Laser desorption/ionization mass spectrometry of peptides and proteins with particle suspension matrixes

Analytical Chemistry

Volumn 71, Issue 1, 1999, Pages 221-229

  Schürenberg, Martin ^a,b   Dreisewerd, Klaus ^a,b   Hillenkamp, Franz ^a,b  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b BRUKER DALTONIK GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; IONIZATION; LASER; MASS SPECTROMETRY; PARTICLE SIZE; PROTEIN ANALYSIS;

EID: 0032952484     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac980634c     Document Type: Article

References (3)

1. By "chemical matrix" is meant a preferentially organic compound that is either a liquid or that dissolves homogeneously in a suitable solvent and that simultaneously acts as the light absorber and interacts with the analyte in the ion-formation process. For "suspension matrixes" the two functions appear to be split between the particles (absorption) and ionization (liquid, possibly a liquid surface interaction). Karas, M.; Bachmann, D.; Hillenkamp, F. Anal. Chem. 1985, 57, 2935.
2. Karas, M.; Bachmann, D.; Bahr, U.; Hillenkamp, F. Int. J. Mass Spectrom. Ion Processes 1987, 78, 53.
3. Karas, M.; Hillenkamp, F. Anal. Chem. 1988, 60, 2299.