메뉴 건너뛰기




Volumn 29, Issue 1, 2004, Pages 51-56

Up-regulation of μ-opioid receptors in the spinal cord of morphine-tolerant rats

Author keywords

Autoradiography; Morphine; Tolerance; Up regulation; receptor

Indexed keywords

ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; MORPHINE; MU OPIATE RECEPTOR;

EID: 1842579036     PISSN: 02505991     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf02702561     Document Type: Article
Times cited : (21)

References (27)
  • 1
    • 0037154878 scopus 로고    scopus 로고
    • Up-regulation of central μ-opioid receptors in a model of hepatic encephalopathy: A potential mechanism for increased sensitivity to morphine in liver failure
    • Bergasa N V, Rothman R B, Mukerjee E, Vergalla J and Jones E A 2002 Up-regulation of central μ-opioid receptors in a model of hepatic encephalopathy: a potential mechanism for increased sensitivity to morphine in liver failure; Life Sci. 70 1701-1708
    • (2002) Life Sci. , vol.70 , pp. 1701-1708
    • Bergasa, N.V.1    Rothman, R.B.2    Mukerjee, E.3    Vergalla, J.4    Jones, E.A.5
  • 2
    • 0032052168 scopus 로고    scopus 로고
    • μ-Opioid receptor downregulation and cAMP-dependent protein kinase phosphorylation in a mouse model of chronic morphine tolerance
    • Bernstein M A and Welch S P 1998 μ-Opioid receptor downregulation and cAMP-dependent protein kinase phosphorylation in a mouse model of chronic morphine tolerance; Brain Res. Mol. Brain Res. 55 237-242
    • (1998) Brain Res. Mol. Brain Res. , vol.55 , pp. 237-242
    • Bernstein, M.A.1    Welch, S.P.2
  • 3
    • 0026612289 scopus 로고
    • 3H]DTLET opioid binding sites in laminae I-II of the spinal cord in intact and deafferented morphine-tolerant rats
    • 3H]DTLET opioid binding sites in laminae I-II of the spinal cord in intact and deafferented morphine-tolerant rats; Neurosci. Lett. 136 209-212
    • (1992) Neurosci. Lett. , vol.136 , pp. 209-212
    • Besse, D.1    Lombard, M.C.2    Besson, J.M.3
  • 4
    • 0025307494 scopus 로고
    • Pre- and postsynaptic distribution of μ-, δ- and κ-opioid receptors in the superficial layers of the cervical dorsal horn of the rat spinal cord
    • Besse D, Lombard M C, Zajac J M, Roques B P and Besson J M 1990 Pre- and postsynaptic distribution of μ-, δ- and κ-opioid receptors in the superficial layers of the cervical dorsal horn of the rat spinal cord; Brain Res. 521 15-22
    • (1990) Brain Res. , vol.521 , pp. 15-22
    • Besse, D.1    Lombard, M.C.2    Zajac, J.M.3    Roques, B.P.4    Besson, J.M.5
  • 5
    • 0025185668 scopus 로고
    • Down-regulation of brain and spinal cord μ-opiate receptors in morphine tolerant-dependent rats
    • Bhargava H N and Gulati A 1990 Down-regulation of brain and spinal cord μ-opiate receptors in morphine tolerant-dependent rats; Eur. J. Pharmacol. 190 305-311
    • (1990) Eur. J. Pharmacol. , vol.190 , pp. 305-311
    • Bhargava, H.N.1    Gulati, A.2
  • 6
    • 0034619796 scopus 로고    scopus 로고
    • μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence
    • Bohn L M, Gainetdinov R R, Lin F T, Lefkowitz R J and Caron M G 2000 μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence; Nature (London) 408 720-723
    • (2000) Nature (London) , vol.408 , pp. 720-723
    • Bohn, L.M.1    Gainetdinov, R.R.2    Lin, F.T.3    Lefkowitz, R.J.4    Caron, M.G.5
  • 7
    • 0024552044 scopus 로고
    • Chronic morphine increases μ-opiate receptor binding in rat brain: A quantitative autoradiographic study
    • Brady L S, Herkenham M, Long J B and Rothman R B 1989 Chronic morphine increases μ-opiate receptor binding in rat brain: a quantitative autoradiographic study; Brain Res. 477 382-386
    • (1989) Brain Res. , vol.477 , pp. 382-386
    • Brady, L.S.1    Herkenham, M.2    Long, J.B.3    Rothman, R.B.4
  • 8
    • 0033874470 scopus 로고    scopus 로고
    • Autoradiographic mapping of μ-opioid receptors during opiate tolerance and supersensitivity in the rat central nervous system
    • Diaz A, Pazos A, Florez J and Hurle M A 2000 Autoradiographic mapping of μ-opioid receptors during opiate tolerance and supersensitivity in the rat central nervous system; Naunyn Schmiedebergs Arch. Pharmacol. 362 101-109
    • (2000) Naunyn Schmiedebergs Arch. Pharmacol. , vol.362 , pp. 101-109
    • Diaz, A.1    Pazos, A.2    Florez, J.3    Hurle, M.A.4
  • 9
    • 0018612302 scopus 로고
    • In vivo opiate binding unchanged in tolerant/dependent mice
    • Dum J, Meyer G, Hollt V and Herz A 1979 In vivo opiate binding unchanged in tolerant/dependent mice; Eur. J. Pharmacol. 58 453-460
    • (1979) Eur. J. Pharmacol. , vol.58 , pp. 453-460
    • Dum, J.1    Meyer, G.2    Hollt, V.3    Herz, A.4
  • 10
    • 84935383230 scopus 로고
    • Synthetic analgesics: II. Dithenylbutenyl and dithienyl-butylamines
    • Eddy N B and Leimbach D 1953 Synthetic analgesics: II. Dithenylbutenyl and dithienyl-butylamines; J. Pharmacol. Exp. Ther. 107 385-393
    • (1953) J. Pharmacol. Exp. Ther. , vol.107 , pp. 385-393
    • Eddy, N.B.1    Leimbach, D.2
  • 11
    • 0036078549 scopus 로고    scopus 로고
    • Chronic morphine-induced changes in μ-opioid receptors and G proteins of different subcellular loci in rat brain
    • Fabian G, Bozo B, Szikszay M, Horvath G, Coscia C J and Szucs M 2002 Chronic morphine-induced changes in μ-opioid receptors and G proteins of different subcellular loci in rat brain; J. Pharmacol. Exp. Ther. 302 774-780
    • (2002) J. Pharmacol. Exp. Ther. , vol.302 , pp. 774-780
    • Fabian, G.1    Bozo, B.2    Szikszay, M.3    Horvath, G.4    Coscia, C.J.5    Szucs, M.6
  • 12
    • 0022501341 scopus 로고
    • Action at the μ-receptor is sufficient to explain the supraspinal analgesic effect of opiates
    • Fang F G, Fields H L and Lee N M 1986 Action at the μ-receptor is sufficient to explain the supraspinal analgesic effect of opiates; J. Pharmacol. Exp. Ther. 238 1039-1044
    • (1986) J. Pharmacol. Exp. Ther. , vol.238 , pp. 1039-1044
    • Fang, F.G.1    Fields, H.L.2    Lee, N.M.3
  • 14
    • 0027225219 scopus 로고
    • Opioid and substance P receptor adaptations in the rat spinal cord following sub-chronic intrathecal treatment with morphine and naloxone
    • Gouarderes C, Jhamandas K, Cridland R, Cros J, Quirion R and Zajac J M 1993 Opioid and substance P receptor adaptations in the rat spinal cord following sub-chronic intrathecal treatment with morphine and naloxone; Neuroscience 54 799-807
    • (1993) Neuroscience , vol.54 , pp. 799-807
    • Gouarderes, C.1    Jhamandas, K.2    Cridland, R.3    Cros, J.4    Quirion, R.5    Zajac, J.M.6
  • 15
    • 1842545033 scopus 로고    scopus 로고
    • Up-regulation of μ-opioid receptors in the spinal cord of morphine tolerant rats
    • San Diego, USA (abstract no. 1534-P82)
    • Gupta H, Gupta Y K and Ray S B 2002 Up-regulation of μ-opioid receptors in the spinal cord of morphine tolerant rats; Proceedings of the 10th World Congress on Pain, San Diego, USA (abstract no. 1534-P82)
    • (2002) Proceedings of the 10th World Congress on Pain
    • Gupta, H.1    Gupta, Y.K.2    Ray, S.B.3
  • 16
    • 0020331617 scopus 로고
    • The role of endorphins in stress-induced analgesia
    • Kelly D D 1982 The role of endorphins in stress-induced analgesia; Ann. N.Y. Acad. Sci. 398 260-271
    • (1982) Ann. N.Y. Acad. Sci. , vol.398 , pp. 260-271
    • Kelly, D.D.1
  • 17
    • 0030298514 scopus 로고    scopus 로고
    • The μ-opioid receptor (MOR1) is mainly restricted to neurons that do not contain GABA or glycine in the superficial dorsal horn of the rat spinal cord
    • Kemp T, Spike R C, Watt C and Todd A J 1996 The μ-opioid receptor (MOR1) is mainly restricted to neurons that do not contain GABA or glycine in the superficial dorsal horn of the rat spinal cord; Neuroscience 75 1231-1238
    • (1996) Neuroscience , vol.75 , pp. 1231-1238
    • Kemp, T.1    Spike, R.C.2    Watt, C.3    Todd, A.J.4
  • 18
    • 0021672157 scopus 로고
    • Acute systemic administration of morphine selectively increases μ-opioid receptor binding in the rat brain
    • Lewis J W, Lewis M E, Loomus D J and Akil H 1984 Acute systemic administration of morphine selectively increases μ-opioid receptor binding in the rat brain; Neuropeptides 5 117-120
    • (1984) Neuropeptides , vol.5 , pp. 117-120
    • Lewis, J.W.1    Lewis, M.E.2    Loomus, D.J.3    Akil, H.4
  • 19
    • 0000751786 scopus 로고
    • Opioid actions on membrane ion channels
    • (eds) A Herz, H Akil and E Simon (Berlin: Springer)
    • North R A 1993 Opioid actions on membrane ion channels; in Handbook of experimental pharmacology: opioids I (eds) A Herz, H Akil and E Simon (Berlin: Springer) pp 773-779
    • (1993) Handbook of Experimental Pharmacology: Opioids I , pp. 773-779
    • North, R.A.1
  • 20
    • 0017275905 scopus 로고
    • Opiate receptor binding-enhancement by opiate administration in vivo
    • Pert C B and Snyder S H 1976 Opiate receptor binding-enhancement by opiate administration in vivo; Biochem. Pharmacol. 25 847-853
    • (1976) Biochem. Pharmacol , vol.25 , pp. 847-853
    • Pert, C.B.1    Snyder, S.H.2
  • 21
    • 0344686599 scopus 로고    scopus 로고
    • μ-Opioid receptors in the cervical region of the spinal cord of adult rat
    • Ray S B 1996 μ-Opioid receptors in the cervical region of the spinal cord of adult rat; Ann. Natl. Acad. Med. Sci. India 32 59-62
    • (1996) Ann. Natl. Acad. Med. Sci. India. , vol.32 , pp. 59-62
    • Ray, S.B.1
  • 22
    • 0032766520 scopus 로고    scopus 로고
    • μ-Opioid receptors in developing human spinal cord
    • Ray S B and Wadhwa S 1999 μ-Opioid receptors in developing human spinal cord; J. Anat. 195 11-18
    • (1999) J. Anat. , vol.195 , pp. 11-18
    • Ray, S.B.1    Wadhwa, S.2
  • 23
    • 0036139108 scopus 로고    scopus 로고
    • Morphine tolerance in spinal cord is due to interaction between μ- and δ-receptors
    • Riba P, Ben Y, Smith A P, Furst S and Lee N M 2002 Morphine tolerance in spinal cord is due to interaction between μ- and δ-receptors; J. Pharmacol. Exp. Ther. 300 265-272
    • (2002) J. Pharmacol. Exp. Ther. , vol.300 , pp. 265-272
    • Riba, P.1    Ben, Y.2    Smith, A.P.3    Furst, S.4    Lee, N.M.5
  • 24
    • 0025973149 scopus 로고
    • Upregulation of the opioid receptor complex by the chronic administration of morphine: A biochemical marker related to the development of tolerance and dependence
    • Rothman R B, Long J B, Bykov V, Xu H, Jacobson A E, Rice K C and Holaday J W 1991 Upregulation of the opioid receptor complex by the chronic administration of morphine: a biochemical marker related to the development of tolerance and dependence; Peptides 12 151-160
    • (1991) Peptides , vol.12 , pp. 151-160
    • Rothman, R.B.1    Long, J.B.2    Bykov, V.3    Xu, H.4    Jacobson, A.E.5    Rice, K.C.6    Holaday, J.W.7
  • 25
    • 0023093925 scopus 로고
    • Decrease in δ- and μ-opioid receptor binding capacity in rat brain after chronic etorphine treatment
    • Tao P L, Law P Y and Loh H H 1987 Decrease in δ- and μ-opioid receptor binding capacity in rat brain after chronic etorphine treatment; J. Pharmacol. Exp. Ther. 240 809-816
    • (1987) J. Pharmacol. Exp. Ther. , vol.240 , pp. 809-816
    • Tao, P.L.1    Law, P.Y.2    Loh, H.H.3
  • 26
    • 0027517258 scopus 로고
    • The interaction of the μ-opioid receptor and G protein is altered after chronic morphine treatment in rats
    • Tao P L, Lee C R, Law P Y and Loh H H 1993 The interaction of the μ-opioid receptor and G protein is altered after chronic morphine treatment in rats; Naunyn Schmiedebergs Arch. Pharmacol. 348 504-508
    • (1993) Naunyn Schmiedebergs Arch. Pharmacol. , vol.348 , pp. 504-508
    • Tao, P.L.1    Lee, C.R.2    Law, P.Y.3    Loh, H.H.4
  • 27
    • 0025142226 scopus 로고
    • Decrease in μ-opioid receptor binding capacity in rat brain after chronic PL017 treatment
    • Tao P L, Lee H Y, Chang L R and Loh H H 1990 Decrease in μ-opioid receptor binding capacity in rat brain after chronic PL017 treatment; Brain Res. 526 270-275
    • (1990) Brain Res. , vol.526 , pp. 270-275
    • Tao, P.L.1    Lee, H.Y.2    Chang, L.R.3    Loh, H.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.