Propylthiouracil, independent of its antithyroid effect, decreases VSMC collagen expression

Basic Research in Cardiology

Volumn 104, Issue 1, 2009, Pages 60-68

  Chen, Wei Jan ^a   Pang, Jong Hwei S ^b   Lin, Kwang Huei ^b   Yang, Su Hui ^b  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

Atherosclerosis; Balloon injury; Collagen; Propylthiouracil; Transforming growth factor ; Vascular smooth muscle cells

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 3; DACTINOMYCIN; MESSENGER RNA; PROPYLTHIOURACIL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY INTIMA; ARTERY INTIMA PROLIFERATION; ARTERY RUPTURE; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CAROTID ARTERY INJURY; CONTROLLED STUDY; DOWN REGULATION; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG MECHANISM; GENE CONSTRUCT; GENETIC TRANSFECTION; IMMUNOCYTOCHEMISTRY; MALE; NONHUMAN; NORTHERN BLOTTING; PROMOTER REGION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN SYNTHESIS INHIBITION; RAT; RNA STABILITY; SMOOTH MUSCLE FIBER; UPREGULATION; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

ANIMALS; ANTITHYROID AGENTS; ATHEROSCLEROSIS; BLOTTING, NORTHERN; CAROTID ARTERIES; COLLAGEN; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; MALE; MUSCLE, SMOOTH, VASCULAR; PROPYLTHIOURACIL; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 57949109285     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-008-0746-8     Document Type: Article

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