메뉴 건너뛰기




Volumn 8, Issue 3, 1996, Pages 111-120

Effect of the antitumor drug lonidamine on glucose metabolism of adriamycin-sensitive and -resistant human breast cancer cells

Author keywords

glucose metabolism; lonidamine; MCF 7 cells; mitochondrial hexokinase; multidrug resistance

Indexed keywords

ADENOSINE PHOSPHATE; ANTINEOPLASTIC AGENT; DOXORUBICIN; GLUCOSE; HEXOKINASE; LONIDAMINE;

EID: 0029952517     PISSN: 09650407     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (38)

References (56)
  • 2
    • 0023205811 scopus 로고
    • The cell biology of multiple drug resistance. Biochem. Pharmacol
    • 2. Beck, W. T. The cell biology of multiple drug resistance. Biochem. Pharmacol. 36:2879-2887; 1987.
    • (1987) , vol.36 , pp. 2879-2887
    • Beck, W.T.1
  • 5
    • 0025598007 scopus 로고
    • Biochemical basis of resistance to chemotherapy
    • 5. Master, J. R. W. Biochemical basis of resistance to chemotherapy. Radiother. Oncol. 19:297-305; 1990.
    • (1990) Radiother. Oncol. , vol.19 , pp. 297-305
    • Master, J.R.W.1
  • 6
    • 0023485346 scopus 로고
    • The phenomenon of pleiotropic drug resistance
    • De Vita, V. T.; Hellman, S.; Rosenberg, S. A., eds. Philadelphia: J. B. Lippincott
    • 6. Myers, C.; Cowan, K.; Sinha, B.; Chabner, B. The phenomenon of pleiotropic drug resistance. In: De Vita, V. T.; Hellman, S.; Rosenberg, S. A., eds. Important advances in oncology. Philadelphia: J. B. Lippincott; 1987:pp. 27-38.
    • (1987) Important Advances in Oncology , pp. 27-38
    • Myers, C.1    Cowan, K.2    Sinha, B.3    Chabner, B.4
  • 7
    • 0025612231 scopus 로고
    • Molecular mechanisms of drug resistance
    • 7. Hayes, J. D.; Wolfm, C. R. Molecular mechanisms of drug resistance. Biochem. J. 272:281-295; 1990.
    • (1990) Biochem. J. , vol.272 , pp. 281-295
    • Hayes, J.D.1    Wolfm, C.R.2
  • 8
    • 0023598266 scopus 로고
    • The molecular mechanism of multidrug resistance in tumor cells
    • 8. Robinson, I. B. The molecular mechanism of multidrug resistance in tumor cells. J. Clin. Physiol. Biochem. 5:140-151; 1987.
    • (1987) J. Clin. Physiol. Biochem. , vol.5 , pp. 140-151
    • Robinson, I.B.1
  • 9
    • 0026210867 scopus 로고
    • Multidrug resistance mediated by P-glycoprotein
    • 9. Schinkel, A. H.; Borst, P. Multidrug resistance mediated by P-glycoprotein. Semin. Cancer Biol. 2:213-226; 1991.
    • (1991) Semin. Cancer Biol. , vol.2 , pp. 213-226
    • Schinkel, A.H.1    Borst, P.2
  • 10
    • 0020578356 scopus 로고
    • Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines
    • 10. Kartner, N.; Riordan, J. R.; Ling, V. Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines. Science 221:1285-1288; 1983.
    • (1983) Science , vol.221 , pp. 1285-1288
    • Kartner, N.1    Riordan, J.R.2    Ling, V.3
  • 11
    • 0024279163 scopus 로고
    • The multidrug transporter, a double-edged sword
    • 11. Gottesman, M. M.; Pastan, I. The multidrug transporter, a double-edged sword. J. Biol. Chem. 263:12163-12166; 1988.
    • (1988) J. Biol. Chem. , vol.263 , pp. 12163-12166
    • Gottesman, M.M.1    Pastan, I.2
  • 12
    • 0025604425 scopus 로고
    • Evidence for daunomycin efflux from multidrug-resistant 2780 AD human ovarian carcinoma cells against a concentration gradient
    • 12. Lankelma, J.; Spoelstra, E. C.; Dekker, H.; Broxterman, H. J. Evidence for daunomycin efflux from multidrug-resistant 2780 AD human ovarian carcinoma cells against a concentration gradient. Biochem. Biophys. Acta 1055:217-222; 1990.
    • (1990) Biochem. Biophys. Acta , vol.1055 , pp. 217-222
    • Lankelma, J.1    Spoelstra, E.C.2    Dekker, H.3    Broxterman, H.J.4
  • 13
    • 0023930530 scopus 로고
    • Glucose metabolism in drug-sensitive and drug-resistant human breast cancer cells monitored by magnetic resonance spectroscopy
    • 13. Lyon, R. C.; Cohen, J. S.; Faustino, P. J.; Megnin, F.; Myers, C. E. Glucose metabolism in drug-sensitive and drug-resistant human breast cancer cells monitored by magnetic resonance spectroscopy. Cancer Res. 48: 870-877; 1988.
    • (1988) Cancer Res. , vol.48 , pp. 870-877
    • Lyon, R.C.1    Cohen, J.S.2    Faustino, P.J.3    Megnin, F.4    Myers, C.E.5
  • 14
    • 0027892859 scopus 로고
    • Glucose metabolism in adriamycin-sensitive and -resistant LoVo human colon carcinoma cells
    • 14. Fanciulli, M.; Bruno, T.; Castiglione, S.; Del Carlo, C.; Paggi, M. G.; Floridi, A. Glucose metabolism in adriamycin-sensitive and -resistant LoVo human colon carcinoma cells. Oncol. Res. 5:357-362; 1993.
    • (1993) Oncol. Res. , vol.5 , pp. 357-362
    • Fanciulli, M.1    Bruno, T.2    Castiglione, S.3    Del Carlo, C.4    Paggi, M.G.5    Floridi, A.6
  • 17
    • 0020519825 scopus 로고
    • Action of the antitumor and antispermatogenic agent lonidamine on electron transport in Ehrlich ascites tumor mitochondria
    • 17. Floridi, A.; Lehninger, A. L. Action of the antitumor and antispermatogenic agent lonidamine on electron transport in Ehrlich ascites tumor mitochondria. Arch. Biochem. Biophys. 266:73-83; 1983.
    • (1983) Arch. Biochem. Biophys. , vol.266 , pp. 73-83
    • Floridi, A.1    Lehninger, A.L.2
  • 18
    • 0017841405 scopus 로고
    • Tumor mitochondria and the bioenergetics of cancer cells
    • 18. Pedersen, P. L. Tumor mitochondria and the bioenergetics of cancer cells. Prog. Exp. Tumor Res. 22:190-274; 1978.
    • (1978) Prog. Exp. Tumor Res. , vol.22 , pp. 190-274
    • Pedersen, P.L.1
  • 24
    • 0025851306 scopus 로고
    • Cytotoxic effect of the association of BCNU with rhein or lonidamine on a human glioma cell line
    • 24. Floridi, A.; Gentile, F. P.; Bruno, T.; Fanciulli, M.; Paggi, M. G.; Zeuli, M.; Benassi, M. Cytotoxic effect of the association of BCNU with rhein or lonidamine on a human glioma cell line. Anticancer Res. 11:789-792; 1991.
    • (1991) Anticancer Res. , vol.11 , pp. 789-792
    • Floridi, A.1    Gentile, F.P.2    Bruno, T.3    Fanciulli, M.4    Paggi, M.G.5    Zeuli, M.6    Benassi, M.7
  • 27
    • 0021269151 scopus 로고
    • Lonidamine in primary malignant brain tumors
    • 27. Carapella, C. M.; Iandolo, B.; Delle Chiaie, S.; Riccio, A. Lonidamine in primary malignant brain tumors. Oncology 41 Suppl. 1:82-85; 1984.
    • (1984) Oncology , vol.41 , Issue.SUPPL. 1 , pp. 82-85
    • Carapella, C.M.1    Iandolo, B.2    Delle Chiaie, S.3    Riccio, A.4
  • 29
    • 0022553294 scopus 로고
    • Potentiation of radiation effects of two murine tumors by lonidamine
    • 29. Kim, J. H.; Alfieri, A. A.; Kim, S. H.; Young, C. W. Potentiation of radiation effects of two murine tumors by lonidamine. Cancer Res. 46:1120-1123; 1986.
    • (1986) Cancer Res. , vol.46 , pp. 1120-1123
    • Kim, J.H.1    Alfieri, A.A.2    Kim, S.H.3    Young, C.W.4
  • 32
    • 0001655507 scopus 로고
    • In vivo control of tumor growth by lonidamine and radiations, influence of the timing and sequence of drug: Administration and irradiation treatment
    • 32. Cividalli, A.; Gentile, F. P.; Alonzi, A.; Benassi, M.; Mauro, F.; Floridi, A. In vivo control of tumor growth by lonidamine and radiations, influence of the timing and sequence of drug: administration and irradiation treatment. Int. J. Oncol. 1:561-565; 1992.
    • (1992) Int. J. Oncol. , vol.1 , pp. 561-565
    • Cividalli, A.1    Gentile, F.P.2    Alonzi, A.3    Benassi, M.4    Mauro, F.5    Floridi, A.6
  • 33
    • 0027243611 scopus 로고
    • In vivo control of tumor growth with the association of lonidamine with radiation and/or hyperthermia
    • 33. Cividalli, A.; Gentile, F. P.; Begnozzi, L.; Chiatti, L.; Benassi, M.; Floridi, A. In vivo control of tumor growth with the association of lonidamine with radiation and/or hyperthermia. Int. J. Oncol. 2:791-795; 1993.
    • (1993) Int. J. Oncol. , vol.2 , pp. 791-795
    • Cividalli, A.1    Gentile, F.P.2    Begnozzi, L.3    Chiatti, L.4    Benassi, M.5    Floridi, A.6
  • 36
    • 20244386234 scopus 로고
    • Fluorouracil, doxorubicin, and cyclophosphamide vs. fluorouracil, doxorubicin, and cyclophosphamide plus lonidamine for the treatment of advanced breast cancer. A multicentric randomized clinical study
    • 36. Calabresi, F.; Di Lauro, L.; Marolla, P.; Gallo Curcio, C.; Paoletti, G.; Calabrò, A.; Giannarelli, D.; Ballatore, P.; Foggi, C.M.; Di Palma, M.; Stolfi, R.; Cortese, R. Fluorouracil, doxorubicin, and cyclophosphamide vs. fluorouracil, doxorubicin, and cyclophosphamide plus lonidamine for the treatment of advanced breast cancer. A multicentric randomized clinical study. Semin. Oncol. 18 (2 Suppl 4): 66-72; 1991.
    • (1991) Semin. Oncol. , vol.18 , Issue.2 SUPPL. 4 , pp. 66-72
    • Calabresi, F.1    Di Lauro, L.2    Marolla, P.3    Gallo Curcio, C.4    Paoletti, G.5    Calabrò, A.6    Giannarelli, D.7    Ballatore, P.8    Foggi, C.M.9    Di Palma, M.10    Stolfi, R.11    Cortese, R.12
  • 38
    • 0025776309 scopus 로고
    • Reversal of adriamycin resistance by lonidamine in a human breast cancer cell line
    • 38. Citro, G.; Cucco, C.; Verdina, A.; Zupi, G. Reversal of adriamycin resistance by lonidamine in a human breast cancer cell line. Br. J. Cancer 64:534-536; 1991.
    • (1991) Br. J. Cancer , vol.64 , pp. 534-536
    • Citro, G.1    Cucco, C.2    Verdina, A.3    Zupi, G.4
  • 39
    • 0025067416 scopus 로고
    • Effect of 2-deoxyglucose on drug-sensitive and drug-resistant human breast cancer cells: Toxicity and magnetic resonance spectroscopy studies of metabolism
    • 39. Kaplan, O.; Navon, G.; Lyon, R. C.; Faustino, P. J.; Straka, E. J.; Cohen, J. S. Effect of 2-deoxyglucose on drug-sensitive and drug-resistant human breast cancer cells: toxicity and magnetic resonance spectroscopy studies of metabolism. Cancer Res. 50:544-551; 1990.
    • (1990) Cancer Res. , vol.50 , pp. 544-551
    • Kaplan, O.1    Navon, G.2    Lyon, R.C.3    Faustino, P.J.4    Straka, E.J.5    Cohen, J.S.6
  • 40
    • 0011941272 scopus 로고
    • Studies in histochemistry. Determination of nucleic acids in microgram amounts of tissue
    • 40. Scott, F.; Fracastoro, A. P.; Taft, E. B. Studies in histochemistry. Determination of nucleic acids in microgram amounts of tissue. J. Histochem. Cytochem. 4:1-10; 1956.
    • (1956) J. Histochem. Cytochem. , vol.4 , pp. 1-10
    • Scott, F.1    Fracastoro, A.P.2    Taft, E.B.3
  • 41
    • 0002104059 scopus 로고
    • Determination with lactic dehydrogenase and DPN
    • Bergmeyer, H. U., ed. New York: Academic Press
    • 41. Hohorst, H. J. Determination with lactic dehydrogenase and DPN. In Bergmeyer, H. U., ed. Methods of enzymatic analysis. New York: Academic Press; 1965:pp. 266-270.
    • (1965) Methods of Enzymatic Analysis , pp. 266-270
    • Hohorst, H.J.1
  • 42
    • 0011941005 scopus 로고
    • 3H compounds
    • 3H compounds. Anal. Biochem. 7: 207-214; 1964.
    • (1964) Anal. Biochem. , vol.7 , pp. 207-214
    • Wu, R.1
  • 43
    • 0014010172 scopus 로고
    • The pentose cycle, triose phosphate isomerization, and lipogenesis in rat adipose tissue
    • 43. Katz, J. Landau, B. R.; Bartsch, G. E. The pentose cycle, triose phosphate isomerization, and lipogenesis in rat adipose tissue. J. Biol. Chem. 241:727-740; 1966.
    • (1966) J. Biol. Chem. , vol.241 , pp. 727-740
    • Katz, J.1    Landau, B.R.2    Bartsch, G.E.3
  • 44
    • 0014106530 scopus 로고
    • 14C and estimation of transaldolase, transketolase, the contribution of the pentose cycle and ribose phosphate synthesis
    • 14C and estimation of transaldolase, transketolase, the contribution of the pentose cycle and ribose phosphate synthesis. Biochemistry 6:2227-2247; 1967.
    • (1967) Biochemistry , vol.6 , pp. 2227-2247
    • Katz, J.1    Rognstad, R.2
  • 45
    • 0028626288 scopus 로고
    • Effect of the local anesthetic bupivacaine on the energy metabolism of Ehrlich ascites tumor cells
    • 45. Floridi, A.; Barbieri, R.; Pulselli, R.; Fanciulli, M.; Arcuri, E. Effect of the local anesthetic bupivacaine on the energy metabolism of Ehrlich ascites tumor cells. Oncol. Res. 6:593-601; 1994.
    • (1994) Oncol. Res. , vol.6 , pp. 593-601
    • Floridi, A.1    Barbieri, R.2    Pulselli, R.3    Fanciulli, M.4    Arcuri, E.5
  • 46
    • 0020562212 scopus 로고
    • Intracellular localization and properties of particulate hexokinase in the Novikoff ascites tumor
    • 46. Parry, D.; Pedersen, P. L. Intracellular localization and properties of particulate hexokinase in the Novikoff ascites tumor. J. Biol. Chem. 258:10904-10912; 1983.
    • (1983) J. Biol. Chem. , vol.258 , pp. 10904-10912
    • Parry, D.1    Pedersen, P.L.2
  • 47
    • 0022773316 scopus 로고
    • Effect of zwitterionic buffers on measurement of small masses of protein with bicinchoninic acid
    • 47. Kaushal, V.; Barnes, L. D. Effect of zwitterionic buffers on measurement of small masses of protein with bicinchoninic acid. Anal. Biochem. 157:291-294; 1986.
    • (1986) Anal. Biochem. , vol.157 , pp. 291-294
    • Kaushal, V.1    Barnes, L.D.2
  • 48
    • 0021996231 scopus 로고
    • Simultaneous extraction and reverse-phase high-performance liquid chromatographic determination of adenine and pyridine nucleotides in human red blood cells
    • 48. Stocchi, V.; Cucchiarini, M.; Magnani, L.; Chiarantini, P.; Crescentini, G. Simultaneous extraction and reverse-phase high-performance liquid chromatographic determination of adenine and pyridine nucleotides in human red blood cells. Anal. Biochem. 146:118-124; 1985.
    • (1985) Anal. Biochem. , vol.146 , pp. 118-124
    • Stocchi, V.1    Cucchiarini, M.2    Magnani, L.3    Chiarantini, P.4    Crescentini, G.5
  • 49
    • 0024237766 scopus 로고
    • Functional significance of mitochondrial bound hexokinase in tumor cell metabolism. Evidence for preferential phosphorylation of glucose by intramitochondrially generated ATP
    • 49. Arora, K. K.; Pedersen, P. L. Functional significance of mitochondrial bound hexokinase in tumor cell metabolism. Evidence for preferential phosphorylation of glucose by intramitochondrially generated ATP. J. Biol. Chem. 263:17422-17428; 1988.
    • (1988) J. Biol. Chem. , vol.263 , pp. 17422-17428
    • Arora, K.K.1    Pedersen, P.L.2
  • 51
    • 0023840423 scopus 로고
    • Differential effect of lonidamine on the plasma membrane ultrastructure of normal and leukemic human lymphocytes
    • 51. Arancia, G.; Malorni, W.; Crateri Trovalusci, P.; Isacchi, G.; Giannella, G.; De Martino, C. Differential effect of lonidamine on the plasma membrane ultrastructure of normal and leukemic human lymphocytes. Exp. Mol. Pathol. 48:37-47; 1988.
    • (1988) Exp. Mol. Pathol. , vol.48 , pp. 37-47
    • Arancia, G.1    Malorni, W.2    Crateri Trovalusci, P.3    Isacchi, G.4    Giannella, G.5    De Martino, C.6
  • 52
    • 0001784903 scopus 로고
    • Comparison of action of anti-neoplastic drug lonidamine between drug sensitive and multidrug resistant MCF-7 human breast cancer cells
    • Nice, France, August
    • 52. Vivi, A.; Tassini, M.; Navon, G.; Kaplan, O. Comparison of action of anti-neoplastic drug lonidamine between drug sensitive and multidrug resistant MCF-7 human breast cancer cells. Proceedings of the Third International Congress of the Magnetic Resonance Society, Nice, France, August 1995:pp. 1699.
    • (1995) Proceedings of the Third International Congress of the Magnetic Resonance Society , pp. 1699
    • Vivi, A.1    Tassini, M.2    Navon, G.3    Kaplan, O.4
  • 53
    • 0001859032 scopus 로고
    • Clinical significance of a rearranged hexokinase isozymes expression in neoplastic phentype: The astrocytoma model
    • Cimino, F.; Birkmayer, G. D.; Klavins, J. V.; Plimentel, E.; Salvatore, F., eds. Berlin: Walter de Gruyter & Co
    • 53. Paggi, M. G.; Caputo, A. Clinical significance of a rearranged hexokinase isozymes expression in neoplastic phentype: the astrocytoma model. In: Cimino, F.; Birkmayer, G. D.; Klavins, J. V.; Plimentel, E.; Salvatore, F., eds. Human Tumor Markers. Berlin: Walter de Gruyter & Co; 1987:pp. 869-881.
    • (1987) Human Tumor Markers , pp. 869-881
    • Paggi, M.G.1    Caputo, A.2
  • 54
    • 0025045112 scopus 로고
    • Human erythrocyte insulin receptor downregulation is accompanied by a transient decrease in membrane order
    • 54. Santini, M. T.; Indovina, P. L.; Simmons, J. R.; Scott, W. P. Human erythrocyte insulin receptor downregulation is accompanied by a transient decrease in membrane order. Biochem. Biophys. Acta 1054:333-336; 1990.
    • (1990) Biochem. Biophys. Acta , vol.1054 , pp. 333-336
    • Santini, M.T.1    Indovina, P.L.2    Simmons, J.R.3    Scott, W.P.4
  • 55
    • 0022442571 scopus 로고
    • Membrane structural/functional perturbations induced by gossypol. Effects on membrane order, liposome permeability, and insulin-sensitive hexose transport
    • 55. De Peyster, A.; Hyslop, P. A.; Kuhn, C. E.; Sauerheber, R. D. Membrane structural/functional perturbations induced by gossypol. Effects on membrane order, liposome permeability, and insulin-sensitive hexose transport. Biochem. Pharmacol. 35: 3293-3300; 1986.
    • (1986) Biochem. Pharmacol. , vol.35 , pp. 3293-3300
    • De Peyster, A.1    Hyslop, P.A.2    Kuhn, C.E.3    Sauerheber, R.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.