Synthesis and antiproliferative activity of 3-amino-N-phenyl-1H-indazole-1-carboxamides

European Journal of Medicinal Chemistry

Volumn 44, Issue 1, 2009, Pages 165-178

  Raffa, Demetrio ^a   Maggio, Benedetta ^a   Cascioferro, Stella ^a   Raimondi, Maria Valeria ^a   Schillaci, Domenico ^a   Gallo, Giorgio ^a   Daidone, Giuseppe ^a   Plescia, Salvatore ^a   Meneghetti, Fiorella ^b   Bombieri, Gabriella ^b   Di Cristina, Antonietta ^c   Pipitone, Rosaria M ^c   Grimaudo, Stefania ^c   Tolomeo, Manlio ^c  

^a UNIVERSITY OF PALERMO   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c UNIVERSITY OF PALERMO   (Italy)

Author keywords

1H Indazole 1 carboxamides; Crystallographic study; G0 G1 arrest; pRb

Indexed keywords

3 AMINO N (4 BENZYLPHENYL) 1H INDAZOLE 1 CARBOXAMIDE; 3 AMINO N (4 BUTOXYPHENYL) 1H INDAZOLE 1 CARBOXAMIDE; 3 AMINO N PHENYL 1H INDAZOLE 1 CARBOXAMIDE DERIVATIVE; AMIDE; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; REACTION ANALYSIS; STRUCTURE ANALYSIS;

AMIDES; ANTINEOPLASTIC AGENTS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CRYSTALLOGRAPHY, X-RAY; HUMANS; INDAZOLES; MOLECULAR STRUCTURE; NEOPLASMS; RETINOBLASTOMA PROTEIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 57949110737     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.03.023     Document Type: Article

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