SCOPUS 정보 검색 플랫폼

Synlett

Volumn , Issue 19, 2008, Pages 3036-3040

4-(Isoxazol-3-yl)pyrimidines from pyrimidinyl nitrile oxides

(5) Choung, Wonken a Lorsbach, Beth A b Sparks, Thomas C b Ruiz, James M b Kurth, Mark J a

a UNIVERSITY OF CALIFORNIA (United States)

b DOW AGROSCIENCES LLC (United States)

Author keywords

2 aminopyrimidine; Cycloaddition; ipso substitution; Isoxazoles; Isoxazolines; Nitrile oxide

Indexed keywords

4 (ISOXAZOL 3 YL)PYRIMIDINE DERIVATIVE; NITRILE OXIDE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ADDITION REACTION; ARTICLE; BIOLOGICAL ACTIVITY; CHEMICAL PROCEDURES; CHEMICAL STRUCTURE; SYNTHESIS;

EID: 57649131062 PISSN: 09365214 EISSN: None Source Type: Journal
DOI: 10.1055/s-0028-1087346 Document Type: Article

Times cited : (11)

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- Representative Examples of 5 4-Methyl-6-(5-phenylisoxazol-3-yl)-N-propylpyrimidin-2-amine 1H NMR (300 MHz, CDCl3, δ, 7.80 (m, 2 H, 7.42 (m, 3 H, 7.10 (s, 1 H, 7.00 (s, 1 H, 3.42 (m, 2 H, 2.31 (s, 3 H, 2.18 (s, 1 H, 1.62 (m, 2 H, 0.93 (m, 3 H, 13C NMR (75 MHz, CDCl3, δ, 170.9, 162.9, 162.7, 156.3, 130.6, 129.3, 127.5, 126.1, 106.8, 105.8, 98.7, 43.5, 23.3, 23.1, 11.8. N-(Cyclopropylmethyl)-4-isopropyl-6-(5-phenylisoxazol-3-yl) pyrimidin-2-amine 1H NMR (300 MHz, CDCl3, δ, 7.60 (m, 2 H, 7.24 (m, 3 H, 6.91 (s, 1 H, 6.84 (s, 1 H, 5.22 (br s, 1 H, 3.11 (m, 2 H, 2.64 (m, 1 H, 1.27 (d, J, 7.0 Hz, 6 H, 0.82 (m, 1 H, 0.30 (m, 2 H, 0.05 (m, 2 H, 13C NMR (75 MHz, CDCl3, δ, 178.2, 170.9, 163.6, 162.8, 156.2, 130.6, 129.3, 127.5, 126.1, 104.4, 98.7, 46.8, 36.3, 21.9, 11.9, 3.7. 4-Isopropyl-6-5-phenylisoxazol-3-y
- 3): δ = 178.2, 170.9, 163.6, 162.8, 156.2, 130.6, 129.3, 127.5, 126.1, 104.4, 98.7, 46.8, 36.3, 21.9, 11.9, 3.7.

33
- 57649139889
- Representative Examples of 8 N-Cyclopentyl-3-[2-(2- methoxyethylamino)-6-methylpyrimidin-4-yl)isoxazole-5-carboxamide 1H NMR (300 MHz, CDCl3, d, 7.42 (s, 1 H, 7.10 (s, 1 H, 6.55 (br s, 1 H, 5.53 (brs, 1 H, 4.41 (m, 1 H, 3.69-3.55 (m, 4 H, 3.38 (s, 3 H, 2.39 (s, 3 H, 2.13-2.04 (m, 2 H, 1.85-1.52 (m, 6 H, 13C NMR (75 MHz, CDCl3, d, 169.7, 164.3, 163.9, 162.8, 155.5, 154.9, 107.1, 106.2, 71.5, 59.0, 51.9, 41.4, 33.3, 24.4, 24.0. N-Benzyl-3-[2, cyclopentylamino)-6-methylpyrimidin-4-yl]isoxazole-5-carboxamide 1H NMR (300 MHz, CDCl3, δ, 7.49 (s, 1 H, 7.35 (m, 5 H, 7.06 (br s, 2 H, 5.22 (d, J, 6.9 Hz, 1 H, 4.64 (d, J, 6.9 Hz, 2 H, 4.33 (m, 1 H, 2.37 (s, 3 H, 2.04 (m, 2 H, 1.72-1.24 (m, 6 H, 13C NMR 75 MHz, CDCl3, δ, 169.5, 163.9, 162.6, 162.4, 155.9, 154.8, 137.2, 129.1, 129.0, 128.2, 106.7, 106.5, 53.2, 43.8, 3
- 3): δ = 178.2, 164.1, 163.9, 162.5, 159.6, 155.8, 155.0, 129.7, 129.3, 114.5, 106.6, 104.2, 55.6, 53.3, 43.4, 36.3, 33.5, 24.0, 21.8.

34
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- 2O mixture (90:10)] had been applied (to each of eight wells) and then allowed to dry. Trays were covered with a clear self-adhesive cover, and held at 25°C, 14:10 light/dark for 6 d. Percent mortality was recorded for the larvae in each well; activity in the eight wells was then averaged,

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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.