Capsid modification of adeno-associated virus and tumor targeting gene therapy

Chinese Science Bulletin

Volumn 53, Issue 24, 2008, Pages 3790-3797

  Xu, Zenghui ^a   Zhou, Xiumei ^a   Shi, Wenfang ^a,b   Qian, Qijun ^a  

^a ZHEJIANG SCI TECH UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Gene therapy; RAAV; Target therapy

Indexed keywords

ADENO-ASSOCIATED VIRUS; MIRIDAE;

EID: 57849100478     PISSN: 10016538     EISSN: 18619541     Source Type: Journal    
DOI: 10.1007/s11434-008-0487-y     Document Type: Article

References (52)

1. J. E. Rabinowitz W. Xiao R. J. Samulski 1999 Insertional mutagenesis of AAV2 capsid and the production of recombinant virus Virology 265 2 274 285
2. D. E. Bowles J. E. Rabinowitz R. J. Samulski 2003 Marker rescue of adeno-associated virus (AAV) capsid mutants: A novel approach for chimeric AAV production J Virol 77 1 423 432
3. L. Perabo H. Buning D. M. Kofler 2003 In vitro selection of viral vectors with modified tropism: The adeno-associated virus display Mol Ther 8 1 151 157
4. O. J. Muller F. Kaul M. D. Weitzman 2003 Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors Nat Biotechnol 21 9 1040 1046
5. N. Maheshri J. T. Koerber B. K. Kaspar 2006 Directed evolution of adeno-associated virus yields enhanced gene delivery vectors Nat Biotechnol 24 2 198 204
6. A. Hajitou M. Trepel C. E. Lilley 2006 A hybrid vector for ligand-directed tumor targeting and molecular imaging Cell 125 2 385 398
7. G. Gao L. H. Vandenberghe M. R. Alvira 2004 Clades of Adeno-associated viruses are widely disseminated in human tissues J Virol 78 12 6381 6388
8. S. Mori L. Wang T. Takeuchi 2004 Two novel adeno-associated viruses from cynomolgus monkey: Pseudotyping characterization of capsid protein Virology 330 2 375 383
9. M. Schmidt E. Grot P. Cervenka 2006 Identification and characterization of novel adeno-associated virus isolates in ATCC virus stocks J Virol 80 10 5082 5085
10. C. Summerford R. J. Samulski 1998 Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions J Virol 72 2 1438 1445
11. J. S. Bartlett J. Kleinschmidt R. C. Boucher 1999 Targeted adeno-associated virus vector transduction of nonpermissive cells mediated by a bispecific F(ab'gamma) 2 antibody Nat Biotechnol 17 2 181 186
12. H. Buning M. U. Ried L. Perabo 2003 Receptor targeting of adeno-associated virus vectors Gene Ther 10 14 1142 1151
13. S. Ponnazhagan G. Mahendra S. Kumar 2002 Conjugate-based targeting of recombinant adeno-associated virus type 2 vectors by using avidin-linked ligands J Virol 76 24 12900 12907
14. G. S. Arnold A. K. Sasser M. D. Stachler 2006 Metabolic biotinylation provides a unique platform for the purification and targeting of multiple AAV vector serotypes Mol Ther 14 1 97 106
15. H. Romanczuk C. E. Galer J. Zabner 1999 Modification of an adenoviral vector with biologically selected peptides: A novel strategy for gene delivery to cells of choice Hum Gene Ther 10 16 2615 2626
16. G. K. Lee N. Maheshri B. Kaspar 2005 PEG conjugation moderately protects adeno-associated viral vectors against antibody neutralization Biotechnol Bioeng 92 1 24 34
17. H. T. Le Q. C. Yu J. M. Wilson 2005 Utility of PEGylated recombinant adeno-associated viruses for gene transfer J Control Rel 108 1 161 177
18. A. Girod M. Ried C. Wobus 1999 Genetic capsid modifications allow efficient re-targeting of adeno-associated virus type 2 Nat Med 5 9 1052 1056
19. M. Grifman M. Trepel P. Speece 2001 Incorporation of tumor-targeting peptides into recombinant adeno-associated virus capsids Mol Ther 3 6 964 975
20. Q. Yang M. Mamounas G. Yu 1998 Development of novel cell surface CD34-targeted recombinant adeno-associated virus vectors for gene therapy Hum Gene Ther 9 13 1929 1937
21. P. Wu W. Xiao T. Conlon 2000 Mutational analysis of the adeno-associated virus type 2 (AAV2) capsid gene and construction of AAV2 vectors with altered tropism J Virol 74 18 8635 8647
22. W. S. Weichert J. S. Parker A. T. Wahid 1998 Assaying for structural variation in the parvovirus capsid and its role in infection Virology 250 1 106 117
23. M. S. Chapman M. G. Rossmann 1993 Structure, sequence, and function correlations among parvoviruses Virology 194 2 491 508
24. W. Shi G. S. Arnold J. S. Bartlett 2001 Insertional mutagenesis of the adeno-associated virus type 2 (AAV2) capsid gene and generation of AAV2 vectors targeted to alternative cell-surface receptors Hum Gene Ther 12 14 1697 1711
25. W. Shi A. Hemminki J. S. Bartlett 2006 Capsid modifications overcome low heterogeneous expression of heparan sulfate proteoglycan that limits AAV2-mediated gene transfer and therapeutic efficacy in human ovarian carcinoma Gynecol Oncol 103 3 1054 1062
26. M. U. Ried A. Girod K. Leike 2002 Adeno-associated virus capsids displaying immunoglobulin-binding domains permit antibody-mediated vector retargeting to specific cell surface receptors J Virol 76 9 4559 4566
27. B. Hauck W. Xiao 2003 Characterization of tissue tropism determinants of adeno-associated virus type 1 J Virol 77 4 2768 2774
28. L. Perabo A. Huber S. Märsch 2008 Artificial evolution with adeno-associated viral libraries Comb Chem High Throughput Screen 11 2 118 126
29. B. Hauck L. Chen W. Xiao 2003 Generation and characterization of chimeric recombinant AAV vectors Mol Ther 7 3 419 425
30. B. L. Davidson C. S. Stein J. A. Heth 2000 Recombinant adeno-associated virus type 2, 4, and 5 vectors: Transduction of variant cell types and regions in the mammalian central nervous system Proc Natl Acad Sci USA 97 7 3428 3432
31. H. Chao Y. Liu J. Rabinowitz 2000 Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors Mol Ther 2 6 619 623
32. J. M. Alisky S. M. Hughes S. L. Sauter 2000 Transduction of murine cerebellar neurons with recombinant FIV and AAV5 vectors Neuroreport 11 12 2669 2673
33. M. J. Blankinship P. Gregorevic J. M. Allen 2004 Efficient transduction of skeletal muscle using vectors based on adeno-associated virus serotype 6 Mol Ther 10 4 671 678
34. G. P. Gao M. R. Alvira L. Wang 2002 Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy Proc Natl Acad Sci USA 99 18 11854 11859
35. C. A. Pacak C. S. Mah B. D. Thattaliyath 2006 Recombinant adeno-associated virus serotype 9 leads to preferential cardiac transduction in vivo Circ Res 99 4 e3 9
36. S. Mori T. Takeuchi Y. Enomoto 2006 Biodistribution of a low dose of intravenously administered AAV-2, 10, and 11 vectors to cynomolgus monkeys Jpn J Infect Dis 59 5 285 293
37. G. P. Smith 1985 Filamentous fusion phage: Novel expression vectors that display cloned antigens on the virion surface Science 228 4705 1315 1317
38. R. Cortese P. Monaci A. Luzzago 1996 Selection of biologically active peptides by phage display of random peptide libraries Curr Opin Biotechnol 7 6 616 621
39. R. Pasqualini E. Ruoslahti 1996 Organ targeting in vivo using phage display peptide libraries Nature 380 6572 364 366
40. S. A. Nicklin H. Buening K. L. Dishart 2001 Efficient and selective AAV2-mediated gene transfer directed to human vascular endothelial cells Mol Ther 4 3 174 181
41. L. Perabo D. Goldnau K. White 2006 Heparan sulfate proteoglycan binding properties of adeno-associated virus retargeting mutants and consequences for their in vivo tropism J Virol 80 14 7265 7269
42. L. M. Work H. Buning E. Hunt 2006 Vascular bed-targeted in vivo gene delivery using tropism-modified adeno-associated viruses Mol Ther 13 4 683 693
43. A. Rothe R. J. Hosse B. E. Power 2006 In vitro display technologies reveal novel biopharmaceutics Faseb J 20 10 1599 1610
44. H. R. Hoogenboom 2005 Selecting and screening recombinant antibody libraries Nat Biotechnol 23 9 1105 1116
45. L. Yuan I. Kurek J. English 2005 Laboratory-directed protein evolution Microbiol Mol Biol Rev 69 3 373 392
46. K. Bupp A. Sarangi M. J. Roth 2006 Selection of feline leukemia virus envelope proteins from a library by functional association with a murine leukemia virus envelope Virology 351 2 340 348
47. J. H. Yu D. V. Schaffer 2006 High-throughput, library-based selection of a murine leukemia virus variant to infect nondividing cells J Virol 80 18 8981 8988
48. Z. J. Wu X. B. Wu H. Cao 2002 A novel and highly efficient production system for recombinant adeno-associated virus vector Sci China Ser C-Life Sci 45 96 104
49. Z. W. Cao Y. Lin L. Q. Cheng 2008 Influence of defect ITR on the packaging and infectivity of AAV Prog Biochem Biophys 35 2 224 230
50. Q. Xie W. Bu S. Bhatia 2002 The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy Proc Natl Acad Sci USA 99 16 10405 10410
51. H. J. Nam M. D. Lane E. Padron 2007 Structure of adeno-associated virus serotype 8, a gene therapy vector J Virol 81 22 12260 12271
52. A. Hajitou D. C. Lev J. A. Hannay 2008 A preclinical model for predicting drug response in soft-tissue sarcoma with targeted AAVP molecular imaging Proc Natl Acad Sci USA 105 11 4471 4476