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Volumn 107, Issue 1, 2009, Pages 194-205

Chromosomal mosaicism in mouse two-cell embryos after paternal exposure to acrylamide

Author keywords

Acrylamide; Fluorescence in situ hybridization; In vivo; Spermatogenesis

Indexed keywords

ACRYLAMIDE;

EID: 58049200679     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfn209     Document Type: Article
Times cited : (13)

References (69)
  • 1
    • 85069244887 scopus 로고    scopus 로고
    • Adler, I. D. (1990). Clastogenic effects of acrylamide in different germ-cell stages of male mice. In Banbury Report 34: Biology of Mammalian Germ Cell Mutagenesis (J. W. Allen, B. A. Bridges, M. F. Lyon, M. J. Moses, and L. B. Russell, Eds.), pp. 115-131. Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
    • Adler, I. D. (1990). Clastogenic effects of acrylamide in different germ-cell stages of male mice. In Banbury Report 34: Biology of Mammalian Germ Cell Mutagenesis (J. W. Allen, B. A. Bridges, M. F. Lyon, M. J. Moses, and L. B. Russell, Eds.), pp. 115-131. Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
  • 2
    • 0028124396 scopus 로고
    • Dose response for heritable translocations induced by acrylamide in spermatids of mice
    • Adler, I. D., Reitmeir, P., Schmoller, R., and Schriever-Schwemmer, G. (1994). Dose response for heritable translocations induced by acrylamide in spermatids of mice. Mutat. Res. 309, 285-291.
    • (1994) Mutat. Res , vol.309 , pp. 285-291
    • Adler, I.D.1    Reitmeir, P.2    Schmoller, R.3    Schriever-Schwemmer, G.4
  • 3
    • 0027447719 scopus 로고
    • Mitotic errors in somatic cells cause trisomy 21 in about 4.5% of cases and are not associated with maternal age
    • Antonarakis, S. E., Avramopoulos, D., Blouin, J.-L., Conover Talbot, C., Jr., and Schinzel, A. A. (1993). Mitotic errors in somatic cells cause trisomy 21 in about 4.5% of cases and are not associated with maternal age. Nat. Genet. 3, 146-149.
    • (1993) Nat. Genet , vol.3 , pp. 146-149
    • Antonarakis, S.E.1    Avramopoulos, D.2    Blouin, J.-L.3    Conover Talbot Jr., C.4    Schinzel, A.A.5
  • 5
    • 0035004121 scopus 로고    scopus 로고
    • Time-course of translocation and dicentric frequencies in a radiation accident case
    • Bauchinger, M., Schmid, E., and Braselmann, H. (2001). Time-course of translocation and dicentric frequencies in a radiation accident case. Int. J. Radiat. Biol. 77, 553-557.
    • (2001) Int. J. Radiat. Biol , vol.77 , pp. 553-557
    • Bauchinger, M.1    Schmid, E.2    Braselmann, H.3
  • 6
    • 0035871148 scopus 로고    scopus 로고
    • Analysis of a malsegregating mouse Y chromosome: Evidence that the earliest cleavage divisions of the mammalian embryo are non-disjunction-prone
    • Bean, C. J., Hunt, P. A., Millie, E. A., and Hassold, T. J. (2001). Analysis of a malsegregating mouse Y chromosome: Evidence that the earliest cleavage divisions of the mammalian embryo are non-disjunction-prone. Hum. Mol. Genet. 10, 963-972.
    • (2001) Hum. Mol. Genet , vol.10 , pp. 963-972
    • Bean, C.J.1    Hunt, P.A.2    Millie, E.A.3    Hassold, T.J.4
  • 7
    • 0036180155 scopus 로고    scopus 로고
    • Chromosomal mosaicism throughout human preimplantation development in vitro: Incidence, type, and relevance to embryo outcome
    • Bielanska, M., Tan, S. L., and Ao, A. (2002a). Chromosomal mosaicism throughout human preimplantation development in vitro: Incidence, type, and relevance to embryo outcome. Hum. Reprod. 17, 413-419.
    • (2002) Hum. Reprod , vol.17 , pp. 413-419
    • Bielanska, M.1    Tan, S.L.2    Ao, A.3
  • 8
    • 0036097223 scopus 로고    scopus 로고
    • Different probe combinations for assessment of postzygotic chromosomal imbalances in human embryos
    • Bielanska, M., Tan, S. L., and Ao, A. (2002b). Different probe combinations for assessment of postzygotic chromosomal imbalances in human embryos. J. Assist. Reprod. Genet. 19, 177-182.
    • (2002) J. Assist. Reprod. Genet , vol.19 , pp. 177-182
    • Bielanska, M.1    Tan, S.L.2    Ao, A.3
  • 9
    • 0030998545 scopus 로고    scopus 로고
    • Apoptosis during mouse blastocyst formation: Evidence for a role for survival factors including transforming growth factor alpha
    • Brison, D. R., and Schultz, R. M. (1997). Apoptosis during mouse blastocyst formation: Evidence for a role for survival factors including transforming growth factor alpha. Biol. Reprod. 56, 1088-1096.
    • (1997) Biol. Reprod , vol.56 , pp. 1088-1096
    • Brison, D.R.1    Schultz, R.M.2
  • 10
    • 0015592845 scopus 로고
    • Chromosome aberrations and radiation-induced cell death. I. Transmission and survival parameters of aberrations
    • Carrano, A. V. (1973a). Chromosome aberrations and radiation-induced cell death. I. Transmission and survival parameters of aberrations. Mutat. Res. 17, 341-353.
    • (1973) Mutat. Res , vol.17 , pp. 341-353
    • Carrano, A.V.1
  • 11
    • 0015589438 scopus 로고
    • Chromosome aberrations and radiation-induced cell death. II. Predicted and observed cell survival
    • Carrano, A. V. (1973b). Chromosome aberrations and radiation-induced cell death. II. Predicted and observed cell survival. Mutat. Res. 17, 355-366.
    • (1973) Mutat. Res , vol.17 , pp. 355-366
    • Carrano, A.V.1
  • 12
    • 0029123223 scopus 로고
    • Acrylamide: A review of its genotoxicity and an assessment of heritable genetic risk
    • Dearfield, K. L., Douglas, G. R., Ehling, U. H., Moore, M. M., Sega, G. A., and Brusick, D. J. (1995). Acrylamide: A review of its genotoxicity and an assessment of heritable genetic risk. Mutat. Res. 330 71-99.
    • (1995) Mutat. Res , vol.330 , pp. 71-99
    • Dearfield, K.L.1    Douglas, G.R.2    Ehling, U.H.3    Moore, M.M.4    Sega, G.A.5    Brusick, D.J.6
  • 13
    • 0031009264 scopus 로고    scopus 로고
    • Multicolour FISH detects frequent chromosomal mosaicism and chaotic division in normal preimplantation embryos from fertile patients
    • Delhanty, J. D. A., Harper, J. C., Ao, A., Handyside, A. H., and Winston, R. M. (1997). Multicolour FISH detects frequent chromosomal mosaicism and chaotic division in normal preimplantation embryos from fertile patients. Hum. Genet. 99, 755-760.
    • (1997) Hum. Genet , vol.99 , pp. 755-760
    • Delhanty, J.D.A.1    Harper, J.C.2    Ao, A.3    Handyside, A.H.4    Winston, R.M.5
  • 14
    • 0026675632 scopus 로고
    • Reevaluation of the induction of specific-locus mutations in spermatogonia of the mouse by acrylamide
    • Ehling, U. H., and Neuhauser-Klaus, A. (1992). Reevaluation of the induction of specific-locus mutations in spermatogonia of the mouse by acrylamide. Mutat. Res. 293, 185-191.
    • (1992) Mutat. Res , vol.293 , pp. 185-191
    • Ehling, U.H.1    Neuhauser-Klaus, A.2
  • 15
    • 12244299194 scopus 로고    scopus 로고
    • Higher degree of chromosome mosaicism in preimplantation embryos from carriers of Robertsonian translocation t(13;14) in comparison with embryos from karyotypically normal IVF patients
    • Emiliani, S., Gonzalez-Merino, E., Van den Bergh, M., Abramowicz, M., and Englert, Y. (2003). Higher degree of chromosome mosaicism in preimplantation embryos from carriers of Robertsonian translocation t(13;14) in comparison with embryos from karyotypically normal IVF patients. J. Assist. Reprod. Genet. 20, 95-100.
    • (2003) J. Assist. Reprod. Genet , vol.20 , pp. 95-100
    • Emiliani, S.1    Gonzalez-Merino, E.2    Van den Bergh, M.3    Abramowicz, M.4    Englert, Y.5
  • 16
    • 0029867096 scopus 로고    scopus 로고
    • Induction of hypoploidy and cell cycle delay by acrylamide in somatic and germinal cells of male mice
    • Gassner, P., and Adler, I. D. (1996). Induction of hypoploidy and cell cycle delay by acrylamide in somatic and germinal cells of male mice. Mutat. Res. 367, 195-202.
    • (1996) Mutat. Res , vol.367 , pp. 195-202
    • Gassner, P.1    Adler, I.D.2
  • 18
  • 19
    • 0035852698 scopus 로고    scopus 로고
    • From cell death to embryo arrest: Mathematical models of human preimplantation embryo development
    • Hardy, K., Spanos, S., Becker, D., Iannelli, P., Winston, R. M., and Stark, J. (2001). From cell death to embryo arrest: Mathematical models of human preimplantation embryo development. Proc. Natl. Acad. Sci. U. S. A. 98, 1655-1660.
    • (2001) Proc. Natl. Acad. Sci. U. S. A , vol.98 , pp. 1655-1660
    • Hardy, K.1    Spanos, S.2    Becker, D.3    Iannelli, P.4    Winston, R.M.5    Stark, J.6
  • 21
    • 0002232454 scopus 로고
    • Prenatal diagnosis of chromosomal abnormalities through amniocentesis
    • A. Milunsky, Ed, pp, The John Hopkins University Press, Baltimore and London
    • Hsu, L. Y. F. (1992). Prenatal diagnosis of chromosomal abnormalities through amniocentesis. In Genetic Disorders and the Fetus (A. Milunsky, Ed.), pp. 155-210. The John Hopkins University Press, Baltimore and London.
    • (1992) Genetic Disorders and the Fetus , pp. 155-210
    • Hsu, L.Y.F.1
  • 24
    • 0034049607 scopus 로고    scopus 로고
    • Pathogenesis of chromosomal mosaicism and its effects on early human development
    • Kalousek, D. K. (2000). Pathogenesis of chromosomal mosaicism and its effects on early human development. Am. J. Hum. Genet. 91, 39-45.
    • (2000) Am. J. Hum. Genet , vol.91 , pp. 39-45
    • Kalousek, D.K.1
  • 25
    • 0025991931 scopus 로고
    • Confirmation of CVS mosaicism in term placentae and high frequency of intrauterine growth retardation association with confined placental mosaicism
    • Kalousek, D. K., Howard-Peebles, P. N., Olson, S. B., Barrett, I. J., Dorfman, A., Black, S. H., Schulman, J. D., and Wilson, R. D. (1991). Confirmation of CVS mosaicism in term placentae and high frequency of intrauterine growth retardation association with confined placental mosaicism. Prenat. Diagn. 11, 743-750.
    • (1991) Prenat. Diagn , vol.11 , pp. 743-750
    • Kalousek, D.K.1    Howard-Peebles, P.N.2    Olson, S.B.3    Barrett, I.J.4    Dorfman, A.5    Black, S.H.6    Schulman, J.D.7    Wilson, R.D.8
  • 26
    • 0030055570 scopus 로고    scopus 로고
    • Confined placental mosaicism
    • Kalousek, D. K., and Vekemans, M. (1996). Confined placental mosaicism. J. Med. Genet. 33, 529-533.
    • (1996) J. Med. Genet , vol.33 , pp. 529-533
    • Kalousek, D.K.1    Vekemans, M.2
  • 27
    • 1042280229 scopus 로고    scopus 로고
    • Mitotic errors in chromosome 21 of human preimplantation embryos are associated with non-viability
    • Katz-Jaffe, M. G., Trounson, A. O., and Cram, D. S. (2004). Mitotic errors in chromosome 21 of human preimplantation embryos are associated with non-viability. Mol. Hum. Reprod. 10, 143-147.
    • (2004) Mol. Hum. Reprod , vol.10 , pp. 143-147
    • Katz-Jaffe, M.G.1    Trounson, A.O.2    Cram, D.S.3
  • 28
    • 24944433962 scopus 로고    scopus 로고
    • Chromosome 21 mosaic human preimplantation embryos predominantly arise from diploid conceptions
    • Katz-Jaffe, M. G., Trounson, A. O., and Cram, D. S. (2005). Chromosome 21 mosaic human preimplantation embryos predominantly arise from diploid conceptions. Fertil. Steril. 84, 634-643.
    • (2005) Fertil. Steril , vol.84 , pp. 634-643
    • Katz-Jaffe, M.G.1    Trounson, A.O.2    Cram, D.S.3
  • 29
    • 0036859988 scopus 로고    scopus 로고
    • Sex-specific differences in meiotic chromosome segregation revealed by dicentric bridge resolution in mice
    • Koehler, K. E., Millie, E. A., Cherry, J. P., Burgoyne, P. S., Evans, E. P., Hunt, P. A., and Hassold, T. J. (2002). Sex-specific differences in meiotic chromosome segregation revealed by dicentric bridge resolution in mice. Genetics 162, 1367-1379.
    • (2002) Genetics , vol.162 , pp. 1367-1379
    • Koehler, K.E.1    Millie, E.A.2    Cherry, J.P.3    Burgoyne, P.S.4    Evans, E.P.5    Hunt, P.A.6    Hassold, T.J.7
  • 30
    • 0023652384 scopus 로고
    • A genetic analysis of dicentric minichromosomes in Saccharomyces cerevisiae
    • Koshland, D., Rutledge, L., Fitzgerald-Hayes, M., and Hartwell, L. H. (1987). A genetic analysis of dicentric minichromosomes in Saccharomyces cerevisiae. Cell 48, 801-812.
    • (1987) Cell , vol.48 , pp. 801-812
    • Koshland, D.1    Rutledge, L.2    Fitzgerald-Hayes, M.3    Hartwell, L.H.4
  • 31
    • 0034608277 scopus 로고    scopus 로고
    • Comparative genomic hybridization: A new approach to screening for intrauterine complete or mosaic aneuploidy
    • Lestou, V. S., Desilets, V., Lomax, B. L., Barrett, I. J., Wilson, R. D., Langlois, S., and Kalousek, D. K. (2000). Comparative genomic hybridization: A new approach to screening for intrauterine complete or mosaic aneuploidy. Am. J. Hum. Genet. 92, 281-284.
    • (2000) Am. J. Hum. Genet , vol.92 , pp. 281-284
    • Lestou, V.S.1    Desilets, V.2    Lomax, B.L.3    Barrett, I.J.4    Wilson, R.D.5    Langlois, S.6    Kalousek, D.K.7
  • 32
    • 30044452115 scopus 로고    scopus 로고
    • The fate of mosaic aneuploid embryos during mouse development
    • Lightfoot, D. A., Kouznetsova, A., Mahdy, E., Wilbertz, J., and Hoog, C. (2006). The fate of mosaic aneuploid embryos during mouse development. Dev. Biol. 289, 384-394.
    • (2006) Dev. Biol , vol.289 , pp. 384-394
    • Lightfoot, D.A.1    Kouznetsova, A.2    Mahdy, E.3    Wilbertz, J.4    Hoog, C.5
  • 33
    • 0029027635 scopus 로고
    • Chromatid and chromosome type breakage-fusion-bridge cycles in wheat (Triticum aestivum L.)
    • Lukaszewski, A. J. (1995). Chromatid and chromosome type breakage-fusion-bridge cycles in wheat (Triticum aestivum L.). Genetics 140, 1069-1085.
    • (1995) Genetics , vol.140 , pp. 1069-1085
    • Lukaszewski, A.J.1
  • 34
    • 0023417634 scopus 로고
    • Cytogenetic technique for mouse metaphase II oocytes
    • Mailhes, J. B., and Yuan, Z. P. (1987). Cytogenetic technique for mouse metaphase II oocytes. Gamete Res. 18, 77-83.
    • (1987) Gamete Res , vol.18 , pp. 77-83
    • Mailhes, J.B.1    Yuan, Z.P.2
  • 36
    • 1242298822 scopus 로고    scopus 로고
    • Paternally transmitted chromosomal aberrations in mouse zygotes determine their embryonic fate
    • Marchetti, F., Bishop, J. B., Cosentino, L., Moore, D., II., and Wyrobek, A. J. (2004). Paternally transmitted chromosomal aberrations in mouse zygotes determine their embryonic fate. Biol. Reprod. 70 616-624.
    • (2004) Biol. Reprod , vol.70 , pp. 616-624
    • Marchetti, F.1    Bishop, J.B.2    Cosentino, L.3    Moore II, D.4    Wyrobek, A.J.5
  • 38
    • 36749078665 scopus 로고    scopus 로고
    • Disruption of maternal DNA repair increases sperm-derived chromosomal aberrations
    • Marchetti, F., Essers, J., Kanaar, R., and Wyrobek, A. J. (2007). Disruption of maternal DNA repair increases sperm-derived chromosomal aberrations. Proc. Natl. Acad. Sci. U. S. A. 1049 17725-17729.
    • (2007) Proc. Natl. Acad. Sci. U. S. A , vol.1049 , pp. 17725-17729
    • Marchetti, F.1    Essers, J.2    Kanaar, R.3    Wyrobek, A.J.4
  • 39
    • 0031431342 scopus 로고    scopus 로고
    • Induction of chromosomal aberrations in mouse zygotes by acrylamide treatment of male germ cells and their correlation with dominant lethality and heritable translocations
    • Marchetti, F., Lowe, X., Bishop, J., and Wyrobek, J. (1997). Induction of chromosomal aberrations in mouse zygotes by acrylamide treatment of male germ cells and their correlation with dominant lethality and heritable translocations. Environ. Mol. Mutagen. 30, 410-417.
    • (1997) Environ. Mol. Mutagen , vol.30 , pp. 410-417
    • Marchetti, F.1    Lowe, X.2    Bishop, J.3    Wyrobek, J.4
  • 40
    • 0030473631 scopus 로고    scopus 로고
    • Paternally inherited chromosomal structural aberrations detected in mouse first-cleavage zygote metaphases by multicolor fluorescence in situ hybridization painting
    • Marchetti, F., Lowe, X., Moore, D. I., Bishop, J., and Wyrobek, A. J. (1996). Paternally inherited chromosomal structural aberrations detected in mouse first-cleavage zygote metaphases by multicolor fluorescence in situ hybridization painting. Chromosome Res. 4, 604-613.
    • (1996) Chromosome Res , vol.4 , pp. 604-613
    • Marchetti, F.1    Lowe, X.2    Moore, D.I.3    Bishop, J.4    Wyrobek, A.J.5
  • 41
    • 23844495086 scopus 로고    scopus 로고
    • Mechanisms and consequences of paternally-transmitted chromosomal abnormalities, Birth Defects Res
    • Marchetti, F., and Wyrobek, A. J. (2005). Mechanisms and consequences of paternally-transmitted chromosomal abnormalities, Birth Defects Res. C Embryo Today 75, 112-129.
    • (2005) C Embryo Today , vol.75 , pp. 112-129
    • Marchetti, F.1    Wyrobek, A.J.2
  • 42
    • 40649108031 scopus 로고    scopus 로고
    • DNA repair decline during mouse spermiogenesis results in the accumulation of heritable DNA damage
    • Epub February 20
    • Marchetti, F., and Wyrobek, A. J. (2008). DNA repair decline during mouse spermiogenesis results in the accumulation of heritable DNA damage. DNA Repair 7, 572-581; Epub February 20, 2008.
    • (2008) DNA Repair , vol.7 , pp. 572-581
    • Marchetti, F.1    Wyrobek, A.J.2
  • 43
    • 0018198093 scopus 로고
    • Manufactured hexaparental mice show that adults are derived for three embryonic cells
    • Markert, C. L., and Petters, R. M. (1978). Manufactured hexaparental mice show that adults are derived for three embryonic cells. Science 202, 56-58.
    • (1978) Science , vol.202 , pp. 56-58
    • Markert, C.L.1    Petters, R.M.2
  • 44
    • 78651149795 scopus 로고
    • The fertilizable life of ova and their morphology following delayed insemination in mature and immature mice
    • Marsiton, J. H., and Chang, M. C. (1964). The fertilizable life of ova and their morphology following delayed insemination in mature and immature mice. J. Exp. Zool. 155, 237-251.
    • (1964) J. Exp. Zool , vol.155 , pp. 237-251
    • Marsiton, J.H.1    Chang, M.C.2
  • 45
    • 0000075523 scopus 로고
    • The behavior in successive nuclear divisions of a chromosome broken at meiosis
    • McClintock, B. (1939). The behavior in successive nuclear divisions of a chromosome broken at meiosis. Proc. Natl. Acad. Sci. U. S. A. 25, 405-416.
    • (1939) Proc. Natl. Acad. Sci. U. S. A , vol.25 , pp. 405-416
    • McClintock, B.1
  • 47
    • 0037015489 scopus 로고    scopus 로고
    • Acrylamide is formed in the Maillard reaction
    • Mottram, D. S., Wedzicha, B. L., and Dodson, A. T. (2002). Acrylamide is formed in the Maillard reaction. Nature 419, 448-449.
    • (2002) Nature , vol.419 , pp. 448-449
    • Mottram, D.S.1    Wedzicha, B.L.2    Dodson, A.T.3
  • 48
    • 0032079998 scopus 로고    scopus 로고
    • Chromosome abnormalities in embryos obtained after conventional in vitro fertilization and intracytoplasmic sperm injection
    • Munné, S., Márquez, C., Reing, A., Garrisi, J., and Alikani, M. (1998). Chromosome abnormalities in embryos obtained after conventional in vitro fertilization and intracytoplasmic sperm injection. Fertil. Steril. 69, 904-908.
    • (1998) Fertil. Steril , vol.69 , pp. 904-908
    • Munné, S.1    Márquez, C.2    Reing, A.3    Garrisi, J.4    Alikani, M.5
  • 51
    • 0028145916 scopus 로고
    • Acrylamide-induced chromosomal damage in male mouse germ cells detected by cytogenetic analysis of one-cell zygotes
    • Pacchierotti, F., Tiveron, C., D'Archivio, M., Bassani, B., Cordelli, E., Leter, G., and Spanò, M. (1994). Acrylamide-induced chromosomal damage in male mouse germ cells detected by cytogenetic analysis of one-cell zygotes. Mutat. Res. 309, 273-284.
    • (1994) Mutat. Res , vol.309 , pp. 273-284
    • Pacchierotti, F.1    Tiveron, C.2    D'Archivio, M.3    Bassani, B.4    Cordelli, E.5    Leter, G.6    Spanò, M.7
  • 52
    • 0028854976 scopus 로고
    • Molecular studies of chromosomal mosaicism: Relative frequency of chromosome gain or loss and possible role of cell selection
    • Robinson, W. P., Binkert, F., Bernasconi, F., Lorda-Sanchez, I., Werder, E. A., and Schinzel, A. A. (1995). Molecular studies of chromosomal mosaicism: Relative frequency of chromosome gain or loss and possible role of cell selection. Am. J. Hum. Genet. 56, 444-451.
    • (1995) Am. J. Hum. Genet , vol.56 , pp. 444-451
    • Robinson, W.P.1    Binkert, F.2    Bernasconi, F.3    Lorda-Sanchez, I.4    Werder, E.A.5    Schinzel, A.A.6
  • 53
    • 0036326280 scopus 로고    scopus 로고
    • Analysis of acrylamide in cooked foods by liquid chromatography tandem mass spectrometry
    • Rosen, J., and Hellenas, K. E. (2002). Analysis of acrylamide in cooked foods by liquid chromatography tandem mass spectrometry. Analyst 127, 880-882.
    • (2002) Analyst , vol.127 , pp. 880-882
    • Rosen, J.1    Hellenas, K.E.2
  • 54
    • 0026099950 scopus 로고
    • Induction of specific-locus mutations in male germ cells of the mouse by acrylamide monomer
    • Russell, L. B., Hunsicker, P. R., Cacheiro, N. L., and Generoso, W. M. (1991). Induction of specific-locus mutations in male germ cells of the mouse by acrylamide monomer. Mutat. Res. 262, 101-107.
    • (1991) Mutat. Res , vol.262 , pp. 101-107
    • Russell, L.B.1    Hunsicker, P.R.2    Cacheiro, N.L.3    Generoso, W.M.4
  • 55
    • 0016360646 scopus 로고
    • Unscheduled DNA synthesis in the germ cells of male mice exposed in vivo to the chemical mutagen ethyl methanesulphonate
    • Sega, G. A. (1974). Unscheduled DNA synthesis in the germ cells of male mice exposed in vivo to the chemical mutagen ethyl methanesulphonate. Proc. Natl. Acad. Sci. U. S. A. 71, 4955-4950.
    • (1974) Proc. Natl. Acad. Sci. U. S. A , vol.71 , pp. 4955-4950
    • Sega, G.A.1
  • 56
    • 18844470809 scopus 로고
    • Unscheduled DNA synthesis (DNA repair) in the germ cells of male mice: Its role in the study of mammalian mutagenesis
    • Sega, G. A. (1979). Unscheduled DNA synthesis (DNA repair) in the germ cells of male mice: Its role in the study of mammalian mutagenesis. Genetics 92, s49-s58.
    • (1979) Genetics , vol.92
    • Sega, G.A.1
  • 57
    • 0024343913 scopus 로고
    • Acrylamide binding to the DNA and protamine of spermiogenic stages of the mouse and its relationship to genetic damage
    • Sega, G. A., Valdivia Alcota, R. P., Tancongeo, C. P., and Brimer, P. (1989). Acrylamide binding to the DNA and protamine of spermiogenic stages of the mouse and its relationship to genetic damage. Murat. Res. 216, 221-230.
    • (1989) Murat. Res , vol.216 , pp. 221-230
    • Sega, G.A.1    Valdivia Alcota, R.P.2    Tancongeo, C.P.3    Brimer, P.4
  • 61
    • 0034536141 scopus 로고    scopus 로고
    • Unscheduled DNA synthesis assay in mammalian spermatogenic cells: An update
    • Sotomayor, R. E., and Sega, G. A. (2000). Unscheduled DNA synthesis assay in mammalian spermatogenic cells: An update. Environ. Mol. Mutagen. 36, 255-265.
    • (2000) Environ. Mol. Mutagen , vol.36 , pp. 255-265
    • Sotomayor, R.E.1    Sega, G.A.2
  • 64
    • 0031921666 scopus 로고    scopus 로고
    • Micronuclei and developmental abnormalities in 4-day mouse embryos after paternal treatment with acrylamide
    • Titenko-Holland, N., Ahlborn, T., Lowe, X., Shang, N., Smith, M. T., and Wyrobek, A. J. (1998). Micronuclei and developmental abnormalities in 4-day mouse embryos after paternal treatment with acrylamide. Environ. Mol. Mutagen. 31, 206-217.
    • (1998) Environ. Mol. Mutagen , vol.31 , pp. 206-217
    • Titenko-Holland, N.1    Ahlborn, T.2    Lowe, X.3    Shang, N.4    Smith, M.T.5    Wyrobek, A.J.6
  • 65
    • 17044414564 scopus 로고    scopus 로고
    • Persistence of chromosome aberrations following acute radiation: I, PAINT translocations, dicentrics, rings, fragments, and insertions
    • Tucker, J. D., Cofield, J., Matsumoto, K., Ramsey. M. J., and Freeman, D. C. (2005). Persistence of chromosome aberrations following acute radiation: I, PAINT translocations, dicentrics, rings, fragments, and insertions. Environ. Mol. Mutagen. 45, 229-248.
    • (2005) Environ. Mol. Mutagen , vol.45 , pp. 229-248
    • Tucker, J.D.1    Cofield, J.2    Matsumoto, K.3    Ramsey, M.J.4    Freeman, D.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.