Metabolite Imaging Using Matrix-Enhanced Surface-Assisted Laser Desorption/Ionization Mass Spectrometry (ME-SALDI-MS)

Journal of the American Society for Mass Spectrometry

Volumn 20, Issue 1, 2009, Pages 80-88

  Liu, Qiang ^a   Xiao, Yongsheng ^a   Pagan Miranda, Coral ^a   Chiu, Yu Matthew ^a   He, Lin ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DESORPTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION; LASERS; MASS SPECTROMETERS; MASS SPECTROMETRY; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS;

ANALYTE; BIOIMAGING; BRAIN TISSUES; DETECTION SENSITIVITIES; DIMYRISTOYL; ENHANCED SURFACES; IONIZATION MECHANISMS; LASER DESORPTION/IONIZATION; LASER DESORPTION/IONIZATION MASS SPECTROMETRIES; MOLECULAR IONS; MOUSE HEARTS; PHOSPHOCHOLINE;

COMPOSITE MICROMECHANICS;

DIMYRISTOYLPHOSPHATIDYLCHOLINE;

ARTICLE; BRAIN TISSUE; DESORPTION; IMAGING SYSTEM; LASER; MASS SPECTROMETRY; MATRIX ENHANCED SURFACE ASSISTED LASER DESORPTION IONIZATION MASS SPECTROMETRY; QUALITATIVE ANALYSIS; SENSITIVITY ANALYSIS;

ANIMALS; BRAIN CHEMISTRY; CEREBELLUM; CEREBRUM; DIAGNOSTIC IMAGING; DIMYRISTOYLPHOSPHATIDYLCHOLINE; FEMALE; MICE; MYOCARDIUM; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 57649159179     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jasms.2008.09.011     Document Type: Article

References (34)

1. Caprioli R.M., Farmer T.B., and Gile J. Molecular Imaging of Biological Samples: Localization of Peptides and Proteins Using MALDI-TOF MS. Anal. Chem 69 (1997) 4751-4760
2. Ostrowski S.G., Van Bell C.T., Winograd N., and Ewing A.G. Mass Spectrometric Imaging of Highly Curved Membranes During Tetrahymena Mating. Science 305 (2004) 71-73
3. Altelaar A.F.M., Van Minnen J., Jimenez C.R., Heeren R.M.A., and Piersma S.R. Direct Molecular Imaging of Lymnaea stagnalis Nervous Tissue at Subcellular Spatial Resolution by Mass Spectrometry. Anal. Chem 77 (2005) 735-741
4. Drexler D.M., Garrett T.J., Cantone J.L., Diters R.W., Mitroka J.G., Prieto Conaway M.C., Adams S.P., Yost R.A., and Sanders M. Utility of Imaging Mass Spectrometry (IMS) by Matrix-Assisted Laser Desorption Ionization (MALDI) on an Ion Trap Mass Spectrometer in the Analysis of Drugs and Metabolites in Biological Tissues. J. Pharmacol. Toxicol. Methods 55 (2007) 279-288
5. Nemes P., and Vertes A. Laser Ablation Electrospray Ionization for Atmospheric Pressure, in Vivo, and Imaging Mass Spectrometry. Anal. Chem 79 (2007) 8098-8106
6. Liu Q., Guo Z., and He L. Mass Spectrometry Imaging of Small Molecules Using Desorption/Ionization on Silicon. Anal. Chem 79 (2007) 3535-3541
7. n of Small Molecules. 1. Imaging of Cerebrosides Directly from Rat Brain Tissue. Anal. Chem 79 (2007) 2373-2385
8. Cornett D.S., Reyzer M.L., Chaurand P., and Caprioli R.M. MALDI Imaging Mass Spectrometry: Molecular Snapshots of Biochemical Systems. Nat. Methods 4 (2007) 828-833
9. Wu K.J., and Odom R.W. Matrix-Enhanced Secondary Ion Mass Spectrometry: A Method for Molecular Analysis of Solid Surfaces. Anal. Chem 68 (1996) 873-882
10. Cooks R.G., Ouyang Z., Takats Z., and Wiseman J.M. Ambient Mass Spectrometry. Science 311 (2006) 1566-1570
11. Shiea J., Huang M.-Z., Hsu H.-J., Lee C.-Y., Yuan C.-H., Beech I., and Sunner J. Electrospray-Assisted Laser Desorption/Ionization Mass Spectrometry for Direct Ambient Analysis of Solids. Rapid Commun. Mass Spectrom 19 (2005) 3701-3704
12. Coon J.J., Steele H.A., Laipis P.J., and Harrison W.W. Laser Desorption-Atmospheric Pressure Chemical Ionization: A Novel Ion Source for the Direct Coupling of Polyacrylamide Gel Electrophoresis to Mass Spectrometry. J. Mass. Spectrom 37 (2002) 1163-1167
13. Sampson J.S., Hawkridge A.M., and Muddiman D.C. Generation and Detection of Multiply-Charged Peptides and Proteins by Matrix-Assisted Laser Desorption Electrospray Ionization (MALDESI) Fourier Transform Ion Cyclotron Resonance Mass Spectrometry. J. Am. Soc. Mass Spectrom 17 (2006) 1712-1716
14. Tanaka K., Waki H., Ido Y., Akita S., Yoshida Y., and Yohida T. Protein and Polymer Analyses Up to m/z 100,000 by Laser Ionization Time-of-Flight Mass Spectrometry. Rapid Commun. Mass Spectrom 2 (1988) 151-153
15. Sunner J., Dratz E., and Chen Y.-C. Graphite Surface-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry of Peptides and Proteins from Liquid Solutions. Anal. Chem 67 (1995) 4335-4342
16. Dale M.J., Knochenmuss R., and Zenobi R. Graphite/Liquid Mixed Matrixes for Laser Desorption/Ionization Mass Spectrometry. Anal. Chem 68 (1996) 3321-3329
17. Dale M., Knochenmuss R., and Zenobi R. Two-Phase Matrix-Assisted Laser Desorption/Ionization: Matrix Selection and Sample Pretreatment for Complex Anionic Analytes. Rapid Commun. Mass Spectrom 11 (1997) 136-142
18. Zhou H., Xu S., Ye M., Feng S., Pan C., Jiang X., Li X., Han G., Fu Y., and Zou H. Zirconium Phosphonate-Modified Porous Silicon for Highly Specific Capture of Phosphopeptides and MALDI-TOF MS Analysis. J. Proteome Res 5 (2006) 2431-2437
19. Liu Q., and He L. Quantitative Study of Solvent and Surface Effects on Analyte Ionization in Desorption Ionization on Silicon (DIOS) Mass Spectrometry. J. Am. Soc. Mass Spectrom 19 (2008) 8-13
20. Chen C., Chen H., Aleksandrov A., and Orlando T.M. Roles of Water, Acidity, and Surface Morphology in Surface-Assisted Laser Desorption/Ionization of Amino Acids. J. Phys. Chem. C 112 (2008) 6953-6960
21. Finkel N.H., Prevo B.G., Velev O.D., and He L. Ordered Silicon Nanocavity Arrays in Surface-Assisted Desorption/Ionization Mass Spectrometry. Anal. Chem 77 (2005) 1088-1095
22. Chaurand P., Schriver K.E., and Caprioli R.M. Instrument Design and Characterization for High Resolution MALDI-MS Imaging of Tissue Sections. J. Mass Spectrom 42 (2007) 476-489
23. Agar N.Y.R., Yang H.W., Carroll R.S., Black P.M., and Agar J.N. Matrix Solution Fixation: Histology-Compatible Tissue Preparation for MALDI Mass Spectrometry Imaging. Anal. Chem 79 (2007) 7416-7423
24. Hankin J.A., Barkley R.M., and Murphy R.C. Sublimation as a Method of Matrix Application for Mass Spectrometric Imaging. J. Am. Soc. Mass Spectrom 18 (2007) 1646-1652
25. McCombie G., and Knochenmuss R. Small-Molecule MALDI Using the Matrix Suppression Effect to Reduce or Eliminate Matrix Background Interferences. Anal. Chem 76 (2004) 4990-4997
26. Dreisewerd K. The Desorption Process in MALDI. Chem. Rev 103 (2003) 395-426
27. Knochenmuss R. Ion Formation Mechanisms in UV-MALDI. Analyst 131 (2006) 966-986
28. Alimpiev S., Grechnikov A., Sunner J., Karavanskii V., Simanovsky Y., Zhabin S., and Nikiforov S. On the Role of Defects and Surface Chemistry for Surface-Assisted Laser Desorption Ionization from Silicon. J. Chem. Phys 128 (2008) 014711
29. Luo G., Chen Y., Daniels H., Dubrow R., and Vertes A. Internal Energy Transfer in Laser Desorption/Ionization from Silicon Nanowires. J. Phys. Chem. B 110 (2006) 13381-13386
30. Dreisewerd K., Schurenberg M., Karas M., and Hillenkamp F. Influence of the Laser Intensity and Spot Size on the Desorption of Molecules and Ions in Matrix-Assisted Laser Desorption/Ionization with a Uniform Beam Profile. Int. J. Mass Spectrom. Ion Processes 141 (1995) 127-148
31. Schuerenberg M., Dreisewerd K., and Hillenkamp F. Laser Desorption/Ionization Mass Spectrometry of Peptides and Proteins with Particle Suspension Matrixes. Anal. Chem 71 (1999) 221-229
32. Alimpiev S., Nikiforov S., Karavanskii V., Minton T., and Sunner J. On the Mechanism of Laser-Induced Desorption-Ionization of Organic Compounds from Etched Silicon and Carbon Surfaces. J. Chem. Phys 115 (2001) 1891-1901
33. Puolitaival S.M., Burnum K.E., Cornett D.S., and Caprioli R.M. Solvent-Free Matrix Dry-Coating for MALDI Imaging of Phospholipids. J. Am. Soc. Mass Spectrom 19 (2008) 882-886
34. Sjovall P., Johansson B., and Lausmaa J. Localization of Lipids in Freeze-Dried Mouse Brain Sections by Imaging TOF-SIMS. Appl. Surf. Sci 252 (2006) 6966-6974