Physical-chemical and solvent considerations in evaluating the influence of carbon chain length on the skin sensitization activity of 1-bromoalkanes

Toxicological Sciences

Volumn 107, Issue 1, 2009, Pages 78-84

  Siegel, Paul D ^a   Fedorowicz, Adam ^a   Butterworth, Leon ^a   Law, Brandon ^a   Anderson, Stacey E ^a   Snyder, James ^a   Beezhold, Don ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

Bromoalkane; Contact allergen; Murine local lymph node assay; Structure activity relationship

Indexed keywords

1 BROMOALKANE; 1 BROMODECANE DERIVATIVE; 1 BROMOHEXANE; ACETONE; ALKANE DERIVATIVE; CARBON; CONTACT ALLERGEN; HEXADECANE; HEXANE; OLIVE OIL; SOLVENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; LIPID SOLUBILITY; LOCAL LYMPH NODE ASSAY; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; ROOM TEMPERATURE; SKIN SENSITIZATION; SKIN SURFACE; SOLVATION; STRUCTURE ACTIVITY RELATION; VOLATILIZATION;

ANALYSIS OF VARIANCE; ANIMALS; CELL PROLIFERATION; DERMATITIS, CONTACT; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HYDROCARBONS, BROMINATED; HYPERSENSITIVITY; LOCAL LYMPH NODE ASSAY; LYMPH NODES; MICE; MICE, INBRED BALB C; PHYSICOCHEMICAL PHENOMENA; SOLUBILITY; SOLVENTS; VOLATILIZATION;

MURINAE;

EID: 58049194181     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfn212     Document Type: Article

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