Tyrosines of human and mouse transferrin covalently labeled by organophosphorus agents: A new motif for binding to proteins that have no active site serine

Toxicological Sciences

Volumn 107, Issue 1, 2009, Pages 144-155

  Li, Bin ^a   Schopfer, Lawrence M ^a   Grigoryan, Hasmik ^a   Thompson, Charles M ^b   Hinrichs, Steven H ^c   Masson, Patrick ^d   Lockridge, Oksana ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF MONTANA   (United States)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^d CENTRE DE RECHERCHES   (France)

Author keywords

Mass spectrometry; Plasma; Sarin; Soman; Transferrin; Tyrosine residue

Indexed keywords

ALBUMIN; ARGINYLTYROSYLTHREONYLARGININE; CHLORPYRIFOS; DICHLORVOS; DYFLOS; ORGANOPHOSPHORUS COMPOUND; SARIN; SERINE; SOMAN; SYNTHETIC PEPTIDE; TRANSFERRIN; TUBULIN; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL LABELING; CHEMICAL STRUCTURE; CONTROLLED STUDY; COVALENT BOND; HUMAN; IN VITRO STUDY; MASS SPECTROMETER; MASS SPECTROMETRY; MOUSE; NONHUMAN; PEPTIDE ANALYSIS; PH; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN MODIFICATION; PROTEIN MOTIF; STRUCTURE ANALYSIS;

ANIMALS; BINDING SITES; BIOTIN; BLOTTING, WESTERN; HUMANS; MICE; MODELS, CHEMICAL; ORGANOPHOSPHORUS COMPOUNDS; SOMAN; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TANDEM MASS SPECTROMETRY; TRANSFERRIN; TYROSINE;

EID: 58049194183     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfn211     Document Type: Article

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