Synthesis of biflavones having a 6-O-7'' linkage and effects on cyclooxygenase-2 and inducible nitric oxide synthase

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 1, 2009, Pages 74-76

  Che, Haiyan ^a   Park, Byung Kyu ^a   Lim, Hyun ^a   Kim, Hyun Pyo ^a   Chang, Hyeun Wook ^b   Jeong, Jin Hyun ^c   Park, Haeil ^a  

^a Kangwon National University   (South Korea)

^b Yeungnam University   (South Korea)

^c Kyung Hee University   (South Korea)

Author keywords

6 O 7 biflavonoid; Anti inflammation; Cyclooxygenase; Nitric oxide synthase

Indexed keywords

BIFLAVONE DERIVATIVE; CYCLOOXYGENASE 2; FLAVONE DERIVATIVE; INDUCIBLE NITRIC OXIDE SYNTHASE; PROSTAGLANDIN E2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; DRUG EFFECT; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; FEMALE; IC 50; NONHUMAN; REACTION ANALYSIS; STRUCTURE ANALYSIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BIFLAVONOIDS; CELL LINE; CYCLOOXYGENASE 2 INHIBITORS; DINOPROSTONE; FLAVONES; INHIBITORY CONCENTRATION 50; MACROPHAGES; MICE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 57749085385     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.11.017     Document Type: Article

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