Interactions of antiviral indolo[2,3-b]quinoxaline derivatives with DNA

Journal of Medicinal Chemistry

Volumn 51, Issue 24, 2008, Pages 7744-7750

  Wilhelmsson, L Marcus ^a   Kingi, Ngarita ^b,c   Bergman, Jan ^b  

^a CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c VIRONOVA AB   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

2,3 DIMETHYL 6 (2 DIMETHYLAMINOETHYL) 6H INDOLO[2,3 B]QUINOXALINE; 2,3 DIMETHYL 6 [2 (TRIMETHYLAMINO)ETHYL] 6H INDOLO[2,3 B]QUINOXALINE IODIDE; 9 AMINO 2,3 DIMETHYL 6 (2 DIMETHYLAMINOETHYL) 6H INDOLO[2,3 B]QUINOXALINE; ANTIVIRUS AGENT; BISINDOLO[2,3 B]QUINOXALINE 6H (3,3:10,10 TETRAMETHYL) 3,10 DI(3,10)AZADODECANE BROMIDE; BISINDOLO[2,3 B]QUINOXALINE 6H (3,3:7,7 TETRAMETHYL) 3,10 DI(3,7)AZAHEPTANE BROMIDE; INDOLO[2,3 B]QUINOXALINE DERIVATIVE; NUCLEIC ACID BASE; UNCLASSIFIED DRUG;

ABSORPTION SPECTROSCOPY; ANTIVIRAL ACTIVITY; ARTICLE; BINDING AFFINITY; COMPETITIVE INHIBITION; CYTOMEGALOVIRUS; DRUG DNA BINDING; DRUG DNA INTERACTION; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; FLUORESCENCE SPECTROSCOPY; HERPES SIMPLEX VIRUS 1; INTERCALATION COMPLEX; LINEAR DICHROISM; NONHUMAN; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; VARICELLA ZOSTER VIRUS;

ANIMALS; ANTIVIRAL AGENTS; CATTLE; CHEMISTRY, PHARMACEUTICAL; CYTOMEGALOVIRUS; DIMERIZATION; DNA; DRUG DESIGN; HERPESVIRUS 1, HUMAN; HERPESVIRUS 3, HUMAN; HUMANS; MODELS, CHEMICAL; QUINOXALINES; SPECTROMETRY, FLUORESCENCE;

EID: 58149088309     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm800787b     Document Type: Article

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