Tandem Mass Spectrometry of Poly(Methacrylic Acid) Oligomers Produced by Negative Mode Electrospray Ionization

Journal of the American Society for Mass Spectrometry

Volumn 20, Issue 1, 2009, Pages 25-33

  Giordanengo, Rémi ^a   Viel, Stéphane ^a   Allard Breton, Béatrice ^b   Thévand, André ^a   Charles, Laurence ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

^b ARKEMA   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDS; CARBON DIOXIDE; CARBOXYLATION; CARBOXYLIC ACIDS; DEHYDRATION; DEWATERING; DISSOCIATION; ELECTROSPRAY IONIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION OF LIQUIDS; IONS; MASS SPECTROMETERS; MASS SPECTROMETRY; OLIGOMERS; ORGANIC ACIDS; POLYMERS; RESINS; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS;

ACCURATE MASS MEASUREMENTS; ACID GROUPS; ACRYLIC ACIDS; CARBON DIOXIDE MOLECULES; COLLISIONAL ACTIVATIONS; DECARBOXYLATION REACTIONS; DISSOCIATION MECHANISMS; ELECTROSPRAY; FRAGMENT IONS; METHACRYLIC ACIDS; PENDANT GROUPS; POLIES (ACRYLIC ACID); POLYMERIZATION DEGREES; PRECURSOR IONS; TANDEM MASS SPECTROMETRIES; THERMAL DEGRADATIONS; WATER MOLECULES;

MOLECULES;

ACID ANHYDRIDE; CARBON DIOXIDE; POLYACRYLIC ACID; POLYMETHACRYLIC ACID;

ARTICLE; CHEMICAL STRUCTURE; DECARBOXYLATION; DEGRADATION; ELECTROSPRAY MASS SPECTROMETRY; ELIMINATION REACTION; POLYMERIZATION; PROTON TRANSPORT; TANDEM MASS SPECTROMETRY;

EID: 57649157662     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jasms.2008.09.019     Document Type: Article

References (45)

1. Forster S., Abetz V., and Muller A.H.E. Polyelectrolyte Block Copolymer Micelles. In: Schmidt M. (Ed). Polyelectrolytes with Defined Molecular Architecture II Vol. CLXVI (2004), Lavoisier, Paris, France 173-210
2. Mun G.A., Nurkeeva Z.S., Irmukhametova G.S., and Guven O. Synthesis, Characterization, and Adsorption Study of the Uranyl Ions by Hydrogels Based on Polyethylene Glycol and Methacrylic Acid Copolymers. Nucl. Instrum. Methods Phys. Res. Sect. B 265 (2007) 379-384
3. Colombani O., Ruppel M., Schubert F., Zettl H., Pergushov D.V., and Muller A.H.E. Synthesis of Poly(n-Butyl Acrylate)-Block-Poly(Acrylic Acid) Diblock Copolymers by ATRP and Their Micellization in Water. Macromolecules 40 (2007) 4338-4350
4. Colombani O., Ruppel M., Burkhardt M., Drechsler M., Schumacher M., Gradzielski M., Schweins R., and Muller A.H.E. Structure of Micelles of Poly(n-Butyl Acrylate)-Block-Poly (Acrylic Acid) Diblock Copolymers in Aqueous Solution. Macromolecules 40 (2007) 4351-4362
5. Burkhardt M., Martinez-Castro N., Tea S., Drechsler M., Babin I., Grishagin I., Schweins R., Pergushov D.V., Gradzielski M., Zezin A.B., and Muller A.H.E. Polyisobutylene-Block-Poly(Methacrylic Acid) Diblock Copolymers: Self-Assembly in Aqueous Media. Langmuir 23 (2007) 12864-12874
6. Pergushov D.V., Remizova E.V., Feldthusen J., Zezin A.B., Muller A.H.E., and Kabanov V.A. Novel Water-Soluble Micellar Interpolyelectrolyte Complexes. J. Phys. Chem. B 107 (2003) 8093-8096
7. Montaudo M.S. Mass Spectra of Copolymers. Mass Spectrom. Rev 21 (2002) 108-144
8. Koster S., Duursma M.C., Boon J.J., Nielen M.W.F., de Koster C.G., and Heeren R.M.A. Structural Analysis of Synthetic Homo- and Copolyesters by Electrospray Ionization on a Fourier Transform Ion Cyclotron Resonance Mass Spectrometer. J. Mass Spectrom 35 (2000) 739-748
9. Jackson A.T., Scrivens J.H., Williams J.P., Baker E.S., Gidden J., and Bowers M.T. Microstructural and Conformational Studies of Polyether Copolymers. Int. J. Mass Spectrom 238 (2004) 287-297
10. Girod M., Phan T.N., and Charles L. Microstructural Study of A Nitroxide-Mediated Poly(Ethylene Oxide)/Polystyrene Block Copolymer (PEO-b-PS) by Electrospray Tandem Mass Spectrometry. J. Am. Soc. Mass Spectrom 19 (2008) 1163-1175
11. Lattimer R.P. Tandem Mass-Spectrometry of Lithium-Attachment Ions from Polyglycols. J. Am. Soc. Mass Spectrom 3 (1992) 225-234
12. Lattimer R.P. Tandem Mass-Spectrometry of Poly(Ethylene Glycol) Lithium-Attachment Ions. J. Am. Soc. Mass Spectrom 5 (1994) 1072-1080
13. Botrill A.R., Giannakopulos A.E., Millichope A., Lee K.S., and Derrick P.J. Combination of Time-of-Flight Mass Analyzers with Magnetic-Sector Instruments: In-Line and Perpendicular Arrangements. Applications to Poly(Ethylene Glycol) with Long-Chain End Groups. Eur. J. Mass Spectrom 6 (2000) 225-232
14. Bottrill A.R., Giannakopulos A.E., Waterson C., Haddleton D.M., Lee K.S., and Derrick P.J. Determination of End Groups of Synthetic Polymers by Matrix-Assisted Laser Desorption/Ionization: High-Energy Collision-Induced Dissociation. Anal. Chem 71 (1999) 3637-3641
15. Chen R., and Li L. Lithium and Transition Metal Ions Enable Low Energy Collision-Induced Dissociation of Polyglycols in Electrospray Ionization Mass Spectrometry. J. Am. Soc. Mass Spectrom 12 (2001) 832-839
16. Chen R., Yu X.L., and Li L. Characterization of Poly(Ethylene glycol) Esters Using Low Energy Collision-Induced Dissociation in Electrospray Ionization Mass Spectrometry. J. Am. Soc. Mass Spectrom 13 (2002) 888-897
17. Girod M., Carissan Y., Humbel S., and Charles L. Tandem Mass Spectrometry of Doubly Charged Poly(Ethylene Oxide) Oligomers Produced by Electrospray Ionization. Int. J. Mass Spectrom 272 (2008) 1-11
18. Hoteling A.J., Kawaoka K., Goodberlet M.C., Yu W.M., and Owens K.G. Optimization of Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Collision-Induced Dissociation Using Poly(Ethylene Glycol). Rapid Commun. Mass Spectrom 17 (2003) 1671-1676
19. Jackson A.T., Green M.R., and Bateman R.H. Generation of End-Group Information from Polyethers by Matrix-Assisted Laser Desorption/Ionization Collision-Induced Dissociation Mass Spectrometry. Rapid Commun. Mass Spectrom 20 (2006) 3542-3550
20. Jackson A.T., Williams J.P., and Scrivens J.H. Desorption Electrospray Ionization Mass Spectrometry and Tandem Mass Spectrometry of Low Molecular Weight Synthetic Polymers. Rapid Commun. Mass Spectrom 20 (2006) 2717-2727
21. Jackson A.T., Yates H.T., Scrivens J.H., Critchley G., Brown J., Green M.R., and Bateman R.H. The Application of Matrix-Assisted Laser Desorption/Ionization Combined with Collision-Induced Dissociation to the Analysis of Synthetic Polymers. Rapid Commun. Mass Spectrom 10 (1996) 1668-1674
22. Okuno S., Kiuchi M., and Arakawa R. Structural Characterization of Polyethers Using Matrix-Assisted Laser Desorption/Ionization Quadrupole Ion Trap Time-of-Flight Mass Spectrometry. Eur. J. Mass Spectrom 12 (2006) 181-187
23. Hoteling A.J., and Owens K.G. Improved PSD and CID on a MALDI-TOF MS. J. Am. Soc. Mass Spectrom 15 (2004) 523-535
24. Pastor S.J., and Wilkins C.L. Sustained Off-Resonance Irradiation and Collision-Induced Dissociation for Structural Analysis of Polymers by MALDI-FT-MS. Int. J. Mass Spectrom 175 (1998) 81-92
25. Gies A.P., Vergne M.J., Orndorff R.L., and Hercules D.M. MALDI-TOF/TOF CID Study of Polystyrene Fragmentation Reactions. Macromolecules 40 (2007) 7493-7504
26. Jackson A.T., Bunn A., Hutchings L.R., Kiff F.T., Richards R.W., Williams J., Green M.R., and Bateman R.H. The Generation of End Group Information from Poly(Styrene)s by Means of Matrix-Assisted Laser Desorption/Ionization-Collision Induced Dissociation. Polymer 41 (2000) 7437-7450
27. Jackson A.T., Yates H.T., Scrivens J.H., Green M.R., and Bateman R.H. Matrix-Assisted Laser Desorption/Ionization-Collision Induced Dissociation of Poly(Atyrene). J. Am. Soc. Mass Spectrom 9 (1998) 269-274
28. Polce M.J., Ocampo M., Quirk R.P., and Wesdemiotis C. Tandem Mass Spectrometry Characteristics of Silver-Cationized Polystyrenes: Backbone Degradation Via Free Radical Chemistry. Anal. Chem 80 (2008) 347-354
29. Polce M.J., Ocampo M., Quirk R.P., Leigh A.M., and Wesdemiotis C. Tandem Mass Spectrometry Characteristics of Silver-Cationized Polystyrenes: Internal Energy, Size, and Chain End Versus Backbone Substituent Effects. Anal. Chem 80 (2008) 355-362
30. Scrivens J.H., Jackson A.T., Yates H.T., Green M.R., Critchley G., Brown J., Bateman R.H., Bowers M.T., and Gidden J. The Effect of the Variation of Cation in the Matrix-Assisted Laser Desorption/Ionization Collision Induced Dissociation (MALDI-CID) Spectra of Oligomeric Systems. Int. J. Mass Spectrom 165/166 (1997) 363-375
31. Jackson A.T., Slade S.E., and Scrivens J.H. Characterization of Poly(Alkyl Methacrylate)s by Means of Electrospray Ionization-Tandem Mass Spectrometry (ESI-MS/MS). Int. J. Mass Spectrom 238 (2004) 265-277
32. Jackson A.T., Yates H.T., Scrivens J.H., Green M.R., and Bateman R.H. Utilizing Matrix-Assisted Laser Desorption/Ionization-Collision Induced Dissociation for the Generation of Structural Information from Poly(Alkyl methacrylates). J. Am. Soc. Mass Spectrom 8 (1997) 1206-1213
33. Lattimer R.P. Pyrolysis Mass Spectrometry of Acrylic Acid Polymers. J. Anal. Appl. Pyrolysis 68/69 (2003) 3-14
34. Maurer J.J., Eustace D.J., and Ratcliffe C.T. Thermal Characterization of Poly(Acrylic Acid). Macromolecules 20 (1987) 196-202
35. Wyatt M.F., Schaeffer N., Tan B., and Cooper A.I. Strategies for the Analysis of Poly(Methacrylic Acid) by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry. J. Am. Soc. Mass Spectrom 18 (2007) 1507-1510
36. Saito R., and Yamaguchi K. Synthesis of Cyclic Methacrylic Acid Oligomers by Atom Transfer Radical Polymerization. J. Polym. Sci. Part A Polym. Chem 43 (2005) 6262-6271
37. Saito R., and Kobayashi H. Synthesis of Polymers by Template Polymerization. 2. Effects of Solvent and Polymerization Temperature. Macromolecules 35 (2002) 7207-7213
38. Burkoth A.K., and Anseth K.S. MALDI-TOF Characterization of Highly Cross-Linked, Degradable Polymer Networks. Macromolecules 32 (1999) 1438-1444
39. Charles L. Influence of Internal Standard Charge State on the Accuracy of Mass Measurements in Orthogonal Acceleration Time-of-Flight Mass Spectrometers. Rapid Commun. Mass Spectrom 22 (2008) 151-155
40. Willker W., Leibfritz D., Kerssebaum R., and Bermel W. Gradient Selection in Inverse Heteronuclear Correlation Spectroscopy. Magn. Reson. Chem 31 (1993) 287-292
41. Leenheer J.A., Rostad C.E., Gates P.M., Furlong E.T., and Ferrer I. Molecular Resolution and Fragmentation of Fulvic Acid by Electrospray Ionization/Multistage Tandem Mass Spectrometry. Anal. Chem 73 (2001) 1461-1471
42. Hunt S.M., Sheil M.M., Belov M., and Derrick P.J. Probing the Effects of Cone Potential in the Electrospray Ion Source: Consequences for the Determination of Molecular Weight Distributions of Synthetic Polymers. Anal. Chem 70 (1998) 1812-1822
43. Fyfe C.A., and McKinnon M.S. Investigation of the Thermal-Degradation of Poly(Acrylic Acid) and Poly(Methacrylic Acid) by High-Resolution C-13 CP/MAS NMR-Spectroscopy. Macromolecules 19 (1986) 1909-1912
44. McNeill I.C., and Sadeghi S.M.T. Thermal-Stability and Degradation Mechanisms of Poly(Acrylic Acid) and Its Salts. 1. Poly(Acrylic Acid). Polym. Degrad. Stab 29 (1990) 233-246
45. Otsu T., and Quach L. Head-to-Head Vinyl-Polymers. 3. Preparation and Characterization of Head-to-Head Poly(Acrylic Acid) and Its Esters. J. Polym. Sci. Part A Polym. Chem.s 19 (1981) 2377-2389