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Volumn 30, Issue 1, 2009, Pages 25-34

Current concepts and treatment advances in systemic mastocytosis;Actualités sur la compréhension et le traitement des mastocytoses systémiques

Author keywords

C Kit; D816V; Mastocytosis; Rapamycin; Treatment

Indexed keywords

BORTEZOMIB; BUDESONIDE; CLADRIBINE; COTRIMOXAZOLE; DENILEUKIN DIFTITOX; IMATINIB; LENALIDOMIDE; MIDOSTAURIN; PAROXETINE; RAPAMYCIN; STEM CELL FACTOR; STEM CELL FACTOR RECEPTOR; TANDUTINIB; VALACICLOVIR;

EID: 57849120363     PISSN: 02488663     EISSN: 17683122     Source Type: Journal    
DOI: 10.1016/j.revmed.2008.01.025     Document Type: Short Survey
Times cited : (19)

References (60)
  • 2
    • 0024271215 scopus 로고
    • Systemic mast cell disease. Analysis of 58 cases and literature review
    • Travis W.D., Li C.Y., Bergstralh E.J., Yam L.T., and Swee R.G. Systemic mast cell disease. Analysis of 58 cases and literature review. Medicine (Baltimore) 67 6 (1988) 345-368
    • (1988) Medicine (Baltimore) , vol.67 , Issue.6 , pp. 345-368
    • Travis, W.D.1    Li, C.Y.2    Bergstralh, E.J.3    Yam, L.T.4    Swee, R.G.5
  • 3
    • 0032828882 scopus 로고    scopus 로고
    • Early signaling pathways activated by c-Kit in hematopoietic cells
    • Linnekin D. Early signaling pathways activated by c-Kit in hematopoietic cells. Int J Biochem Cell Biol 31 10 (1999) 1053-1074
    • (1999) Int J Biochem Cell Biol , vol.31 , Issue.10 , pp. 1053-1074
    • Linnekin, D.1
  • 4
    • 0027359443 scopus 로고
    • Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product
    • Furitsu T., Tsujimura T., Tono T., Ikeda H., Kitayama H., Koshimizu U., et al. Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product. J Clin Invest 92 4 (1993) 1736-1744
    • (1993) J Clin Invest , vol.92 , Issue.4 , pp. 1736-1744
    • Furitsu, T.1    Tsujimura, T.2    Tono, T.3    Ikeda, H.4    Kitayama, H.5    Koshimizu, U.6
  • 5
    • 0030451499 scopus 로고    scopus 로고
    • Role of c-kit receptor tyrosine kinase in the development, survival and neoplastic transformation of mast cells
    • Tsujimura T. Role of c-kit receptor tyrosine kinase in the development, survival and neoplastic transformation of mast cells. Pathol Int 46 12 (1996) 933-938
    • (1996) Pathol Int , vol.46 , Issue.12 , pp. 933-938
    • Tsujimura, T.1
  • 6
    • 3442893823 scopus 로고    scopus 로고
    • The biology of Kit in disease and the application of pharmacogenetics
    • quiz 20
    • Akin C., and Metcalfe D.D. The biology of Kit in disease and the application of pharmacogenetics. J Allergy Clin Immunol 114 1 (2004) 13-19 quiz 20
    • (2004) J Allergy Clin Immunol , vol.114 , Issue.1 , pp. 13-19
    • Akin, C.1    Metcalfe, D.D.2
  • 7
    • 0036207241 scopus 로고    scopus 로고
    • Kit and c-kit mutations in mastocytosis: a short overview with special reference to novel molecular and diagnostic concepts
    • Feger F., Ribadeau Dumas A., Leriche L., Valent P., and Arock M. Kit and c-kit mutations in mastocytosis: a short overview with special reference to novel molecular and diagnostic concepts. Int Arch Allergy Immunol 127 2 (2002) 110-114
    • (2002) Int Arch Allergy Immunol , vol.127 , Issue.2 , pp. 110-114
    • Feger, F.1    Ribadeau Dumas, A.2    Leriche, L.3    Valent, P.4    Arock, M.5
  • 8
    • 0028856070 scopus 로고
    • Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder
    • Nagata H., Worobec A.S., Oh C.K., Chowdhury B.A., Tannenbaum S., Suzuki Y., et al. Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder. Proc Natl Acad Sci USA 92 23 (1995) 10560-10564
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.23 , pp. 10560-10564
    • Nagata, H.1    Worobec, A.S.2    Oh, C.K.3    Chowdhury, B.A.4    Tannenbaum, S.5    Suzuki, Y.6
  • 9
    • 33749368009 scopus 로고    scopus 로고
    • KIT mutation in mast cells and other bone marrow hematopoietic cell lineages in systemic mast cell disorders: a prospective study of the Spanish Network on Mastocytosis (REMA) in a series of 113 patients
    • Garcia-Montero A.C., Jara-Acevedo M., Teodosio C., Sanchez M.L., Nunez R., Prados A., et al. KIT mutation in mast cells and other bone marrow hematopoietic cell lineages in systemic mast cell disorders: a prospective study of the Spanish Network on Mastocytosis (REMA) in a series of 113 patients. Blood 108 7 (2006) 2366-2372
    • (2006) Blood , vol.108 , Issue.7 , pp. 2366-2372
    • Garcia-Montero, A.C.1    Jara-Acevedo, M.2    Teodosio, C.3    Sanchez, M.L.4    Nunez, R.5    Prados, A.6
  • 10
    • 13044305857 scopus 로고    scopus 로고
    • Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis
    • Longley Jr. B.J., Metcalfe D.D., Tharp M., Wang X., Tyrrell L., Lu S.Z., et al. Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis. Proc Natl Acad Sci USA 96 4 (1999) 1609-1614
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.4 , pp. 1609-1614
    • Longley Jr., B.J.1    Metcalfe, D.D.2    Tharp, M.3    Wang, X.4    Tyrrell, L.5    Lu, S.Z.6
  • 12
    • 1842579440 scopus 로고    scopus 로고
    • A novel form of mastocytosis associated with a transmembrane c-kit mutation and response to imatinib
    • Akin C., Fumo G., Yavuz A.S., Lipsky P.E., Neckers L., and Metcalfe D.D. A novel form of mastocytosis associated with a transmembrane c-kit mutation and response to imatinib. Blood 103 8 (2004) 3222-3225
    • (2004) Blood , vol.103 , Issue.8 , pp. 3222-3225
    • Akin, C.1    Fumo, G.2    Yavuz, A.S.3    Lipsky, P.E.4    Neckers, L.5    Metcalfe, D.D.6
  • 13
    • 0038731316 scopus 로고    scopus 로고
    • Juxtamembrane mutant V560GKit is more sensitive to Imatinib (STI571) compared with wild-type c-kit whereas the kinase domain mutant D816VKit is resistant
    • Frost M.J., Ferrao P.T., Hughes T.P., and Ashman L.K. Juxtamembrane mutant V560GKit is more sensitive to Imatinib (STI571) compared with wild-type c-kit whereas the kinase domain mutant D816VKit is resistant. Mol Cancer Ther 1 12 (2002) 1115-1124
    • (2002) Mol Cancer Ther , vol.1 , Issue.12 , pp. 1115-1124
    • Frost, M.J.1    Ferrao, P.T.2    Hughes, T.P.3    Ashman, L.K.4
  • 14
    • 32844455834 scopus 로고    scopus 로고
    • A novel K509I mutation of KIT identified in familial mastocytosis-in vitro and in vivo responsiveness to imatinib therapy
    • Zhang L.Y., Smith M.L., Schultheis B., Fitzgibbon J., Lister T.A., Melo J.V., et al. A novel K509I mutation of KIT identified in familial mastocytosis-in vitro and in vivo responsiveness to imatinib therapy. Leuk Res 30 4 (2006) 373-378
    • (2006) Leuk Res , vol.30 , Issue.4 , pp. 373-378
    • Zhang, L.Y.1    Smith, M.L.2    Schultheis, B.3    Fitzgibbon, J.4    Lister, T.A.5    Melo, J.V.6
  • 15
    • 24144503371 scopus 로고    scopus 로고
    • Novel germline mutation of KIT associated with familial gastrointestinal stromal tumors and mastocytosis
    • Hartmann K., Wardelmann E., Ma Y., Merkelbach-Bruse S., Preussner L.M., Woolery C., et al. Novel germline mutation of KIT associated with familial gastrointestinal stromal tumors and mastocytosis. Gastroenterology 129 3 (2005) 1042-1046
    • (2005) Gastroenterology , vol.129 , Issue.3 , pp. 1042-1046
    • Hartmann, K.1    Wardelmann, E.2    Ma, Y.3    Merkelbach-Bruse, S.4    Preussner, L.M.5    Woolery, C.6
  • 17
    • 26844504764 scopus 로고    scopus 로고
    • Accident vasculaire cérébral sur dissection artérielle au cours des mastocytoses systémiques: une association non-fortuite ? À propos de deux cas
    • Larroche C., Chadenat M.L., Chaunu M.P., Abad S., Casassus P., and Dhote R. Accident vasculaire cérébral sur dissection artérielle au cours des mastocytoses systémiques: une association non-fortuite ? À propos de deux cas. Rev Med Interne 26 10 (2005) 820-823
    • (2005) Rev Med Interne , vol.26 , Issue.10 , pp. 820-823
    • Larroche, C.1    Chadenat, M.L.2    Chaunu, M.P.3    Abad, S.4    Casassus, P.5    Dhote, R.6
  • 19
    • 27244455903 scopus 로고    scopus 로고
    • Mastocytose systémique
    • Fain O., Stirnemann J., and Lortholary O. Mastocytose systémique. Rev Prat 55 15 (2005) 1629-1636
    • (2005) Rev Prat , vol.55 , Issue.15 , pp. 1629-1636
    • Fain, O.1    Stirnemann, J.2    Lortholary, O.3
  • 20
    • 34250796815 scopus 로고    scopus 로고
    • Mastocytosis: state of the art
    • Horny H.P., Sotlar K., and Valent P. Mastocytosis: state of the art. Pathobiology 74 2 (2007) 121-132
    • (2007) Pathobiology , vol.74 , Issue.2 , pp. 121-132
    • Horny, H.P.1    Sotlar, K.2    Valent, P.3
  • 21
    • 18444416819 scopus 로고    scopus 로고
    • Serum tryptase levels in patients with mastocytosis: correlation with mast cell burden and implication for defining the category of disease
    • Sperr W.R., Jordan J.H., Fiegl M., Escribano L., Bellas C., Dirnhofer S., et al. Serum tryptase levels in patients with mastocytosis: correlation with mast cell burden and implication for defining the category of disease. Int Arch Allergy Immunol 128 2 (2002) 136-141
    • (2002) Int Arch Allergy Immunol , vol.128 , Issue.2 , pp. 136-141
    • Sperr, W.R.1    Jordan, J.H.2    Fiegl, M.3    Escribano, L.4    Bellas, C.5    Dirnhofer, S.6
  • 22
    • 0033932870 scopus 로고    scopus 로고
    • Serum tryptase and the laboratory diagnosis of systemic mastocytosis
    • Schwartz L.B., and Irani A.M. Serum tryptase and the laboratory diagnosis of systemic mastocytosis. Hematol Oncol Clin North Am 14 3 (2000) 641-657
    • (2000) Hematol Oncol Clin North Am , vol.14 , Issue.3 , pp. 641-657
    • Schwartz, L.B.1    Irani, A.M.2
  • 23
    • 0036454699 scopus 로고    scopus 로고
    • Treatment of adult systemic mastocytosis with interferon-alpha: results of a multicentre phase II trial on 20 patients
    • Casassus P., Caillat-Vigneron N., Martin A., Simon J., Gallais V., Beaudry P., et al. Treatment of adult systemic mastocytosis with interferon-alpha: results of a multicentre phase II trial on 20 patients. Br J Haematol 119 4 (2002) 1090-1097
    • (2002) Br J Haematol , vol.119 , Issue.4 , pp. 1090-1097
    • Casassus, P.1    Caillat-Vigneron, N.2    Martin, A.3    Simon, J.4    Gallais, V.5    Beaudry, P.6
  • 24
    • 0035945661 scopus 로고    scopus 로고
    • Treatment of systemic mast-cell disease with cladribine
    • Tefferi A., Li C.Y., Butterfield J.H., and Hoagland H.C. Treatment of systemic mast-cell disease with cladribine. N Engl J Med 344 4 (2001) 307-309
    • (2001) N Engl J Med , vol.344 , Issue.4 , pp. 307-309
    • Tefferi, A.1    Li, C.Y.2    Butterfield, J.H.3    Hoagland, H.C.4
  • 25
    • 0034663031 scopus 로고    scopus 로고
    • Soluble stem cell factor receptor (CD117) and IL-2 receptor alpha chain (CD25) levels in the plasma of patients with mastocytosis: relationships to disease severity and bone marrow pathology
    • Akin C., Schwartz L.B., Kitoh T., Obayashi H., Worobec A.S., Scott L.M., et al. Soluble stem cell factor receptor (CD117) and IL-2 receptor alpha chain (CD25) levels in the plasma of patients with mastocytosis: relationships to disease severity and bone marrow pathology. Blood 96 4 (2000) 1267-1273
    • (2000) Blood , vol.96 , Issue.4 , pp. 1267-1273
    • Akin, C.1    Schwartz, L.B.2    Kitoh, T.3    Obayashi, H.4    Worobec, A.S.5    Scott, L.M.6
  • 26
    • 0034986344 scopus 로고    scopus 로고
    • Diagnosis of mastocytosis: general histopathological aspects, morphological criteria, and immunohistochemical findings
    • Horny H.P., and Valent P. Diagnosis of mastocytosis: general histopathological aspects, morphological criteria, and immunohistochemical findings. Leuk Res 25 7 (2001) 543-551
    • (2001) Leuk Res , vol.25 , Issue.7 , pp. 543-551
    • Horny, H.P.1    Valent, P.2
  • 27
    • 0034983045 scopus 로고    scopus 로고
    • Diagnostic criteria and classification of mastocytosis: a consensus proposal
    • Valent P., Horny H.P., Escribano L., Longley B.J., Li C.Y., Schwartz L.B., et al. Diagnostic criteria and classification of mastocytosis: a consensus proposal. Leuk Res 25 7 (2001) 603-625
    • (2001) Leuk Res , vol.25 , Issue.7 , pp. 603-625
    • Valent, P.1    Horny, H.P.2    Escribano, L.3    Longley, B.J.4    Li, C.Y.5    Schwartz, L.B.6
  • 28
    • 0034987361 scopus 로고    scopus 로고
    • Immunohistochemical properties of bone marrow mast cells in systemic mastocytosis: evidence for expression of CD2, CD117/Kit, and bcl-x(L)
    • Jordan J.H., Walchshofer S., Jurecka W., Mosberger I., Sperr W.R., Wolff K., et al. Immunohistochemical properties of bone marrow mast cells in systemic mastocytosis: evidence for expression of CD2, CD117/Kit, and bcl-x(L). Hum Pathol 32 5 (2001) 545-552
    • (2001) Hum Pathol , vol.32 , Issue.5 , pp. 545-552
    • Jordan, J.H.1    Walchshofer, S.2    Jurecka, W.3    Mosberger, I.4    Sperr, W.R.5    Wolff, K.6
  • 29
    • 0034983239 scopus 로고    scopus 로고
    • Morphologic properties of neoplastic mast cells: delineation of stages of maturation and implication for cytological grading of mastocytosis
    • Sperr W.R., Escribano L., Jordan J.H., Schernthaner G.H., Kundi M., Horny H.P., et al. Morphologic properties of neoplastic mast cells: delineation of stages of maturation and implication for cytological grading of mastocytosis. Leuk Res 25 7 (2001) 529-536
    • (2001) Leuk Res , vol.25 , Issue.7 , pp. 529-536
    • Sperr, W.R.1    Escribano, L.2    Jordan, J.H.3    Schernthaner, G.H.4    Kundi, M.5    Horny, H.P.6
  • 30
    • 0041411106 scopus 로고    scopus 로고
    • Diagnosis and treatment of systemic mastocytosis: state of the art
    • Valent P., Akin C., Sperr W.R., Horny H.P., Arock M., Lechner K., et al. Diagnosis and treatment of systemic mastocytosis: state of the art. Br J Haematol 122 5 (2003) 695-717
    • (2003) Br J Haematol , vol.122 , Issue.5 , pp. 695-717
    • Valent, P.1    Akin, C.2    Sperr, W.R.3    Horny, H.P.4    Arock, M.5    Lechner, K.6
  • 31
    • 0034981905 scopus 로고    scopus 로고
    • Utility of flow cytometric analysis of mast cells in the diagnosis and classification of adult mastocytosis
    • Escribano L., Diaz-Agustin B., Bellas C., Navalon R., Nunez R., Sperr W.R., et al. Utility of flow cytometric analysis of mast cells in the diagnosis and classification of adult mastocytosis. Leuk Res 25 7 (2001) 563-570
    • (2001) Leuk Res , vol.25 , Issue.7 , pp. 563-570
    • Escribano, L.1    Diaz-Agustin, B.2    Bellas, C.3    Navalon, R.4    Nunez, R.5    Sperr, W.R.6
  • 32
    • 12144286558 scopus 로고    scopus 로고
    • Immunophenotypic analysis of mast cells in mastocytosis: When and how to do it. Proposals of the Spanish Network on Mastocytosis (REMA)
    • Escribano L., Diaz-Agustin B., Lopez A., Nunez Lopez R., Garcia-Montero A., Almeida J., et al. Immunophenotypic analysis of mast cells in mastocytosis: When and how to do it. Proposals of the Spanish Network on Mastocytosis (REMA). Cytometry B Clin Cytom 58 1 (2004) 1-8
    • (2004) Cytometry B Clin Cytom , vol.58 , Issue.1 , pp. 1-8
    • Escribano, L.1    Diaz-Agustin, B.2    Lopez, A.3    Nunez Lopez, R.4    Garcia-Montero, A.5    Almeida, J.6
  • 33
    • 10744228486 scopus 로고    scopus 로고
    • CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy
    • Pardanani A., Ketterling R.P., Brockman S.R., Flynn H.C., Paternoster S.F., Shearer B.M., et al. CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy. Blood 102 9 (2003) 3093-3096
    • (2003) Blood , vol.102 , Issue.9 , pp. 3093-3096
    • Pardanani, A.1    Ketterling, R.P.2    Brockman, S.R.3    Flynn, H.C.4    Paternoster, S.F.5    Shearer, B.M.6
  • 34
    • 0035042311 scopus 로고    scopus 로고
    • Mastocytosis: recent advances in defining the disease
    • Hartmann K., and Henz B.M. Mastocytosis: recent advances in defining the disease. Br J Dermatol 144 4 (2001) 682-695
    • (2001) Br J Dermatol , vol.144 , Issue.4 , pp. 682-695
    • Hartmann, K.1    Henz, B.M.2
  • 35
    • 33947328520 scopus 로고    scopus 로고
    • Oncogenes in myeloproliferative disorders
    • Tefferi A., and Gilliland D.G. Oncogenes in myeloproliferative disorders. Cell Cycle 6 5 (2007) 550-566
    • (2007) Cell Cycle , vol.6 , Issue.5 , pp. 550-566
    • Tefferi, A.1    Gilliland, D.G.2
  • 36
    • 1542329011 scopus 로고    scopus 로고
    • Systemic mastocytosis
    • Akin C., and Metcalfe D.D. Systemic mastocytosis. Annu Rev Med 55 (2004) 419-432
    • (2004) Annu Rev Med , vol.55 , pp. 419-432
    • Akin, C.1    Metcalfe, D.D.2
  • 37
    • 0036843907 scopus 로고    scopus 로고
    • Systemic mast cell disease without associated hematologic disorder: a combined retrospective and prospective study
    • Pardanani A., Baek J.Y., Li C.Y., Butterfield J.H., and Tefferi A. Systemic mast cell disease without associated hematologic disorder: a combined retrospective and prospective study. Mayo Clin Proc 77 11 (2002) 1169-1175
    • (2002) Mayo Clin Proc , vol.77 , Issue.11 , pp. 1169-1175
    • Pardanani, A.1    Baek, J.Y.2    Li, C.Y.3    Butterfield, J.H.4    Tefferi, A.5
  • 38
    • 34249333084 scopus 로고    scopus 로고
    • Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria
    • Valent P., Akin C., Escribano L., Fodinger M., Hartmann K., Brockow K., et al. Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria. Eur J Clin Invest 37 6 (2007) 435-453
    • (2007) Eur J Clin Invest , vol.37 , Issue.6 , pp. 435-453
    • Valent, P.1    Akin, C.2    Escribano, L.3    Fodinger, M.4    Hartmann, K.5    Brockow, K.6
  • 39
    • 0346154747 scopus 로고    scopus 로고
    • Response to therapy with interferon alpha-2b and prednisolone in aggressive systemic mastocytosis: report of five cases and review of the literature
    • Hauswirth A.W., Simonitsch-Klupp I., Uffmann M., Koller E., Sperr W.R., Lechner K., et al. Response to therapy with interferon alpha-2b and prednisolone in aggressive systemic mastocytosis: report of five cases and review of the literature. Leuk Res 28 3 (2004) 249-257
    • (2004) Leuk Res , vol.28 , Issue.3 , pp. 249-257
    • Hauswirth, A.W.1    Simonitsch-Klupp, I.2    Uffmann, M.3    Koller, E.4    Sperr, W.R.5    Lechner, K.6
  • 40
    • 0036128440 scopus 로고    scopus 로고
    • Osteoporosis and bone marrow mastocytosis: dissociation of skeletal responses and mast cell activity during long-term bisphosphonate therapy
    • Brumsen C., Hamdy N.A., and Papapoulos S.E. Osteoporosis and bone marrow mastocytosis: dissociation of skeletal responses and mast cell activity during long-term bisphosphonate therapy. J Bone Miner Res 17 4 (2002) 567-569
    • (2002) J Bone Miner Res , vol.17 , Issue.4 , pp. 567-569
    • Brumsen, C.1    Hamdy, N.A.2    Papapoulos, S.E.3
  • 41
    • 0036958893 scopus 로고    scopus 로고
    • Mastocytosis: current concepts in diagnosis and treatment
    • Escribano L., Akin C., Castells M., Orfao A., and Metcalfe D.D. Mastocytosis: current concepts in diagnosis and treatment. Ann Hematol 81 12 (2002) 677-690
    • (2002) Ann Hematol , vol.81 , Issue.12 , pp. 677-690
    • Escribano, L.1    Akin, C.2    Castells, M.3    Orfao, A.4    Metcalfe, D.D.5
  • 42
    • 0345772088 scopus 로고    scopus 로고
    • Aggressive systemic mastocytosis and related mast cell disorders: current treatment options and proposed response criteria
    • Valent P., Akin C., Sperr W.R., Escribano L., Arock M., Horny H.P., et al. Aggressive systemic mastocytosis and related mast cell disorders: current treatment options and proposed response criteria. Leuk Res 27 7 (2003) 635-641
    • (2003) Leuk Res , vol.27 , Issue.7 , pp. 635-641
    • Valent, P.1    Akin, C.2    Sperr, W.R.3    Escribano, L.4    Arock, M.5    Horny, H.P.6
  • 46
    • 0344741334 scopus 로고    scopus 로고
    • Treatment of systemic mast cell disease with 2-chlorodeoxyadenosine
    • Pardanani A., Hoffbrand A.V., Butterfield J.H., and Tefferi A. Treatment of systemic mast cell disease with 2-chlorodeoxyadenosine. Leuk Res 28 2 (2004) 127-131
    • (2004) Leuk Res , vol.28 , Issue.2 , pp. 127-131
    • Pardanani, A.1    Hoffbrand, A.V.2    Butterfield, J.H.3    Tefferi, A.4
  • 47
    • 33644897314 scopus 로고    scopus 로고
    • Establishment of a murine model of aggressive systemic mastocytosis/mast cell leukemia
    • Demehri S., Corbin A., Loriaux M., Druker B.J., and Deininger M.W. Establishment of a murine model of aggressive systemic mastocytosis/mast cell leukemia. Exp Hematol 34 3 (2006) 284-288
    • (2006) Exp Hematol , vol.34 , Issue.3 , pp. 284-288
    • Demehri, S.1    Corbin, A.2    Loriaux, M.3    Druker, B.J.4    Deininger, M.W.5
  • 48
    • 0036493872 scopus 로고    scopus 로고
    • The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations
    • Ma Y., Zeng S., Metcalfe D.D., Akin C., Dimitrijevic S., Butterfield J.H., et al. The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations. Blood 99 5 (2002) 1741-1744
    • (2002) Blood , vol.99 , Issue.5 , pp. 1741-1744
    • Ma, Y.1    Zeng, S.2    Metcalfe, D.D.3    Akin, C.4    Dimitrijevic, S.5    Butterfield, J.H.6
  • 49
    • 0026094783 scopus 로고
    • Persistence of systemic mastocytosis after allogeneic bone marrow transplantation in spite of complete remission of the associated myelodysplastic syndrome
    • Ronnov-Jessen D., Lovgreen Nielsen P., and Horn T. Persistence of systemic mastocytosis after allogeneic bone marrow transplantation in spite of complete remission of the associated myelodysplastic syndrome. Bone Marrow Transplant 8 5 (1991) 413-415
    • (1991) Bone Marrow Transplant , vol.8 , Issue.5 , pp. 413-415
    • Ronnov-Jessen, D.1    Lovgreen Nielsen, P.2    Horn, T.3
  • 50
    • 0031084802 scopus 로고    scopus 로고
    • Molecular genetics and development of mast cells: implications for molecular medicine
    • Fodinger M., and Mannhalter C. Molecular genetics and development of mast cells: implications for molecular medicine. Mol Med Today 3 3 (1997) 131-137
    • (1997) Mol Med Today , vol.3 , Issue.3 , pp. 131-137
    • Fodinger, M.1    Mannhalter, C.2
  • 51
    • 0346880065 scopus 로고    scopus 로고
    • Clinical, genetic, and therapeutic insights into systemic mast cell disease
    • Tefferi A., and Pardanani A. Clinical, genetic, and therapeutic insights into systemic mast cell disease. Curr Opin Hematol 11 1 (2004) 58-64
    • (2004) Curr Opin Hematol , vol.11 , Issue.1 , pp. 58-64
    • Tefferi, A.1    Pardanani, A.2
  • 52
    • 31544481378 scopus 로고    scopus 로고
    • OSI-930: a novel selective inhibitor of Kit and kinase insert domain receptor tyrosine kinases with antitumor activity in mouse xenograft models
    • Garton A.J., Crew A.P., Franklin M., Cooke A.R., Wynne G.M., Castaldo L., et al. OSI-930: a novel selective inhibitor of Kit and kinase insert domain receptor tyrosine kinases with antitumor activity in mouse xenograft models. Cancer Res 66 2 (2006) 1015-1024
    • (2006) Cancer Res , vol.66 , Issue.2 , pp. 1015-1024
    • Garton, A.J.1    Crew, A.P.2    Franklin, M.3    Cooke, A.R.4    Wynne, G.M.5    Castaldo, L.6
  • 53
    • 30444446680 scopus 로고    scopus 로고
    • PKC412 inhibits in vitro growth of neoplastic human mast cells expressing the D816V-mutated variant of KIT: comparison with AMN107, imatinib, and cladribine (2CdA) and evaluation of cooperative drug effects
    • Gleixner K.V., Mayerhofer M., Aichberger K.J., Derdak S., Sonneck K., Bohm A., et al. PKC412 inhibits in vitro growth of neoplastic human mast cells expressing the D816V-mutated variant of KIT: comparison with AMN107, imatinib, and cladribine (2CdA) and evaluation of cooperative drug effects. Blood 107 2 (2006) 752-759
    • (2006) Blood , vol.107 , Issue.2 , pp. 752-759
    • Gleixner, K.V.1    Mayerhofer, M.2    Aichberger, K.J.3    Derdak, S.4    Sonneck, K.5    Bohm, A.6
  • 54
    • 27144506215 scopus 로고    scopus 로고
    • Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation
    • Gotlib J., Berube C., Growney J.D., Chen C.C., George T.I., Williams C., et al. Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation. Blood 106 8 (2005) 2865-2870
    • (2005) Blood , vol.106 , Issue.8 , pp. 2865-2870
    • Gotlib, J.1    Berube, C.2    Growney, J.D.3    Chen, C.C.4    George, T.I.5    Williams, C.6
  • 55
    • 9444258068 scopus 로고    scopus 로고
    • Sensitivity of oncogenic KIT mutants to the kinase inhibitors MLN518 and PD180970
    • Corbin A.S., Griswold I.J., La Rosee P., Yee K.W., Heinrich M.C., Reimer C.L., et al. Sensitivity of oncogenic KIT mutants to the kinase inhibitors MLN518 and PD180970. Blood 104 12 (2004) 3754-3757
    • (2004) Blood , vol.104 , Issue.12 , pp. 3754-3757
    • Corbin, A.S.1    Griswold, I.J.2    La Rosee, P.3    Yee, K.W.4    Heinrich, M.C.5    Reimer, C.L.6
  • 56
    • 15244341289 scopus 로고    scopus 로고
    • A novel NF-kappaB inhibitor, IMD-0354, suppresses neoplastic proliferation of human mast cells with constitutively activated c-kit receptors
    • Tanaka A., Konno M., Muto S., Kambe N., Morii E., Nakahata T., et al. A novel NF-kappaB inhibitor, IMD-0354, suppresses neoplastic proliferation of human mast cells with constitutively activated c-kit receptors. Blood 105 6 (2005) 2324-2331
    • (2005) Blood , vol.105 , Issue.6 , pp. 2324-2331
    • Tanaka, A.1    Konno, M.2    Muto, S.3    Kambe, N.4    Morii, E.5    Nakahata, T.6
  • 59
    • 38549127753 scopus 로고    scopus 로고
    • How we diagnose and treat WHO-defined systemic mastocytosis in adults
    • Tefferi A., Verstovsek S., and Pardanani A. How we diagnose and treat WHO-defined systemic mastocytosis in adults. Haematologica 93 1 (2008) 6-9
    • (2008) Haematologica , vol.93 , Issue.1 , pp. 6-9
    • Tefferi, A.1    Verstovsek, S.2    Pardanani, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.