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Volumn 11, Issue 10, 2006, Pages 757-760

A poor metabolizer for cytochromes P450 2D6 and 2C19: A case report on antidepressant treatment

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; CITALOPRAM; CYTOCHROME P450 2C19; CYTOCHROME P450 2D6; ESCITALOPRAM; MIRTAZAPINE; QUETIAPINE; RISPERIDONE; SERTRALINE; TRAZODONE; TRICYCLIC ANTIDEPRESSANT AGENT; VENLAFAXINE;

EID: 33750017284     PISSN: 10928529     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1092852900014887     Document Type: Article
Times cited : (22)

References (16)
  • 1
    • 0742321734 scopus 로고    scopus 로고
    • Human drug metabolising cytochrome P450 enzymes: Properties and polymorphisms
    • Ingelman-Sundberg M. Human drug metabolising cytochrome P450 enzymes: properties and polymorphisms. Naunyan-Schmiedberg's Arch Pharmacol. 2004;369:89-104.
    • (2004) Naunyan-Schmiedberg's Arch Pharmacol , vol.369 , pp. 89-104
    • Ingelman-Sundberg, M.1
  • 2
    • 0037115525 scopus 로고    scopus 로고
    • Pharmacogenetics affects dosing, efficacy, and toxicity of cytochrome P450-metabolized drugs
    • Rogers JF, Nafziger AN, Bertino JS. Pharmacogenetics affects dosing, efficacy, and toxicity of cytochrome P450-metabolized drugs. Am J Med. 2002;113:746-750.
    • (2002) Am J Med , vol.113 , pp. 746-750
    • Rogers, J.F.1    Nafziger, A.N.2    Bertino, J.S.3
  • 4
    • 2942674322 scopus 로고    scopus 로고
    • Some aspects of genetic polymorphism in the biotransformation of antidepressants
    • Brosen K. Some aspects of genetic polymorphism in the biotransformation of antidepressants. Therapie. 2004;59:5-12.
    • (2004) Therapie , vol.59 , pp. 5-12
    • Brosen, K.1
  • 6
    • 3142519666 scopus 로고    scopus 로고
    • Pharmacogenetics of antidepressants and antipsychotics: The contribution of allelic variations to the phenotype of drug response
    • Kirchheiner J, Nickchen K, Bauer M, et al. Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response. Mol Psychiatry. 2004;9:442-473.
    • (2004) Mol Psychiatry , vol.9 , pp. 442-473
    • Kirchheiner, J.1    Nickchen, K.2    Bauer, M.3
  • 7
    • 29544449443 scopus 로고    scopus 로고
    • Clinical guidelines for using pharmacogenetic testing of CYP450 2D6 and CYP450 2C19 in psychiatry
    • de Leon J, Armstrong SC, Cozza KL. Clinical guidelines for using pharmacogenetic testing of CYP450 2D6 and CYP450 2C19 in psychiatry. Psychosomatics. 2006;47:75-85.
    • (2006) Psychosomatics , vol.47 , pp. 75-85
    • De Leon, J.1    Armstrong, S.C.2    Cozza, K.L.3
  • 8
    • 33645217106 scopus 로고    scopus 로고
    • Incorporating pharmacogenetics into clinical practice: Reality of a new tool in psychiatry
    • Mrazek DA, Smoller JW, de Leon J. Incorporating pharmacogenetics into clinical practice: reality of a new tool in psychiatry. CNS Spectr. 2006;11(suppl 3):1-13.
    • (2006) CNS Spectr , vol.11 , Issue.SUPPL. 3 , pp. 1-13
    • Mrazek, D.A.1    Smoller, J.W.2    De Leon, J.3
  • 9
    • 33745944880 scopus 로고    scopus 로고
    • The AmpliChip CYP450 Test: Personalized medicine has arrived in psychiatry
    • de Leon J. The AmpliChip CYP450 Test: personalized medicine has arrived in psychiatry. Exp Rev Mol Diagn. 2006;6:277-286.
    • (2006) Exp Rev Mol Diagn , vol.6 , pp. 277-286
    • De Leon, J.1
  • 11
    • 12944281041 scopus 로고    scopus 로고
    • Amitriptyline or not, that is the question: Pharmacogenetic testing of CYP2D6 and CYP2C19 identifies patients with low or high risk for side effects in amitriptyline therapy
    • Steimer W, Zopf K, von Amelunxen S, et al. Amitriptyline or not, that is the question: pharmacogenetic testing of CYP2D6 and CYP2C19 identifies patients with low or high risk for side effects in amitriptyline therapy. Clin Chemistry. 2005;51:376-385.
    • (2005) Clin Chemistry , vol.51 , pp. 376-385
    • Steimer, W.1    Zopf, K.2    Von Amelunxen, S.3
  • 12
    • 0036337642 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of racemic venlafaxine and its main metabolites in an everyday clinical setting
    • Reis M, Lundmark J, Bjork H, Bengtsson F. Therapeutic drug monitoring of racemic venlafaxine and its main metabolites in an everyday clinical setting. Ther Drug Monit. 2002;24:545-553.
    • (2002) Ther Drug Monit , vol.24 , pp. 545-553
    • Reis, M.1    Lundmark, J.2    Bjork, H.3    Bengtsson, F.4
  • 13
    • 33645225293 scopus 로고    scopus 로고
    • Heterozygous mutation in CYP2C19 significantly increases the concentration/dose ratio of racemic citalopram and escitalopram (S-citalopram)
    • Rudberg I, Hendset M, Uthus LH, Molden E, Refsum H. Heterozygous mutation in CYP2C19 significantly increases the concentration/dose ratio of racemic citalopram and escitalopram (S-citalopram). Ther Drug Monit. 2006;28:102-105.
    • (2006) Ther Drug Monit , vol.28 , pp. 102-105
    • Rudberg, I.1    Hendset, M.2    Uthus, L.H.3    Molden, E.4    Refsum, H.5
  • 14
    • 0034936466 scopus 로고    scopus 로고
    • Escitalopram (S-citalopram) and its metabolites in vitro: Cytochromes mediating biotransformation, inhibitory effects, and comparison to R-citalopram
    • von Moltke LL, Greenblatt DJ, Giancarlo GM, Granda BW, Harmatz JS, Shader RI. Escitalopram (S-citalopram) and its metabolites in vitro: cytochromes mediating biotransformation, inhibitory effects, and comparison to R-citalopram. Drug Metab Dispos. 2001;29:1102-1109.
    • (2001) Drug Metab Dispos , vol.29 , pp. 1102-1109
    • Von Moltke, L.L.1    Greenblatt, D.J.2    Giancarlo, G.M.3    Granda, B.W.4    Harmatz, J.S.5    Shader, R.I.6
  • 15
    • 8744224452 scopus 로고    scopus 로고
    • Impact of the CYP2D6 ultrarapid metabolizer genotype on mirtazapine pharmacokinetics and adverse events in healthy volunteers
    • Kirchheiner J, Henckel HB, Meineke I, Roots I, Brockmoller J. Impact of the CYP2D6 ultrarapid metabolizer genotype on mirtazapine pharmacokinetics and adverse events in healthy volunteers. J Clin Psychopharmacol. 2004;24:647-652.
    • (2004) J Clin Psychopharmacol , vol.24 , pp. 647-652
    • Kirchheiner, J.1    Henckel, H.B.2    Meineke, I.3    Roots, I.4    Brockmoller, J.5
  • 16
    • 13844320650 scopus 로고    scopus 로고
    • The CYP2D6 poor metabolizer phenotype may be associated with risperidone adverse drug reactions and discontinuation
    • de Leon J, Susce MT, Pan RM, Fairchild M, Koch W, Wedlund PJ. The CYP2D6 poor metabolizer phenotype may be associated with risperidone adverse drug reactions and discontinuation. J Clin Psychiatry. 2005;66:15-27.
    • (2005) J Clin Psychiatry , vol.66 , pp. 15-27
    • De Leon, J.1    Susce, M.T.2    Pan, R.M.3    Fairchild, M.4    Koch, W.5    Wedlund, P.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.