Increased activation of the left hippocampus region in Complex PTSD during encoding and recognition of emotional words: A pilot study

Psychiatry Research - Neuroimaging

Volumn 171, Issue 1, 2009, Pages 44-53

  Thomaes, Kathleen ^a,b   Dorrepaal, Ethy ^a   Draijer, Nel P J ^a,b   de Ruiter, Michiel B ^c   Elzinga, Bernet M ^d   van Balkom, Anton J ^a,b   Smoor, Paulien L M ^a,b   Smit, Johannes ^a,b   Veltman, Dick J ^a,b,c  

^a GGZ Foundation for Mental Health Care Buitenamstel   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Childhood abuse; DESNOS; Emotional stimuli; Functional brain imaging; Medial temporal lobe; Memory; Posttraumatic Stress Disorder

Indexed keywords

ADULT; ANATOMICAL VARIATION; ARTICLE; BLOOD OXYGENATION; BRAIN REGION; BRAIN SIZE; CLINICAL ARTICLE; CONTROLLED STUDY; DECLARATIVE MEMORY; EMOTION; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HIPPOCAMPUS; HUMAN; MEMORY DISORDER; MENTAL PATIENT; NEUROANATOMY; PILOT STUDY; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; RECALL; SUBICULUM; TASK PERFORMANCE; TEMPORAL LOBE; WORD RECOGNITION;

ADULT; AFFECT; FEMALE; FUNCTIONAL LATERALITY; HIPPOCAMPUS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; OXYGEN; PILOT PROJECTS; RECOGNITION (PSYCHOLOGY); SPEECH PERCEPTION; STRESS DISORDERS, POST-TRAUMATIC; VOCABULARY;

EID: 57749103732     PISSN: 09254927     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pscychresns.2008.03.003     Document Type: Article

References (55)

1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders IV-Text Revision (DSM-IV-TR) (2000), APA, Washington, DC
2. Ashburner J., and Friston K.J. Voxel-based morphometry-the methods. Neuroimage 11 (2000) 805-821
3. Astur R.S., St Germain S.A., Tolin D., Ford J., Russell D., and Stevens M. Hippocampus function predicts severity of post-traumatic stress disorder. Cyberpsychological Behaviour 9 (2006) 234-240
4. Beck A.T., Steer R.A., and Garbin M.G. Psychometric properties of the Beck Depression Inventory. Clinical Psychology Review 42 (1998) 841-865
5. Bernstein E.M., and Putnam F.W. Development, reliability, and validity of a dissociation scale. Journal of Nervous and Mental Disorders 174 (1986) 727-735
6. Bremner J.D., Narayan M., Staib L.H., Southwick S.M., McGlashan T., and Charney D.S. Neural correlates of memories of childhood sexual abuse in women with and without posttraumatic stress disorder. American Journal of Psychiatry 156 (1999) 1787-1795
7. Bremner J.D., Vythilingam M., Vermetten E., Southwick S.M., McGlashan T., Nazeer A., Khan S., Vaccarino L.V., Soufer R., Garg P.K., Ng C.K., Staib L.H., Duncan J.S., and Charney D.S. MRI and PET study of deficits in hippocampal structure and function in women with childhood sexual abuse and posttraumatic stress disorder. American Journal of Psychiatry 160 (2003) 924-932
8. Bremner J.D., Vythilingam M., Vermetten E., Southwick S.M., McGlashan T., Staib L.H., Soufer R., and Charney D.S. Neural correlates of declarative memory for emotionally valenced words in women with posttraumatic stress disorder related to early childhood sexual abuse. Biological Psychiatry 53 (2003) 879-889
9. Bremner J.D., Vythilingam M., Vermetten E., Vaccarino V., and Charney D.S. Deficits in hippocampal and anterior cingulate functioning during verbal declarative memory encoding in midlife major depression. American Journal of Psychiatry 161 (2004) 637-645
10. Breslau N., Kessler R.C., Chilcoat H.D., Schultz L.R., Davis G.C., and Andreski P. Trauma and posttraumatic stress disorder in the community: the 1996 Detroit Area Survey of Trauma. Archives of General Psychiatry 55 (1998) 626-632
11. Chemtob C.M., Roitblat H.L., Hamada R.S., Muraoka M.Y., Carlson J.G., and Bauer G.B. Compelled attention: the effects of viewing trauma-related stimuli on concurrent task performance in posttraumatic stress disorder. Journal of Traumatic Stress 12 (1999) 309-326
12. Davidson J.R., Book S.W., Colket J.T., Tupler L.A., Roth S., David D., Hertzberg M., Mellman T., Beckham J.C., Smith R.D., Davison R.M., Katz R., and Feldman M.E. Assessment of a new self-rating scale for post-traumatic stress disorder. Psychological Medicine 27 (1997) 153-160
13. de Ruiter, M.B., Veltman, D.J., Phaf, R.H., van Dyck, R., 2007. Negative words enhance recognition in nonclinical high dissociators: an fMRI study. Neuroimage 37, 323-334.
14. Derogatis L.R., Lipman R.S., and Covi L. SCL-90: an outpatient psychiatric rating scale-preliminary report. Psychopharmacology Bulletin 9 (1973) 13-28
15. Draijer N. Structured Trauma Interview (1989), Free University, Department of Psychiatry, Amsterdam
16. Draijer N. Sexual Traumatization in Childhood. Long-term Impact of Sexual Abuse of Girls (1990), SUA, Amsterdam
17. Driessen M., Herrmann J., Stahl K., Zwaan M., Meier S., Hill A., Osterheider M., and Petersen D. Magnetic resonance imaging volumes of the hippocampus and the amygdala in women with borderline personality disorder and early traumatization. Archives of General Psychiatry 57 (2000) 1115-1122
18. Driessen M., Beblo T., Mertens M., Piefke M., Rullkoetter N., Silva-Saavedra A., Reddemann L., Rau H., Markowitsch H.J., Wulff H., Lange W., and Woermann F.G. Posttraumatic stress disorder and fMRI activation patterns of traumatic memory in patients with borderline personality disorder. Biological Psychiatry 55 (2004) 603-611
19. Elzinga B.M., and Bremner J.D. Are the neural substrates of memory the final common pathway in posttraumatic stress disorder (PTSD)?. Journal of Affective Disorders 70 (2002) 1-17
20. Ehling T., Nijenhuis E.R., and Krikke A.P. Volume of discrete brain structures in complex dissociative disorders: preliminary findings. Progress in Brain Research 167 (2007) 307-310
21. First M.B., Spitzer R.L., Williams J.B.W., and Gibbon M. Structured Clinical Interview for DSM-IV diagnoses (SCID-I) (1995), APA, Washington, DC
22. Francati V., Vermetten E., and Bremner J.D. Functional neuroimaging studies in posttraumatic stress disorder: review of current methods and findings. Depression and Anxiety 24 (2007) 202-218
23. Ford J.D., Stockton P., Kaltman S., and Green B.L. Disorders of extreme stress (DESNOS) symptoms are associated with type and severity of interpersonal trauma exposure in a sample of healthy young women. Journal of Interpersonal Violence 21 (2006) 1399-1416
24. Freeman T., Kimbrell T., Booe L., Myers M., Cardwell D., Lindquist D.M., Hart J., and Komoroski R.A. Evidence of resilience: neuroimaging in former prisoners of war. Psychiatry Research Neuroimaging 146 (2006) 59-64
25. Golier J.A., Yehuda R., De Santi S., Segal S., Dolan S., and de Leon M.J. Absence of hippocampal volume differences in survivors of the Nazi Holocaust with and without posttraumatic stress disorder. Psychiatric Research Neuroimaging 139 (2005) 53-64
26. Green B.L., Goodman L.A., Krupnick J.L., Corcoran C.B., Petty R.M., Stockton P., and Stern N.M. Outcomes of single versus multiple trauma exposure in a screening sample. Journal of Traumatic Stress 13 (2000) 271-286
27. Heim C., Newport D.J., Wagner D., Wilcox M.M., Miller A.H., and Nemeroff C.B. The role of early adverse experience and adulthood stress in the prediction of neuroendocrine stress reactivity in women: a multiple regression analysis. Depression and Anxiety 15 (2002) 117-125
28. Herman J.L. Complex PTSD: a syndrome in survivors of prolonged and repeated trauma. Journal of Traumatic Stress 5 (1992) 377-391
29. Höing M. Hulp aan slachtoffers van seksueel geweld (2003), Eburon, Delft
30. Jatzko A., Rothenhofer S., Schmitt A., Gaser C., Demirakca T., Weber-Fahr W., Wessa M., Magnotta V., and Braus D.F. Hippocampal volume in chronic posttraumatic stress disorder (PTSD): MRI study using two different evaluation methods. Journal of Affective Disorders 94 (2006) 121-126
31. Jenkins M.A., Langlais P.J., Delis D., and Cohen R. Learning and memory in rape victims with posttraumatic stress disorder. American Journal of Psychiatry 155 (1998) 278-279
32. Karl A., Schaefer M., Malta L.S., Dorfel D., Rohleder N., and Werner A. A meta-analysis of structural brain abnormalities in PTSD. Neuroscience and Biobehavioral Reviews 30 (2006) 1004-1031
33. Kensinger E.A., and Schacter D.L. Retrieving accurate and distorted memories: neuroimaging evidence for effects of emotion. Neuroimage 27 (2005) 167-177
34. Lanius R.A., Williamson P.C., Hopper J., Densmore M., Boksman K., Gupta M.A., Neufeld R.W., Gati J.S., and Menon R.S. Recall of emotional states in posttraumatic stress disorder: an fMRI investigation. Biological Psychiatry 53 (2003) 204-210
35. McNally R.J. Cognitive abnormalities in post-traumatic stress disorder. Trends in Cognitive Science 10 (2006) 271-277
36. Pfohl N., and Zimmerman M. Structured Interview for DSM-IV Personality (SIDP-IV) (1997), American Psychiatric Press, Washington, DC.
37. Rauch S.L., Shin L.M., and Phelps E.A. Neurocircuitry models of posttraumatic stress disorder and extinction: human neuroimaging research-past, present, and future. Biological Psychiatry 60 (2006) 376-382
38. Rolls E.T., and Kesner R.P. A computational theory of hippocampal function, and empirical tests of the theory. Progress in Neurobiology 79 (2006) 1-48
39. Sapolsky R.M. Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders. Archives of General Psychiatry 57 (2000) 925-935
40. Shin L.M., Whalen P.J., Pitman R.K., Bush G., Macklin M.L., Lasko N.B., Orr S.P., McInerney S.C., and Rauch S.L. An fMRI study of anterior cingulate function in posttraumatic stress disorder. Biological Psychiatry 50 (2001) 932-942
41. Shin L.M., Shin P.S., Heckers S., Krangel T.S., Macklin M.L., Orr S.P., Lasko N., Segal E., Makris N., Richert K., Levering J., Schacter D.L., Alpert N.M., Fischman A.J., Pitman R.K., and Rauch S.L. Hippocampal function in posttraumatic stress disorder. Hippocampus 14 (2004) 292-300
42. Stein M.B., Koverola C., Hanna C., Torchia M.G., and McClarty B. Hippocampal volume in women victimized by childhood sexual abuse. Psychological Medicine 27 (1997) 951-959
43. Steinberg M., Rounsaville B., and Cicchetti D.V. The Structured Clinical Interview for DSM-III-R Dissociative Disorders: preliminary report on a new diagnostic instrument. American Journal of Psychiatry 147 (1990) 76-82
44. Sutker P.B., Allain Jr. A.N., Johnson J.L., and Butters N.M. Memory and learning performances in POW survivors with history of malnutrition and combat veteran controls. Archives of Clinical Neuropsychology 7 (1992) 431-444
45. Terr L.C. Childhood traumas: an outline and overview. American Journal of Psychiatry 148 (1991) 10-20
46. Van der Kolk, B.A., Pelcovitz, D., Herman, J.L., Roth, S., Kaplan, S., Spitzer, R.L., 1992. The Disorders of Extreme Stress Inventory Unpublished measure.
47. Van Der Kolk B.A., Pelcovitz D., Roth S., Mandel F.S., McFarlane A., and Herman J.L. Dissociation, somatization, and affect dysregulation: the complexity of adaptation of trauma. American Journal of Psychiatry 153 (1996) 83-93
48. Vasterling J.J., Brailey K., Constans J.I., and Sutker P.B. Attention and memory dysfunction in posttraumatic stress disorder. Neuropsychology 12 (1998) 125-133
49. Vermetten E., Schmahl C., Lindner S., Loewenstein R.J., and Bremner J.D. Hippocampal and amygdalar volumes in dissociative identity disorder. American Journal of Psychiatry 163 (2006) 630-636
50. Videbech P., and Ravnkilde B. Hippocampal volume and depression: a meta-analysis of MRI studies. American Journal of Psychiatry 161 (2004) 1957-1966
51. Videbech P., Ravnkilde B., Pedersen T.H., Hartvig H., Egander A., Clemmensen K., Rasmussen N.A., Andersen F., Gjedde A., and Rosenberg R. The Danish PET/depression project: clinical symptoms and cerebral blood flow. A regions-of-interest analysis. Acta Psychiatrica Scandinavia 106 (2002) 35-44
52. Vythilingam M., Heim C., Newport J., Miller A.H., Anderson E., Bronen R., Brummer M., Staib L., Vermetten E., Charney D.S., Nemeroff C.B., and Bremner J.D. Childhood trauma associated with smaller hippocampal volume in women with major depression. American Journal of Psychiatry 159 (2002) 2072-2080
53. Wittmann B.C., Schott B.H., Guderian S., Frey J.U., Heinze H.J., and Duzel E. Reward-related FMRI activation of dopaminergic midbrain is associated with enhanced hippocampus-dependent long-term memory formation. Neuron 45 (2005) 459-467
54. Yehuda R., Golier J.A., Tischler L., Harvey P.D., Newmark R., Yang R.K., and Buchsbaum M.S. Hippocampal volume in aging combat veterans with and without post-traumatic stress disorder: relation to risk and resilience factors. Journal of Psychiatric Research 41 (2007) 435-445
55. Zlotnick C., Zakriski A.L., Shea M.T., Costello E., Begin A., Pearlstein T., and Simpson E. The long-term sequelae of sexual abuse: support for a complex posttraumatic stress disorder. Journal of Traumatic Stress 9 (1996) 195-205