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2 Yamada T, Shinohara K, Katsuki K: A case of idiopathic hypereosinophilic syndrome complicated with disseminated intravascular coagulation. Am J Hematol 1998, 58:100-101.
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4 Chang H-W, Leong K-H, Koh D-R, Lee S-H: Clonality of isolated eosinophils in the hypereosinophilic syndrome. Blood 1999, 93:1651-1657. This study demonstrates that investigations of X-linked polymorphisms of the Humara gene can provide evidence of a clonal population of eosinophils in the otherwise unexplained hypereosinophilic syndrome.
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5 Raghavacher A, Fleischer S, Frickhofen N, Heimpel H, Fleischner S: T lymphocyte control of human eosinophilic granulopoiesis: clonal analysis of an idiopathic hypereosinophilic syndrome. J Immunol 1990, 139:3753-3758.
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Clonal proliferation of type 2 helper T cells in a man with hypereosinophilic syndrome
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6 Cogan E, Schandené L, Cogan E, Crusiaux A, Cochaux P, Velu T, Goldman M: Clonal proliferation of type 2 helper T cells in a man with hypereosinophilic syndrome. New Engl J Med 1994, 330:535-538.
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Role of gamma/delta T cells in a patient with CD4+CD3-lymphocytosis, hypereosinophilia, and high levels of IgE
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8 Bank I, Reshef A, Beniaminov M, Rosenthal, E, Rechavi G, Monselise Y: Role of gamma/delta T cells in a patient with CD4+CD3-lymphocytosis, hypereosinophilia, and high levels of IgE. J Allergy Clin Immunol 1998, 102:621-630.
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T-cell receptor-independent activation of clonal Th2 cells associated with chronic hypereosinophilia
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9 Roufosse F, Schandene L, Sibille C, Kennes B, Efira A, Cogan E, Goldman M: T-cell receptor-independent activation of clonal Th2 cells associated with chronic hypereosinophilia. Blood 1999, 94:994-1002. This investigation established that in some cases neoplastic T cell clones synthesizing IL-5 and giving rise to hypereosinophilia are not autonomous but require signaling through accessory cells.
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11
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Fusion of PDGF receptor β to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation
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11 Golub TR, Barker GF, Lovett M, Gilliland DG: Fusion of PDGF receptor β to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation. Cell 1994, 77:307-316.
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TEL/PDGFβR induces hematologic malignancies in mice that respond to a specific tyrosine kinase inhibitor
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12 Tomasson MH, Williams IR, Hasserjian R, Udomsakhdi C, McGrath SM, Schwaller J, et al.: TEL/PDGFβR induces hematologic malignancies in mice that respond to a specific tyrosine kinase inhibitor. Blood 1999, 93:1707-1714. This paper presents evidence that a fusion gene implicated in chronic eosinophilic leukemia is oncogenic in transgenic mice.
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Mechanism of Tel/PDGFRβ mediated myeloproliferation in transgenic mice
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13 Aprikian AG, Montgomery B, Bowen-Pope DF, Hickstein DD: Mechanism of Tel/PDGFRβ mediated myeloproliferation in transgenic mice [abstract]. Blood 1997, 90(Suppl 1):412. This paper presents evidence that a fusion gene implicated in chronic eosinophilic leukemia is oncogenic in transgenic mice.
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Aprikian, A.G.1
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0030852328
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Fusion of TEL, the ETS variant gene 6 (ETV6) to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia
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14 Peeters P, Raynaud SD, Cools J, Wlodarska I, Grosgeorge J, Philip P, et al.: Fusion of TEL, the ETS variant gene 6 (ETV6) to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia, Blood 1997, 90:2535-2540.
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15
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FGFR1 is fused with a novel zinc-finger gene, ZNF198, in the t(8;13) leukaemia/lymphoma syndrome
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15 Xiao S, Nalbolu SR, Aster JC, Ma J, Abruzzo L, Jaffe ES, et al.: FGFR1 is fused with a novel zinc-finger gene, ZNF198, in the t(8;13) leukaemia/lymphoma syndrome. Nature Genetics 1998, 18:84-87. This report establishes that in this stem cell myeloproliferative disorder, fusion of a putative oncogene, FGFR1, occurs with a unique partner gene. Abnormal signal transduction is likely to contribute to oncogenesis.
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16
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0009014253
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Fibroblast growth factor receptor 1 is fused to different unrelated genes in stem cell myeloproliferative disorder linked to 8p11-12 chromosomal region
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16 Pebusque MJ, Popovici C, Guasch G, Adélaide J, Chaffanet M, Zhang B, et al.: Fibroblast growth factor receptor 1 is fused to different unrelated genes in stem cell myeloproliferative disorder linked to 8p11-12 chromosomal region [abstract]. Blood 1998, 92(Suppl 1):594. This report establishes that in this stem cell myeloproliferative disorder, fusion of a putative oncogene, FGFR1, occurs with a unique partner gene. Abnormal signal transduction is likely to contribute to oncogenesis.
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17
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0033558253
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The t(6;8) (q27;p11) translocation in a stem cell myeloproliferative disorder fuses a novel gene, FOP, to fibroblast growth factor receptor 1
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17 Popovici C, Zhang B, Grégoire M-J, Jonveaux P, Lafage-Pochitaloff M, Birnbaum D, Pébusque M-J: The t(6;8) (q27;p11) translocation in a stem cell myeloproliferative disorder fuses a novel gene, FOP, to Fibroblast Growth Factor receptor 1. Blood 1999, 93:1381-1389. This report establishes that in this stem cell myeloproliferative disorder, fusion of a putative oncogene, FGFR1, occurs with a unique partner gene. Abnormal signal transduction is likely to contribute to oncogenesis.
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18
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Myc is essential for transformation by TL/platelet-derived growth factor receptor β (PDGFRβ)
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18 Bourgeade M-F, Défachelles AS, Cayre YE: Myc is essential for transformation by TL/platelet-derived growth factor receptor β (PDGFRβ). Blood 1999, 91:3333-3339.
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19
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0032403423
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Late appearance of t(5;12) (q31;p12) in acute myeloid leukemia associated with eosinophilia
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19 Yahata N, Ohyashiki K, Ohyashiki JH, Kimura Y, Miyazawa K, Kodama A, et al.: Late appearance of t(5;12) (q31;p12) in acute myeloid leukemia associated with eosinophilia. Cancer Genet Cytogenet 1998: 107,147-150.
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20
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Fluorescent in situ hybridization characterisation of new translocations involving TEL (ETV6) in a wide range of hematologic malignancies
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20 Wlodarska I, La Starza R, Baens M, Dierlamm J, Uyttebroeck A, Selleslag D, et al.: Fluorescent in situ hybridization characterisation of new translocations involving TEL (ETV6) in a wide range of hematologic malignancies. Blood 1998, 91:1399-1406.
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21
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0031860817
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Cytogenetic response induced by interferon alpha in the myeloproliferative disorder with eosinophilia, T cell lymphoma and the chromosomal translocation t(8;13) (p11;q12)
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21 Martinez-Climent JA, Vizcarra E, Benet I, Marugan I, Terol MJ, Solano C, et al.: Cytogenetic response induced by interferon alpha in the myeloproliferative disorder with eosinophilia, T cell lymphoma and the chromosomal translocation t(8;13) (p11;q12). Leukemia 1998, 12:999-1000.
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22 Follows GA, Owen RG, Ashcroft AJ, Parapia LA: Eosinophilic myelodysplasia transforming to acute lymphoblastic leukaemia. J Clin Pathol 1999, 52:388-389.
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23
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0002129360
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A myeloproliferative disorder with eosinophilia, a translocation t(8;9) (p22;23) and a cerebellar degeneration in regression with interferon alpha therapy
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23 Vandergoten P, Janssen M, Madoe V, Vanstraelen D: A myeloproliferative disorder with eosinophilia, a translocation t(8;9) (p22;23) and a cerebellar degeneration in regression with interferon alpha therapy [abstract]. Acta Haematol 1998, 100(Suppl 1):8.
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24 Yamada O, Kitahara K, Imamura K, Ozasa H, Okada M, Mizoguchi H: Clinical and cytogenetic remission induced by interferon-α in a patient with chronic eosinophilic leukemia associated with a unique t(3;9;5) translocation. Am J Hematol 1998,58:137-141.
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Further evidence for the clonal nature of the idiopathic hypereosinophilic syndrome: Complete remission induced by interferon-alpha in a case with a unique chromosomal abnormality
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29 Forrest DL, Horsman DE, Jensen CL, Berry BR, Dalal BI, Barnett MJ, Nantel SH: Myelodysplastic syndrome with hypereosinophilia and a nonrandom chromosomal abnormality dic(1;7): confirmation of eosinophil clonal involvement by fluorescent in situ hybridization. Cancer Genet Cytogenet 1998, 107:65-68.
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