Cytokine gene polymorphism in kidney transplantation - Impact of TGF-β1, TNF-α and IL-6 on graft outcome

Transplant Immunology

Volumn 18, Issue 4, 2008, Pages 344-348

  Nikolova, Penka N ^a   Ivanova, Milena I ^a   Mihailova, Snejina M ^a   Myhailova, Anastassia P ^a   Baltadjieva, Daniela N ^a   Simeonov, Petar L ^a   Paskalev, Emil K ^a   Naumova, Elissaveta J ^a  

^a UNIVERSITY HOSPITAL ALEXANDROVSKA   (Bulgaria)

Author keywords

Cytokine genes; Kidney transplantation; Single nucleotide polymorphism

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 6; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CHRONIC ALLOGRAFT NEPHROPATHY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA POLYMORPHISM; FEMALE; GENE EXPRESSION; GENOTYPE; HUMAN; HUMAN CELL; IMMUNOREGULATION; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM;

CHRONIC DISEASE; FEMALE; GRAFT REJECTION; GRAFT SURVIVAL; HUMANS; INTERLEUKIN-6; KIDNEY DISEASES; KIDNEY TRANSPLANTATION; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN PRECURSORS; TRANSFORMING GROWTH FACTOR BETA1; TREATMENT OUTCOME; TUMOR NECROSIS FACTOR-ALPHA;

EID: 37349075804     PISSN: 09663274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trim.2007.10.003     Document Type: Article

References (35)

1. Pascual M., Swinford R.D., Ingelfinger J.R., Williams W.W., Cosimi A.B., and Tolkoff-Rubin N. Chronic rejection and chronic cyclosporin toxicity in renal allografts. Immunol Today 19 11 (1998) 514-519
2. Zeisberg M., Strutz F., and Müller G.A. Renal fibrosis: an update. Curr Opin Nephrol Hypertens 10 3 (2001) 315-320
3. Tullius S.G., and Tilney N.L. Both alloantigen-dependent and-independent factors influence chronic allograft rejection. Transplantation 59 3 (1995) 313-318
4. Kamoun M. Cellular and molecular parameters in human renal allograft rejection. Clin Biochem 34 1 (2001) 29-34
5. Bidwell J., Keen L., Gallagher G., Kimberly R., Huizinga T., McDermott M.F., et al. Cytokine gene polymorphism in human disease: on-line databases, supplement 1. Genes Immun 2 2 (2001) 61-70
6. Hutchinson I.V., Pravica V., Perrey C., and Sinnott P. Cytokine gene polymorphisms and relevance to forms of rejection. Transplant Proc 31 1-2 (1999) 734-736
7. Pawlik A., Domanski L., Rozanski J., Florczak M., Wrzesniewska J., Dutkiewicz G., et al. The cytokine gene polymorphisms in patients with chronic kidney graft rejection. Transpl Immunol 14 1 (2005) 49-52
8. Hoffmann S., Park J., Jacobson L.M., Muehrer R.J., Lorentzen D., Kleiner D., et al. Donor genomics influence graft events: the effect of donor polymorphisms on acute rejection and chronic allograft nephropathy. Kidney Int 66 4 (2004) 1686-1693
9. Hutchinson I.V., Turner D.M., Sankaran D., Awad M.R., and Sinnott P.J. Influence of cytokine genotypes on allograft rejection. Transplant Proc 30 3 (1998) 862-863
10. Sankaran D., Asderakis A., Ashraf S., Roberts I.S., Short C.D., Dyer P.A., et al. Cytokine gene polymorphisms predict acute graft rejection following renal transplantation. Kidney Int 56 1 (1999) 281-288
11. Tinckam K., Rush D., Hutchinson I., Dembinski I., Pravica V., Jeffery J., et al. The relative importance of cytokine gene polymorphisms in the development of early and late acute rejection and six-month renal allograft pathology. Transplantation 79 7 (2005) 836-841
12. Park J.Y., Park M.H., Park H., Ha J., Kim S.J., and Ahn C. TNF-alpha and TGF-beta1 gene polymorphisms and renal allograft rejection in Koreans. Tissue Antigens 64 6 (2004) 660-666
13. Alakulppi N.S., Kyllönen L.E., Jäntti V.T., Matinlauri I.H., Partanen J., Salmela K.T., et al. C Cytokine gene polymorphisms and risks of acute rejection and delayed graft function after kidney transplantation. Transplantation 78 10 (2004) 1422-1428
14. Wramner L.G., Norrby J., Hahn-Zoric M., Ahlmén J., Börjesson P.A., and Carlström J. Impaired kidney graft survival is associated with the TNF-alpha genotype. Transplantation 78 1 (2004) 117-121
15. Muller-Steinhardt M., Hartel C., Muller B., Kirchner H., and Fricke L. The interleukin-6-174promoter polymorphism is associated with long-term kidney allograft survival. Kidney Int 62 5 (2002) 1824-1827
16. Asderakis A., Sankaran D., Dyer P., Johnson R.W., Pravica V., and Sinnott P.J. Association of polymorphisms in the human interferon-gamma and interleukin-10 gene with acute and chronic kidney transplant outcome: the cytokine effect on transplantation. Transplantation 71 5 (2001) 674-677
17. Inigo P., Lario S., Campistol J.M., Bescos M., Campos B., and Oppenheimer F. Role of transforming growth factor beta-1 gene polymorphisms in the development of chronic allograft nephropathy in renal transplant recipients. Nefrologia 23 4 (2003) 312-320
18. Morris-Stiff G. TGFbeta-1 and the development of chronic graft nephropathy: relative roles of gene, mRNA and protein. Ann R Coll Surg Engl 87 5 (2005) 326-330
19. Miller S.A., Dykes D.D., and Polesky H.F. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16 3 (1988) 1215
20. Kroeger K.M., Steer J.H., Joyce D.A., and Abraham L.J. Effects of stimulus and cell type on the expression of the-308 tumour necrosis factor promoter polymorphism. Cytokine 12 2 (2000) 110-119
21. Huang DR, Pirskanen R, Matell G, Lefvert AK. Tumour necrosis factor-alpha polymorphism and secretion in myasthenia gravis. J Neuroimmunol 1999; 94(1-2):165-71.
22. Awad M.R., El-Gamel A., Hasleton P., Turner D.M., Sinnott P.J., and Hutchinson I.V. Genotypic variation in the transforming growth factor-beta1 gene: association with transforming growth factor-beta1 production, fibrotic lung disease, and graft fibrosis after lung transplantation. Transplantation 66 8 (1998) 1014-1020
23. Crawley E., Kay R., Sillibourne J., Patel P., Hutchinson I., and Woo P. Polymorphic haplotypes of the interleukin-10 5′ flanking region determine variable interleukin-10 transcription and are associated with particular phenotypes of juvenile rheumatoid arthritis. Arthritis Rheum 42 6 (1999) 1101-1108
24. Mäurer M., Kruse N., Giess R., Toyka K.V., and Rieckmann P. Genetic variation at position-1082 of the interleukin 10 (IL10) promotor and the outcome of multiple sclerosis. J Neuroimmunol 104 1 (2000) 98-100
25. Fishman D., Faulds G., Jeffery R., Mohamed-Ali V., Yudkin J.S., Humphries S., et al. The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Invest 102 7 (1998) 1369-1376
26. Pravica V., Perrey C., Stevens A., Lee J.H., and Hutchinson I.V. A single nucleotide polymorphism in the first intron of the human IFN-gamma gene: absolute correlation with a polymorphic CA microsatellite marker of high IFN-gamma production. Hum Immunol 61 9 (2000) 863-866
27. Yilmaz S., Paavonen T., and Hayry P. Chronic rejection of rat renal allografts. II. The impact of prolonged ischemia time on transplant histology. Transplantation 53 4 (1992) 823-827
28. Hutchinson I.V. Cardiac allograft vasculopathy-the cellular attack. Z Kardiol 89 Suppl 9 (2000) [IX/16-20]
29. Suthanthiran M. The importance of genetic polymorphisms in renal transplantation. Curr Opin Urol 10 2 (2000) 71-75
30. Perrey C., Pravica V., Sinnott P.J., and Hutchinson I.V. Genotyping for polymorphisms in interferon-gamma, interleukin-10, transforming growth factor-beta 1 and tumour necrosis factor-alpha genes: a technical report. Transpl Immunol 6 3 (1998) 193-197
31. Wilson A.G., Symons J.A., McDowell T.L., McDevitt H.O., and Duff G.W. Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc Natl Acad Sci U S A 94 7 (1997) 3195-3199
32. Lee H., Clark B., Gooi H.C., Stoves J., and Newstead C.G. Influence of recipient and donor IL-1alpha, IL-4, and TNFalpha genotypes on the incidence of acute renal allograft rejection. J Clin Pathol 57 1 (2004) 101-103
33. Hoffmann S.C., Stanley E.M., Darrin Cox E., Craighead N., DiMercurio B.S., and Koziol D.E. Association of cytokine polymorphic inheritance and in vitro cytokine production in anti-CD3/CD28-stimulated peripheral blood lymphocytes. Transplantation 72 8 (2001) 1444-1450
34. Chow K.M., Szeto C.C., Poon P., Lau W.Y., Lai F.M., and Li P.K. Transforming growth factor-beta1 gene polymorphism in renal transplant recipients. Ren Fail 27 6 (2005) 671-675
35. Ochsner S., Guo Z., Binswanger U., and Knoflach A. TGF-beta 1 gene expression in stable renal transplant recipients: influence of TGF-beta 1 gene polymorphism and immunosuppression. Transplant Proc 34 7 (2002) 2901-2903