A surprising mechanistic "switch" in Lewis acid activation: A bifunctional, asymmetric approach to α-hydroxy acid derivatives

Journal of the American Chemical Society

Volumn 130, Issue 50, 2008, Pages 17085-17094

  Abraham, Ciby J ^a   Paull, Daniel H ^a   Bekele, Tefsit ^a,c   Scerba, Michael T ^a   Dudding, Travis ^b   Lectka, Thomas ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b BROCK UNIVERSITY   (Canada)

^c AMRI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIFUNCTIONAL; BINDING MOTIFS; CARBONYL DERIVATIVES; CINCHONA ALKALOIDS; ENOLATE; ENOLATES; EXCELLENT YIELDS; HIGH YIELDS; HYDROXY ACIDS; LEWIS ACIDS; MECHANISTIC STUDIES; NMR SPECTROSCOPIES; OPENING REACTIONS; RATE OF REACTIONS;

CARBOXYLIC ACIDS; COORDINATION REACTIONS; ENANTIOSELECTIVITY; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ACIDS;

ACIDS; CATALYSIS; CHLORANIL; HYDROXY ACIDS; MODELS, ANATOMIC; MOLECULAR STRUCTURE; PALLADIUM; PHOSPHITES; SPECTROPHOTOMETRY; STEREOISOMERISM;

EID: 58049221126     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja806818a     Document Type: Article

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