Porotic lesions in immature skeletons from Stara Torina, Late Medieval Serbia

International Journal of Osteoarchaeology

Volumn 18, Issue 5, 2008, Pages 458-475

  Djuric, M ^a   Milovanovic, P ^a   Janovic, A ^a   Draskovic, M ^a   Djukic, K ^a   Milenkovic, P ^a  

^a UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

Anaemia; Cribra orbitalia; Femoral cribra; Humeral cribra; Infection; Porotic hyperostosis

Indexed keywords

EID: 57849099212     PISSN: 1047482X     EISSN: 10991212     Source Type: Journal    
DOI: 10.1002/oa.955     Document Type: Article

References (145)

1. Andrews CL. 2000. Evaluation of the marrow space in the adult hip. Radiographics 20: S27-S42.
2. Angel JL. 1966. Porotic hyperostosis, anaemias, malarias and marshes in the prehistoric eastern Mediterranean. Science 153: 760-763.
3. Angel JL. 1971. Lerna: A Preclassical Site in the Argolid, Volume II - The People. Smithsonian Institution Press: Washington, DC.
4. Angel JL. 1972. Ecology and population in the Eastern Mediterranean. World Archaeology 4: 88-105.
5. Armelagos GJ, Goodman AH. 1991. The concept of stress and its relevance to studies of adaptation in prehistoric populations. Collegium Antropologicum 15: 45-58.
6. Arnett TR, Gibbons DC, Utting JC, Orriss IR, Hoebertz A, Rosendaal M, Meghji S. 2003. Hypoxia is a major stimulator of osteoclast formation and bone resorption. Journal of Cell Physiology 196: 2-8.
7. Babic S. 1996. Madarska civilizacija. Geopoetika: Beograd.
8. Bartha A. 1975. Hungarian Society in the 9th and 10th Centuries. Akademiai Kiado: Budapest.
9. Baynes RD, Bothwell TH. 1990. Iron deficiency. Annual Review of Nutrition 10: 133-148.
10. Bennike P, Lewis ME, Schutkowski H, Valentin F. 2005. Comparison of child morbidity in two contrasting medieval cemeteries from Denmark. American Journal of Physical Anthropology 128: 734-746.
11. Brothwell D. 1981. Digging Up Bones. British Museum, Oxford University Press: Oxford.
12. Carlson DS, Armelagos GJ, Van Gerven DP. 1974. Factors influencing the etiology of cribra orbitalia in prehistoric Nubia. Journal of Human Evolution 3: 405-410.
13. Cazzola M, Pootrakul P, Huebers HA, Eng M, Eschbach J, Finch CA. 1987. Erythroid marrow function in anemic man. Blood 69: 296-301.
14. Cesari M, Pahor M, Lauretani F, Penninx B, Bartali B, Russo R, Cherubini A, Woodman R, Bandinelli S, Guralnik J, Ferrucci L. 2005. Bone density and hemoglobin levels in older persons: results from the InCHIANTI study. Osteoporosis International 16: 691-699.
15. Chundun Z, Roberts CA. 1995. Human skeletal remains. In Excavation of the Hospital of St Giles by Brompton Bridge, North Yorkshire, Cardwell P (ed.). Archaeological Journal 152: 214-220.
16. Cohen MN, Armelagos GJ. 1984. Paleopathology at the Origins of Agriculture. Academic Press: New York.
17. Cornero S, Puche RC. 2002. Cribra orbitalia (hiperostosis porótica) en una población prehistórica del Paraná medio. Medicina (Buenos Aires) 62: 169-172.
18. Cox N, Hinkle R. 2002. Infant botulism. American Family Physician 65: 1388-1392.
19. Cybulski JS. 1977. Cribra orbitalia, a possible sign of anaemia in early historic native populations of the British Columbia coast. American Journal of Physical Anthropology 47: 31-40.
20. Dale JM. 1994. Cribra Orbitalia, Nutrition and Pathogenic Stress in prehistoric skeletal remains from the Pender Island Canal Sites (DeRt1, DeRT2), British Columbia, Canada. MSc thesis, Simon Fraser University.
21. Deicher R, Horl WH. 2006. New insights into the regulation of iron homeostasis. European Journal of Clinical Investigation 36: 301-309.
22. Di Stefano M, Chiabotto P, Roggia C, Garofalo F, Lala R, Piga A, Isaia GC. 2004. Bone mass and metabolism in thalassemic children and adolescents treated with different iron-chelating drugs. Journal of Bone Mineral Metabolism 22: 53-57.
23. Djuric MP, Roberts CA, Rakocevic ZB, Djonic DD, Lesic AR. 2006. Fractures in late medieval skeletal populations from Serbia. American Journal of Physical Anthropology 130: 167-178.
24. Djuric-Srejic M. 1990. Antropološke, morfološke i paleopatološke karakteristike srednjovekovnog stanovništva iz dve nekropole u Zapadnoj Srbiji. PhD thesis, University of Novi Sad.
25. Djuric-Srejic M, Zivanovic S, Letic V. 1992. Paleopathological evidence in skeletons of medieval Serbian population. Rivista di Antropologia (Roma) 70: 153-157.
26. Djuric-Srejic M, Roberts C. 2001. Palaeopathological evidence of infectious disease in skeletal populations from later medieval Serbia. International Journal of Osteoarchaeology 11: 311-320.
27. El-Najjar MY. 1976. Maize, malaria and the anaemias in the pre-Columbian New World. Yearbook of Physical Anthropology 20: 329-337.
28. El-Najjar MY, Lozoff B, Ryan DJ. 1975. The paleoepidemiology of porotic hyperostosis in the American Southwest: radiological and ecological considerations. American Journal of Roentgenology, Radium Therapy and Nuclear Medicine 125: 918-924.
29. El-Najjar M, Robertson A Jr. 1976. Spongy bones in prehistoric America. Science 193: 141-143.
30. El-Najjar MY, Ryan DJ, Turner CG, Lozoff B. 1976. The etiology of porotic hyperostosis among the prehistoric and historic Anasazi Indians of Southwestern United States. American Journal of Physical Anthropology 44: 477-488.
31. El-Najjar MY, Andrews J, Moore JG, Bragg DG. 1982. Iron deficiency anaemia in two prehistoric American Indian skeletons: a dietary hypothesis. Plains Anthropologist 27: 205-210.
32. Facchini F, Rastelli E, Brasili P. 2004. Cribra orbitalia and cribra cranii in Roman skeletal remains from the Ravenna area and Rimini (I-IV century AD). International Journal of Osteoarchaeology 14: 126-136.
33. Fairgrieve SI, Molto JE. 2000. Cribra orbitalia in two temporally disjunct population samples from the Dakhlen Oasis, Egypt. American Journal of Physical Anthropology 111: 319-331.
34. Fornaciari G, Mallegini F, Bertini D, Nutti V. 1982. Cribra orbitalia and elemental bone iron in the Punics of Carthage. Ossa 8: 63-77.
35. Fugedi E. 1986. Castle and Society in Medieval Hungary 1000-1437. Akademiai Kiado: Budapest.
36. Fujimoto H, Fujimoto K, Ueda A, Ohata M. 1999. Hypoxemia is a risk factor for bone mass loss. Journal of Bone and Mineral Metabolism 17: 211-216.
37. Ganz T. 2003. Hepcidin, a key regulator of iron metabolism and mediator of anaemia of inflammation. Blood 102: 783-788.
38. Gilbert R, Mielke J (eds). 1985. The Analysis of Prehistoric Diets. Academic Press: New York.
39. Goodman AH, Martin DL, Armelagos GJ, Clark G. 1984. Indications of stress from bone and teeth. In Paleopathology and the Origins of Agriculture, Cohen MN, Armelagos GJ (eds). Academic Press: New York; 13-49.
40. Goodman AH, Thomas RB, Swedlund AC, Armelagos GJ. 1988. Biocultural perspectives on stress in prehistoric, historical, and contemporary population research. Yearbook of Physical Anthropology 31: 169-202.
41. Grauer AL. 1993. Patterns of anaemia and infection from medieval York, England. American Journal of Physical Anthropology 91: 203-213.
42. Guidotti A. 1984. Frequencies of cribra orbitalia in central Italy (19th century) under special consideration of their degrees of expression. Anthropologische Anzeiger 42: 11-16.
43. Hengen OP. 1971. Cribra orbitalia: pathogenesis and probable etiology. Homo 22: 57-76.
44. Hill MC, Armelagos GJ. 1990. Porotic hyperostosis in past and present perspective. In A Life in Science: Papers in Honor of J. Lawrence Angel, Buikstra JE (ed.). Center for American Archeology Scientific Papers No. 6; 52-63.
45. Hirata K. 1990. Secular trend and age distribution of cribra orbitalia in Japanese. Human Evolution 5: 375-385.
46. Hishikawa K, Iwai K. 2005. Recent advance in the understanding of iron metabolism and its role on host defense. Japanese Journal of Clinical Immunology 28: 372-380.
47. Hodges DC. 1987. Health and agricultural intensification in the prehistoric Valley of Oaxaca, Mexico. American Journal of Physical Anthropology 73: 323-332.
48. Holland TD, O'Brien MJ. 1997. Parasites, porotic hyperostosis and the implications of changing perspectives. American Antiquity 62: 183-193.
49. Hosovski E. 1995. Patološki profil srednjovekovnih stanovnika Mileševa. Prilozi iz Istorijske Antropologije 12: 33-42.
50. Hrdlicka A. 1914. Anthropological work in Peru in 1913, with notes on the pathology of the ancient Peruvians. Smithsonian Miscellaneous Collection 61: 1-69.
51. Huss-Ashmore R, Goodman AH, Armelagos GJ. 1982. Nutritional inference from paleopathology. In Advances in Archaeological Method and Theory, Schiffer MB (ed.). Academic Press: New York; 395-474.
52. Jankauskas J. 1995. Anthropoecology of the late medieval Alytus (data on the 14-17c.c. burial-ground). Lietuvos Archeologija 11: 34-45.
53. Janovic A, Milovanovic P, Djukic K, Milenkovic P, Djuric M. 2006. Juvenile pathology in skeletal remains from Stara Torina. 15th Congress of the European Anthropological Association: 'Man and Environment: Trends and Challenges in Anthropology', Budapest, Abstract Book p. 101.
54. Keenleyside A, Panayotova K. 2006. Cribra orbitalia and porotic hyperostosis in a Greek colonial population (5th to 3rd centuries BC) from the Black Sea. International Journal of Osteoarchaeology 16: 373-384.
55. Kent S. 1986. The influence of sedentism and aggregation on porotic hyperostosis and anaemia: a case study. Man 21: 605-636.
56. Kent S, Dunn D. 1996. Anaemia and the transition of nomadic hunter-gatherers to a sedentary life-style: follow-up study of a Kalahari community. American Journal of Physical Anthropology 99: 455-472.
57. Kiraly B. 1969. Hungary in the Late Eighteenth Century. Columbia University Press: New York.
58. Klepinger LK. 1992. Innovative approaches to the study of past human health and subsistence strategies. In Skeletal Biology of Past Peoples; Research Methods, Saunders SR, Katzenberg MA (eds). Wiley-Liss: New York; 121-130.
59. Kozak J, Krenz-Niedbala M. 2002. The occurrence of cribra orbitalia and its association with enamel hypoplasia in a medieval population from Kolobrzeg, Poland. Variability and Evolution 10: 75-82.
60. Krause A, Neitz S, Magert HJ, et al. 2000. LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity. FEBS Letters 480: 147-150.
61. Lallo JW, Armelagos GJ, Mensforth RP. 1977. The role of diet, disease, and physiology in the origin of porotic hyperostosis. Human Biology 49: 471-483.
62. Larsen CS. 1997. Bioarchaelogy. Interpreting Behaviour from the Human Skeleton. Cambridge University Press: Cambridge.
63. Lewis M, Roberts C. 1997. Growing pains: the interpretation of stress indicators. International Journal of Osteoarchaeology 7: 581-586.
64. Loevnera LA, Tobeyb JD, Yousema DM, Sonnersc AI, Hsua WC. 2002. MR imaging characteristics of cranial bone marrow in adult patients with underlying systemic disorders compared with healthy control subjects. American Journal of Neuroradiology 23: 248-254.
65. Lovrincevic A, Mikic Z. 1989. Atlas osteopatološkib promjena na istorijskim populacijama Jugoslavije. Svjetlost: Sarajevo.
66. Mahachoklertwattana P, Pootrakul P, Chuansumrit A, Choubtum L, Sriphrapradang A, Sirisriro R, Rajatanavin R. 2006. Association between bone mineral density and erythropoiesis in Thai children and adolescents with thalassemia syndromes. Journal of Bone Mineral Metabolism 24: 146-152.
67. Malhorta KC. 1990. Changing patterns of disease in India with special reference to childhood mortality. In Disease in Populations in Transition. Anthropological and Epidemiological Perspectives, Swedlung A, Armelagos G (eds). Bergin and Garvey: London; 313-332.
68. Maresh MM. 1955. Linear growth of the long bones of extremities from infancy through adolescence. American Journal of Diseases of Children 89: 725-742.
69. Maresh MM. 1970. Measurements from roentgenograms, heart size, long bone lengths, bone, muscles and fat widths, skeletal maturation. In Human Growth and Development, McCammon RW (ed.). Charles C. Thomas: Springfield; 155-200.
70. Means RT Jr. 2004. Hepcidin and anaemia. Blood Reviews 18: 219-225.
71. Medeiros DM, Ilich J, Ireton J, Matkovic V, Shiry L, Wildman R. 1997. Femurs from rats fed diets deficient in copper or iron have decreased mechanical strength and altered mineral composition. Journal of Trace Elements in Experimental Medicine 10: 197-203.
72. Medeiros DM, Plattner A, Jennings D, Stoecker B. 2002. Bone morphology, strength and density are compromised in iron-deficient rats and exacerbated by calcium-restriction. Journal of Nutrition 132: 3135-3141.
73. Mensforth R, Lovejoy C, Armelagos G. 1978. The role of constitutional factors, diet, and infectious disease in the etiology of porotic hyperostosis and periosteal reactions in prehistoric infants and children. Medical Anthropology 2: 1-59.
74. Miller RG, Segal JB, Ashar BH, Leung S, Ahmed S, Siddique S, Rice T, Lanzkron S. 2006. High prevalence and correlates of low bone mineral density in young adults with sickle cell disease. American Journal of Hematology 81: 236-241.
75. Miquel-Feucht MJ, Polo-Cerdá M, Villalaín-Blanco JD. 1999a. El síndrome criboso: criba femoral vs criba orbitaria. In Sistematización metodológica en Paleopatología, Actas V Congreso Nacional AEP, Sánchez JA (ed.). Asociación Española de Paleopatología, Alcalá la Real: Jaén, Spain; 221-237.
76. Miquel-Feucht MJ, Polo-Cerdá M, Villalaín -Blanco JD. 1999b. Anthropological and paleopathological studies of a mass execution during the War of Independence in Valencia, Spain (1808-1812). Journal of Paleopathology 11 (3): 15-23.
77. Miquel-Feucht MJ, Polo-Cerdá M, Villalaín-Blanco JD. 1999c. Cribra orbitalia vs. cribra femora: new contributions to the cribose syndrome. Journal of Paleopathology 11: 84.
78. Mittler DM, Van Gerven DP. 1994. Developmental, diachronic and demographic analysis of cribra orbitalia in the Medieval Christian populations of Kulubnarti. American Journal of Physical Anthropology 93: 287-297.
79. Moore SG, Dawson KL. 1990. Red and yellow marrow in the femur: age-related changes in appearance at MR imaging. Radiology 175: 219-223.
80. Nathan H, Haas N. 1966. Cribra orbitalia. Israel Journal of Medical Sciences 2: 170-179.
81. Nemeth E, Ganz T. 2006. Regulation of iron metabolism by hepcidin. Annual Review of Nutrition 26: 323-342.
82. Nicolas G, Chauvet C, Viatte L. 2002. The gene encoding the iron regulatory peptide hepcidin is regulated by anaemia, hypoxia, and inflammation. Journal of Clinical Investigation 110: 1037-1044.
83. Ortner D, Putschar W. 1981. Identification of Pathological Conditions in Human Skeletal Remains. Smithsonian Contributions to Anthropology, No. 28. Smithsonian Institution Press: Washington D.C.
84. Palkovich A. 1980. Pueblo Population and Society: the Arroyo Hondo Skeletal and Mortuary Remains, Arroyo Hondo Archaeological Series 3, School of American Research Press: Santa Fe.
85. Palkovich AM. 1987. Endemic disease patterns in paleopathology: porotic hyperostosis. American Journal of Physical Anthropology 74: 527-537.
86. Park CH, Valore EV, Waring AJ, Ganz T. 2001. Hepcidin, a urinary antimicrobial peptide synthesized in the liver. Journal of Biological Chemistry 276: 7806-7810.
87. Park JH, Park BH, Kim HK, Park TS, Baek HS. 2002. Hypoxia decreases Runx2/Cbfa1 expression in human osteoblast-like cells. Molecular and Cellular Endocrinology 192: 197-203.
88. Pietrangelo A, Trautwein C. 2004. Mechanisms of disease: the role of hepcidin in iron homeostasis - implications for hemochromatosis and other disorders. Nature Clinical Practice Gastroenterology and Hepatology 1: 39-45.
89. Pigeon C, Ilyin G, Courselaud B, et al. 2001. A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. Journal of Biological Chemistry 276: 7811-7819.
90. Piontek J, Kozlowski T. 2002. Frequency of cribra orbitalia in the subadult medieval population from Gruczno, Poland. International Journal of Osteoarchaeology 12: 202-208.
91. Polo-Cerdá M, Miquel-Feucht M, Villalaín-Blanco JD. 1999a. Un modelo experimental de cribra orbitalia: estudio preliminar. In Sistematización metodológica en Paleopatología, Actas V Congreso Nacional AEP, Sánchez JA (ed.). Asociación Española de Paleopatología, Alcalá la Real: Jaén, Spain; 201-212.
92. Polo-Cerdá M, Miquel-Feucht M, Villalaín-Blanco JD. 1999b. Experimental cribra orbitalia in Wistar rats: an etiopathogenic model of porotic hyperostosis and other porotic phenomens. Journal of Paleopathology 11: 95.
93. Polo-Cerdá M, Miquel-Feucht M, Villalaín-Blanco JD. 2000. Indicadores de salud paleonutricional: revisión bibliográfica y nuevas aportaciones. In Actas do 3. Congresso de Arqueologia Peninsular, Vila Real, Portugal, Vol. IX: Contributos das Ciencias e das Tecnologias para a Arqueologia da Peninsula Iberica, Oliveira JV (ed.). Associacção para o Desenvolvimento da Cooperação em Arqueologia: Peninsular Porto; 381-390.
94. Ponec DJ, Resnick D. 1984. On the etiology and pathogenesis of porotic hyperostosis of the skull. Investigative Radiology 19: 313-317.
95. Pootrakul P, Hungspringes S, Fucharoen S, Baylink D, Thompson E, English E, Lee M, Burnell J, Finch C. 1981. Relation between erythropoiesis and bone metabolism and thalassemia. New England Journal of Medicine 304: 1470-1473.
96. Popovic D. 1990. Srbi u Vojvodini. I-III. Matica Srpska: Novi Sad.
97. Rains MJ, Hall DW. 1997. Excavations in St Andrews 1980-1989. A Decade ofWork in a Historic Scottish Burgh. Tayside and Fife Archaeological Committee, Monograph 1, Glenrothes.
98. Rauch F, Neu C, Manz F, Schoenau E. 2001. The development of metaphyseal cortex - implications for distal radius fractures during growth. Journal of Bone and Mineral Research 16: 1547-1555.
99. Ravaglioli A, Krajewski A, Celotti GC, Piancastelli A, Bacchini B, Montanari L, Zama G, Piombi L. 1996. Mineral evolution of bone. Biomaterials 17: 617-622.
100. Ribot I, Roberts C. 1996. A study of non-specific stress indicators and skeletal growth in two mediaeval subadult populations. Journal of Archaeological Science 23: 67-79.
101. Ricci R, Mancinelli D, Vargiu R, Cucina A, Santandrea E, Capelli A, Catalano P. 1997. Pattern of porotic hyperostosis and quality of life in a II century AD farm near Rome. Rivista di Antropologia (Roma) 75: 117-128.
102. Roberts C, Manchester K. 1997. The Archaeology of Disease. Sutton Publishing: Gloucester.
103. Roberts C, Cox M. 2003. Health and Disease in Britain: From Prehistory to the Present Day. Sutton Publishing: Gloucester.
104. Robledo B, Trancho GJ, Brothwell D. 1995. Cribra orbitalia: health indicator in the late Roman population of Cannington (Somerset, Great Britain). Journal of Paleopathology 7: 185-193.
105. Rothschild BM. 2000. Porotic hyperostosis as a manifestation of iron deficiency? Chungara, Revista de Antropologia Chilena 32: 85-87.
106. Rothschild BM, Ruhli FJ, Sebes J, Naples V, Billard M. 2004. Relationship between porotic hyperostosis and cribra orbitalia? PALEOBIOS 13. Available at: http://anthropologie-et-paleopathologie.univ-lyon1.fr/ html/html/Paleobios.htm.
107. Rude RK. 1998. Magnesium deficiency induces bone loss in the rat. Mineral and Electrolyte Metabolism 24: 314-320.
108. Ryan DJ. 1977. The paleopathology and paleoepidemiology of the Kayenta Anasazi Indians in Northwestern Arizona. PhD thesis, Arizona State University, Tempe.
109. Salvadei L, Ricci F, Manzi G. 2001. Porotic hyperostosis as a marker of health and nutritional conditions during childhood: studies at the transition between Imperial Rome and the early Middle Ages. American Journal of Human Biology 13: 709-717.
110. Sandstead HH. 1992. Fiber, phytates, and mineral nutrition. Nutrition Review 50: 30-31.
111. Scheuer JL, Black SM. 2000. Developmental Juvenile Osteology. Academic Press: London.
112. Schultz M. 2001. Paleohistopathology of bone: a new approach to the study of ancient diseases. Yearbook of Physical Anthropology 44: 106-147.
113. Seeman E. 2004. The growth and age-related origins of bone fragility in men. Calcified Tissue International 75: 100-109.
114. Steinbock RT. 1976. Paleopathological Diagnosis and Interpretation. Charles C. Thomas: Springfield, IL.
115. Stuart-Macadam P. 1982. A correlative study of a palaeopathology of the skull. PhD thesis, University of Cambridge.
116. Stuart-Macadam P. 1985. Porotic hyperostosis: representative of a childhood condition. American Journal of Physical Anthropology 66: 391-398.
117. Stuart-Macadam P. 1987a. A radiographic study of porotic hyperostosis. American Journal of Physical Anthropology 74: 511-520.
118. Stuart-Macadam P. 1987b. Porotic hyperostosis: new evidence to support the anaemia theory. American Journal of Physical Anthropology 74: 521-526.
119. Stuart-Macadam P. 1989. Porotic hyperostosis: relationship between orbital and vault lesions. American Journal of Physical Anthropology 80: 187-193.
120. Stuart-Macadam P. 1991. Anaemia in Roman Britain: Poundbury Camp. In Health in Past Societies. Biocultural Interpretations of Human Skeletal Remains in Archaeological Contexts, Bush H, Zvelebil M (eds). BAR International Series 567: Oxford; 101-113.
121. Stuart-Macadam P. 1992. Porotic hyperostosis: a new perspective. American Journal of Physical Anthropology 87: 39-47.
122. Stuart-Macadam P, Kent S. 1992. Diet, Demography and Disease. Changing Perspectives on Anaemia. Walter de Gruyter: New York.
123. Sullivan A. 2005. Prevalence and etiology of acquired anaemia in Medieval York, England. American Journal of Physical Anthropology 128: 252-272.
124. Tannahill R. 1989. Food in History. Three Rivers Press: New York.
125. Tayles N. 1996. Anaemia, genetic diseases, and malaria in prehistoric mainland Southeast Asia. American Journal of Physical Anthropology 101: 11-27.
126. Tubbs RM, O'Gorman J. 2005. Assessing Oneota diet and health: a community and lifeway perspective. Midcontinental Journal of Archaeology 30: 119-163.
127. Turbón D, Botella M, Campillo D, Hernández M, Jiménez S, Péréz-Péréz A, Pons J, Du Souich P, Trancho G. 1991/92. Diet and stress,arkers in past Spanish populations. Journal of Human Ecology 2(3)/3(1): 271-280.
128. Ubelaker D. 1978. Human Skeletal Remains; Excavation, Analysis, Interpretation. Aldine: Chicago.
129. Ubelaker D. 1984. Prehistoric human biology of Ecuador: possible temporal trends and cultural correlations. In Paleopathology at the Origins of Agriculture, Cohen MN, Armelagos GJ (eds). Academic Press: New York; 491-513.
130. Utting JC, Robins SP, Brandao-Burch A, Orriss IR, Behar J, Arnett TR. 2006. Hypoxia inhibits the growth, differentiation and bone-forming capacity of rat osteoblasts. Experimental Cell Research 312: 1693-1702.
131. Vande Berg BC, Malghem J, Lecouvet FE, Maldague B. 1998. Magnetic resonance imaging of the normal bone marrow. Skeletal Radiology 27: 471-483.
132. Waitches G, Zawin JK, Poznanski AK. 1994. Sequence and rate of bone marrow conversion in the femora of children as seen on MR imaging: are accepted standards accurate? American Journal of Roentgenology 162: 1399-1406.
133. Walker P. 1986. Porotic hyperostosis in marinedependent California Indian population. American Journal of Physical Anthropology 69: 345-354.
134. Wapler U, Crubezy E, Schultz M. 2004. Is cribra orbitalia synonymous with anaemia? Analysis and interpretation of cranial pathology in Sudan. American Journal of Physical Anthropology 123: 333-339.
135. Weinberg ED. 1992. Iron withholding in prevention of disease. In Diet, Demography and Disease Changing Patterns on Anaemia, Stuart-Macadam P, Kent S (eds). Aldine de Gruyter: New York; 105-150.
136. Weiss G, Goodnough LT. 2005. Anaemia of chronic disease. New England Journal of Medicine 352: 1011-1023.
137. Welcker H. 1888. Cribra orbitalia. Archaeological Anthropology 17: 1-16.
138. Wiggins R. 1991. Porotic hyperostosis, cribra orbitalia, enamel hypoplasia, periosteal reaction and metopism: a correlation of their prevalence and an assessment of the nature of porotic hyperostosis in three British archaeological populations. MSc thesis, University of Bradford.
139. Williams B, Waddington D, Murray DH, Farquharson C. 2004. Bone strength during growth: influence of growth rate on cortical porosity and mineralization. Calcified Tissue International 74: 236-245.
140. Williams H. 1929. Human paleopathology. Archives of Pathology 7: 839-902.
141. Wood JW, Milner GR, Harpending HC, Weiss KM. 1992. The osteological paradox: problems of inferring prehistoric health from skeletal samples. Current Anthropology 33: 343-370.
142. Zivanovic S. 1985. Ostaci skeleta sa nekropole pored crkve u Deževu. Starinar 36: 151-160.
143. Zivanovic S. 1986. Osnovne antropološke karakteristike skeleta iz nekropole crkve 1 u Trgovištu. Nekropola 2 u trgovištu. Novopazarski zbornik 10: 43-66.
144. Zivanovic S. 1987. Skeleti nekropole crkve 4 na lokalitetu Tabačina u Trgovištu. Novopazarski zbornik 11: 73-91.
145. Zivanovic S. 1988. Antropološka analiza srpskih srednjovekovnih skeleta. Raška baština 3: 235-245.