The Use of Shift Reagents in Ion Mobility-Mass Spectrometry: Studies on the Complexation of an Active Pharmaceutical Ingredient with Polyethylene Glycol Excipients

Journal of the American Society for Mass Spectrometry

Volumn 20, Issue 1, 2009, Pages 1-9

  Howdle, Mark D ^a   Eckers, Christine ^b   Laures, Alice M F ^b   Creaser, Colin S ^a  

^a LOUGHBOROUGH UNIVERSITY   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTROSPRAY IONIZATION; ETHYLENE GLYCOL; GLYCOLS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION OF GASES; IONS; MASS SPECTROMETERS; MASS SPECTROMETRY; OLIGOMERS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; POLYMERS; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS; THERMOPLASTICS; TUBES (COMPONENTS);

ACTIVE PHARMACEUTICAL INGREDIENTS; CATIONIZED; DRIFT TIMES; DRIFT TUBES; INDUCED DISSOCIATIONS; ION MOBILITIES; ION MOBILITY SPECTROMETRIES; LAMIVUDINE; MOLECULAR WEIGHT IONS; NONCOVALENT COMPLEXES; PRECURSOR COMPLEXES; PROTONATED; QUADRUPOLE; SHIFT REAGENTS; TIME OF FLIGHTS;

DRUG PRODUCTS;

LAMIVUDINE; MACROGOL;

ARTICLE; COLLISIONALLY ACTIVATED DISSOCIATION; COMPLEX FORMATION; DRUG FORMULATION; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; ION MOBILITY SPECTROMETRY; MASS SPECTROMETRY; MOLECULAR WEIGHT; PROTON TRANSPORT;

ALGORITHMS; ANTI-HIV AGENTS; CATIONS; CHEMISTRY, PHARMACEUTICAL; DRUG COMBINATIONS; EXCIPIENTS; LAMIVUDINE; POLYETHYLENE GLYCOLS; PROTONS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; ZIDOVUDINE;

EID: 57649219979     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jasms.2008.10.002     Document Type: Article

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