Design and synthesis of N-methylmaleimide indolocarbazole bearing modified 2-acetamino acid moieties as Topoisomerase I inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 2, 2009, Pages 406-409

  Li, Zhiyu ^a   Zhai, Fuming ^a   Zhao, Li ^a   Guo, Qinglong ^a   You, Qidong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Cancer cell cycle; Cytotoxicities; Indolocarbazole derivatives; Topoisomerase I

Indexed keywords

CARBAZOLE DERIVATIVE; DNA TOPOISOMERASE INHIBITOR; MORPHOLINE DERIVATIVE; PIPERAZINE DERIVATIVE;

ARTICLE; CANCER CELL CULTURE; CHEMICAL REACTION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL;

AMINO ACIDS; CARBAZOLES; CELL LINE, TUMOR; DNA TOPOISOMERASES, TYPE I; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; HUMANS;

EID: 57749118596     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.11.061     Document Type: Article

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