Genes required for ethanol tolerance and utilization in Saccharomyces cerevisiae

American Journal of Enology and Viticulture

Volumn 59, Issue 4, 2008, Pages 401-411

  Kumar, G Renuka ^a   Goyashiki, Renko ^a   Ramakrishnan, Vidhya ^a   Karpel, Jonathan E ^a,b   Bisson, Linda F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF WYOMING   (United States)

Author keywords

Ethanol tolerance; Ethanol utilization; Saccharomyces

Indexed keywords

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 57949100624     PISSN: 00029254     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Alexandre, H., and C. Charpentier. 1998. Biochemical aspects of stuck and sluggish fermentations in grape must. J. Ind. Microbiol. Biotechnol. 20:20-27.
2. Alexandre, H., V. Ansanay-Galeote, S. Dequin, and B. Blondin. 2001. Global gene expression during short-term ethanol stress in Saccharomyces cerevisiae. FEBS Lett. 498:98-103.
3. Bennetzen, J.L., and B.D. Hall. 1982. The primary structure of the Saccharomyces cerevisiae gene for alcohol dehydrogenase. J. Biol. Chem. 257:3018-3025.
4. Bisson, L.F., and D.E. Block. 2002. Ethanol tolerance in Saccharomyces. In Biodiversity and Biotechnology of Wine Yeasts. M. Ciani (Ed.), pp. 85-98. Research Signpost India.
5. Boulton, R.B., V.L. Singleton, L.F Bisson, and R.E. Kunkee. 1996. Principles and Practices of Winemaking. Chapman & Hall, New York.
6. Chu, D.S., B. Pishvaee, and G.S. Payne. 1996. The light chain subunit is required for clathrin function in Saccharomyces cerevisiae. J. Biol. Chem. 271:33123-33130.
7. D'Amore, T., C.J. Panchal, I. Russell, and G.G. Stewart. 1990. A study of ethanol tolerance in yeast. Crit. Rev. Biotechnol. 9:287-304.
8. Dombek, K.M., and L.O. Ingram. 1986. Magnesium limitation and its role in apparent toxicity of ethanol during yeast fermentation. Appl. Environ. Microbiol. 52:975-981.
9. Dormer, U.H., J. Westwater, D.W. Stephen, and D.J. Jamieson. 2002. Oxidant regulation of the Saccharomyces cerevisiae GSH1 gene. Biochim. Biophys. Acta 1576:23-29.
10. Fujita, K., A. Matsuyama, Y. Kobayashi, and H. Iwahashi. 2006. The genome-wide screening of yeast deletion mutants to identify genes required for tolerance to ethanol and other alcohols. FEMS Yeast Res. 6:744-750.
11. Geissler, S., K. Siegers, and E. Schiebel. 1998. A novel protein complex promoting formation of functional α- and γ-tubulin. EMBO J. 17:953-966.
12. Grant, C.M. 2002. Role of the glutathione/glutaredoxin and thioredoxin systems in yeast growth and response to stress conditions. Mol. Microbiol. 39:533-541.
13. Herman, P.K., and S.R. Emr. 1990. Characterization of VSP34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae. Mol. Cell Biol. 10:6742-6754.
14. Hirasawa, T., K. Yoshikawa, Y. Nakakura, K. Nagahisa, C. Furusawa, Y. Katakura, H. Shimizu, and S. Shioya. Identification of target genes conferring ethanol stress tolerance to Saccharomyces cerevisiae based on DNA microarray data analysis. J. Biotechnol. 131:34-44.
15. Hu, X.H., M.H. Wang, T. Tan. J.R. Li, H. Yang, L. Leach, R.M. Zhang, and Z.W. Luo. 2007. Genetic dissection of ethanol tolerance in the budding yeast Saccharomyces cerevisiae. Genetics 175:1479-1487.
16. Ingram, L.O., and T.M. Buttke. 1984. Effects of alcohols on microorganisms. Adv. Microbial Physiol. 25:253-300.
17. Jones, R.P. 1989. Biological principles for the effects of ethanol. Enzyme Microb. Technol. 11:130-150.
18. Kubota, S., I. Takeo, K. Kume, M. Kanai, A. Shitamukai, M. Mizunuma, T. Miyakawa, H. Shimoi, H. Iefuji, and D. Hirata. 2004. Effect of ethanol on cell growth of budding yeast: Genes that are important for cell growth in the presence of ethanol. Biosei. Biotechnol. Biochem. 68:968-972.
19. Leskovac, V., S. Trivic, and D. Pericin. 2002. The three zinc containing alcohol dehydrogenases from baker's yeast Saccharomyces cerevisiae. FEMS Yeast Res. 2:481-494.
20. Marks, V.D., S.J.H. Sui, D. Erasmus, G.K. van der Merwe, J. Brumm, W.W. Wasserman, J. Bryan, and H.J.J. van Vuuren. 2008. Dynamics of the yeast transcriptome during wine fermentation reveals a novel fermentation stress response. FEMS Yeast Res. 8:35-52.
21. Ohtake, Y., and S. Yabuuchi. 1991. Molecular cloning of the gamma glutamlycysteine synthetase gene of Saccharomyces cerevisiae. Yeast 7:953-961.
22. Pina, C., C. Santos, J.A. Couto, and T. Hogg. 2003. Ethanol tolerance of five non-Saccharomyces wine yeasts in comparison with a strain of Saccharomyces cerevisiae - Influence of different culture conditions. Food Microbiol. 21:439-447.
23. Steber, C.M., and R.E. Esposito.1995. UME6 is a central component of a developmental regulatory switch controlling meiosis-specific gene expression. Proc. Natl. Acad. Sci. USA 92:12490-12494.
24. Steinmetz, L.M., C. Scharfe, A.M. Deutschbauer, D. Mokranjac, Z.S. Herman, T. Jones, A.M. Chu, G. Giaever, H. Prokisch, P.J. Oefner, and R.W. Davis. 2002. Systematic screen for human disease genes in yeast. Nat. Genet. 31:400-404.
25. Strich, R., R.T. Surosky, C. Steber, E. Dubois, F. Messenguy, and R.E. Esposito. 1994. UME6 is a key regulator of nitrogen repression and meiotic development. Genes Dev. 8:796-810.
26. Takahashi, T., H. Shimoi, and K. Ito. 2001. Identification of genes required for growth under ethanol stress using transposon mutagenesis in Saccharomyces cerevisiae. Mol. Genet. Genomics 265:1112-1119.
27. Van Voorst, F., J. Houghton-Larsen, L. Jonson, M.C. Kielland-Brandt, and A. Brandt. 2006. Genome-wide identification of genes required for growth of Saccharomyces cerevisiae under ethanol stress. Yeast 23:351-359.
28. Van Zyl, W., W. Huang, A.A. Sneddon, M. Stark, S. Camier, M. Werner, C. Marck, A. Sentanac, and J.R. Broach. 1992. Inactivation of the protein phosphatase 2A regulatory subunit A results in morphological and transcriptional defects in Saccharomyces cerevisiae. Mol. Cell Biol. 12:4946-4959.
29. Van Zyl, W.H., N. Willis, and J.R. Broach. 1989. A general screen for mutants of Saccharomyces cerevisiae deficient in tRNA biosynthesis. Genetics 123:55-68.
30. Wang, Y., and D.J. Burke. 1997 Cdc55p, the B-type regulatory subunit of protein phosphatase A, has multiple functions in mitosis and is required for the kinetochore/spindle checkpoint in Saccharomyces cerevisiae. Mol. Cell Biol. 17:620-626.
31. Williams, R.M., M. Primig, B.K. Washburn, E.A. Winzeler, M. Bellis, C. Sarrauste de Menthiere, R.W. Davis, and R.E. Esposito. 2002. The Ume6 regulon coordinates metabolic and meiotic gene expression in yeast. Proc. Natl. Acad. Sci. USA 99:13431-13436.
32. Winzeler, E.A., et al. 1999. Functional characterization of the Saccharomyces cerevisiae genome by gene deletion and parallel analysis. Science 285:901-906.
33. Yazawa, H., H. Iwahashi, and H. Uemura. 2007. Disruption of URA7 and GAL6 improves the ethanol tolerance and fermentation capacity of Saccharomyces cerevisiae. Yeast 24:551-560.