Some features of primary and recrudescent amodiaquine-resistant Plasmodium falciparum infections in Nigerian children

Memorias do Instituto Oswaldo Cruz

Volumn 103, Issue 8, 2008, Pages 754-759

  Sowunmi, Akintunde ^b   Balogun, Sulayman T ^a   Gbotosho, Grace O ^a   Happi, Christian T ^a  

^a UNIVERSITY OF IBADAN   (Nigeria)

^b UNIVERSITY OF IBADAN   (Nigeria)

Author keywords

Amodiaquine; Children; Gametocyte sex ratio; Malaria; Nigeria; Recrudescence

Indexed keywords

PLASMODIUM FALCIPARUM;

EID: 58049179556     PISSN: 00740276     EISSN: 16788060     Source Type: Journal    
DOI: 10.1590/S0074-02762008000800002     Document Type: Article

References (29)

1. Anon 1994. Epi Info Version 6. A word processing data base and statistics program for public health on IBM-compatible microcomputers. Centers for Disease Control and Prevention, Atlanta, GA.
2. Anon 1999. SPSS for Windows Release 10.01 (standard version). SPSS Inc, Chicago, IL.
3. Anon 2004. National antimalarial treatment policy. Federal Ministry of Health, Abuja.
4. Carter R, Graves PM 1988. Gametocytes. In WH Wernsdorfer, I McGregor (eds.), Malaria. Principles and Practice of Malariology, Vol. I, Churchill Livingstone, Edingburgh, p. 253-303.
5. Fidock DA, Nomura T, Talley AK, Cooper RA, Dzekunov SM, Ferdig MT, Ursos LN, Sidhu AB, Naude B, Deitsch KW, Su X-Z, Wootton JC, Roepe PD, Wellems TE 2000. Mutations in P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance. Mol Cell 6: 861-871.
6. Gasasira AF, Dorsey G, Nzarubara B, Staedke SG, Nassau A, Rosenthal PJ, Kamya MR 2003. Comparative efficacy of aminoquinoline-antifolate combinations for the treatment of uncomplicated falciparum malaria in Kampala, Uganda. Am J Trop Med Hyg 68: 127-132.
7. Handunnetti SM, Gunewardena DM, Pathirana PPSL, Ekanayake K, Weerasinghe S, Mendis KN 1996. Features of recrudescent chloroquine-resistant Plasmodium falciparum infections confer a survival advantage on parasite and have implications for disease control. Trans R Soc Trop Med Hyg 90: 563-567.
8. Happi CT, Gbotosho GO, Folarin OA, Bolaji OM, Sowunmi A, Kyle DE, Milhous W, Wirth DF Oduola AMJ 2006. Association between mutations in Plasmodium falciparum chloroquine resistance transporter and P. falciparum multidrug resistance 1 genes and In vivo amodiaquine resistance in P. falciparum malaria-infected children in Nigeria. Am J Trop Med Hyg 75: 155-161.
9. Holmgren G, Gil J, Ferreira PM, Veiga MI, Obonyo CO, Bjorkman A 2006. Amodiaquine resistant Plasmodium falciparum malaria in vivo is associated with selection of pfcrt 76T and pfmdr 1 86Y. Inf Gen Evol 6: 309-314.
10. Ochong EO, Van Den Broek IVF, Keus K, Nzila A 2003. Association between chloroquine and amodiaquine resistance and allelic variation in the Plasmodium falciparum multiple drug resistance 1 gene and the chloroquine resistance transporter gene in isolates from the Upper Nile in southern Sudan. Am J Trop Med Hyg 69:184-187.
11. Pickering J, Read AF, Guerrero S, West SA 2000. Sex ratio and virulence in two species of lizard malaria parasites. Evol Ecol Res 2: 171-184.
12. Plowe CV, Cortese JF, Djimde A, Nwanyanwu OC, Watkins WM, Winstanley PA, Estrada-Franco JG, Mollinedo RE, Avila JC, Cespedes JL, Carter D, Dumbo O 1997. Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthetase and the epidemiologic patterns of pyrimethaminesulphadoxine use and resistance. J Inf Dis 176: 1590-1596.
13. Price R, Nosten F, Simpson JA, Luxemburger C, Paiphun L, ter Kuile F, van Vugt M, Chongsuphajaisiddhi T, White NJ 1999. Risk factors for gametocyte carriage in uncomplicated falciparum malaria. Am J Trop Med Hyg 60: 1019-1023.
14. Robert V, Awono-Ambene HP, Hesran J-YL, Trape J-F 2000. Gametocytaemia and infectivity to mosquitoes of patients with uncomplicated Plasmodium falciparum malaria attacks treated with chloroquine or sulfadoxine plus pyrimethamine. Am J Trop Med Hyg 62: 210-216.
15. Robert V, Read AF, Essong J, Chuinkam T, Mulder B, Verhave JP, Carnevale P 1996. Effects of gametocyte sex ratio on infectivity of Plasmodium falciparum to Anopheles gambiae. Trans R Soc Trop Med Hyg 90: 621-624.
16. Salako LA, Ajayi FO, Sowunmi A, Walker O 1990. Malaria in Nigeria: a revisit. Ann Trop Med Parasito! 84: 435-445.
17. Schellenberg D, Kahigwa E, Drakeley C, Malende A, Wigayi J, Msokame C, Aponte JJ, Tanner M, Mshinda H, Menendez C, Alonso PL 2002. The safety and efficacy of sulfadoxine-pyrimethamine, amodiaquine and their combination in the treatment of uncomplicated falciparum malaria. Am J Trop Med Hyg 67: 17-23.
18. Sowunmi A 2002. A randomized comparison of chloroquine, amodiaquine and their combination with pyrimethamine-sulfadoxine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children. Ann Trop Med Parasitol 96: 227-238.
19. Sowunmi A, Ayede AI, Falade AG, Ndikum VN, Falade CO, Happi TC, Oduola AMJ 2001. Randomized comparison of chloroquine and amodiaquine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children. Ann Trop MedParasitol 95: 549-558.
20. Sowunmi A, Balogun T, Gbotosho GO, Happi CT, Adedeji AA, Fehintola FA 2007a. Activities of amodiaquine, artesunate and artesunate-amodiaquine against asexual and sexual-stage parasites in falciparum malaria in children. Antimicrob Agent Chemother 51: 1694-1699.
21. Sowunmi A, Fateye BA 2003a. Asymptomatic, recrudescent, chloroquine-resistant, Plasmodium falciparum infections in Nigerian children: clinical and parasitological characteristics and implications for the transmission of drug-resistant parasites. Ann Trop Med Parasitol 97: 469-479.
22. Sowunmi A, Fateye BA 2003b. Gametocyte sex ratios in children with asymptomatic, recrudescent, pyrimethamine-sulfadoxine-resistant, Plasmodium falciparum malaria. Ann Trop Med Parasitol 97: 671-682.
23. Sowunmi A, Fateye BA, Adedeji AA, Fehintola FA, Happi TC 2004. Risk factors for gametocyte carriage in uncomplicated falciparum malaria in children. Parasitol 129: 255-262.
24. Sowunmi A, Gbotosho GO, Happi CT, Adedeji AA, Bolaji OM, Fehintola FA, Fateye BA, Oduola AMJ 2007b. Enhancement of the antimalarial efficacy of amodiaquine by chlorpheniramine in vivo. Mem Inst Oswaldo Cruz 102: 417-419.
25. Sowunmi A, Gbotosho GO, Happi CT, Adedeji AA, Fehintola FA, Folarin OA, Tambo E, Fateye BA 2007c. Therapeutic efficacy and effects of artemether-lumefantrine and amodiaquine-sulfalenepyrimethamine on gametocyte carriage in children with uncomplicated Plasmodium falciparum malaria southwestern Nigeria. Am J Trop Med Hyg 77: 235-241.
26. Sutherland CJ, Alloueche A, Curtis J, Drakeley CJ, Ord R, Duraisingh M, Greenwood BM, Pinder M, Warhurst DC, Targett GAT 2002. Gambian children successfully treated with chloroquine can harbor and transmit Plasmodium falciparum gametocytes carrying resistant genes. Am J Trop Med Hyg 67: 575-585.
27. von Seidlein L, Drakeley C, Greenwood B, Walraven G, Targett G 2001. Risk factors for gametocyte carriage in Gambian children. Am J Trop Med Hyg 65: 523-526.
28. WHO - World Health Organization 2000. Severe falciparum malaria. Trans R Soc Trop Med Hyg 94 (Suppl. 1): 1-90.
29. WHO - World Health Organization 2001. Antimalarial drug combination therapy. Report of a WHO technical consultation. WHO/ CDS/RBM/2001.35, WHO, Geneva.