Synthesis and anti-HIV-1 integrase activities of 3-aroyl-2,3-dihydro-1,1-dioxo-1,4,2-benzodithiazines

European Journal of Medicinal Chemistry

Volumn 44, Issue 1, 2009, Pages 190-196

  Brzozowski, Zdzisław ^a   Saczewski, Franciszek ^a   Sławiński, Jarosław ^a   Sanchez, Tino ^b   Neamati, Nouri ^b  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

3 Aroyl 2,3 dihydro 1,1 dioxo 1,4,2 benzodithiazines; HIV 1 integrase inhibitors; Synthesis

Indexed keywords

3 (4 BROMOBENZOYL) 6 CHLORO 7 METHYL 2,3 DIHYDRO 1,1 DIOXO 1,4,2 BENZODITHIAZINE; 3 AROYL 2,3 DIHYDRO 1,1 DIOXO 1,4,2 BENZODITHIAZINE DERIVATIVE; INTEGRASE INHIBITOR; THIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG BINDING; DRUG BINDING SITE; DRUG POTENCY; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS 1; IC 50;

ANTI-HIV AGENTS; BENZENE DERIVATIVES; BINDING SITES; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; HUMANS; INHIBITORY CONCENTRATION 50; MUTATION, MISSENSE; THIAZINES;

EID: 57949095950     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.02.004     Document Type: Article

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