et al. Discovery of a fusion kinase in EOL-1 cells and idiopathic hypereosinophilic syndrome. Proc Natl Acad Sci U S A 2003; 100:7830-7835.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 7830-7835
    • Griffin, J.H.1    Leung, J.2    Bruner, R.J.3
  • 31
    • 34548575072 scopus 로고    scopus 로고
    • Ogbogu PU, Rosing DR, Horne MK 3rd. Cardiovascular manifestations of hypereosinophilic syndromes. Immunol Allergy Clin North Am 2007; 27:457-475. Comprehensive review of the forms of cardiovascular involvement in HES, with discussion of implications for therapy.
    • Ogbogu PU, Rosing DR, Horne MK 3rd. Cardiovascular manifestations of hypereosinophilic syndromes. Immunol Allergy Clin North Am 2007; 27:457-475. Comprehensive review of the forms of cardiovascular involvement in HES, with discussion of implications for therapy.
  • 32
    • 38849127394 scopus 로고    scopus 로고
    • Gertz MA. Troponin in hematologic oncology. Leuk Lymphoma 2008; 49:194-203. This is the first review to discuss the role of measurement of troponin level in blood to assess myocardial involvement in HES.
    • Gertz MA. Troponin in hematologic oncology. Leuk Lymphoma 2008; 49:194-203. This is the first review to discuss the role of measurement of troponin level in blood to assess myocardial involvement in HES.
  • 33
    • 34548477223 scopus 로고    scopus 로고
    • Approach to the therapy of hypereosinophilic syndromes
    • Klion AD. Approach to the therapy of hypereosinophilic syndromes. Immunol Allergy Clin North Am 2007; 27:551-560.
    • (2007) Immunol Allergy Clin North Am , vol.27 , pp. 551-560
    • Klion, A.D.1
  • 34
    • 34548481091 scopus 로고    scopus 로고
    • Novel approaches to therapy of hypereosinophilic syndromes
    • Simon HU, Cools J. Novel approaches to therapy of hypereosinophilic syndromes. Immunol Allergy Clin North Am 2007; 27:519-527.
    • (2007) Immunol Allergy Clin North Am , vol.27 , pp. 519-527
    • Simon, H.U.1    Cools, J.2
  • 35
    • 36348993783 scopus 로고    scopus 로고
    • Relapse following discontinuation of imatinib mesylate therapy for FIP1L1/PDGFRA-positive chronic eosinophilic leukemia: Implications for optimal dosing
    • One of the first studies to discuss optimal dosing of imatinib for FIP1L1/PDGFRA-positive CEL/HES, which will likely lead to further studies along these lines
    • Klion AD, Robyn J, Maric I, et al. Relapse following discontinuation of imatinib mesylate therapy for FIP1L1/PDGFRA-positive chronic eosinophilic leukemia: implications for optimal dosing. Blood 2007; 110:3552-3556. One of the first studies to discuss optimal dosing of imatinib for FIP1L1/PDGFRA-positive CEL/HES, which will likely lead to further studies along these lines.
    • (2007) Blood , vol.110 , pp. 3552-3556
    • Klion, A.D.1    Robyn, J.2    Maric, I.3
  • 36
    • 40949147830 scopus 로고    scopus 로고
    • A single weekly dose of imatinib is sufficient to induce and maintain remission of chronic eosinophilic leukaemia in FIP1L1-PDGFRA-expressing patients
    • Helbig G, Stella-Holowiecka B, Majewski M, et al. A single weekly dose of imatinib is sufficient to induce and maintain remission of chronic eosinophilic leukaemia in FIP1L1-PDGFRA-expressing patients. Br J Haematol 2008; 141:200-204.
    • (2008) Br J Haematol , vol.141 , pp. 200-204
    • Helbig, G.1    Stella-Holowiecka, B.2    Majewski, M.3
  • 37
    • 0942276859 scopus 로고    scopus 로고
    • Molecular remission and reversal of myelofibrosis in response to imatinib mesylate treatment in patients with the myeloproliferative variant of hypereosinophilic syndrome
    • Klion AD, Robyn J, Akin C, et al. Molecular remission and reversal of myelofibrosis in response to imatinib mesylate treatment in patients with the myeloproliferative variant of hypereosinophilic syndrome. Blood 2004; 103:473-478.
    • (2004) Blood , vol.103 , pp. 473-478
    • Klion, A.D.1    Robyn, J.2    Akin, C.3
  • 38
    • 0030040423 scopus 로고    scopus 로고
    • Recombinant interferon-alpha selectively inhibits the production of interleukin-5 by human CD4+ T cells
    • Schandene L, Del Prete GF, Cogan E, et al. Recombinant interferon-alpha selectively inhibits the production of interleukin-5 by human CD4+ T cells. J Clin Invest 1996; 97:309-315.
    • (1996) J Clin Invest , vol.97 , pp. 309-315
    • Schandene, L.1    Del Prete, G.F.2    Cogan, E.3
  • 39
    • 0034672270 scopus 로고    scopus 로고
    • Interferon alpha prevents spontaneous apoptosis of clonal Th2 cells associated with chronic hypereosinophilia
    • Schandene L, Roufosse F, de Lavareille A, et al. Interferon alpha prevents spontaneous apoptosis of clonal Th2 cells associated with chronic hypereosinophilia. Blood 2000; 96:4285-4292.
    • (2000) Blood , vol.96 , pp. 4285-4292
    • Schandene, L.1    Roufosse, F.2    de Lavareille, A.3
  • 41
    • 40949146020 scopus 로고    scopus 로고
    • Rothenberg ME, Klion AD, Roufosse FE, et al. Treatment of patients with the hypereosinophilic syndrome with mepolizumab. N Engl J Med 2008; 358:1215-1228. Report of the most comprehensive study of a monoclonal antibody to IL-5, which describes efficacy as a steroid-sparing agent for non FIP1L1/PDGFRA HES.
    • Rothenberg ME, Klion AD, Roufosse FE, et al. Treatment of patients with the hypereosinophilic syndrome with mepolizumab. N Engl J Med 2008; 358:1215-1228. Report of the most comprehensive study of a monoclonal antibody to IL-5, which describes efficacy as a steroid-sparing agent for non FIP1L1/PDGFRA HES.
  • 42
    • 44649103777 scopus 로고    scopus 로고
    • Stein ML, Villanueva JM, Buckmeier BK, et al. Anti-IL-5 (mepolizumab) therapy reduces eosinophil activation ex vivo and increases IL-5 and IL-5 receptor levels. J Allergy Clin Immunol 2008; 121:1473-1483; 1483 e1471-1474. A groundbreaking study, shedding light on the mechanisms of action and efficacy of this monoclonal antibody to IL-5.
    • Stein ML, Villanueva JM, Buckmeier BK, et al. Anti-IL-5 (mepolizumab) therapy reduces eosinophil activation ex vivo and increases IL-5 and IL-5 receptor levels. J Allergy Clin Immunol 2008; 121:1473-1483; 1483 e1471-1474. A groundbreaking study, shedding light on the mechanisms of action and efficacy of this monoclonal antibody to IL-5.
  • 43
    • 10344259603 scopus 로고    scopus 로고
    • Alemtuzumab therapy for refractory idiopathic hypereosinophilic syndrome with abnormal T cells: A case report
    • Pitini V, Teti D, Arrigo C, Righi M. Alemtuzumab therapy for refractory idiopathic hypereosinophilic syndrome with abnormal T cells: a case report. Br J Haematol 2004; 127:477.
    • (2004) Br J Haematol , vol.127 , pp. 477
    • Pitini, V.1    Teti, D.2    Arrigo, C.3    Righi, M.4
  • 44
    • 1242338010 scopus 로고    scopus 로고
    • Alemtuzumab therapy for refractory idiopathic hypereosinophilic syndrome
    • Sefcick A, Sowter D, DasGupta E, et al. Alemtuzumab therapy for refractory idiopathic hypereosinophilic syndrome. Br J Haematol 2004; 124:558-559.
    • (2004) Br J Haematol , vol.124 , pp. 558-559
    • Sefcick, A.1    Sowter, D.2    DasGupta, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.