-
1
-
-
67649129874
-
-
Seattle, WA: ZymoGenetics Inc
-
Recothrom [package insert]. Seattle, WA: ZymoGenetics Inc; 2008.
-
(2008)
Recothrom [Package Insert]
-
-
-
2
-
-
67649093852
-
-
Somerville, NJ: J&J Wound Management
-
Evithrom [package insert]. Somerville, NJ: J&J Wound Management; 2007.
-
(2007)
Evithrom [Package Insert]
-
-
-
3
-
-
60349093544
-
-
Bristol, VA: Jones Pharma Incorporated
-
Thrombin-JMI [package insert]. Bristol, VA: Jones Pharma Incorporated; 2007.
-
(2007)
Thrombin-JMI [Package Insert]
-
-
-
4
-
-
4344674120
-
Recombinant biologics for treatment of bleeding disorders
-
Bishop P, Lawson J. Recombinant biologics for treatment of bleeding disorders. Nat Rev Drug Discov. 2004; 3(8):684-694. (Pubitemid 39173509)
-
(2004)
Nature Reviews Drug Discovery
, vol.3
, Issue.8
, pp. 684-694
-
-
Bishop, P.1
Lawson, J.2
-
5
-
-
67651121384
-
Protein characterization of recombinant human thrombin and demonstration of efficacy in models of surgical bleeding
-
abstract
-
Bishop P. Protein characterization of recombinant human thrombin and demonstration of efficacy in models of surgical bleeding [abstract]. Blood. 2003;102(11, pt 2):89B.
-
(2003)
Blood
, vol.102
, Issue.11 PART 2
-
-
Bishop, P.1
-
6
-
-
34447629499
-
A Phase 3, Randomized, Double-Blind Comparative Study of the Efficacy and Safety of Topical Recombinant Human Thrombin and Bovine Thrombin in Surgical Hemostasis
-
DOI 10.1016/j.jamcollsurg.2007.03.020, PII S1072751507004565
-
Chapman WC, Singla N, Genyk Y, et al. A phase 3, randomized, double-blind comparative study of the efficacy and safety of topical recombinant human thrombin and bovine thrombin in surgical hemostasis. J Am Coll Surg. 2007;205(2):256-265. (Pubitemid 47095423)
-
(2007)
Journal of the American College of Surgeons
, vol.205
, Issue.2
, pp. 256-265
-
-
Chapman, W.C.1
Singla, N.2
Genyk, Y.3
McNeil, J.W.4
Renkens Jr., K.L.5
Reynolds, T.C.6
Murphy, A.7
Weaver, F.A.8
-
7
-
-
33747160749
-
Phase 2, randomized, double-blind, placebo-controlled, multicenter clinical evaluation of recombinant human thrombin in multiple surgical indications [6]
-
DOI 10.1111/j.1538-7836.2006.02067.x
-
Chapman WC, Lockstadt H, Singla N, Kafie FE, Lawson JH. Phase 2, randomized, double-blind, placebocontrolled, multicenter clinical evaluation of recombinant human thrombin in multiple surgical indications. J Thromb Haemost. 2006;4(9):2083-2085. (Pubitemid 44226801)
-
(2006)
Journal of Thrombosis and Haemostasis
, vol.4
, Issue.9
, pp. 2083-2085
-
-
Chapman, W.C.1
Lockstadt, H.2
Singla, N.3
Kafie, F.E.4
Lawson, J.H.5
-
8
-
-
33646489465
-
Comparison of recombinant human thrombin and plasma-derived human alpha-thrombin
-
Bishop PD, Lewis KB, Schultz J, Walker KM. Comparison of recombinant human thrombin and plasma-derived human alpha-thrombin. Semin Thromb Hemost. 2006;32(suppl 1):86-97.
-
(2006)
Semin Thromb Hemost
, vol.32
, Issue.SUPPL. 1
, pp. 86-97
-
-
Bishop, P.D.1
Lewis, K.B.2
Schultz, J.3
Walker, K.M.4
-
9
-
-
67651089410
-
Recombinant human thrombin does not contain detectable factor V impurities
-
abstract
-
Rene S, Stamm MR, Greeff K, Walker KM, Raymond F, West RR. Recombinant human thrombin does not contain detectable factor V impurities [abstract]. Pharmacotherapy. 2004;24:1438.
-
(2004)
Pharmacotherapy
, vol.24
, pp. 1438
-
-
Rene, S.1
Stamm, M.R.2
Greeff, K.3
Walker, K.M.4
Raymond, F.5
West, R.R.6
-
10
-
-
33747199879
-
125I]- recombinant human thrombin following intravenous or subcutaneous administration to non-human primates
-
DOI 10.1111/j.1538-7836.2006.02097.x
-
Visich JE, Byrnes-Blake KA, Lewis KB, Meengs B, Rogge MC. Bioavailability and relative tissue distribution of [125I]- recombinant human thrombin following intravenous or subcutaneous administration to non-human primates. J Thromb Haemost. 2006;4(9):1962-1968. (Pubitemid 44226775)
-
(2006)
Journal of Thrombosis and Haemostasis
, vol.4
, Issue.9
, pp. 1962-1968
-
-
Visich, J.E.1
Byrnes-Blake, K.A.2
Lewis, K.B.3
Meengs, B.4
Rogge, M.C.5
-
12
-
-
2542447341
-
Severe coagulopathy following intraoperative use of topical thrombin
-
Sarfati MR, DiLorenzo DJ, Kraiss LW, Galt SW. Severe coagulopathy following intraoperative use of topical thrombin. Ann Vasc Surg. 2004;18(3): 349-351.
-
(2004)
Ann Vasc Surg
, vol.18
, Issue.3
, pp. 349-351
-
-
Sarfati, M.R.1
Dilorenzo, D.J.2
Kraiss, L.W.3
Galt, S.W.4
-
13
-
-
0034492730
-
Exposure to topical bovine thrombin during surgery elicits a response against the xenogeneic carbohydrate Galactose α1-3Galactose
-
DOI 10.1023/A:1026455631876
-
Schoenecker JG, Hauck RK, Mercer MC, Parker W, Lawson JH. Exposure to topical bovine thrombin during surgery elicits a response against the xenogeneic carbohydrate galactose alpha1-3galactose. J Clin Immunol. 2000;20(6):434-444. (Pubitemid 32099708)
-
(2000)
Journal of Clinical Immunology
, vol.20
, Issue.6
, pp. 434-444
-
-
Schoenecker, J.G.1
Hauck, R.K.2
Mercer, M.C.3
Parker, W.4
Lawson, J.H.5
-
14
-
-
0036482878
-
Coagulopathy as a result of factor V inhibitor after exposure to bovine topical thrombin
-
DOI 10.1067/mva.2002.118587
-
Neschis DG, Heyman MR, Cheanvechai V, Benjamin ME, Flinn WR. Coagulopathy as a result of factor V inhibitor after exposure to bovine thrombin. J Vasc Surg. 2002;35(2):400-402. (Pubitemid 44718652)
-
(2002)
Journal of Vascular Surgery
, vol.35
, Issue.2
, pp. 400-402
-
-
Neschis, D.G.1
Heyman, M.R.2
Cheanvechai, V.3
Benjamin, M.E.4
Flinn, W.R.5
-
15
-
-
33751101681
-
Bovine thrombin induces an acquired coagulopathy in sensitized patients undergoing revision spinal surgery: A report of two cases
-
Poynton AR, Nelson MC, McCance SE, Levine RL, O'Leary PF. Bovine thrombin induces an acquired coagulopathy in sensitized patients undergoing revision spinal surgery: a report of two cases. Spine. 2003;28(12):E221-E223.
-
(2003)
Spine
, vol.28
, Issue.12
-
-
Poynton, A.R.1
Nelson, M.C.2
McCance, S.E.3
Levine, R.L.4
O'Leary, P.F.5
-
16
-
-
14244252558
-
Antihuman factor V antibodies after use of relatively pure bovine thrombin
-
Lawson JH, Lynn KA, Vanmatre RM, et al. Antihuman factor V antibodies after use of relatively pure bovine thrombin. Ann Thorac Surg. 2005; 79(3):1037-1038.
-
(2005)
Ann Thorac Surg
, vol.79
, Issue.3
, pp. 1037-1038
-
-
Lawson, J.H.1
Lynn, K.A.2
Vanmatre, R.M.3
-
17
-
-
0035165420
-
Immunologic impact and clinical outcomes after surgical exposure to bovine thrombin
-
Ortel TL, Mercer MC, Thames EH, Moore KD, Lawson JH. Immunologic impact and clinical outcomes after surgical exposure to bovine thrombin. Ann Surg. 2001;233(1):88-96.
-
(2001)
Ann Surg
, vol.233
, Issue.1
, pp. 88-96
-
-
Ortel, T.L.1
Mercer, M.C.2
Thames, E.H.3
Moore, K.D.4
Lawson, J.H.5
-
18
-
-
33646484957
-
The clinical use and immunologic impact of thrombin in surgery
-
Lawson JH. The clinical use and immunologic impact of thrombin in surgery. Semin Thromb Hemost. 2006;32(suppl 1):98-110.
-
(2006)
Semin Thromb Hemost
, vol.32
, Issue.SUPPL. 1
, pp. 98-110
-
-
Lawson, J.H.1
-
19
-
-
67651093630
-
Nonclinical safety and immunogenicity evaluation of repeated subcutaneous administration of rhThrombin
-
abstract
-
Heffernan JK, Wills M, Ponce RA, et al. Nonclinical safety and immunogenicity evaluation of repeated subcutaneous administration of rhThrombin [abstract]. Pharmacotherapy. 2004;24: 1466.
-
(2004)
Pharmacotherapy
, vol.24
, pp. 1466
-
-
Heffernan, J.K.1
Wills, M.2
Ponce, R.A.3
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