Solution structure and dynamics of a complex between dna and the antitumor bisnaphthalimide LU-79553: Intercalated ring flipping on the millisecond time scale

Biochemistry

Volumn 38, Issue 46, 1999, Pages 15104-15115

  Gallego, José ^a   Reid, Brian R ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BISNAPHTHALIMIDE; DNA; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; DNA DRUG COMPLEX; DRUG STRUCTURE; ENERGY; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS;

AMIDES; ANTINEOPLASTIC AGENTS; BASE SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DNA; HUMANS; INTERCALATING AGENTS; ISOQUINOLINES; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEIC ACID HETERODUPLEXES; OLIGONUCLEOTIDES; PROTEIN CONFORMATION; SOLUTIONS; THERMODYNAMICS;

EID: 0033576252     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9915869     Document Type: Article

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