Impact of chemokine receptor CCR2 and CCR5 gene polymorphism on allograft outcome in North Indian renal transplant recipients

Scandinavian Journal of Immunology

Volumn 69, Issue 1, 2009, Pages 51-56

  Singh, R ^a   Kapoor, R ^a   Srivastava, A ^a   Mittal, R D ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR5;

ADULT; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GRAFT RECIPIENT; HUMAN; INDIAN; KIDNEY ALLOGRAFT; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

ADULT; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GRAFT REJECTION; HUMANS; INDIA; KIDNEY TRANSPLANTATION; MALE; POLYMORPHISM, GENETIC; POSTOPERATIVE COMPLICATIONS; RECEPTORS, CCR2; RECEPTORS, CCR5; TRANSPLANTATION;

EID: 58149101793     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/j.1365-3083.2008.02192.x     Document Type: Article

References (30)

1. Milford EL. Chronic renal allograft loss. Curr Opin Nephrol Hypertens 1994 3 : 475 9.
2. Chertow GM, Milford EL, Mackenzie HS, Brenner BM. Antigen-independent determinants of cadaveric kidney transplant failure. JAMA 1996 276 : 1732 6.
3. Horuk R. Molecular properties of the chemokines receptor family. Trends Pharmacol Sci 1994 15 : 159 65.
4. Rüster M, Sperschneider H, Fünfstück R, Stein G, Gröne HJ. Differential expression of beta-chemokines MCP-1 and RANTES and their receptors CCR1, CCR2, CCR5 in acute rejection and chronic allograft nephropathy of human renal allografts. Clin Nephrol 2004 61 : 30 9.
5. Mummidi S, Ahuja SS, McDaniel BL, Ahuja SK. The human CC chemokine receptor 5 (CCR5) gene. J Biol Chem 1997 272 : 30662 71.
6. Paterlini MG. Structure modeling of the chemokine receptor CCR5: implications for ligand binding and selectivity. Biophys J 2002 83 : 3012 31.
7. Wu L, Paxton WA, Kassam N et al. CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro. J Exp Med 1997 185 : 1681 91.
8. Liu R, Paxton WA, Choe S et al. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 Infection. Cell 1996 86 : 367 77.
9. Yoshie O, Imai T, Nomiyama H. Chemokines in immunity. Adv Immunol 2001 78 : 57 110.
10. Murphy PM, Baggiolini M, Charo IF et al. International union of pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol Rev 2000 52 : 145 76.
11. Smith MW, Dean M, Carrington M et al. Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression. Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC), ALIVE Study. Science 1997 277 : 959 65.
12. Lalor PF, Adams DH. Lymphocyte homing to allografts. Transplantation 2001 70 : 1131 9.
13. Nelson PJ, Krensky AM. Chemokines, chemokine receptors, and allograft rejection. Immunity 2001 14 : 377 86.
14. Fischereder M, Luckow B, Hocher B et al. CC chemokine receptor 5 and renal-transplant survival. Lancet 2001 357 : 1758 61.
15. Krüger B, Schröppel B, Ashkan R et al. A Monocyte chemoattractant protein-1 (MCP-1) polymorphism and outcome after renal transplantation. J Am Soc Nephrol 2002 13 : 2585 9.
16. Kang SW, Park SJ, Kim YW et al. Association of MCP-1 and CCR2 polymorphisms with the risk of late acute rejection after renal transplantation in Korean patients. Int J Immunogenet 2008 35 : 25 31.
17. Yigit B, Bozkurt N, Berber I, Titiz I, Isbir T. Analysis of CC chemokine receptor 5 and 2 polymorphisms and renal transplant survival. Cell Biochem Funct 2007 25 : 423 6.
18. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988 16 : 1215.
19. Kristiansen TB, Knudsen TB, Ohlendorff S, Eugen-Olsen J. A new multiplex PCR strategy for the simultaneous determination of four genetic polymorphisms affecting HIV-1 disease progression. J Immunol Methods 2001 252 : 147 51.
20. Michael NL, Louie LG, Rohrbaugh AL et al. The role of CCR5 and CCR2 polymorphisms in HIV-1 transmission and disease progression. Nat Med 1997 3 : 1160 4.
21. Amirzargar M, Yavangi M, Basiri A et al. Genetic association of interleukin-4, interleukin-10, and transforming growth factor-beta gene polymorphism with allograft function in renal transplant patients. Transplant Proc 2007 39 : 954 7.
22. Nikolova PN, Ivanova MI, Mihailova SM et al. Cytokine gene polymorphism in kidney transplantation - impact of TGF-beta 1,TNF-alpha and IL-6 on graft outcome. Transpl Immunol 2008 18 : 344 8.
23. Manchanda PK, Bid HK, Kumar A, Mittal RD. Genetic association of interleukin-1beta and receptor antagonist (IL-1Ra) gene polymorphism with allograft function in renal transplant patients. Transpl Immunol 2006 15 : 289 96.
24. Manchanda PK, Mittal RD. Analysis of cytokine gene polymorphisms in recipient's matched with living donors on acute rejection after renal transplantation. Mol Cell Biochem 2008 311 : 57 65.
25. Hancock WW. Chemokines and transplant immunobiology. J Am Soc Nephrol 2002 13 : 821 4.
26. Abdi R, Tran TB, Sahagun-Ruiz A et al. Chemokine receptor polymorphism and risk of acute rejection in human renal transplantation. J Am Soc Nephrol 2002 13 : 754 8.
27. Robertson H, Morley AR, Talbot D, Callanan K, Kirby JA. Renal allograft rejection: beta-chemokine involvement in the development of tubulitis. Transplantation 2000 69 : 684 7.
28. Segerer S, Cui Y, Eitner F et al. Expression of chemokines and chemokine receptors during human renal transplant rejection. Am J Kidney Dis 2001 37 : 518 31.
29. Izikson L, Klein RS, Charo IF, Weiner HL, Luster AD. Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR2). J Exp Med 2000 192 : 1075 80.
30. Fife BT, Huffnagle GB, Kuziel WA, Karpus WJ. CC. chemokine receptor 2 is critical for induction of experimental autoimmune encephalomyelitis. J Exp Med 2000 192 : 899 905.